PC-8 p<0.000010 High/Low PC-8 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 21.5694081571 210122_at PRM2 PRM2 5620 protamine 2 DNA binding (GO:0003677);DNA packaging (GO:0006323);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);spermatogenesis (GO:0007283) Bipartite nuclear localization signal (IPR001472);Protamine 2, PRM2 (IPR000492) high 21.331453569 206358_at PRM1 PRM1 5619 protamine 1 DNA binding (GO:0003677);DNA packaging (GO:0006323);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);spermatogenesis (GO:0007283) Bipartite nuclear localization signal (IPR001472);Protamine P1 (IPR000221) high 16.2425803762 215734_at IMAGE:4215339 IMAGE:4215339 113177 hypothetical protein IMAGE:4215339 None None high 15.0662264099 211748_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 14.9731710893 206568_at TNP1 TNP1;TP1 7141 transition protein 1 (during histone to protamine replacement) DNA binding (GO:0003677);chromatin silencing (GO:0006342);chromosome condensation (GO:0000068);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome disassembly (GO:0006337);sexual reproduction (GO:0019953);single strand break repair (GO:0000012);sperm motility (GO:0030317);spermatogenesis (GO:0007283) Nuclear transition protein 1 (IPR001319) high 14.7892720096 214183_s_at TKTL1 TKR;TKT2;TKTL1 8277 transketolase-like 1 calcium ion binding (GO:0005509);glucose catabolism (GO:0006007);thiamin metabolism (GO:0006772);transferase activity (GO:0016740);transketolase activity (GO:0004802) Transketolase, C terminal (IPR005476);Transketolase, C-terminal-like (IPR009014);Transketolase, N terminal (IPR005474);Transketolase, central region (IPR005475) high 14.7878573096 206112_at ANKRD7 ANKRD7;TSA806 56311 ankyrin repeat domain 7 male gonad development (GO:0008584) None high 14.5390750125 210415_s_at ODF2 MGC9034;ODF2;ODF2/1;ODF2/2;ODF84 4957 outer dense fiber of sperm tails 2 structural molecule activity (GO:0005198) Bipartite nuclear localization signal (IPR001472) high 14.2291559061 212187_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 13.8606531426 211663_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 13.3968600296 214400_at INSL3 INSL3;RLF;RLNL 3640 insulin-like 3 (Leydig cell) ATP binding (GO:0005524);Janus kinase activity (GO:0004718);cell growth and/or maintenance (GO:0008151);cell-cell signaling (GO:0007267);hormone activity (GO:0005179);insulin receptor binding (GO:0005158);intracellular signaling cascade (GO:0007242);physiological process (GO:0007582);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor binding (GO:0005102);signal transducer activity (GO:0004871);spermatogenesis (GO:0007283);transferase activity (GO:0016740) Band 4.1 (IPR000299);FERM (IPR009065);Insulin/IGF/relaxin (IPR004825);Janus kinase 3, JAK3 (IPR009130);Janus kinase, JAK (IPR009127);Peptidase, eukaryotic cysteine peptidase active site (IPR000169);Proline-rich region (IPR000694);Protein kinase (IPR000719);SH2 motif (IPR000980);Tyrosine protein kinase (IPR001245) high 13.3302541793 220298_s_at SPATA6 FLJ10007;SPATA6;SRF-1;SRF1 54558 spermatogenesis associated 6 None None high 13.1052412019 210262_at CRISP2 CRISP-2;CRISP2;GAPDL5;TPX1;TSP1 7180 cysteine-rich secretory protein 2 None Allergen V5/Tpx-1 related (IPR001283) high 12.9361179978 207918_s_at TSPY2 TSPY2;TSPYQ1 64591 testis specific protein, Y-linked 2 cell proliferation (GO:0008283);sex differentiation (GO:0007548);spermatogenesis (GO:0007283) Bipartite nuclear localization signal (IPR001472);Nucleosome assembly protein (NAP) (IPR002164) high 12.9196733436 206406_at MCSP HSMCSGEN1;MCS;MCSP;MGC26305;MGC26519;SMCP 4184 mitochondrial capsule selenoprotein fertilization (sensu Animalia) (GO:0007338);molecular_function unknown (GO:0005554);sperm motility (GO:0030317) None high 12.6228852775 202178_at PRKCZ PKC2;PRKCZ 5590 protein kinase C, zeta ATP binding (GO:0005524);atypical protein kinase C activity (GO:0004700);cAMP-dependent