PC-2 p<0.000010 High/Low	PC-2 Value	ProbeId	Name	Aliases	LocusLink	Description	Function	Protein_Families	
high	36.3193227358	208791_at	CLU	APOJ;CLI;CLU;MGC24903;SGP-2;SGP2;SP-40;TRPM-2;TRPM2	1191	clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J)	apoptosis (GO:0006915);cell death (GO:0008219);fertilization (sensu Animalia) (GO:0007338);lipid metabolism (GO:0006629);plasma glycoprotein (GO:0005211)	Bipartite nuclear localization signal (IPR001472);Clusterin (IPR000753)	
high	33.4946924947	209072_at	MBP	MBP	4155	myelin basic protein	DNA binding (GO:0003677);immune response (GO:0006955);structural constituent of myelin sheath (GO:0019911);structural molecule activity (GO:0005198)	Myelin basic protein (IPR000548)	
high	31.244244289	203382_s_at	APOE	APOE	348	apolipoprotein E	antioxidant activity (GO:0016209);apolipoprotein E receptor binding (GO:0050749);beta-amyloid binding (GO:0001540);cholesterol homeostasis (GO:0042632);cholesterol metabolism (GO:0008203);circulation (GO:0008015);cytoskeleton organization and biogenesis (GO:0007010);development (GO:0007275);heparin binding (GO:0008201);immune response (GO:0006955);intracellular transport (GO:0046907);learning and/or memory (GO:0007611);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);low-density lipoprotein receptor binding (GO:0050750);plasma protein (GO:0005209);receptor binding (GO:0005102);response to reactive oxygen species (GO:0000302);tau protein binding (GO:0048156)	Apolipoprotein A1/A4/E (IPR000074)	
high	31.05758958	200795_at	SPARCL1	HEVIN;MAST9;SC1;SPARCL1	8404	SPARC-like 1 (mast9, hevin)	calcium ion binding (GO:0005509)	Calcium-binding EF-hand (IPR002048);Follistatin-like, N-terminal (IPR003645);Osteonectin-like (IPR001999);Proteinase inhibitor I1, Kazal (IPR002350)	
high	30.1257097702	210198_s_at	PLP1	MMPL;PLP;PLP/DM20;PLP1;PMD;SPG2	5354	proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated)	structural molecule activity (GO:0005198)	Myelin proteolipid protein PLP (IPR001614)	
high	30.0095274613	212233_at	MAP1B	FUTSCH;MAP1B;MAP5	4131	microtubule-associated protein 1B	microtubule-based process (GO:0007017);structural molecule activity (GO:0005198)	Bipartite nuclear localization signal (IPR001472)	
high	29.5471611125	217414_x_at	HBA2	HBA1;HBA2	3040	hemoglobin, alpha 2	oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810)	Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339)	
high	29.3024800979	201427_s_at	SEPP1	SEPP1;SeP	6414	selenoprotein P, plasma, 1	response to oxidative stress (GO:0006979);selenium binding (GO:0008430)	Selenoprotein P, C-terminal (IPR007672);Selenoprotein P, N-terminal (IPR007671)	
high	28.8419386677	202508_s_at	SNAP25	FLJ23079;SNAP;SNAP-25;SNAP25;bA416N4.2;dJ1068F16.2	6616	synaptosomal-associated protein, 25kDa	molecular_function unknown (GO:0005554);neurotransmitter secretion (GO:0007269);regulation of synapse (GO:0007273)	SNAP-25 (IPR000928);Target SNARE coiled-coil domain (IPR000727)	
high	28.8112192557	201525_at	APOD	APOD	347	apolipoprotein D	high-density lipoprotein (GO:0005321);high-density lipoprotein binding (GO:0008035);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transporter activity (GO:0005319);transport (GO:0006810);transporter activity (GO:0005215)	Apolipoprotein D (IPR002969);Bacterial lipocalin (IPR002446);Invertebrate colouration protein (IPR003057);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Retinol-binding protein (IPR002449)	
