X-Git-Url: http://woldlab.caltech.edu/gitweb/?p=samtools.git;a=blobdiff_plain;f=NEWS;h=28d6aaa81269b72f0b8cb26a971c5bd55e33c050;hp=149c090c08bc9724d677dce8a66ddf62a83da66b;hb=cefa18095b2479339b08111936313066ec548657;hpb=b27e00385f41769d03a8cca4dbd71275fc9fa906 diff --git a/NEWS b/NEWS index 149c090..28d6aaa 100644 --- a/NEWS +++ b/NEWS @@ -1,3 +1,173 @@ +Beta Release 0.1.8 (11 July, 2010) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +Notable functional changes: + + * Added the `reheader' command which replaces a BAM header with a new + header. This command is much faster than replacing header by + BAM->SAM->BAM conversions. + + * Added the `mpileup' command which computes the pileup of multiple + alignments. + + * The `index' command now stores the number of mapped and unmapped + reads in the index file. This information can be retrieved quickly by + the new `idxstats' command. + + * By default, pileup used the SOAPsnp model for SNP calling. This + avoids the floating overflow in the MAQ model which leads to spurious + calls in repetitive regions, although these calls will be immediately + filtered by varFilter. + + * The `tview' command now correctly handles CIGARs like 7I10M and + 10M1P1I10M which cause assertion failure in earlier versions. + + * Tview accepts a region like `=10,000' where `=' stands for the + current sequence name. This saves typing for long sequence names. + + * Added the `-d' option to `pileup' which avoids slow indel calling + in ultradeep regions by subsampling reads locally. + + * Added the `-R' option to `view' which retrieves alignments in read + groups listed in the specified file. + +Performance improvements: + + * The BAM->SAM conversion is up to twice faster, depending on the + characteristic of the input. + + * Parsing SAM headers with a lot of reference sequences is now much + faster. + + * The number of lseek() calls per query is reduced when the query + region contains no read alignments. + +Bug fixes: + + * Fixed an issue in the indel caller that leads to miscall of indels. + Note that this solution may not work well when the sequencing indel + error rate is higher than the rate of SNPs. + + * Fixed another issue in the indel caller which may lead to incorrect + genotype. + + * Fixed a bug in `sort' when option `-o' is applied. + + * Fixed a bug in `view -r'. + +APIs and other changes: + + * Added iterator interfaces to random access and pileup. The callback + interfaces directly call the iterator interfaces. + + * The BGZF blocks holding the BAM header are indepedent of alignment + BGZF blocks. Alignment records shorter than 64kB is guaranteed to be + fully contained in one BGZF block. This change is fully compatible + with the old version of samtools/picard. + +Changes in other utilities: + + * Updated export2sam.pl by Chris Saunders. + + * Improved the sam2vcf.pl script. + + * Added a Python version of varfilter.py by Aylwyn Scally. + +(0.1.8: 11 July 2010, r613) + + + +Beta Release 0.1.7 (10 November, 2009) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +Notable changes: + + * Improved the indel caller in complex scenariors, in particular for + long reads. The indel caller is now able to make reasonable indel + calls from Craig Venter capillary reads. + + * Rewrote single-end duplicate removal with improved + performance. Paired-end reads are not touched. + + * Duplicate removal is now library aware. Samtools remove potential + PCR/optical dupliates inside a library rather than across libraries. + + * SAM header is now fully parsed, although this functionality is not + used in merging and so on. + + * In samtools merge, optionally take the input file name as RG-ID and + attach the RG tag to each alignment. + + * Added FTP support in the RAZF library. RAZF-compressed reference + sequence can be retrieved remotely. + + * Improved network support for Win32. + + * Samtools sort and merge are now stable. + +Changes in other utilities: + + * Implemented sam2vcf.pl that converts the pileup format to the VCF + format. + + * This release of samtools is known to work with the latest + Bio-Samtools Perl module. + +(0.1.7: 10 November 2009, r510) + + + +Beta Release 0.1.6 (2 September, 2009) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +Notable changes: + + * In tview, do not show a blank screen when no reads mapped to the + corresponding region. + + * Implemented native HTTP support in the BGZF library. Samtools is now + able to directly open a BAM file on HTTP. HTTP proxy is also + supported via the "http_proxy" environmental variable. + + * Samtools is now compitable with the MinGW (win32) compiler and the + PDCurses library. + + * The calmd (or fillmd) command now calculates the NM tag and replaces + MD tags if they are wrong. + + * The view command now recognizes and optionally prints FLAG in HEXs or + strings to make a SAM file more friendly to human eyes. This is a + samtools-C extension, not implemented in Picard for the time + being. Please type `samtools view -?' for more information. + + * BAM files now have an end-of-file (EOF) marker to facilitate + truncation detection. A warning will be given if an on-disk BAM file + does not have this marker. The warning will be seen on BAM files + generated by an older version of samtools. It does NO harm. + + * New key bindings in tview: `r' to show read names and `s' to show + reference skip (N operation) as deletions. + + * Fixed a bug in `samtools merge -n'. + + * Samtools merge now optionally copies the header of a user specified + SAM file to the resultant BAM output. + + * Samtools pileup/tview works with a CIGAR with the first or the last + operation is an indel. + + * Fixed a bug in bam_aux_get(). + + +Changes in other utilies: + + * Fixed wrong FLAG in maq2sam. + + +(0.1.6: 2 September 2009, r453) + + + Beta Release 0.1.5 (7 July, 2009) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~