protein kinase activity (GO:0004691);diacylglycerol binding (GO:0019992);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);signal transduction (GO:0007165);transferase activity (GO:0016740) Octicosapeptide/Phox/Bem1p (IPR000270);Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 12.60529824 206310_at SPINK2 HUSI-II;SPINK2 6691 serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) endopeptidase inhibitor activity (GO:0004866);serine-type endopeptidase inhibitor activity (GO:0004867) Bipartite nuclear localization signal (IPR001472);Proteinase inhibitor I1, Kazal (IPR002350);Proteinase inhibitor I1, Kazal metazoa (IPR001239) high 12.5584052819 gnf1h09048_at DNCL2B DNCL2B;DNLC2B 83657 dynein, cytoplasmic, light polypeptide 2B microtubule motor activity (GO:0003777);microtubule-based movement (GO:0007018);microtubule-based process (GO:0007017);motor activity (GO:0003774);protein binding (GO:0005515) Roadblock/LC7 family (IPR004942) high 12.4797356834 221611_s_at PHF7 DKFZp434L1850;HSPC045;HSPC226;MGC26088;NYD-SP6;PHF7 51533 PHD finger protein 7 DNA binding (GO:0003677) Zn-finger, RING (IPR001841);Zn-finger-like, PHD finger (IPR001965) high 12.3987786274 220425_x_at ROPN1 DKFZp434B1222;ODF6;RHPNAP1;ROPN1;ropporin 54763 ropporin, rhophilin associated protein 1 Rho protein signal transduction (GO:0007266);cAMP-dependent protein kinase regulator activity (GO:0008603);cell-cell adhesion (GO:0016337);fusion of sperm to egg plasma membrane (GO:0007342);porin activity (GO:0015288);protein heterodimerization activity (GO:0046982);protein homodimerization activity (GO:0042803);receptor signaling complex scaffold activity (GO:0030159);signal transduction (GO:0007165);sperm motility (GO:0030317);spermatogenesis (GO:0007283) cAMP-dependent protein kinase regulator, type II PKA R subunit (IPR003117) high 12.2987277971 214572_s_at INSL3 INSL3;RLF;RLNL 3640 insulin-like 3 (Leydig cell) ATP binding (GO:0005524);Janus kinase activity (GO:0004718);cell growth and/or maintenance (GO:0008151);cell-cell signaling (GO:0007267);hormone activity (GO:0005179);insulin receptor binding (GO:0005158);intracellular signaling cascade (GO:0007242);physiological process (GO:0007582);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor binding (GO:0005102);signal transducer activity (GO:0004871);spermatogenesis (GO:0007283);transferase activity (GO:0016740) Band 4.1 (IPR000299);FERM (IPR009065);Insulin/IGF/relaxin (IPR004825);Janus kinase 3, JAK3 (IPR009130);Janus kinase, JAK (IPR009127);Peptidase, eukaryotic cysteine peptidase active site (IPR000169);Proline-rich region (IPR000694);Protein kinase (IPR000719);SH2 motif (IPR000980);Tyrosine protein kinase (IPR001245) high 12.081888885 221630_s_at DDX4 DDX4;VASA 54514 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 ATP binding (GO:0005524);ATP-dependent helicase activity (GO:0008026);development (GO:0007275);hydrolase activity (GO:0016787);nucleic acid binding (GO:0003676) ATP-dependent helicase, DEAD-box (IPR000629);DEAD/DEAH box helicase (IPR001410);Helicase, C-terminal (IPR001650) high 11.9206038194 210189_at HSPA1L HSP70-HOM;HSPA1L;hum70t 3305 heat shock 70kDa protein 1-like ATP binding (GO:0005524);heat shock protein activity (GO:0003773) Bipartite nuclear localization signal (IPR001472);Fe-S protein assembly chaperone HscA (IPR010236);Heat shock protein Hsp70 (IPR001023) high 11.8245953628 gnf1h00769_at ECRG4 ECRG4 84417 esophageal cancer related gene 4 protein None None high 11.6680314019 207021_at ZPBP SP38;ZPBP;ZPBP1 11055 zona pellucida binding protein None Immunoglobulin-like (IPR007110);Zona-pellucida-binding (IPR010857) high 11.3772623406 207344_at AKAP3 AKAP110;AKAP3;FSP95;PRKA3;SOB1 10566 A kinase (PRKA) anchor protein 3 cell motility (GO:0006928);fertilization (sensu Animalia) (GO:0007338);kinase activity (GO:0016301);protein kinase A anchoring activity (GO:0005079);protein kinase A binding (GO:0051018) A-kinase anchor 