low	-19.1440453016	204286_s_at	PMAIP1	APR;NOXA;PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	oncogenesis (GO:0007048)	None	
low	-19.6899419467	213416_at	ITGA4	CD49D;CD49d;ITGA4	3676	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	cell adhesion (GO:0007155);cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872)	Integrins alpha chain (IPR000413)	
low	-19.7687483821	202546_at	VAMP5	EDB;MYOBREVIN;VAMP5;VAMP8	10791	vesicle-associated membrane protein 5 (myobrevin)	muscle development (GO:0007517);protein complex assembly (GO:0006461)	Synaptobrevin (IPR001388)	
low	-19.7917323763	213975_s_at	LYZ	LYZ	4069	lysozyme (renal amyloidosis)	amyloid protein (GO:0005208);antimicrobial humoral response (sensu Protostomia) (GO:0006960);bacteriolytic toxin activity (GO:0015642);carbohydrate metabolism (GO:0005975);cell wall catabolism (GO:0016998);cytolysis (GO:0019835);hydrolase activity, acting on glycosyl bonds (GO:0016798);inflammatory response (GO:0006954);lysin activity (GO:0015465);lysozyme activity (GO:0003796);structural molecule activity (GO:0005198)	Glycoside hydrolase, family 22 (IPR001916);Glycoside hydrolase, family 22, lysozyme (IPR000974)	
low	-19.9008322293	204220_at	GMFG	GMF-GAMMA;GMFG	9535	glia maturation factor, gamma	actin binding (GO:0003779);enzyme activator activity (GO:0008047);growth factor activity (GO:0008083);protein amino acid phosphorylation (GO:0006468);protein kinase inhibitor activity (GO:0004860)	Actin-binding, cofilin/tropomyosin type (IPR002108)	
low	-19.9441085755	202864_s_at	SP100	SP100	6672	nuclear antigen Sp100	DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001)	Bipartite nuclear localization signal (IPR001472);HMG1/2 (high mobility group) box (IPR000910);High mobility group proteins HMG1 and HMG2 (IPR000135);SAND (IPR000770);Sp100 (IPR004865)	
low	-20.5963420505	204285_s_at	PMAIP1	APR;NOXA;PMAIP1	5366	phorbol-12-myristate-13-acetate-induced protein 1	oncogenesis (GO:0007048)	None	
low	-20.6997861188	212587_s_at	PTPRC	B220;CD45;GP180;LCA;LY5;PTPRC;T200	5788	protein tyrosine phosphatase, receptor type, C	cell surface receptor linked signal transduction (GO:0007166);hydrolase activity (GO:0016787);prenylated protein tyrosine phosphatase activity (GO:0004727);protein amino acid dephosphorylation (GO:0006470);protein tyrosine phosphatase activity (GO:0004725);transmembrane receptor protein tyrosine phosphatase activity (GO:0005001)	Fibronectin, type III (IPR003961);Protein tyrosine phosphatase, catalytic region (IPR003595);Tyrosine specific protein phosphatase (IPR000242);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387)	
low	-21.2814820005	203047_at	STK10	LOK;PRO2729;STK10	6793	serine/threonine kinase 10	kinase activity (GO:0016301);protein amino acid phosphorylation (GO:0006468);protein serine/threonine kinase activity (GO:0004674)	Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245)	
low	-21.5690095578	209083_at	CORO1A	CLABP;CLIPINA;CORO1A;Clabp TACO;HAST;HAST3;HCORO1;M-PST;STM;SULT1A3;TACO;TL-PST;p57	11151	coronin, actin binding protein, 1A	DNA repair (GO:0006281);actin binding (GO:0003779);amine biosynthesis (GO:0009309);amine metabolism (GO:0009308);aryl sulfotransferase activity (GO:0004062);catecholamine metabolism (GO:0006584);cell motility (GO:0006928);nuclease activity (GO:0004518);phagosome formation (GO:0006912);steroid metabolism (GO:0008202);structural molecule activity (GO:0005198);sulfotransferase activity (GO:0008146);transferase activity (GO:0016740);transport (GO:0006810)	Excinuclease ABC, C subunit, N-terminal (IPR000305);Sulfotransferase (IPR000863)	
