X-Git-Url: http://woldlab.caltech.edu/gitweb/?p=samtools.git;a=blobdiff_plain;f=NEWS;h=6b4d8aac5ede779b7efee6e02969dea40926275c;hp=82646ba812fa66f90c1ca4cf2473645f87809b31;hb=cdd6f3c76a88cf064bffafc460b358557bc603b3;hpb=8d2494d1fb7cd0fa7c63be5ffba8dd1a11457522 diff --git a/NEWS b/NEWS index 82646ba..6b4d8aa 100644 --- a/NEWS +++ b/NEWS @@ -1,3 +1,95 @@ +Beta release 0.1.12a (2 December, 2010) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +This is another bug fix release: + + * Fixed a memory violation in mpileup, which causes segfault. Release + 0.1.9 and above are affected. + + * Fixed a memory violation in the indel caller, which does not causes + segfault, but may potentially affect deletion calls in an unexpected + way. Release 0.1.10 and above are affected. + + * Fixed a bug in computing r-square in bcftools. Few are using this + functionality and it only has minor effect. + + * Fixed a memory leak in bam_fetch(). + + * Fixed a bug in writing meta information to the BAM index for the last + sequence. This bug is invisible to most users, but it is a bug anyway. + + * Fixed a bug in bcftools which causes false "DP4=0,0,0,0" annotations. + +(0.1.12: 2 December 2010, r862) + + + +Beta release 0.1.11 (21 November, 2010) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +This is mainly a bug fix release: + + * Fixed a bug in random retrieval (since 0.1.8). It occurs when reads + are retrieved from a small region containing no reads. + + * Fixed a bug in pileup (since 0.1.9). The bug causes an assertion + failure when the first CIGAR operation is a deletion. + + * Improved fault tolerence in remote access. + +One minor feature has been implemented in bcftools: + + * Added a reference-free variant calling mode. In this mode, a site is + regarded as a variat iff the sample(s) contains two or more alleles; + the meaning of the QUAL field in the VCF output is changed + accordingly. Effectively, the reference allele is irrelevant to the + result in the new mode, although the reference sequence has to be + used in realignment when SAMtools computes genotype likelihoods. + +In addition, since 0.1.10, the `pileup' command has been deprecated by +`mpileup' which is more powerful and more accurate. The `pileup' command +will not be removed in the next few releases, but new features will not +be added. + +(0.1.11: 21 November 2010, r851) + + + +Beta Release 0.1.10 (16 November, 2010) +~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ + +This release is featured as the first major improvement to the indel +caller. The method is similar to the old one implemented in the pileup +command, but the details are handled more carefully both in theory and +in practice. As a result, the new indel caller usually gives more +accurate indel calls, though at the cost of sensitivity. The caller is +implemented in the mpileup command and is invoked by default. It works +with multiple samples. + +Other notable changes: + + * With the -r option, the calmd command writes the difference between + the original base quality and the BAQ capped base quality at the BQ + tag but does not modify the base quality. Please use -Ar to overwrite + the original base quality (the 0.1.9 behavior). + + * Allow to set a maximum per-sample read depth to reduce memory. In + 0.1.9, most of memory is wasted for the ultra high read depth in some + regions (e.g. the chr1 centromere). + + * Optionally write per-sample read depth and per-sample strand bias + P-value. + + * Compute equal-tail (Bayesian) credible interval of site allele + frequency at the CI95 VCF annotation. + + * Merged the vcfutils.pl varFilter and filter4vcf for better SNP/indel + filtering. + +(0.1.10: 16 November 2010, r829) + + + Beta Release 0.1.9 (27 October, 2010) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~