110 kDa (IPR008382) high 11.0469825185 204849_at TCFL5 CHA;E2BP-1;MGC46135;TCFL5 10732 transcription factor-like 5 (basic helix-loop-helix) DNA binding (GO:0003677);cell proliferation (GO:0008283);development (GO:0007275);protein binding (GO:0005515);regulation of cell differentiation (GO:0045595);regulation of cell proliferation (GO:0042127);spermatogenesis (GO:0007283);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) Basic helix-loop-helix dimerization domain bHLH (IPR001092);Bipartite nuclear localization signal (IPR001472) high 10.9902227439 213996_at YPEL1 FKSG3;YPEL1 29799 yippee-like 1 (Drosophila) None Yippee-like protein (IPR004910) high 10.968342413 208791_at CLU APOJ;CLI;CLU;MGC24903;SGP-2;SGP2;SP-40;TRPM-2;TRPM2 1191 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) apoptosis (GO:0006915);cell death (GO:0008219);fertilization (sensu Animalia) (GO:0007338);lipid metabolism (GO:0006629);plasma glycoprotein (GO:0005211) Bipartite nuclear localization signal (IPR001472);Clusterin (IPR000753) high 10.8437685575 207144_s_at CITED1 CITED1;MSG1 4435 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 transcription factor activity (GO:0003700) CITED (IPR007576) high 10.7934347163 gnf1h08327_at CKLFSF2 CKLFSF2;FLJ25732;MGC39436 146225 chemokine-like factor super family 2 DNA binding (GO:0003677);chemotaxis (GO:0006935);cytokine activity (GO:0005125) Marvel (IPR008253) high 10.7407849932 221252_s_at GSG1 GSG1;MGC3146 83445 germ cell associated 1 None None high 10.7002616889 210069_at CPT1B CHETK;CHKB;CHKL;CPT1-M;CPT1B;KIAA1670;M-CPT1 1375 carnitine palmitoyltransferase 1B (muscle) acyltransferase activity (GO:0008415);carnitine O-palmitoyltransferase activity (GO:0004095);choline kinase activity (GO:0004103);ethanolamine kinase activity (GO:0004305);fatty acid beta-oxidation (GO:0006635);fatty acid metabolism (GO:0006631);transferase activity (GO:0016740);transport (GO:0006810) Acyltransferase ChoActase/COT/CPT (IPR000542);Choline/ethanolamine kinase (IPR002573);Proline-rich region (IPR000694) high 10.6544065989 gnf1h01057_at BOLL BOLL;BOULE 66037 bol, boule-like (Drosophila) RNA binding (GO:0003723);nucleic acid binding (GO:0003676);spermatogenesis (GO:0007283) RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 10.5933504966 205186_at DNALI1 DNALI1;P28;hp28 7802 dynein, axonemal, light intermediate polypeptide 1 axonemal motor activity (GO:0003775);cell motility (GO:0006928);fertilization (sensu Animalia) (GO:0007338);microtubule motor activity (GO:0003777) None high 10.5400978104 209443_at SERPINA3 AACT;ACT;PAI3;PCI;PLANH3;PROCI;SERPINA3;SERPINA5 12 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 DNA binding (GO:0003677);acute-phase response (GO:0006953);chymotrypsin inhibitor activity (GO:0030569);endopeptidase inhibitor activity (GO:0004866);inflammatory response (GO:0006954);plasma glycoprotein (GO:0005211);plasma protein (GO:0005209);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867);serpin (GO:0004868) Proteinase inhibititor I4, serpin (IPR000215) high 10.5282437551 201497_x_at MYH11 MYH11;SMHC;SMMHC 4629 myosin, heavy polypeptide 11, smooth muscle ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);cell growth and/or maintenance (GO:0008151);motor activity (GO:0003774);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941) Bipartite nuclear localization signal (IPR001472);IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928) high 10.4767234582 220501_at ACTL7A ACTL7A 10881 actin-like 7A structural constituent of cytoskeleton (GO:0005200) Actin/actin-like (IPR004000) high 10.4629922987 220922_s_at SPANXB1 SPANX;SPANXB;SPANXB1;SPANXB2 64649 SPANX family, member B1 molecular_function unknown (GO:0005554);spermatid development (GO:0007286) Sperm proteins associated with nucleus, mapped to X chromosome (IPR010007) high 10.4245128191 215622_x_at AL137671 None None None None Zn-finger, RING (IPR001841) high 10.3122521925 203919_at