PC-138 p<0.000010 High/Low PC-138 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 3.86555524621 gnf1h10452_at ZNF490 KIAA1198;ZNF490 57474 zinc finger protein 490 DNA binding (GO:0003677);zinc ion binding (GO:0008270) KRAB box (IPR001909);Zn-finger, C2H2 subtype (IPR007086);Zn-finger, C2H2 type (IPR007087) high 3.79536988694 213663_s_at FLJ20152 FLJ20152 54463 hypothetical protein FLJ20152 None None high 3.77500683638 gnf1h09420_at gnf1h09420_at None None None None None high 3.76269130404 205841_at JAK2 JAK2 3717 Janus kinase 2 (a protein tyrosine kinase) ATP binding (GO:0005524);JAK-STAT cascade (GO:0007259);Janus kinase activity (GO:0004718);SH2 domain binding (GO:0042169);cell growth and/or maintenance (GO:0008151);cell motility (GO:0006928);intracellular signaling cascade (GO:0007242);mesoderm development (GO:0007498);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Band 4.1 (IPR000299);FERM (IPR009065);Janus kinase 2, JAK2 (IPR009129);Janus kinase, JAK (IPR009127);Protein kinase (IPR000719);SH2 motif (IPR000980);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 3.6592871473 210456_at PCYT1B CCT-beta;CTB;PCYT1B 9468 phosphate cytidylyltransferase 1, choline, beta isoform biosynthesis (GO:0009058);choline-phosphate cytidylyltransferase activity (GO:0004105);defense response (GO:0006952);nucleotidyltransferase activity (GO:0016779);phosphatidylcholine biosynthesis (GO:0006656);phospholipid biosynthesis (GO:0008654);transferase activity (GO:0016740) Bipartite nuclear localization signal (IPR001472);Cytidyltransferase-related domain (IPR004821);Cytidylyltransferase (IPR004820);Lipoprotein, type 6 (IPR001800) high 3.64589586684 gnf1h03671_at gnf1h03671_at None None None None None high 3.61280351225 219996_at ASB7 ASB7;FLJ22551 140460 ankyrin repeat and SOCS box-containing 7 intracellular signaling cascade (GO:0007242) SOCS protein, C-terminal (IPR001496) high 3.59872187544 218457_s_at DNMT3A DNMT3A;DNMT3A2;M.HsaIIIA 1788 DNA (cytosine-5-)-methyltransferase 3 alpha DNA (cytosine-5-)-methyltransferase activity (GO:0003886);DNA binding (GO:0003677);DNA methylation (GO:0006306);imprinting (GO:0006349);methyltransferase activity (GO:0008168);transferase activity (GO:0016740) C-5 cytosine-specific DNA methylase (IPR001525);PWWP domain (IPR000313) high 3.57988291416 gnf1h02848_at EML5 EMAP-2;EML5;HuEMAP-2 161436 echinoderm microtubule associated protein like 5 None None high 3.57460319146 207465_at PRO0628 PRO0628 29053 PRO0628 protein None None high 3.54638302516 gnf1h09235_at gnf1h09235_at None None None None None high 3.52168278093 gnf1h03207_x_at ANKRD30A ANKRD30A;NY-BR-1 91074 ankyrin repeat domain 30A aspartic-type endopeptidase activity (GO:0004190);protein binding (GO:0005515);proteolysis and peptidolysis (GO:0006508);transcription factor activity (GO:0003700) None high 3.4604868916 208343_s_at NR5A2 B1F;B1F2;CPF;FTF;FTZ-F1;FTZ-F1beta;HB1F;LRH-1;NR5A2;hB1F;hB1F-2 2494 nuclear receptor subfamily 5, group A, member 2 RNA polymerase II transcription factor activity, enhancer binding (GO:0003705);embryogenesis and morphogenesis (GO:0007345);morphogenesis (GO:0009653);pathogenesis (GO:0009405);receptor activity (GO:0004872);steroid hormone receptor activity (GO:0003707);transcription (GO:0006350);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) Ligand-binding domain of nuclear hormone receptor (IPR000536);Steroid hormone receptor (IPR001723);Steroid nuclear receptor, ligand-binding (IPR008946);Vitamin D receptor (IPR000324);Zn-finger, C4-type steroid receptor (IPR001628) high 3.43477142214 gnf1h01504_x_at gnf1h01504_x_at None None None None None high 3.4083712653 216839_at LAMA2 LAMA2;LAMM 3908 laminin, alpha 2 (merosin, congenital muscular dystrophy) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);muscle development (GO:0007517);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Galactose-binding like (IPR008979);Laminin B (IPR000034);Laminin G (IPR001791);Laminin, N-terminal (IPR008211);Laminin-type EGF-like domain (IPR002049) high 3.39872924207 