PC-149 p<0.000010 High/Low PC-149 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 3.88180749752 206291_at NTS NMN-125;NT/N;NTS;NTS1 4922 neurotensin neuropeptide hormone activity (GO:0005184);peptide hormone (GO:0005180);signal transduction (GO:0007165) Neurotensin/neuromedin N (IPR008055) high 3.84841107736 204727_at WDHD1 AND-1;WDHD1 11169 WD repeat and HMG-box DNA binding protein 1 DNA binding (GO:0003677) HMG1/2 (high mobility group) box (IPR000910) high 3.48862232924 207342_at CNGB1 CNCG2;CNCG3L;CNGB1;GAR1;GARP;RCNC2;RCNCb;RCNCbeta 1258 cyclic nucleotide gated channel beta 1 3',5'-cAMP binding (GO:0030552);intracellular cAMP activated cation channel activity (GO:0005222);ion channel activity (GO:0005216);ion transport (GO:0006811);ligand-gated ion channel activity (GO:0015276);potassium channel activity (GO:0005267);potassium ion transport (GO:0006813);small molecule transport (GO:0006832);transport (GO:0006810);visual perception (GO:0007601) Cyclic nucleotide-binding domain (IPR000595);Ion transport protein (IPR005821);K+ channel, pore region (IPR001622);Proline-rich region (IPR000694) high 3.45786365382 211369_at CHP CHP;SLC9A1BP 11261 calcium binding protein P22 calcium ion binding (GO:0005509);potassium channel regulator activity (GO:0015459);potassium ion transport (GO:0006813);small GTPase mediated signal transduction (GO:0007264) Calcium-binding EF-hand (IPR002048) high 3.45392606499 211315_s_at CACNA1G CACNA1G;Ca(V)T.1;NBR13 8913 calcium channel, voltage-dependent, alpha 1G subunit calcium ion binding (GO:0005509);calcium ion transport (GO:0006816);cation transport (GO:0006812);low voltage-gated calcium channel activity (GO:0008332);small molecule transport (GO:0006832);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Ca2+ channel, alpha subunit (IPR002077);Ca2+/Na+ channel, pore region (IPR001682);Cation (not K+) channel, TM region (IPR002111);Cation channel, non-ligand gated (IPR005820);Ion transport protein (IPR005821);T-type voltage-dependent calcium channel alpha 1 subunit (IPR005445) high 3.42836255335 gnf1h03155_at gnf1h03155_at None None None None None high 3.36374353988 gnf1h03183_x_at gnf1h03183_x_at None None None None None high 3.3600248043 214524_at GHRH GHRF;GHRH;GRF 2691 growth hormone releasing hormone G-protein signaling\, coupled to cAMP nucleotide second messenger (GO:0007188);cell-cell signaling (GO:0007267);hormone activity (GO:0005179);receptor binding (GO:0005102);signal transduction (GO:0007165) None high 3.24519458256 217547_x_at TIZ TBZF;TIZ 171392 TRAF6-inhibitory zinc finger protein DNA binding (GO:0003677);I-kappaB kinase/NF-kappaB cascade (GO:0007249);cytokine and chemokine mediated signaling pathway (GO:0019221);hemopoiesis (GO:0030097);negative regulation of osteoclast differentiation (GO:0045671);negative regulation of protein kinase activity (GO:0006469);nucleic acid binding (GO:0003676);protein binding (GO:0005515);transcriptional repressor activity (GO:0016564);zinc ion binding (GO:0008270) KRAB box (IPR001909);Zn-finger, C2H2 subtype (IPR007086);Zn-finger, C2H2 type (IPR007087) high 3.21133302119 AFFX-LysX-5_at AFFX-LysX-5_at None None X17013 B subtilis lys gene for diaminopimelate decarboxylase corresponding to nucleotides 350-1345 of X17013 (-5, -M, -3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 3.18998197927 217110_s_at MUC4 HSA276359;MUC4 4585 mucin 4, tracheobronchial ErbB-2 class receptor binding (GO:0005176);cell-matrix adhesion (GO:0007160);extracellular matrix constituent, lubricant activity (GO:0030197);extracellular matrix structural constituent (GO:0005201) AMOP domain (IPR005533);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);NIDO (IPR010362);Nidogen, extracellular region (IPR003886);Sugar transporter superfamily (IPR005829);Type I EGF (IPR006210);Whey acidic protein, core region (IPR008197);von Willebrand factor, type D (IPR001846) high 3.189955821 gnf1h07798_at FLJ13273 FLJ13273 79807 hypothetical protein FLJ13273 S-adenosylmethionine-dependent methyltransferase activity (GO:0008757) Bipartite nuclear localization signal (IPR001472);Glutathione S-transferase, C-terminal (IPR004046);SAM (and some other nucleotide) binding motif (IPR000051) high 3.17896708494 210626_at AKAP1 