System Requirements =================== SAMtools depends on the zlib library . The latest version 1.2.3 is preferred and with the latest version you can compile razip and use it to compress a FASTA file. SAMtools' faidx is able to index a razip-compressed FASTA file to save diskspace. Older zlib also works with SAMtools, but razip cannot be compiled. The text-based viewer (tview) requires the GNU ncurses library , which comes with Mac OS X and most of the modern Linux/Unix distributions. If you do not have this library installed, you can still compile the rest of SAMtools by manually modifying one line in Makefile. Compilation =========== Type `make' to compile samtools. If you have zlib >= 1.2.2.1, you can compile razip with `make razip'. Installation ============ Simply copy `samtools' and other executables/scripts in `misc' to a location you want (e.g. a directory in your $PATH). No further configurations are required.