X-Git-Url: http://woldlab.caltech.edu/gitweb/?p=samtools.git;a=blobdiff_plain;f=bam_index.c;h=66d8eb8a896ab5a0a4decf612e65eac158e92cbf;hp=51c27014da0f9f010b563db92112f71d7ad6bdd6;hb=e582623cf8c4778c7dc792318635821d3c494b0d;hpb=1539c893f863596db71ab2af75a802e935496940 diff --git a/bam_index.c b/bam_index.c index 51c2701..66d8eb8 100644 --- a/bam_index.c +++ b/bam_index.c @@ -172,17 +172,21 @@ bam_index_t *bam_index_core(bamFile fp) save_bin = save_tid = last_tid = last_bin = 0xffffffffu; save_off = last_off = bam_tell(fp); last_coor = 0xffffffffu; - n_mapped = n_unmapped = n_no_coor = off_end = 0; + n_mapped = n_unmapped = n_no_coor = off_end = 0; off_beg = off_end = bam_tell(fp); while ((ret = bam_read1(fp, b)) >= 0) { if (c->tid < 0) ++n_no_coor; - if (last_tid != c->tid) { // change of chromosomes + if (last_tid < c->tid || (last_tid >= 0 && c->tid < 0)) { // change of chromosomes last_tid = c->tid; last_bin = 0xffffffffu; - } else if (last_coor > c->pos) { + } else if ((uint32_t)last_tid > (uint32_t)c->tid) { + fprintf(stderr, "[bam_index_core] the alignment is not sorted (%s): %d-th chr > %d-th chr\n", + bam1_qname(b), last_tid+1, c->tid+1); + return NULL; + } else if ((int32_t)c->tid >= 0 && last_coor > c->pos) { fprintf(stderr, "[bam_index_core] the alignment is not sorted (%s): %u > %u in %d-th chr\n", bam1_qname(b), last_coor, c->pos, c->tid+1); - exit(1); + return NULL; } if (c->tid >= 0) insert_offset2(&idx->index2[b->core.tid], b, last_off); if (c->bin != last_bin) { // then possibly write the binning index @@ -203,7 +207,7 @@ bam_index_t *bam_index_core(bamFile fp) if (bam_tell(fp) <= last_off) { fprintf(stderr, "[bam_index_core] bug in BGZF/RAZF: %llx < %llx\n", (unsigned long long)bam_tell(fp), (unsigned long long)last_off); - exit(1); + return NULL; } if (c->flag & BAM_FUNMAP) ++n_unmapped; else ++n_mapped; @@ -222,7 +226,7 @@ bam_index_t *bam_index_core(bamFile fp) ++n_no_coor; if (c->tid >= 0 && n_no_coor) { fprintf(stderr, "[bam_index_core] the alignment is not sorted: reads without coordinates prior to reads with coordinates.\n"); - exit(1); + return NULL; } } } @@ -473,6 +477,10 @@ int bam_index_build2(const char *fn, const char *_fnidx) } idx = bam_index_core(fp); bam_close(fp); + if(idx == 0) { + fprintf(stderr, "[bam_index_build2] fail to index the BAM file.\n"); + return -1; + } if (_fnidx == 0) { fnidx = (char*)calloc(strlen(fn) + 5, 1); strcpy(fnidx, fn); strcat(fnidx, ".bai");