PC-154 p<0.000010 High/Low PC-154 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 3.64222022671 gnf1h01934_at gnf1h01934_at None None None None None high 3.6030171216 gnf1h01810_at gnf1h01810_at None None None None None high 3.57062409098 206020_at SOCS6 CIS4;HSPC060;SOCS4;SOCS6;SSI4;STAI4;STAT4;STATI4 9306 suppressor of cytokine signaling 6 JAK-STAT cascade (GO:0007259);defense response (GO:0006952);intracellular signaling cascade (GO:0007242);regulation of cell growth (GO:0001558) SH2 motif (IPR000980);SOCS protein, C-terminal (IPR001496) high 3.48577486176 215220_s_at TPR TPR 7175 translocated promoter region (to activated MET oncogene) nucleocytoplasmic transport (GO:0006913);protein-nucleus import (GO:0006606);transport (GO:0006810) None high 3.27936785289 gnf1h09274_at HFL-EDDG1 HFL-EDDG1 10650 erythroid differentiation and denucleation factor 1 energy pathways (GO:0006091);lipoate-protein ligase B activity (GO:0016978) MSF1 (IPR006797) high 3.22358946812 214829_at AASS AASS;LKR/SDH;LKRSDH;LORSDH 10157 aminoadipate-semialdehyde synthase electron transport (GO:0006118);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);response to oxidative stress (GO:0006979);saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity (GO:0047131);saccharopine dehydrogenase (NADP+, L-lysine-forming) activity (GO:0047130) Alanine dehydrogenase/PNT, C-terminal (IPR007698);Alanine dehydrogenase/PNT, N-terminal (IPR007886);Haem peroxidase, plant/fungal/bacterial (IPR002016);Saccharopine dehydrogenase (IPR005097) high 3.19553662119 212182_at NUDT4 DIPP2;DIPP2alpha;DIPP2beta;HDCMB47P;KIAA0487;NUDT4 11163 nudix (nucleoside diphosphate linked moiety X)-type motif 4 calcium-mediated signaling (GO:0019722);cyclic nucleotide metabolism (GO:0009187);cyclic-nucleotide-mediated signaling (GO:0019935);diphosphoinositol-polyphosphate diphosphatase activity (GO:0008486);hydrolase activity (GO:0016787);intracellular signaling cascade (GO:0007242);intracellular transport (GO:0046907) NUDIX hydrolase (IPR000086) high 3.18406698224 gnf1h05431_at gnf1h05431_at None None None None None high 3.17677530746 gnf1h07370_at na None 284067 hypothetical LOC284067 None None high 3.16924233312 gnf1h01345_at gnf1h01345_at None None None None None high 3.1578038752 gnf1h09523_x_at LOC51244 LOC51244 51244 hypothetical protein LOC51244 None None high 3.14185680363 gnf1h01503_at gnf1h01503_at None None None None None high 3.0827653643 gnf1h05004_s_at gnf1h05004_s_at None None None None Nucleosome assembly protein (NAP) (IPR002164) high 3.07525131289 gnf1h01933_at FLJ46156 FLJ46156 341883 FLJ46156 protein None None high 3.05077907352 217206_at 217206_at None None Homo sapiens pseudogene for cytochrome c-like protein, clone pHGC4E1 None None high 3.03744522391 gnf1h05964_at MGC26605 MGC26605 143471 hypothetical protein MGC26605 endopeptidase activity (GO:0004175);peptidase activity (GO:0008233);proteasome endopeptidase activity (GO:0004299);ubiquitin-dependent protein catabolism (GO:0006511) 20S proteasome, A and B subunits (IPR001353);Proteasome alpha-subunit (IPR000426) high 2.95345423958 gnf1h03782_at gnf1h03782_at None None None None None high 2.941426854 32723_at CSTF1 CSTF1 1477 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa RNA binding (GO:0003723);RNA processing (GO:0006396);mRNA cleavage (GO:0006379);mRNA polyadenylation (GO:0006378) None high 2.93872162972 gnf1h00536_at C1QTNF7 C1QTNF7;CTRP7;ZACRP7 114905 C1q and tumor necrosis factor related protein 7 phosphate transport (GO:0006817) Complement C1q protein (IPR001073);TNF-like (IPR008983) high 2.92954973577 215643_at SEMA3D MGC39708;SEMA3D;Sema-Z2;coll-2 223117 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D development (GO:0007275);neurogenesis (GO:0007399);receptor activity (GO:0004872) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Semaphorin/CD100 antigen (IPR001627);Surface protein from Gram-positive cocci, anchor region (IPR001899) high 2.88980178332 gnf1h07419_s_at HOMER1 HOMER1;SYN47;Ves-1 9456 homer homolog 1 (Drosophila) transcription factor activity (GO:0003700) EVH1 (IPR000697);Helix-turn-helix, Fis-type (IPR002197);WH1 (IPR001960) high 2.8862763421 217210_at 217210_at None