PC-109 p<0.000010 High/Low PC-109 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 4.18796998049 211109_at JAK3 JAK3;JAKL;LJAK 3718 Janus kinase 3 (a protein tyrosine kinase, leukocyte) ATP binding (GO:0005524);Janus kinase activity (GO:0004718);cell growth and/or maintenance (GO:0008151);intracellular signaling cascade (GO:0007242);kinase activity (GO:0016301);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Band 4.1 (IPR000299);FERM (IPR009065);Janus kinase 3, JAK3 (IPR009130);Janus kinase, JAK (IPR009127);Peptidase, eukaryotic cysteine peptidase active site (IPR000169);Protein kinase (IPR000719);SH2 motif (IPR000980);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 4.13698001302 202015_x_at METAP2 METAP2;MNPEP;p67 10988 methionyl aminopeptidase 2 hydrolase activity (GO:0016787);methionyl aminopeptidase activity (GO:0004239);protein modification (GO:0006464);proteolysis and peptidolysis (GO:0006508) Peptidase M24 (IPR000994);Peptidase M24, methionine aminopeptidase (IPR001714);Peptidase M24A, methionine aminopeptidase, subfamily 2 (IPR002468);Winged helix DNA-binding (IPR009058) high 3.96294870196 206659_at FLJ14082 FLJ14082 80092 hypothetical protein FLJ14082 None None high 3.80395735138 220448_at KCNK12 KCNK12;THIK-2;THIK2 56660 potassium channel, subfamily K, member 12 ion transport (GO:0006811);potassium channel activity (GO:0005267);potassium ion transport (GO:0006813);voltage-gated ion channel activity (GO:0005244) K+ channel, pore region (IPR001622);K+ channel, two pore (IPR003280);THIK K+ channel (IPR005410) high 3.76230696195 gnf1h03944_x_at gnf1h03944_x_at None None None None None high 3.64726157058 gnf1h04354_at WDR17 WDR17 116966 WD repeat domain 17 None None high 3.57151284097 206982_at CRYBA1 CRYB1;CRYBA1 1411 crystallin, beta A1 structural constituent of eye lens (GO:0005212);visual perception (GO:0007601) Beta and gamma crystallin (IPR001064) high 3.52943977137 gnf1h07832_at gnf1h07832_at None None None None None high 3.47479002553 220888_s_at C20orf32 C20orf32;HEFL 57091 chromosome 20 open reading frame 32 signal transduction (GO:0007165);two-component sensor molecule activity (GO:0000155) Proline-rich region (IPR000694);SH3 (IPR001452) high 3.45745473645 207256_at MBL2 COLEC1;MBL;MBL2;MBP;MBP1 4153 mannose-binding lectin (protein C) 2, soluble (opsonic defect) antigen binding (GO:0003823);defense/immunity protein activity (GO:0003793);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);lectin (GO:0005530);mannose binding (GO:0005537);mannose binding lectin (GO:0005532);opsonin activity (GO:0008229);phosphate transport (GO:0006817);sugar binding (GO:0005529) C-type lectin (IPR001304) high 3.44133834686 207406_at CYP7A1 CP7A;CYP7;CYP7A1 1581 cytochrome P450, family 7, subfamily A, polypeptide 1 bile acid biosynthesis (GO:0006699);cholesterol 7-alpha-monooxygenase activity (GO:0008123);cholesterol metabolism (GO:0008203);electron transport (GO:0006118);monooxygenase activity (GO:0004497) Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) high 3.43894643756 205848_at GAS2 GAS2;MGC32610 2620 growth arrest-specific 2 apoptosis (GO:0006915);cell growth and/or maintenance (GO:0008151);cellular morphogenesis (GO:0000902) Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);Growth-arrest-specific protein 2 (IPR003108) high 3.38021429312 gnf1h04983_at FGFR1 BFGFR;C-FGR;CEK;FGFR1;FLG;FLT2;KAL2;N-SAM 2260 fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) ATP binding (GO:0005524);MAPKKK cascade (GO:0000165);cell growth (GO:0016049);fibroblast growth factor receptor activity (GO:0005007);fibroblast growth factor receptor signaling pathway (GO:0008543);heparin binding (GO:0008201);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor activity (GO:0004872);skeletal development (GO:0001501);transferase activity (GO:0016740) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -3.55252219627 217091_at X86400 None None None None None low -3.58854547506 207349_s_at UCP3 SLC25A9;UCP3 7352 uncoupling protein 