Abstract
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:Authors: Diane Trout, Brandon King

The purpose of BioHub is to provide a queriable database that allow 
multiple annotations to be attached to a specific region of a genome. 
We intended that BioHub provide a way to link diverse annotation sources, 
by mapping identifiers in foreign databases to our unique identifier.

The core of BioHub provides a way to define a unique sequence ID (SID) that 
describes a specific genome, build, and chromosome start, stop and strand 
with the guarentee that the same region will always receive 
the same SID. 

The SID then allows us to link a variety of specialized annotation databases
with a single linking table.  We were then able to provide a Python
interface to this database to provide such useful services as:
a "spatial query" that can search the upstream or downstream 
region of a specific genome feature (identified by its SID) for features
of interest; large batch BLAST and BLAT queries; and sequence retrieval.

BioHub was written by Brandon King, Joe Roden, Cory Tobin, Matthew Goldsbury, 
and Diane Trout