AKAP;AKAP1;AKAP121;AKAP149;AKAP84;D-AKAP1;MGC1807;PRKA1;SAKAP84 8165 A kinase (PRKA) anchor protein 1 RNA binding (GO:0003723);protein kinase A anchoring activity (GO:0005079) KH (IPR004087);KH, type 1 (IPR004088);Maternal tudor protein (IPR008191);Tudor domain (IPR002999) high 3.17772295498 gnf1h01935_x_at gnf1h01935_x_at None None None None None high 3.16117945615 32088_at BLZF1 BLZF1;GOLGIN-45;JEM-1;JEM1;MGC22497 8548 basic leucine zipper nuclear factor 1 (JEM-1) RNA polymerase II transcription factor activity (GO:0003702);biological_process unknown (GO:0000004);cell proliferation (GO:0008283);molecular_function unknown (GO:0005554);regulation of cell growth (GO:0001558);transcription factor activity (GO:0003700) None high 3.14757893009 gnf1h04934_at FLJ23749 FLJ23749 91694 hypothetical protein FLJ23749 ATP-dependent peptidase activity (GO:0004176);ATP-dependent proteolysis (GO:0006510) Homeodomain-like (IPR009057);Peptidase S16, lon N-terminal (IPR003111);Zn-finger, RING (IPR001841) high 3.13549328117 210258_at RGS13 MGC17173;RGS13 6003 regulator of G-protein signalling 13 signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) high 3.13023679586 222285_at IGHM IGHM 3507 immunoglobulin heavy constant mu antigen binding (GO:0003823);immune response (GO:0006955) Helix-turn-helix, AraC type (IPR000005);Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 3.12634177812 207928_s_at GLRA3 GLRA3 8001 glycine receptor, alpha 3 GABA-A receptor activity (GO:0004890);chloride transport (GO:0006821);extracellular ligand-gated ion channel activity (GO:0005230);glycine binding (GO:0016594);glycine-gated chloride channel activity (GO:0016934);ion channel activity (GO:0005216);ion transport (GO:0006811);neurotransmitter receptor activity (GO:0030594) Glycine receptor alpha (IPR008127);Glycine receptor alpha3 (IPR008130);Neurotransmitter-gated ion-channel (IPR006201);Neurotransmitter-gated ion-channel ligand binding domain (IPR006202);Neurotransmitter-gated ion-channel transmembrane region (IPR006029) high 3.12525345245 217505_at BG403790 None None None None None high 3.10772639358 205728_at ODZ1 ODZ1;ODZ3;TEN-M1;TNM;TNM1 10178 odz, odd Oz/ten-m homolog 1(Drosophila) heparin binding (GO:0008201);immune response (GO:0006955);negative regulation of cell proliferation (GO:0008285);neurogenesis (GO:0007399);proteolysis and peptidolysis (GO:0006508);subtilase activity (GO:0004289) Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Laminin-type EGF-like domain (IPR002049);Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209);Teneurin intracellular, N-terminal (IPR009471);Type I EGF (IPR006210) high 3.09971906144 222196_at AK000470 None None None None None low -2.89635870127 gnf1h02637_x_at VTI1A MVti1;VTI1A;Vti1-rp2 143187 vesicle transport through interaction with t-SNAREs homolog 1A (yeast) intracellular protein transport (GO:0006886);protein transport (GO:0015031);protein transporter activity (GO:0008565);vesicle-mediated transport (GO:0016192) Target SNARE coiled-coil domain (IPR000727);Vesicle transport v-SNARE (IPR007705) low -2.89992149038 211116_at SLC9A2 NHE2;SLC9A2 6549 solute carrier family 9 (sodium/hydrogen exchanger), isoform 2 antiport (GO:0015982);antiporter activity (GO:0015297);ion channel activity (GO:0005216);regulation of pH (GO:0006885);sodium ion transport (GO:0006814);sodium:hydrogen antiporter activity (GO:0015385);solute:hydrogen antiporter activity (GO:0015299);transport (GO:0006810) Na+/H+ exchanger, isoform 2 (NHE2) (IPR001953);Sodium/hydrogen exchanger (IPR006153);Sodium/hydrogen exchanger subfamily (IPR004709) low -2.91477760316 gnf1h02714_s_at gnf1h02714_s_at None None None None None low -2.93852782448 gnf1h03434_at gnf1h03434_at None None None None None low -2.94774356312 gnf1h00437_at gnf1h00437_at None None Homo sapiens hypothetical protein FLJ14058 (FLJ14058), mRNA. None None low -2.97039278981 gnf1h08305_at GARNL3 DKFZp761J1523;GARNL3;bA356B19.1 84253 GTPase activating RANGAP domain-like 3 small GTPase regulatory/interacting protein activity (GO:0005083) Bipartite nuclear localization signal (IPR001472);Citron-like (IPR001180);Rap/ran-GAP (IPR000331) low -3.05042707707 211259_s_at BMP7 BMP7;OP-1 655 bone morphogenetic protein 7 (osteogenic protein 1) cytokine activity (GO:0005125);growth (GO:0040007);growth factor activity (GO:0008083);skeletal development (GO:0001501) Transforming growth factor beta (IPR001839);Transforming growth factor beta (TGFb), N-terminal (IPR001111) low -3.05493575199 gnf1h02122_at KIF27 DKFZp434D0917;KIF27 55582 kinesin family member 27 ATP binding (GO:0005524);motor activity (GO:0003774) Kinesin, motor region (IPR001752) low -3.05518555936 213764_s_at MFAP5 MAGP2;MFAP5;MP25 8076 microfibrillar associated protein 5 extracellular matrix structural constituent (GO:0005201) Microfibril-associated glycoprotein (IPR008673) low -3.08016744636 gnf1h03454_at gnf1h03454_at None None None None None low -3.10168690339 207429_at SLC22A2 OCT2;SLC22A2 6582 solute carrier family 22 (organic cation transporter), member 2 fluid secretion (GO:0007589);ion transport (GO:0006811);ion transporter activity (GO:0015075);organic cation transport (GO:0015695);organic cation transporter activity (GO:0015101);transport (GO:0006810);transporter activity (GO:0005215) General substrate transporter (IPR005828);Hemopexin (IPR000585);Major facilitator superfamily (IPR007114);Organic cation transport protein (IPR004749);Sugar transporter superfamily (IPR005829) low -3.10445397346 gnf1h05011_at PKHD1L1 DKFZp586C1021;PKHD1L1;PKHDL1 93035 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 None Cell surface receptor IPT/TIG (IPR002909);Invasin/intimin cell-adhesion (IPR008964) low -3.11195200239 208175_s_at DMP1 DMP1 1758 dentin matrix acidic phosphoprotein calcium ion binding (GO:0005509);integrin binding (GO:0005178) Osteopontin (IPR002038) low -3.17710657611 213719_s_at SMARCA4 BAF190;BRG1;SMARCA4;SNF2-BETA;SNF2L4;SNF2LB;hSNF2B;hSNF2b 6597 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ATP binding (GO:0005524);ATP-dependent helicase activity (GO:0008026);DNA binding (GO:0003677);adenosinetriphosphatase (GO:0004002);helicase activity (GO:0004386);hydrolase activity (GO:0016787);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700) BRK (IPR006576);Bipartite nuclear localization signal (IPR001472);Bromodomain (IPR001487);CRISPR-associated protein, TM1810 C-terminal (IPR010149);DEAD/DEAH box helicase (IPR001410);HSA (IPR006562);Helicase, C-terminal (IPR001650);Proline-rich region (IPR000694);SNF2 related domain (IPR000330) low -3.25891179167 221057_at SPATA1 SP-2;SPAP1;SPATA1 64173 spermatogenesis associated 1 None None low -3.26300795755 206795_at F2RL2 F2RL2;PAR3 2151 coagulation factor II (thrombin) receptor-like 2 G-protein coupled receptor protein signaling pathway (GO:0007186);blood coagulation (GO:0007596);phosphatidylinositol-4,5-bisphosphate hydrolysis (GO:0007203);phosphoinositide phospholipase C activity (GO:0004435);response to wounding (GO:0009611);rhodopsin-like receptor activity (GO:0001584);thrombin receptor activity (GO:0015057) Protease-activated receptor (IPR003912);Protease-activated receptor 3 (IPR003943);Rhodopsin-like GPCR superfamily (IPR000276) low -3.26431370409 gnf1h10164_at gnf1h10164_at None None (M60789) None None low -3.28499671513 gnf1h05327_at gnf1h05327_at None None None None None low -4.00574347586 213472_at HNRPH1 HNRPH;HNRPH1;hnRNPH 3187 heterogeneous nuclear ribonucleoprotein H1 (H) RNA binding (GO:0003723);RNA processing (GO:0006396);heterogeneous nuclear ribonucleoprotein (GO:0008436);poly(U) binding (GO:0008266) RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) low -4.28885928171 206370_at PIK3CG PI3CG;PI3K;PI3Kgamma;PIK3;PIK3CG 5294 phosphoinositide-3-kinase, catalytic, gamma polypeptide 1-phosphatidylinositol 3-kinase (GO:0004429);G-protein coupled receptor protein signaling pathway (GO:0007186);inositol/phosphatidylinositol kinase activity (GO:0004428);phosphatidylinositol 3-kinase activity (GO:0016303);phosphatidylinositol-4,5-bisphosphate 3-kinase activity (GO:0046934);transferase activity (GO:0016740) ARM repeat fold (IPR008938);C2 calcium/lipid-binding domain, CaLB (IPR008973);Phosphatidylinositol 3- and 4-kinase (IPR000403);Phosphoinositide 3-kinase accessory domain PIK (IPR001263);Phosphoinositide 3-kinase, C2 domain (IPR002420);Phosphoinositide 3-kinase, ras-binding domain (IPR000341) low -4.35017434663 216068_at Hs.208769 None None MRNA; cDNA DKFZp434N021 (from clone DKFZp434N021) None None