TCEA2 TCEA2;TFIIS 6919 transcription elongation factor A (SII), 2 defense response (GO:0006952);transcription (GO:0006350);transcription factor activity (GO:0003700);transcriptional elongation regulator activity (GO:0003711) Transcription elongation factor S-II (IPR006289);Transcription elongation factor S-II, N-terminal (IPR003617);Transcription elongation factor S-II, central region (IPR003618);Transcription factor TFIIS (IPR001222) high 10.2638022552 220378_at TCP11 D6S230E;TCP11 6954 t-complex 11 (mouse) development (GO:0007275) T-complex 11 (IPR008862) high 10.2632434315 209403_at TBC1D3 PRC17;TBC1D3 84218 TBC1 domain family, member 3 GTPase activator activity (GO:0005096);cell growth and/or maintenance (GO:0008151) RabGAP/TBC domain (IPR000195) high 10.2553071531 219587_at TTC12 FLJ13859;FLJ20535;TPARM;TTC12 54970 tetratricopeptide repeat domain 12 None ARM repeat fold (IPR008938);TPR-like (IPR008941) high 10.2352038015 204784_s_at MLF1 MLF1 4291 myeloid leukemia factor 1 cell differentiation (GO:0030154);hemopoiesis (GO:0030097);protein binding (GO:0005515);protein domain specific binding (GO:0019904) None high 10.1040146597 34210_at CDW52 CD52;CDW52 1043 CDW52 antigen (CAMPATH-1 antigen) lymphocyte antigen (GO:0005557) None high 9.96789849252 214296_x_at IMAGE:4215339 IMAGE:4215339 113177 hypothetical protein IMAGE:4215339 None None high 9.94749951109 220205_at TPTE PTEN2;TPTE 7179 transmembrane phosphatase with tensin homology cation channel activity (GO:0005261);cation transport (GO:0006812);hydrolase activity (GO:0016787);phosphoprotein phosphatase activity (GO:0004721);prenylated protein tyrosine phosphatase activity (GO:0004727);protein amino acid dephosphorylation (GO:0006470);protein tyrosine phosphatase activity (GO:0004725);signal transduction (GO:0007165) C2 calcium/lipid-binding domain, CaLB (IPR008973);Cation channel, non-ligand gated (IPR005820);Cytochrome c, class I (IPR003088);Cytochrome c, class IA/ IB (IPR002327);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 9.86995533363 gnf1h09340_s_at MGC33608 MGC33608 284257 hypothetical protein MGC33608 None None high 9.85676823331 219229_at SLCO3A1 OATP-D;OATP3A1;SLC21A11;SLCO3A1 28232 solute carrier organic anion transporter family, member 3A1 ion transport (GO:0006811);transporter activity (GO:0005215) Organic anion transporter polypeptide (OATP), C-terminal (IPR004157);Organic anion transporter polypeptide (OATP), N-terminal (IPR004156) high 9.83779224897 210279_at GPR18 GPR18 2841 G protein-coupled receptor 18 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);purinergic nucleotide receptor activity\, G-protein coupled (GO:0045028);rhodopsin-like receptor activity (GO:0001584) Rhodopsin-like GPCR superfamily (IPR000276) high 9.83326012101 222351_at PPP2R1B MGC26454;PPP2R1B 5519 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform RNA splicing (GO:0008380);antigen binding (GO:0003823);negative regulation of cell growth (GO:0030308);protein amino acid dephosphorylation (GO:0006470);protein binding (GO:0005515);protein complex assembly (GO:0006461);protein heterodimerization activity (GO:0046982);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2A regulator activity (GO:0008601);regulation of Wnt receptor signaling pathway (GO:0030111);regulation of cell adhesion (GO:0030155);regulation of cell differentiation (GO:0045595);response to organic substance (GO:0010033);second-messenger-mediated signaling (GO:0019932);tumor suppressor (GO:0008181) ARM repeat fold (IPR008938) high 9.71360097001 208107_s_at LOC81691 DKFZp434J0315;LOC81691 81691 exonuclease NEF-sp exonuclease activity (GO:0004527);nucleic acid binding (GO:0003676) Exonuclease (IPR006055);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 9.71358990618 219984_s_at HRASLS A-C1;H-REV107;HRASLS 57110 HRAS-like suppressor None NC (IPR007053) high 9.69776065268 220179_at DPEP3 DPEP3 64180 dipeptidase 3 dipeptidyl-peptidase