3 (mitochondrial, proton carrier) binding (GO:0005488);energy pathways (GO:0006091);lipid metabolism (GO:0006629);mitochondrial transport (GO:0006839);proton transport (GO:0015992);respiratory gaseous exchange (GO:0007585);transport (GO:0006810);transporter activity (GO:0005215);uncoupling protein activity (GO:0015302) Adenine nucleotide translocator 1 (IPR002113);Mitochondrial brown fat uncoupling protein (IPR002030);Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993) low -3.59638145745 220735_s_at SENP7 KIAA1707;SENP7 57337 SUMO1/sentrin specific protease 7 cysteine-type peptidase activity (GO:0008234);protein sumoylation (GO:0016925);proteolysis and peptidolysis (GO:0006508) Peptidase C48, SUMO/Sentrin/Ubl1 (IPR003653) low -3.60721696998 gnf1h04713_at gnf1h04713_at None None None None None low -3.61534114141 207120_at FLJ14011 FLJ14011 63934 hypothetical zinc finger protein FLJ14011 nucleic acid binding (GO:0003676);zinc ion binding (GO:0008270) Bipartite nuclear localization signal (IPR001472);KRAB box (IPR001909);TonB-dependent receptor (IPR000531);Zn-finger, C2H2 subtype (IPR007086);Zn-finger, C2H2 type (IPR007087) low -3.65406787999 211470_s_at SULT1C1 ST1C1;ST1C2;SULT1C#1;SULT1C1;humSULTC2 6819 sulfotransferase family, cytosolic, 1C, member 1 amine metabolism (GO:0009308);sulfotransferase activity (GO:0008146);transferase activity (GO:0016740) Sulfotransferase (IPR000863) low -3.6882280515 219973_at FLJ23548 FLJ23548 79642 hypothetical protein FLJ23548 None Bipartite nuclear localization signal (IPR001472);Sulfatase (IPR000917) low -3.69370823034 207647_at CDY1 CDY;CDY1 9085 chromodomain protein, Y-linked, 1 chromatin assembly/disassembly (GO:0006333);chromatin binding (GO:0003682);spermatogenesis (GO:0007283) Chromo (IPR000953);Enoyl-CoA hydratase/isomerase (IPR001753) low -3.71042007774 220004_at DDX43 DDX43;DKFZp434H2114;HAGE 55510 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 ATP binding (GO:0005524);ATP-dependent RNA helicase activity (GO:0004004);RNA binding (GO:0003723);hydrolase activity (GO:0016787) ATP-dependent helicase, DEAD-box (IPR000629);Bipartite nuclear localization signal (IPR001472);DEAD/DEAH box helicase (IPR001410);Helicase, C-terminal (IPR001650);KH (IPR004087);KH, type 1 (IPR004088) low -3.71432588658 gnf1h04355_x_at WDR17 WDR17 116966 WD repeat domain 17 None None low -3.84444030019 214590_s_at UBE2D1 E2(17)KB1;SFT;UBC4/5;UBCH5;UBCH5A;UBE2D1 7321 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) ligase activity (GO:0016874);protein modification (GO:0006464);ubiquitin conjugating enzyme activity (GO:0004840);ubiquitin cycle (GO:0006512);ubiquitin-dependent protein catabolism (GO:0006511);ubiquitin-protein ligase activity (GO:0004842) Ubiquitin-conjugating enzymes (IPR000608) low -3.91868627006 210163_at CXCL11 CXCL11;H174;I-TAC;IP-9;IP9;SCYB11;SCYB9B;b-R1 6373 chemokine (C-X-C motif) ligand 11 cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);immune response (GO:0006955);inflammatory response (GO:0006954);response to pathogenic fungi (GO:0009621);signal transduction (GO:0007165) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, interleukin-8 like (IPR001811) low -3.95689146826 216626_at AL050026 None None None None None low -4.20720800552 gnf1h00150_at PRO0767 None None PRO0767 protein None None low -4.37867738069 214660_at ITGA1 CD49a;ITGA1;VLA1 3672 integrin, alpha 1 cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);collagen binding (GO:0005518);integrin-mediated signaling pathway (GO:0007229);magnesium ion binding (GO:0000287);receptor activity (GO:0004872) Beta-lactamase, class A (IPR000871);Bipartite nuclear localization signal (IPR001472);Integrins alpha chain (IPR000413);von Willebrand factor, type A (IPR002035) low -4.52866497838 222382_x_at NUP205 C7orf14;KIAA0225;NUP205 23165 nucleoporin 205kDa transport (GO:0006810) None low -5.09809401992 gnf1h00846_at CAPS2 CAPS2 84698 calcyphosphine 2 calcium ion binding (GO:0005509) Calcium-binding EF-hand (IPR002048)