low	-22.44400857	201288_at	ARHGDIB	ARHGDIB;GDIA2;GDID4;LYGDI;RAP1GN1	397	Rho GDP dissociation inhibitor (GDI) beta	GTPase activator activity (GO:0005096);Rho GDP-dissociation inhibitor activity (GO:0005094);Rho protein signal transduction (GO:0007266);actin cytoskeleton organization and biogenesis (GO:0030036);actin cytoskeleton reorganization (GO:0007012);development (GO:0007275);immune response (GO:0006955);negative regulation of cell adhesion (GO:0007162)	Immunoglobulin-like (IPR007110);RHO protein GDP dissociation inhibitor (IPR000406)	
low	-22.5643000351	213160_at	DOCK2	DOCK2;KIAA0209	1794	dedicator of cytokinesis 2	GTPase activator activity (GO:0005096);Rac guanyl-nucleotide exchange factor activity (GO:0030676);T-cell receptor binding (GO:0042608);actin cytoskeleton organization and biogenesis (GO:0030036);lymphocyte chemotaxis (GO:0048247);small GTPase mediated signal transduction (GO:0007264)	SH3 (IPR001452)	
low	-22.7434530932	216237_s_at	MCM5	CDC46;MCM5;MGC5315;P1-CDC46	4174	MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)	ATP binding (GO:0005524);DNA binding (GO:0003677);DNA replication (GO:0006260);DNA-dependent ATPase activity (GO:0008094);cell cycle regulator (GO:0003750)	Bipartite nuclear localization signal (IPR001472);MCM (IPR001208);MCM protein 5 (IPR008048)	
low	-22.9544420529	209040_s_at	PSMB8	D6S216;D6S216E;LMP7;MGC1491;PSMB8;RING10	5696	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7)	endopeptidase activity (GO:0004175);immune response (GO:0006955);peptidase activity (GO:0008233);proteasome endopeptidase activity (GO:0004299);proteolysis and peptidolysis (GO:0006508);ubiquitin-dependent protein catabolism (GO:0006511)	20S proteasome, A and B subunits (IPR001353);Peptidase T1A, proteasome beta-subunit (IPR000243)	
low	-22.996785727	212873_at	HA-1	HA-1;HLA-HA1;KIAA0223	23526	minor histocompatibility antigen HA-1	intracellular signaling cascade (GO:0007242)	Bipartite nuclear localization signal (IPR001472);Cdc15/Fes/CIP4 (IPR001060);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198)	
low	-23.7923180278	207419_s_at	RAC2	EN-7;HSPC022;RAC2	5880	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	GTP binding (GO:0005525);GTPase activity (GO:0003924);Rho small monomeric GTPase activity (GO:0003931);signal transduction (GO:0007165);small GTPase mediated signal transduction (GO:0007264)	Ras GTPase superfamily (IPR001806);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225)	
low	-24.3697952913	204661_at	CDW52	CD52;CDW52	1043	CDW52 antigen (CAMPATH-1 antigen)	lymphocyte antigen (GO:0005557)	None	
low	-25.3229596592	34210_at	CDW52	CD52;CDW52	1043	CDW52 antigen (CAMPATH-1 antigen)	lymphocyte antigen (GO:0005557)	None	
low	-25.4950916361	208998_at	UCP2	SLC25A8;UCP2;UCPH	7351	uncoupling protein 2 (mitochondrial, proton carrier)	binding (GO:0005488);mitochondrial transport (GO:0006839);proton transport (GO:0015992);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215);uncoupling protein activity (GO:0015302)	Adenine nucleotide translocator 1 (IPR002113);Mitochondrial brown fat uncoupling protein (IPR002030);Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993)