PC-107 p<0.000010 High/Low PC-107 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 4.04640792448 216819_at 216819_at None None Human DNA sequence from clone RP5-871G17 on chromosome 1. Contains ESTs, STSs and GSSs. Contains the HAO2 gene for hydroxyacid oxidase 2 (long chain), the HSD3B2 gene for hydroxy-delta-5-steroid dehydrogenase (3 beta-and steroid delta-isomerase 2), two GA None None high 3.82610123923 gnf1h07739_at HMGCLL1 DKFZP434G1411;HMGCLL1;bA418P12.1 54511 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 catalytic activity (GO:0003824) HMG-CoA lyase-like (IPR000891) high 3.64296401814 207078_at MED6 MED6;NY-REN-28 10001 mediator of RNA polymerase II transcription, subunit 6 homolog (yeast) RNA polymerase II transcription factor activity (GO:0003702);receptor activity (GO:0004872);transcription regulator activity (GO:0030528) MED6 mediator (IPR007018) high 3.64079953485 gnf1h06538_at gnf1h06538_at None None None None None high 3.59458334008 214592_s_at SNAPC5 SNAP19;SNAPC5 10302 small nuclear RNA activating complex, polypeptide 5, 19kDa transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) None high 3.43193023568 gnf1h07548_at C10orf30 C10orf30;FLJ40283 222389 chromosome 10 open reading frame 30 None Protein of unknown function DUF1172 (IPR009552) high 3.42154604068 204315_s_at GTSE1 B99;GTSE-1;GTSE1 51512 G-2 and S-phase expressed 1 microtubule-based process (GO:0007017);molecular_function unknown (GO:0005554) None high 3.41365767868 205732_s_at NCOA2 GRIP1;NCOA2;NCoA-2;TIF2 10499 nuclear receptor coactivator 2 signal transducer activity (GO:0004871);signal transduction (GO:0007165);transcription coactivator activity (GO:0003713);translation regulator activity (GO:0045182) Basic helix-loop-helix dimerization domain bHLH (IPR001092);Calcium-binding EF-hand (IPR002048);Nuclear receptor coactivator Src-1 (IPR008955);PAS (IPR000014) high 3.38351863993 217507_at SLC11A1 LSH;NRAMP;NRAMP1;SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 immune response (GO:0006955);iron ion transport (GO:0006826);response to bacteria (GO:0009617);response to pest/pathogen/parasite (GO:0009613);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215) Natural resistance-associated macrophage protein (IPR001046) high 3.37584932481 210196_s_at PSG1 B1G1;CD66f;PBG1;PSBG1;PSG1;PSGGA;SP1 5669 pregnancy specific beta-1-glycoprotein 1 plasma glycoprotein (GO:0005211);pregnancy (GO:0007565) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin-like (IPR007110) high 3.35484281494 gnf1h02711_s_at gnf1h02711_s_at None None None None None high 3.34334629135 gnf1h03206_at ANKRD30A ANKRD30A;NY-BR-1 91074 ankyrin repeat domain 30A aspartic-type endopeptidase activity (GO:0004190);protein binding (GO:0005515);proteolysis and peptidolysis (GO:0006508);transcription factor activity (GO:0003700) None high 3.33271412594 216613_at AL050042 None None None None None high 3.30780892623 gnf1h04554_at gnf1h04554_at None None None None None high 3.30112878799 206864_s_at HRK DP5;HARAKIRI;HRK 8739 harakiri, BCL2 interacting protein (contains only BH3 domain) apoptosis (GO:0006915);apoptosis regulator activity (GO:0016329) Apoptosis regulator Bcl-2 protein, BH (IPR000712) high 3.26443537896 220513_at C6orf148 C6orf148;MGC10818;bA257K9.4 80759 chromosome 6 open reading frame 148 None None high 3.22689375091 gnf1h07744_s_at GHR GHR 2690 growth hormone receptor endocytosis (GO:0006897);growth hormone receptor activity (GO:0004903);growth pattern (GO:0007150);receptor activity (GO:0004872);skeletal development (GO:0001501) Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Long hematopoietin receptor, single chain (IPR003528) high 3.21299252206 214562_at HIST1H4L H4.k;H4/k;H4FK;HIST1H4L 8368 histone 1, H4l None Histone H4 (IPR001951) low -3.75328265954 204463_s_at EDNRA EDNRA;ETA;ETRA 1909 endothelin receptor type A G-protein coupled receptor protein signaling pathway (GO:0007186);cell proliferation (GO:0008283);endothelin receptor activity (GO:0004962);phosphatidylinositol-4,5-bisphosphate hydrolysis (GO:0007203);phosphoinositide phospholipase C activity (GO:0004435);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584);signal transduction (GO:0007165);smooth muscle contraction (GO:0006939) Endothelin A receptor (IPR002175);Endothelin receptor (IPR000499);Rhodopsin-like GPCR superfamily (IPR000276) low -3.77595619179 215542_at 215542_at None None None None None low -3.77860935699 211265_at PTGER3 EP3;MGC27302;PTGER3 5733 prostaglandin E receptor 3 (subtype EP3) G-protein coupled receptor protein signaling pathway (GO:0007186);cell death (GO:0008219);ligand-dependent nuclear receptor activity (GO:0004879);prostaglandin E receptor activity (GO:0004957);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584);transcription, DNA-dependent (GO:0006351) Bipartite nuclear localization signal (IPR001472);Prostaglandin receptor (IPR001244);Prostanoid EP3 receptor (IPR000265);Prostanoid EP3 receptor, type 2 (IPR001481);Prostanoid receptor (IPR008365);Rhodopsin-like GPCR superfamily (IPR000276);Thromboxane receptor (IPR001105) low -3.82497728155 gnf1h04324_at ARHGAP10 ARHGAP10;FLJ20896;FLJ41791;GRAF2 79658 Rho GTPase activating protein 10 None Immunoglobulin/major histocompatibility complex (IPR003006);Pleckstrin-like (IPR001849);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198);SH3 (IPR001452) low -3.82702324878 gnf1h09676_s_at gnf1h09676_s_at None None None None None low -3.84020794007 AFFX-r2-Bs-dap-3_at AFFX-r2-Bs-dap-3_at None None L38424 B subtilis dapB, jojF, jojG genes corresponding to nucleotides 1358-3197 of L38424 (-5, -M, -3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None low -3.86017356577 216494_at 216494_at None None Human DNA sequence from clone 497J21 on chromosome 6q26-27. Contains a KOC (KH-domain containg transcript overexpressed in cancer) pseudogene, genomic marker D6S193, ESTs, STSs and GSSs, and a ca repeat polymorphism None None low -3.86220113528 220432_s_at CYP39A1 CYP39A1 51302 cytochrome P450, family 39, subfamily A, polypeptide 1 bile acid biosynthesis (GO:0006699);bile acid catabolism (GO:0030573);digestion (GO:0007586);electron transport (GO:0006118);electron transporter activity (GO:0005489);monooxygenase activity (GO:0004497);oxysterol 7-alpha-hydroxylase activity (GO:0008396) B-class P450 (IPR002397);Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) low -3.89669130557 gnf1h01208_at GBP5 GBP5 115362 guanylate binding protein 5 GTP binding (GO:0005525);GTPase activity (GO:0003924);immune response (GO:0006955) Guanylate-binding protein (IPR003191) low -3.92698721672 gnf1h10927_at gnf1h10927_at None None None None Olfactory receptor (IPR000725);Rhodopsin-like GPCR superfamily (IPR000276) low -3.93101791312 216893_s_at COL4A3 COL4A3;TUMSTATIN 1285 collagen, type IV, alpha 3 (Goodpasture antigen) DNA binding (GO:0003677);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell proliferation (GO:0008283);cell surface receptor linked signal transduction (GO:0007166);circulation (GO:0008015);collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);integrin binding (GO:0005178);metalloendopeptidase inhibitor activity (GO:0008191);negative regulation of cell proliferation (GO:0008285);pathogenesis (GO:0009405);perception of sound (GO:0007605);phosphate transport (GO:0006817);protein binding (GO:0005515);structural molecule activity (GO:0005198);tumor suppressor (GO:0008181) Proline-rich region (IPR000694);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) low -3.9811902808 gnf1h00324_at DMAP1 DMAP1;DNMAP1;DNMTAP1;FLJ11543;KIAA1425 55929 DNA methyltransferase 1 associated protein 1 DNA binding (GO:0003677);DNA methylation (GO:0006306);transcriptional repressor activity (GO:0016564) Bipartite nuclear localization signal (IPR001472);DNA methyltransferase 1-associated 1 (IPR008468);Myb DNA-binding domain (IPR001005) low -4.24817416109 gnf1h08151_s_at gnf1h08151_s_at None None None None None low -5.5958763756 210729_at NPY2R NPY2R 4887 neuropeptide Y receptor Y2 G-protein coupled receptor protein signaling pathway (GO:0007186);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);calcium channel regulator activity (GO:0005246);circadian rhythm (GO:0007623);feeding behavior (GO:0007631);locomotory behavior (GO:0007626);neuropeptide Y receptor activity (GO:0004983);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584) Legume lectin, beta domain (IPR001220);Neuropeptide Y receptor (IPR000611);Neuropeptide Y2 receptor (IPR001358);Rhodopsin-like GPCR superfamily (IPR000276)