PC-151 p<0.000010 High/Low PC-151 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 4.14203622521 207846_at POU1F1 GHF-1;PIT1;POU1F1 5449 POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) histogenesis and organogenesis (GO:0007397);negative regulation of cell proliferation (GO:0008285);organogenesis (GO:0009887);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) Homeobox (IPR001356);POU domain (IPR000327);POU homeobox (IPR007103) high 3.70531381515 215514_at Hs.21195 None None MRNA; cDNA DKFZp564M0616 (from clone DKFZp564M0616) None None high 3.46437441756 gnf1h02082_at gnf1h02082_at None None None None None high 3.44285331489 203768_s_at STS ARSC;ARSC1;ASC;SSDD;STS 412 steroid sulfatase (microsomal), arylsulfatase C, isozyme S calcium ion binding (GO:0005509);hydrolase activity (GO:0016787);metabolism (GO:0008152);pregnancy (GO:0007565);steroid catabolism (GO:0006706);steryl-sulfatase activity (GO:0004773) Sulfatase (IPR000917) high 3.42638942885 214776_x_at XYLB FLJ10343;FLJ12539;FLJ22075;XYLB 9942 xylulokinase homolog (H. influenzae) carbohydrate metabolism (GO:0005975);energy pathways (GO:0006091);kinase activity (GO:0016301);xylulokinase activity (GO:0004856) Carbohydrate kinase, FGGY (IPR000577) high 3.3962559926 215220_s_at TPR TPR 7175 translocated promoter region (to activated MET oncogene) nucleocytoplasmic transport (GO:0006913);protein-nucleus import (GO:0006606);transport (GO:0006810) None high 3.39091202956 204840_s_at EEA1 EEA1;ZFYVE2 8411 early endosome antigen 1, 162kD ATP biosynthesis (GO:0006754);hydrogen transport (GO:0006818);hydrogen-transporting two-sector ATPase activity (GO:0003936);nucleic acid binding (GO:0003676);phosphatidylinositol binding (GO:0005545);proton transport (GO:0015992);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087);Zn-finger, FYVE type (IPR000306) high 3.38210926478 76897_s_at KIAA0674 KIAA0674 23307 KIAA0674 protein folding (GO:0006457) Peptidylprolyl isomerase, FKBP-type (IPR001179) high 3.27262345194 207762_at LPAL2 APOARGC;LPAL2 80350 lipoprotein, Lp(a)-like 2 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) Kringle (IPR000001) high 3.26725804241 216758_at Hs.306750 None None CDNA: FLJ21385 fis, clone COL03356 None None high 3.25962317182 208153_s_at FAT2 CDHF8;FAT2;HFAT2;MEGF1 2196 FAT tumor suppressor homolog 2 (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515);structural molecule activity (GO:0005198) Cadherin (IPR002126);Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Laminin G (IPR001791);Type I EGF (IPR006210) high 3.2274728524 gnf1h03223_at gnf1h03223_at None None None None None high 3.17071596123 206300_s_at PTHLH HHM;MGC14611;PLP;PTHLH;PTHR;PTHRP 5744 parathyroid hormone-like hormone cAMP generating peptide activity (GO:0008492);cAMP metabolism (GO:0046058);cell proliferation (GO:0008283);cell-cell signaling (GO:0007267);excretion (GO:0007588);hormone activity (GO:0005179);lactation (GO:0007595);negative regulation of cell proliferation (GO:0008285);oncogenesis (GO:0007048);peptide hormone (GO:0005180);positive regulation of cell proliferation (GO:0008284);pregnancy (GO:0007565) Bipartite nuclear localization signal (IPR001472);Parathyroid hormone (IPR001415);Parathyroid hormone-related protein (IPR003626) high 3.15959168865 215739_s_at TUBGCP3 GCP3;Spc98p;TUBGCP3 10426 tubulin, gamma complex associated protein 