activity (GO:0008239);membrane dipeptidase activity (GO:0004237);proteolysis and peptidolysis (GO:0006508) Peptidase M19, renal dipeptidase (IPR008257) high 9.68116041336 gnf1h09964_at gnf1h09964_at None None None None None high 9.62231372343 219945_at DDX25 DDX25;GRTH 29118 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 ATP binding (GO:0005524);ATP-dependent helicase activity (GO:0008026);RNA binding (GO:0003723);RNA helicase activity (GO:0003724);adenosinetriphosphatase (GO:0004002);hydrolase activity (GO:0016787);nucleic acid binding (GO:0003676);spermatogenesis (GO:0007283);translation activator activity (GO:0008494) ATP-dependent helicase, DEAD-box (IPR000629);DEAD/DEAH box helicase (IPR001410);Helicase, C-terminal (IPR001650) high 9.60280951111 211796_s_at 211796_s_at None None None None Immunoglobulin C-type (IPR003597);Immunoglobulin/major histocompatibility complex (IPR003006) high 9.60115081705 220498_at IKBKAP ACTL7B;DYS;IKAP;IKBKAP 8518 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein immune response (GO:0006955);kinase activity (GO:0016301);phosphorylase kinase regulator activity (GO:0008607);protein amino acid phosphorylation (GO:0006468);protein complex assembly (GO:0006461);signal transducer activity (GO:0004871);structural constituent of cytoskeleton (GO:0005200) Actin/actin-like (IPR004000);IKI3 family (IPR006849);TPR-like (IPR008941) high 9.58259625706 222106_at PRND DOPPEL;DPL;MGC41841;PRND;PrPLP;dJ1068H6.4 23627 prion protein 2 (dublet) pathogenesis (GO:0009405) Prion protein (IPR000817) high 9.5738832891 222075_s_at OAZ3 OAZ-t;OAZ3 51686 ornithine decarboxylase antizyme 3 ornithine decarboxylase inhibitor activity (GO:0008073);spermatogenesis (GO:0007283) Ornithine decarboxylase antizyme (IPR002993) high 9.54744992101 gnf1h00812_at LOC84643 LOC84643 84643 kinesin protein ATP binding (GO:0005524);microtubule-based process (GO:0007017);motor activity (GO:0003774) Kinesin, motor region (IPR001752) high 9.53589178389 gnf1h00537_at ASP ASP 83853 AKAP-associated sperm protein cAMP-dependent protein kinase regulator activity (GO:0008603);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);cAMP-dependent protein kinase regulator, type II PKA R subunit (IPR003117) high 9.52893795887 gnf1h09192_at LOC127540 LOC127540;dJ1007G16.5 127540 HMG2 like DNA binding (GO:0003677) Bipartite nuclear localization signal (IPR001472);HMG1/2 (high mobility group) box (IPR000910);High mobility group box (IPR009071);High mobility group proteins HMG1 and HMG2 (IPR000135) high 9.52729965884 215215_s_at LOC81691 DKFZp434J0315;LOC81691 81691 exonuclease NEF-sp exonuclease activity (GO:0004527);nucleic acid binding (GO:0003676) Exonuclease (IPR006055);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 9.51811946774 218870_at ARHGAP15 ARHGAP15;BM046 55843 Rho GTPase activating protein 15 None Pleckstrin-like (IPR001849);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198);Spectrin/pleckstrin-like (IPR001605) high 9.51445027746 gnf1h10339_at C6orf81 C6orf81;FLJ25390 221481 chromosome 6 open reading frame 81 None ARM repeat fold (IPR008938) high 9.48292995146 222068_s_at LOC123872 LOC123872 123872 similar to RIKEN cDNA 4930457P18 None Proline-rich region (IPR000694) high 9.45953668999 219704_at YBX2 MGC45104;MSY2;YBX2 51087 germ cell specific Y-box binding protein DNA binding (GO:0003677);RNA binding (GO:0003723);spermatogenesis (GO:0007283);transcription from Pol II promoter (GO:0006366) Cold-shock DNA-binding domain (IPR002059);Nucleic acid-binding OB-fold (IPR008994);Proline-rich region (IPR000694) high 9.41955487291 1405_i_at CCL5 CCL5;D17S136E;MGC17164;RANTES;SCYA5;SISd;TCP228 6352 chemokine (C-C motif) ligand 5 antiviral response protein activity (GO:0003800);calcium ion homeostasis (GO:0006874);cell adhesion (GO:0007155);cell motility (GO:0006928);cell-cell signaling (GO:0007267);cellular defense response (GO:0006968);chemokine activity (GO:0008009);chemotaxis (GO:0006935);exocytosis (GO:0006887);immune response (GO:0006955);inflammatory response (GO:0006954);receptor binding (GO:0005102);response to oxidative stress (GO:0006979);response to virus (GO:0009615);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Small chemokine, C-C subfamily (IPR000827);Small chemokine, interleukin-8 like (IPR001811) high 9.40505874587 215495_s_at SAMD4 DKFZp434H0350;KIAA1053;SAMD4 23034 sterile alpha motif domain containing 4 None Sterile alpha motif SAM (IPR001660) high 9.39481309434 220426_at MGC5356 MGC5356 79025 hypothetical protein MGC5356 None Fibronectin, type III-like fold (IPR008957) high 9.34358533401 gnf1h08865_at MGC35206 MGC35206 339669 hypothetical protein MGC35206 None None high 9.3397660873 gnf1h06188_at PDCL2 GCPHLP;PDCL2 132954 phosducin-like 2 None Bipartite nuclear localization signal (IPR001472);Phosducin (IPR001200) high 9.33287430474 211597_s_at HOP Cameo;HOP;LAGY;MGC20820;NECC1;OB1;SMAP31;Toto 84525 homeodomain-only protein DNA binding (GO:0003677);transcription factor activity (GO:0003700) Homeobox (IPR001356);Homeodomain-like (IPR009057) high 9.3200047022 45653_at KCTD13 FKSG86;KCTD13;PDIP1;POLDIP1 253980 potassium channel tetramerisation domain containing 13 potassium ion transport (GO:0006813);protein binding (GO:0005515);voltage-gated potassium channel activity (GO:0005249) BTB/POZ (IPR000210);K+ channel tetramerisation (IPR003131) high 9.27301260278 208906_at BSCL2 BSCL2;GNG3LG;MGC4694;SEIPIN;SPG17 26580 Bernardinelli-Seip congenital lipodystrophy 2 (seipin) None Protein of unknown function DUF1226 (IPR009617) high 9.22325092449 gnf1h06145_at KLHL10 FLJ32662;KLHL10 317719 kelch-like 10 (Drosophila) DNA binding (GO:0003677);protein binding (GO:0005515) BTB/POZ (IPR000210);Myb DNA-binding domain (IPR001005) high 9.21464707474 221558_s_at LEF1 LEF1;TCF1ALPHA 51176 lymphoid enhancer-binding factor 1 DNA binding (GO:0003677);Wnt receptor signaling pathway (GO:0016055) HMG1/2 (high mobility group) box (IPR000910);Proline-rich region (IPR000694) high 9.17466901041 210031_at CD3Z CD3-ZETA;CD3H;CD3Q;CD3Z;TCRZ 919 CD3Z antigen, zeta polypeptide (TiT3 complex) T-cell receptor activity (GO:0004894);cell surface receptor linked signal transduction (GO:0007166);cellular defense response (GO:0006968);protein binding (GO:0005515);protein homodimerization activity (GO:0042803);receptor signaling protein activity (GO:0005057);transmembrane receptor activity (GO:0004888) Bipartite nuclear localization signal (IPR001472) high 9.13588455334 219820_at SLC6A16 NTT5;SLC6A16 28968 solute carrier family 6 (neurotransmitter transporter), member 16 neurotransmitter transport (GO:0006836);neurotransmitter transporter activity (GO:0005326);neurotransmitter:sodium symporter activity (GO:0005328);symport (GO:0015983);symporter activity (GO:0015293) Sodium:neurotransmitter symporter (IPR000175) high 9.13171887314 220003_at FLJ11004 FLJ11004 55282 hypothetical protein FLJ11004 None Bipartite nuclear localization signal (IPR001472) high 9.12749334197 203122_at TTC15 CGI-87;TTC15 51112 tetratricopeptide repeat domain 15 None TPR-like (IPR008941) high 9.11325311561 220299_at SPATA6 FLJ10007;SPATA6;SRF-1;SRF1 54558 spermatogenesis associated 6 None None high 9.08919020592 210171_s_at CREM CREM;ICER;MGC17881;MGC41893 1390 cAMP responsive element modulator DNA binding (GO:0003677);cAMP response element binding protein binding (GO:0008140);protein binding (GO:0005515);signal transduction (GO:0007165);transcription factor activity (GO:0003700) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Coactivator CBP, pKID (IPR003102);Eukaryotic transcription factor, DNA-binding (IPR008917);Fos transforming protein (IPR000837);cAMP response element binding (CREB) protein (IPR001630) high 9.08542848996 210115_at RPL39L RPL39L;RPL39L1 116832 ribosomal protein L39-like protein biosynthesis (GO:0006412);structural constituent of ribosome (GO:0003735) Ribosomal protein L39e (IPR000077) high 9.02071654289 gnf1h08170_at MGC33607 MGC33607 256309 hypothetical protein MGC33607 None Bipartite nuclear localization signal (IPR001472) high 9.01493561621 207961_x_at MYH11 MYH11;SMHC;SMMHC 4629 myosin, heavy polypeptide 11, smooth muscle ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);cell growth and/or maintenance (GO:0008151);motor activity (GO:0003774);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941) Bipartite nuclear localization signal (IPR001472);IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928) high 9.01284454484 gnf1h01130_at CAPZA3 CAPPA3;CAPZA3;Gsg3 93661 capping protein (actin filament) muscle Z-line, alpha 3 F-actin capping activity (GO:0003782);actin binding (GO:0003779);actin cytoskeleton organization and biogenesis (GO:0030036);structural constituent of cytoskeleton (GO:0005200) F-actin capping protein, alpha subunit (IPR002189) high 8.93278330195 207022_s_at LDHC LDH3;LDHC;LDHX 3948 lactate dehydrogenase C L-lactate dehydrogenase activity (GO:0004459);glycolysis (GO:0006096);oxidoreductase activity (GO:0016491) L-lactate dehydrogenase (IPR001557);Lactate/malate dehydrogenase (IPR001236) high 8.90091535025 213906_at MYBL1 AMYB;MYBL1 4603 v-myb myeloblastosis viral oncogene homolog (avian)-like 1 DNA binding (GO:0003677);transcriptional activator activity (GO:0016563) Myb DNA-binding domain (IPR001005) high 8.84240510498 gnf1h06040_at FLJ25410 FLJ25410 124404 hypothetical protein FLJ25410 GTP binding (GO:0005525) Cell division/GTP binding protein (IPR000038) high 8.84044062731 207019_s_at AKAP4 AKAP4;AKAP82;FSC1;hAKAP82;p82 8852 A kinase (PRKA) anchor protein 4 cell motility (GO:0006928);fertilization (sensu Animalia) (GO:0007338);protein kinase A anchoring activity (GO:0005079);protein kinase A binding (GO:0051018);signal transduction (GO:0007165);sperm motility (GO:0030317) A-kinase anchor 110 kDa (IPR008382) high 8.80038051757 221167_s_at DKFZP434K1172 DKFZP434K1172 83446 hypothetical protein DKFZp434K1172 None None high 8.78218505577 210352_at BRD8 BRD8;P120;SMAP;p120 10902 bromodomain containing 8 cell surface receptor linked signal transduction (GO:0007166);ligand-regulated transcription factor activity (GO:0003706);receptor activity (GO:0004872);signal transduction (GO:0007165);thyroid hormone receptor activity (GO:0004887);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700) Bipartite nuclear localization signal (IPR001472);Bromodomain (IPR001487) high 8.75966707332 220744_s_at WDR10 DKFZp434K016;FLJ00025;FLJ10897;FLJ11093;SPG;WDR10;WDR10p;WDR140 55764 WD repeat domain 10 None TPR-like (IPR008941) high 8.75359686715 205736_at PGAM2 PGAM2;PGAMM 5224 phosphoglycerate mutase 2 (muscle) bisphosphoglycerate phosphatase activity (GO:0004083);glycolysis (GO:0006096);hydrolase activity (GO:0016787);isomerase activity (GO:0016853);metabolism (GO:0008152);phosphoglycerate mutase activity (GO:0004619);striated muscle contraction (GO:0006941) Phosphoglycerate mutase 1 (IPR005952);Phosphoglycerate/bisphosphoglycerate mutase (IPR001345) low -9.81299939528 gnf1h08167_s_at gnf1h08167_s_at None None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) low -9.8926632476 209278_s_at TFPI2 PP5;TFPI-2;TFPI2 7980 tissue factor pathway inhibitor 2 blood coagulation (GO:0007596);extracellular matrix glycoprotein (GO:0005207);extracellular matrix structural constituent (GO:0005201);protease inhibitor activity (GO:0030414);serine-type endopeptidase inhibitor activity (GO:0004867) Protease inhibitor I2, Kunitz metazoa (IPR002223);Tissue factor pathway inhibitor (IPR008296) low -9.99410262392 204720_s_at DNAJC6 DJC6;DNAJC6;KIAA0473 9829 DnaJ (Hsp40) homolog, subfamily C, member 6 phosphoprotein phosphatase activity (GO:0004721);protein amino acid dephosphorylation (GO:0006470) Heat shock protein DnaJ, N-terminal (IPR001623);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) low -10.2209173145 