None None None Dynein light chain, type 1 (IPR001372) high 2.8551048774 215013_s_at USP34 KIAA0570;KIAA0729;USP34 9736 ubiquitin specific protease 34 cysteine-type endopeptidase activity (GO:0004197);ubiquitin thiolesterase activity (GO:0004221);ubiquitin-dependent protein catabolism (GO:0006511) Bipartite nuclear localization signal (IPR001472);Peptidase C19, ubiquitin carboxyl-terminal hydrolase family 2 (IPR001394) high 2.82862020458 206056_x_at SPN CD43;GPL115;LSN;SPN 6693 sialophorin (gpL115, leukosialin, CD43) binding (GO:0005488);cell adhesion molecule activity (GO:0005194);cellular defense response (GO:0006968);chemotaxis (GO:0006935);establishment and/or maintenance of cell polarity (GO:0007163);immune response (GO:0006955);negative regulation of cell adhesion (GO:0007162);signal transduction (GO:0007165);transmembrane receptor activity (GO:0004888) None high 2.82188020752 206021_at SCAND2 SCAND2 54581 SCAN domain containing 2 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554);transcription factor activity (GO:0003700) Transcriptional regulator SCAN (IPR003309) high 2.81243334229 204708_at MAPK4 ERK3;ERK3-RELATED;MAPK4;PRKM4;p63MAPK 5596 mitogen-activated protein kinase 4 ATP binding (GO:0005524);MAP kinase activity (GO:0004707);cAMP-dependent protein kinase activity (GO:0004691);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein serine/threonine kinase activity (GO:0004674);transferase activity (GO:0016740) ERK3/4 MAP kinase (IPR008350);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 2.80943196935 216519_s_at PROSC PROSC 11212 proline synthetase co-transcribed homolog (bacterial) alanine racemase activity (GO:0008784);biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554);pyridoxal phosphate binding (GO:0030170) Alanine racemase, N-terminal (IPR001608) high 2.80786298302 gnf1h02561_at gnf1h02561_at None None None None None high 2.80165857565 gnf1h01998_at B3GTL B3GTL 145173 beta 3-glycosyltransferase-like None Fringe-like (IPR003378) high 2.77734445565 220351_at CCRL1 CC-CKR-11;CCBP2;CCR10;CCR11;CCRL1;CCX-CKR;CKR-11;PPR1;VSHK1 51554 chemokine (C-C motif) receptor-like 1 C-C chemokine receptor activity (GO:0016493);G-protein coupled receptor protein signaling pathway (GO:0007186);chemokine receptor activity (GO:0004950);chemotaxis (GO:0006935);immune response (GO:0006955);rhodopsin-like receptor activity (GO:0001584) C-C chemokine receptor, type 11 (IPR005383);C-X-C chemokine receptor, type 4 (IPR001277);Chemokine receptor (IPR000355);Rhodopsin-like GPCR superfamily (IPR000276) low -2.85311984564 gnf1h05097_at gnf1h05097_at None None None None None low -2.86890710266 220800_s_at TMOD3 TMOD3;UTMOD 29766 tropomodulin 3 (ubiquitous) actin binding (GO:0003779);tropomyosin binding (GO:0005523) Tropomodulin (IPR004934) low -2.88083781252 gnf1h05492_at gnf1h05492_at None None None None None low -2.8856501976 gnf1h09402_s_at na None 400954 similar to echinoderm microtubule associated protein like 5 None None low -2.91372727094 gnf1h04127_s_at DKFZp667G2110 DKFZp667G2110 131544 hypothetical protein DKFZp667G2110 None Beta and gamma crystallin (IPR001064);Ricin B lectin domain (IPR000772);Ricin B-related lectin (IPR008997) low -2.92670975371 220281_at SLC12A1 BSC1;NKCC2;SLC12A1 6557 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 amino acid transport (GO:0006865);amino acid-polyamine transporter activity (GO:0005279);chloride transport (GO:0006821);ion transport (GO:0006811);potassium ion transport (GO:0006813);small molecule transport (GO:0006832);sodium ion transport (GO:0006814);sodium:chloride/potassium:chloride symporter activity (GO:0008511);symport (GO:0015983);symporter activity (GO:0015293);transport (GO:0006810);transporter activity (GO:0005215) Amino acid permease-associated region (IPR004841);Amino acid/polyamine transporter I (IPR002293);Helix-turn-helix, AraC type (IPR000005);Na-K-Cl co-transporter (IPR002443);Na-K-Cl co-transporter 2 (IPR002445);Na-K-Cl cotransporter superfamily (IPR004842) low -2.96669597784 gnf1h01561_s_at FLJ20449 FLJ20449 54937 hypothetical protein FLJ20449 None Basic helix-loop-helix dimerization domain bHLH (IPR001092);Bipartite nuclear localization signal (IPR001472) low -2.98963234718 gnf1h05500_at gnf1h05500_at None None None None None low -2.99243261277 207425_s_at MSF AF17q25;KIAA0991;MSF;MSF1;PNUTL4;SEPT9;SINT1 10801 MLL septin-like fusion GTP binding (GO:0005525);GTPase activity (GO:0003924) Cell division/GTP binding protein (IPR000038);Xylose isomerase (IPR001998) low -3.05295980246 gnf1h11054_at gnf1h11054_at None None None None Ribosomal protein S17e (IPR001210) low -3.05391122732 216441_at AK025573 None None None None None low -3.06056039148 gnf1h09380_s_at gnf1h09380_s_at None None None None SH2 motif (IPR000980) low -3.06625078356 gnf1h11235_at gnf1h11235_at None None None None None low -3.07652330396 210067_at AQP4 AQP4;HMIWC2;MIWC 361 aquaporin 4 excretion (GO:0007588);neurogenesis (GO:0007399);small molecule transport (GO:0006832);transport (GO:0006810);water channel activity (GO:0015250);water transporter activity (GO:0005372) Major intrinsic protein (IPR000425) low -3.17700681373 220432_s_at CYP39A1 CYP39A1 51302 cytochrome P450, family 39, subfamily A, polypeptide 1 bile acid biosynthesis (GO:0006699);bile acid catabolism (GO:0030573);digestion (GO:0007586);electron transport (GO:0006118);electron transporter activity (GO:0005489);monooxygenase activity (GO:0004497);oxysterol 7-alpha-hydroxylase activity (GO:0008396) B-class P450 (IPR002397);Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) low -3.19272100011 gnf1h05095_x_at gnf1h05095_x_at None None None None None low -3.21749058099 gnf1h08150_at gnf1h08150_at None None None None None low -3.30730142485 210343_s_at SLC22A6 HOAT1;MGC45260;OAT1;PAHT;ROAT1;SLC22A6 9356 solute carrier family 22 (organic anion transporter), member 6 alpha-ketoglutarate transport (GO:0015742);ion transport (GO:0006811);ion transporter activity (GO:0015075);organic anion transport (GO:0015711);organic anion transporter activity (GO:0008514) General substrate transporter (IPR005828);Major facilitator superfamily (IPR007114);Organic cation transport protein (IPR004749) low -3.30845872572 214981_at POSTN OSF-2;POSTN;periostin 10631 periostin, osteoblast specific factor cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);heparin binding (GO:0008201);protein binding (GO:0005515);skeletal development (GO:0001501) Beta-Ig-H3/fasciclin (IPR000782) low -3.33149761519 gnf1h09457_at gnf1h09457_at None None None None Ribosomal protein L24E (IPR000988) low -3.33342043269 gnf1h01404_at gnf1h01404_at None None None None None low -3.42241367328 211088_s_at PLK4 PLK4;SAK;STK18 10733 polo-like kinase 4 (Drosophila) ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) POLO box duplicated region (IPR000959);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -3.69154921698 216995_x_at RAF1 RAF1 5894 v-raf-1 murine leukemia viral oncogene homolog 1 ATP binding (GO:0005524);apoptosis (GO:0006915);cAMP-dependent protein kinase activity (GO:0004691);cell proliferation (GO:0008283);diacylglycerol binding (GO:0019992);intracellular signaling cascade (GO:0007242);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);protein-tyrosine kinase activity (GO:0004713);receptor signaling protein activity (GO:0005057);signal transduction (GO:0007165);transferase activity (GO:0016740) Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Raf-like Ras-binding (IPR003116);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -3.70443005556 210455_at C10orf28 C10orf28;GIDRP86;PSORT 27291 chromosome 10 open reading frame 28 electron transport (GO:0006118);oxidoreductase activity (GO:0016491) Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding (IPR008274) low -3.7196215401 205195_at AP1S1 AP19;AP1S1;CLAPS1;SIGMA1A 1174 adaptor-related protein complex 1, sigma 1 subunit endocytosis (GO:0006897);intracellular protein transport (GO:0006886);molecular_function unknown (GO:0005554);protein transporter activity (GO:0008565);vesicle transport (GO:0005480);vesicle-mediated transport (GO:0016192) Bipartite nuclear localization signal (IPR001472);Clathrin adaptor complex, small chain (IPR000804) low -4.37642148447 gnf1h00084_at MRVI1 IRAG;MRVI1 10335 murine retrovirus integration site 1 homolog oncogenesis (GO:0007048);tumor suppressor (GO:0008181) MRVI1 (IPR008677)