3 gamma-tubulin binding (GO:0043015);microtubule nucleation (GO:0007020);microtubule-based process (GO:0007017);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Spc97/Spc98 (IPR007259) high 3.14802461219 gnf1h03195_at gnf1h03195_at None None None None None high 3.14189812805 210656_at EED EED;HEED;WAIT1 8726 embryonic ectoderm development cell adhesion (GO:0007155);embryogenesis and morphogenesis (GO:0007345);integrin binding (GO:0005178);integrin-mediated signaling pathway (GO:0007229);negative regulation of transcription of homeotic gene (Polycomb group) (GO:0006340);protein binding (GO:0005515);transcription corepressor activity (GO:0003714);transcriptional repressor activity (GO:0016564);viral replication (GO:0008166) Regulator of chromosome condensation, RCC1 (IPR000408) high 3.11170349497 211081_s_at MAP4K5 GCKR;KHS;KHS1;MAP4K5;MAPKKKK5 11183 mitogen-activated protein kinase kinase kinase kinase 5 ATP binding (GO:0005524);cAMP-dependent protein kinase activity (GO:0004691);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein kinase cascade (GO:0007243);protein serine/threonine kinase activity (GO:0004674);protein-tyrosine kinase activity (GO:0004713);response to stress (GO:0006950);small GTPase regulatory/interacting protein activity (GO:0005083);transferase activity (GO:0016740) Citron-like (IPR001180);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 3.08948230763 217263_x_at RUNX1 AML1;AMLCR1;C21orf96;CBFA2;FLJ20856;PEBP2A2;PEBP2aB;RUNX1 861 runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) ATP binding (GO:0005524);cell growth and/or maintenance (GO:0008151);development (GO:0007275);oncogenesis (GO:0007048);transcription factor activity (GO:0003700) Acute myeloid leukemia 1 protein (AML 1)/Runt (IPR000040);p53-like transcription factor, DNA-binding (IPR008967) high 3.08582428512 215002_at Hs.110613 None None CDNA: FLJ23572 fis, clone LNG12403 None None high 3.07483394498 220109_at TF PRO1557;PRO2086 7018 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 3.06172926913 221111_at IL26 AK155;IL-26;IL26 55801 interleukin 26 antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell-cell signaling (GO:0007267);cytokine activity (GO:0005125);immune response (GO:0006955) Interleukin-10 (IPR000098) high 3.04279856309 217697_at Hs.282693 None None Transcribed sequence with weak similarity to protein sp:P39188 (H.sapiens) ALU1_HUMAN Alu subfamily J sequence contamination warning entry None None high 3.03030270502 gnf1h01483_s_at PPIL3 PPIL3 53938 peptidylprolyl isomerase (cyclophilin)-like 3 isomerase activity (GO:0016853);peptidyl-prolyl cis-trans isomerase activity (GO:0003755);protein folding (GO:0006457) Peptidyl-prolyl cis-trans isomerase, cyclophilin type (IPR002130) high 3.02510532817 216533_at PCCA PCCA 5095 propionyl Coenzyme A carboxylase, alpha polypeptide ATP binding (GO:0005524);biotin binding (GO:0009374);fatty acid metabolism (GO:0006631);ligase activity (GO:0016874);metabolism (GO:0008152);propionyl-CoA carboxylase activity (GO:0004658) Biotin carboxylase, C-terminal (IPR005482);Biotin/lipoyl attachment (IPR000089);Carbamoyl-phosphate synthase L chain, ATP-binding (IPR005479);Carbamoyl-phosphate synthetase large chain, N-terminal (IPR005481) high 3.01901353004 217644_s_at SOS2 SOS2 6655 son of sevenless homolog 2 (Drosophila) guanyl-nucleotide exchange factor activity (GO:0005085);guanyl-nucleotide release factor (GO:0019839);small GTPase mediated signal transduction (GO:0007264) Bipartite nuclear localization signal (IPR001472);DH domain (IPR000219);Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif (IPR000651);Guanine-nucleotide dissociation stimulator CDC25 (IPR001895);Guanine-nucleotide dissociation stimulator, CDC24 (IPR001331);Pleckstrin-like (IPR001849);Proline-rich region (IPR000694);Ras guanine nucleotide exchange factor (IPR008937) high 2.99275684577 219380_x_at POLH POLH;RAD30A;XP-V;XPV 5429 polymerase (DNA directed), eta DNA repair (GO:0006281);DNA repair enzyme (GO:0003686);DNA-directed DNA polymerase activity (GO:0003887);damaged DNA binding (GO:0003684);eta DNA polymerase activity (GO:0015999) Bipartite nuclear localization signal (IPR001472);UMUC-like DNA-repair protein (IPR001126) high 2.97976784673 208142_at FAM12A EP3A;FAM12A;HE3-ALPHA;HE3A;HE3ALPHA 10876 family with sequence similarity 12, member A nucleic acid binding (GO:0003676);pancreatic ribonuclease activity (GO:0004522) Pancreatic ribonuclease (IPR001427) high 2.97458458117 gnf1h03703_s_at gnf1h03703_s_at None None None None None high 2.96859023394 209900_s_at SLC16A1 MCT;MCT1;SLC16A1 6566 solute carrier family 16 (monocarboxylic acid transporters), member 1 mevalonate transport (GO:0015728);mevalonate transporter activity (GO:0015130);monocarboxylate porter activity (GO:0015355);monocarboxylic acid transport (GO:0015718);monocarboxylic acid transporter activity (GO:0008028);symport (GO:0015983);symporter activity (GO:0015293);transport (GO:0006810);transporter activity (GO:0005215) Major facilitator superfamily (IPR007114);Monocarboxylate transporter (IPR004743) high 2.95827220397 222344_at C5orf13 C5orf13;D4S114;P311;PRO1873;PTZ17 9315 chromosome 5 open reading frame 13 None None high 2.93998572763 222248_s_at SIRT4 SIR2L4;SIRT4 23409 sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) DNA binding (GO:0003677);NAD+ ADP-ribosyltransferase activity (GO:0003950);chromatin silencing (GO:0006342);hydrolase activity (GO:0016787);protein amino acid ADP-ribosylation (GO:0006471) Silent information regulator protein Sir2 (IPR003000) low -2.88135917849 gnf1h10846_at gnf1h10846_at None None None None None low -2.88472150612 217257_at Hs.529638 None None (clone B3B3E13) Huntington's disease candidate region mRNA fragment. None None low -2.9158990132 gnf1h08085_s_at gnf1h08085_s_at None None None None DEAD/DEAH box helicase (IPR001410);Helicase, C-terminal (IPR001650) low -3.12086007198 gnf1h09484_at FLJ10378 DKFZp434K245;DKFZp686E0316;FLJ10378 55132 FLJ10378 protein None Cytochrome b5 (IPR001199);RNA-binding protein Lupus Lal (IPR006630) low -3.31904996795 gnf1h09284_at gnf1h09284_at None None None None None low -3.36301589496 gnf1h10637_at gnf1h10637_at None None None None None low -3.53481286658 217154_s_at EDN3 EDN3;ET3;MGC15067;MGC61498 1908 endothelin 3 cell-cell signaling (GO:0007267);circulation (GO:0008015);development (GO:0007275);morphogenesis (GO:0009653);pathogenesis (GO:0009405);perception of sound (GO:0007605);receptor binding (GO:0005102);regulation of blood pressure (GO:0008217);signal transduction (GO:0007165) Endothelin (IPR003641) low -3.80442226839 gnf1h08693_at gnf1h08693_at None None None None KRAB box (IPR001909) low -4.33613565047 gnf1h04349_at gnf1h04349_at None None None None None