211821_x_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) low -10.2247788993 204848_x_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) low -10.5044488809 gnf1h00293_at HEMGN EDAG;EDAG-1;HEMGN 55363 hemogen None Bipartite nuclear localization signal (IPR001472) low -10.8074466693 211560_s_at ALAS2 ALAS2;ANH1;ASB 212 aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) 5-aminolevulinate synthase activity (GO:0003870);acyltransferase activity (GO:0008415);biosynthesis (GO:0009058);heme biosynthesis (GO:0006783);transaminase activity (GO:0008483);transferase activity (GO:0016740) Aminolevulinic acid synthase (IPR003408);Aminotransferase, class I and II (IPR004839);Aminotransferase, class-II (IPR001917) low -10.8665148762 201830_s_at NET1 ARHGEF8;NET1;NET1A 10276 neuroepithelial cell transforming gene 1 guanyl-nucleotide exchange factor activity (GO:0005085);regulation of cell growth (GO:0001558);signal transduction (GO:0007165) DH domain (IPR000219);Pleckstrin-like (IPR001849) low -10.9907804163 201890_at RRM2 RRM2 6241 ribonucleotide reductase M2 polypeptide DNA replication (GO:0006260);deoxyribonucleoside diphosphate metabolism (GO:0009186);oxidoreductase activity (GO:0016491);ribonucleoside-diphosphate reductase activity (GO:0004748) Ferritin/ribonucleotide reductase-like (IPR009078);Ribonucleotide reductase (IPR000358) low -11.0563224256 207332_s_at TFRC CD71;TFR;TFRC;TRFR 7037 transferrin receptor (p90, CD71) endocytosis (GO:0006897);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);transferrin receptor activity (GO:0004998) Peptidase M28 (IPR007484);Protease-associated PA (IPR003137);Transferrin receptor-like dimerisation domain (IPR007365) low -11.1341899402 201110_s_at THBS1 THBS;THBS1;TSP;TSP1 7057 thrombospondin 1 blood coagulation (GO:0007596);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell motility (GO:0006928);development (GO:0007275);endopeptidase inhibitor activity (GO:0004866);heparin binding (GO:0008201);neurogenesis (GO:0007399);protein binding (GO:0005515);signal transducer activity (GO:0004871);structural molecule activity (GO:0005198) EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);Laminin G (IPR001791);Thrombospondin, C-terminal (IPR008859);Thrombospondin, N-terminal (IPR003129);Type I EGF (IPR006210);von Willebrand factor, type C (IPR001007) low -11.3690587245 208963_x_at FADS1 D5D;FADS1;FADSD5;LLCDL1;TU12 3992 fatty acid desaturase 1 C-5 sterol desaturase activity (GO:0000248);cell-cell signaling (GO:0007267);cellular response to starvation (GO:0009267);electron transport (GO:0006118);fatty acid desaturation (GO:0006636);icosanoid biosynthesis (GO:0046456);oxidoreductase activity (GO:0016491);phospholipid biosynthesis (GO:0008654);regulation of cell differentiation (GO:0045595) ARM repeat fold (IPR008938);Cytochrome b5 (IPR001199);Fatty acid desaturase (IPR005804);Fatty acid desaturase subdomain (IPR010257) low -11.4615776091 205837_s_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) low -12.2583856895 204475_at MMP1 CLG;CLGN;MMP1 4312 matrix metalloproteinase 1 (interstitial collagenase) calcium ion binding (GO:0005509);collagen catabolism (GO:0030574);collagenase activity (GO:0008133);hydrolase activity (GO:0016787);interstitial collagenase activity (GO:0004232);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) Hemopexin (IPR000585);Peptidase M10A and M12B, matrixin and adamalysin (IPR001818);Peptidase, metallopeptidases (IPR006026) low -13.6241417191 216609_at TXN TRX;TXN 7295 thioredoxin antimicrobial humoral response (sensu Protostomia) (GO:0006960);cell motility (GO:0006928);cell proliferation (GO:0008283);cell-cell signaling (GO:0007267);electron transport (GO:0006118);electron transporter activity (GO:0005489);signal transduction (GO:0007165);thiol-disulfide exchange intermediate activity (GO:0030508);thioredoxin (GO:0000008) Thioredoxin domain 2 (IPR006663);Thioredoxin type domain (IPR006662)