gnf1h09377_at gnf1h09377_at None None None None Ribosomal protein L24E (IPR000988) high 3.39827479837 gnf1h01489_at PF6 FLJ34497;PF6 200162 projection protein PF6 None RNA polymerase, RBP11-like (IPR009025) high 3.36344383425 gnf1h02850_at gnf1h02850_at None None None None None high 3.35855666787 202987_at C6orf4 ACT1;C6orf4;C6orf5;C6orf6;CIKS;DKFZP586G0522;MGC3581 10758 chromosome 6 open reading frame 4 intracellular signaling cascade (GO:0007242);molecular_function unknown (GO:0005554);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871) Proline-rich region (IPR000694) high 3.34266000608 gnf1h04959_x_at gnf1h04959_x_at None None None None None high 3.32860259609 206977_at PTH PTH 5741 parathyroid hormone G-protein coupled receptor protein signaling pathway (GO:0007186);cAMP generating peptide activity (GO:0008492);cAMP metabolism (GO:0046058);calcium ion homeostasis (GO:0006874);cell-cell signaling (GO:0007267);hormone activity (GO:0005179);peptide hormone (GO:0005180);skeletal development (GO:0001501) Parathyroid hormone (IPR001415);Parathyroid hormone subtype (IPR003625) high 3.31242995199 203715_at TBCE HRD;KCS;KCS1;TBCE;pac2 6905 tubulin-specific chaperone e beta-tubulin folding (GO:0007025);co-chaperonin activity (GO:0003772) CAP-Gly domain (IPR000938) low -3.12916888842 gnf1h05388_at gnf1h05388_at None None None None None low -3.17845856641 gnf1h05320_at gnf1h05320_at None None None None None low -3.18172066125 gnf1h10068_x_at gnf1h10068_x_at None None None None None low -3.18640360927 gnf1h03240_s_at TTYH2 MGC4837;TTYH2 94015 tweety homolog 2 (Drosophila) None Bipartite nuclear localization signal (IPR001472);Tweety (IPR006990) low -3.27455831695 gnf1h07879_at gnf1h07879_at None None None None None low -3.31836571063 gnf1h04921_at gnf1h04921_at None None None None None low -3.32477815996 213764_s_at MFAP5 MAGP2;MFAP5;MP25 8076 microfibrillar associated protein 5 extracellular matrix structural constituent (GO:0005201) Microfibril-associated glycoprotein (IPR008673) low -3.34772511179 206652_at 206652_at None None None None None low -3.37562883754 220503_at SLC13A1 NAS1;NaSi-1;SLC13A1 6561 solute carrier family 13 (sodium/sulfate symporters), member 1 sodium ion transport (GO:0006814);sulfate transport (GO:0008272);symport (GO:0015983);symporter activity (GO:0015293);transport (GO:0006810);transporter activity (GO:0005215) Sodium/sulphate symporter (IPR001898) low -3.43416745991 219990_at FLJ23311 FLJ23311 79733 FLJ23311 protein None Bipartite nuclear localization signal (IPR001472) low -3.44191955572 204737_s_at MYH7 CMH1;MYH7;MYHCB 4625 myosin, heavy polypeptide 7, cardiac muscle, beta ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);microfilament motor activity (GO:0000146);motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928);Tropomyosin (IPR000533) low -3.49868965014 206157_at PTX3 PTX3;TSG-14 5806 pentaxin-related gene, rapidly induced by IL-1 beta inflammatory response (GO:0006954) Concanavalin A-like lectin/glucanase (IPR008985);Pentaxin (IPR001759) low -3.59600348794 215332_s_at CD8B1 CD8B;CD8B1;LYT3;Leu2;Ly3 926 CD8 antigen, beta polypeptide 1 (p37) MHC class I protein binding (GO:0042288);T-cell activation (GO:0042110);coreceptor activity (GO:0015026);immune response (GO:0006955);protein binding (GO:0005515);transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -3.62401185927 gnf1h03862_s_at gnf1h03862_s_at None None None None None low -3.77416192269 215351_at RTCD1 RPC;RTCD1 8634 RNA terminal phosphate cyclase domain 1 RNA binding (GO:0003723);RNA-3'-phosphate cyclase activity (GO:0003963);ligase activity (GO:0016874) RNA 3'-terminal phosphate cyclase (IPR000228) low -3.82968278847 gnf1h08694_at gnf1h08694_at None None None None None low -3.87754887139 217440_at AL049342 None None None None None low -3.90304392341 gnf1h02612_at gnf1h02612_at None None None None None low -4.54335840627 219552_at POLYDOM FLJ13529;FLJ90754;POLYDOM 79987 likely ortholog of mouse polydom None Hyalin (IPR003410);Sushi domain/SCR domain/CCP module (IPR000436)