PC-18 p<0.000010 High/Low PC-18 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 12.0941607165 201131_s_at CDH1 CDH1;CDHE;ECAD;LCAM;UVO 999 cadherin 1, type 1, E-cadherin (epithelial) calcium ion binding (GO:0005509);calcium-dependent cell adhesion molecule activity (GO:0008014);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515);tumor suppressor (GO:0008181) Cadherin (IPR002126);Cadherin cytoplasmic region (IPR000233) high 10.5069361244 201340_s_at ENC1 CCL28;ENC-1;ENC1;NRPB;PIG10;TP53I10 8507 ectodermal-neural cortex (with BTB-like domain) actin binding (GO:0003779);development (GO:0007275);neurogenesis (GO:0007399);protein binding (GO:0005515) BTB/POZ (IPR000210);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 10.4817601116 201650_at KRT19 CK19;K19;K1CS;KRT19;MGC15366 3880 keratin 19 structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) high 10.0014121554 217238_s_at ALDOB ALDOB 229 aldolase B, fructose-bisphosphate fructose metabolism (GO:0006000);fructose-bisphosphate aldolase activity (GO:0004332);glycolysis (GO:0006096);lyase activity (GO:0016829) Fructose-bisphosphate aldolase, class-I (IPR000741) high 9.98588958389 205157_s_at KRT17 K17;KRT17;PC2;PCHC1 3872 keratin 17 protein domain specific binding (GO:0019904);structural constituent of cytoskeleton (GO:0005200) 14-3-3 protein (IPR000308);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) high 9.80633361632 209351_at KRT14 CK14;EBS3;EBS4;K14;KRT14 3861 keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) biological_process unknown (GO:0000004);structural constituent of cytoskeleton (GO:0005200);structural constituent of epidermis (GO:0030280) 14-3-3 protein (IPR000308);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Tachykinin/Neurokinin (IPR002040) high 9.70440986471 201820_at KRT5 CK5;EBS2;KRT5;KRT5A 3852 keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) structural constituent of cytoskeleton (GO:0005200) AMP-dependent synthetase and ligase (IPR000873);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Type II keratin (IPR003054) high 9.53929929921 202286_s_at TACSTD2 EGP-1;GA733;GA733-1;M1S1;TACSTD2;TROP2 4070 tumor-associated calcium signal transducer 2 cell proliferation (GO:0008283);cell surface receptor linked signal transduction (GO:0007166);receptor activity (GO:0004872);structural molecule activity (GO:0005198);tumor antigen (GO:0008222);visual perception (GO:0007601) Thyroglobulin type-1 (IPR000716) high 9.467463898 211298_s_at ALB ALB;PRO0883 213 albumin antioxidant activity (GO:0016209);body fluid osmoregulation (GO:0050891);carrier activity (GO:0005386);copper ion binding (GO:0005507);drug binding (GO:0008144);fatty acid binding (GO:0005504);lipid binding (GO:0008289);plasma protein (GO:0005209);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215);water binding (GO:0050824);water homeostasis (GO:0030104) Alpha-fetoprotein (IPR001703);Serum albumin (IPR000264) high 9.30324974387 202489_s_at FXYD3 FXYD3;MAT-8;MAT8;PLML 5349 FXYD domain containing ion transport regulator 3 chloride channel activity (GO:0005254);chloride transport (GO:0006821);ion channel activity (GO:0005216);ion transport (GO:0006811) FXYD protein (IPR000272) high 9.1278800356 201286_at SDC1 CD138;SDC;SDC1;SYND1 6382 syndecan 1 cytoskeletal protein binding (GO:0008092);syndecan (GO:0015023) Neurexin/syndecan/glycophorin C (IPR003585);Syndecan (IPR001050) high 8.50597308426 219140_s_at RBP4 RBP4 5950 retinol binding protein 4, plasma retinoid binding (GO:0005501) Invertebrate colouration protein (IPR003057);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Retinol-binding protein (IPR002449) high 8.44260854397 203407_at PPL KIAA0568;PPL 5493 periplakin structural constituent of cytoskeleton (GO:0005200) Bipartite nuclear localization signal (IPR001472) high 8.43423021622 210929_s_at AHSG AHS;AHSG;FETUA;HSGA 197 alpha-2-HS-glycoprotein acute-phase response (GO:0006953);collagen (GO:0005202);cysteine protease inhibitor activity (GO:0004869);kinase inhibitor activity (GO:0019210);pinocytosis (GO:0006907);plasma glycoprotein (GO:0005211);proteoglycan (GO:0005203);skeletal development (GO:0001501) Cysteine protease inhibitor (IPR000010);Fetuin (IPR001363);Proline-rich region (IPR000694) high 8.1671076714 205892_s_at FABP1 FABP1;FABPL;L-FABP 2168 fatty acid binding protein 1, liver cell-cell signaling (GO:0007267);fatty acid metabolism (GO:0006631);histogenesis and organogenesis (GO:0007397);lipid binding (GO:0008289);lipid transporter activity (GO:0005319);organogenesis (GO:0009887);transport (GO:0006810) Cytosolic fatty-acid binding protein (IPR000463);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) high 8.04154685435 204379_s_at FGFR3 ACH;CEK2;FGFR3;HSFGFR3EX;JTK4 2261 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) ATP binding (GO:0005524);JAK-STAT cascade (GO:0007259);MAPKKK cascade (GO:0000165);cell growth (GO:0016049);fibroblast growth factor receptor activity (GO:0005007);fibroblast growth factor receptor signaling pathway (GO:0008543);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor activity (GO:0004872);skeletal development (GO:0001501);transferase activity (GO:0016740) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 7.89477622471 203798_s_at VSNL1 HPCAL3;VILIP;VSNL1 7447 visinin-like 1 calcium ion binding (GO:0005509) Calcium-binding EF-hand (IPR002048);Recoverin (IPR001125) high 7.84180817939 208650_s_at CD24 CD24;CD24A 934 CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None high 7.81099259785 209016_s_at KRT7 CK7;K2C7;KRT7;MGC3625;SCL 3855 keratin 7 cytoskeleton organization and biogenesis (GO:0007010);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Type II keratin (IPR003054) high 7.76318617853 204855_at SERPINB5 PI5;SERPINB5;maspin 5268 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 cell motility (GO:0006928);serine-type endopeptidase inhibitor activity (GO:0004867);serpin (GO:0004868);tumor suppressor (GO:0008181) Proteinase inhibititor I4, serpin (IPR000215);Serpin B9 and maspin (IPR000240) high 7.68344187154 208190_s_at LISCH7 LISCH7;MGC10659;MGC48312 51599 liver-specific bHLH-Zip transcription factor None Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);LISCH7 (IPR008664);Short-chain dehydrogenase/reductase SDR (IPR002198);TNFR/CD27/30/40/95 cysteine-rich region (IPR001368) high 7.62481221762 205820_s_at APOC3 APOC3 345 apolipoprotein C-III apolipoprotein (GO:0005320);lipid binding (GO:0008289);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);plasma protein (GO:0005209) Apolipoprotein CIII (IPR008403) high 7.55906192222 201287_s_at SDC1 CD138;SDC;SDC1;SYND1 6382 syndecan 1 cytoskeletal protein binding (GO:0008092);syndecan (GO:0015023) Neurexin/syndecan/glycophorin C (IPR003585);Syndecan (IPR001050) high 7.47352716489 gnf1h04130_x_at gnf1h04130_x_at None None None None None high 7.45833527114 205477_s_at AMBP AMBP;HCP;ITI;ITIL;UTI 259 alpha-1-microglobulin/bikunin precursor IgA binding (GO:0019862);anti-inflammatory response (GO:0030236);binding (GO:0005488);calcium channel inhibitor activity (GO:0019855);calcium oxalate binding (GO:0046904);cell adhesion (GO:0007155);endopeptidase inhibitor activity (GO:0004866);heme binding (GO:0020037);heme catabolism (GO:0042167);plasma glycoprotein (GO:0005211);plasmin inhibitor activity (GO:0030568);pregnancy (GO:0007565);protein homodimerization activity (GO:0042803);serine-type endopeptidase inhibitor activity (GO:0004867);transport (GO:0006810);transporter activity (GO:0005215);trypsin inhibitor activity (GO:0030304) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Prostaglandin D synthase (IPR002972);Protease inhibitor I2, Kunitz metazoa (IPR002223) high 7.32656390388 gnf1h01008_at JUB JUB;MGC15563 84962 jub, ajuba homolog (Xenopus laevis) transport (GO:0006810);transporter activity (GO:0005215) Sugar transporter superfamily (IPR005829);Zn-binding protein, LIM (IPR001781) high 7.28472265803 219024_at PLEKHA1 PLEKHA1;TAPP1 59338 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 biological_process unknown (GO:0000004);phospholipid binding (GO:0005543) Pleckstrin-like (IPR001849) high 7.26963338608 210327_s_at AGXT AGT;AGT1;AGXT;AGXT1;SPAT;SPT;TLH6 189 alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) alanine-glyoxylate transaminase activity (GO:0008453);metabolism (GO:0008152);serine-pyruvate transaminase activity (GO:0004760);transaminase activity (GO:0008483);transferase activity (GO:0016740) Aminotransferase, class V (IPR000192);TONB Box N terminus (IPR010916) high 7.25627751924 205216_s_at APOH APOH;B2G1 350 apolipoprotein H (beta-2-glycoprotein I) apolipoprotein (GO:0005320);defense response (GO:0006952);defense/immunity protein activity (GO:0003793);heparin binding (GO:0008201);lipid transporter activity (GO:0005319) Sushi domain/SCR domain/CCP module (IPR000436) high 7.25393939935 gnf1h04131_x_at gnf1h04131_x_at None None None None None high 7.21415623853 209173_at AGR2 AG2;AGR2;GOB-4;HAG-2;XAG-2 10551 anterior gradient 2 homolog (Xenopus laevis) oncogenesis (GO:0007048) None high 7.16457733556 204965_at GC DBP;VDBG;VDBP 2638 group-specific component (vitamin D binding protein) actin binding (GO:0003779);carrier activity (GO:0005386);plasma protein (GO:0005209);vitamin D binding (GO:0005499);vitamin/cofactor transport (GO:0015875) Serum albumin (IPR000264);Vitamin D-binding protein (IPR000213) high 7.16126556698 gnf1h04129_x_at gnf1h04129_x_at None None None None None high 7.15882060122 AFFX-HUMRGE/M10098_5_at AFFX-HUMRGE/M10098_5_at None None M10098 Human 18S rRNA gene, complete (_5, _M, _3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 7.09187592495 209772_s_at CD24 CD24;CD24A 934 CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None high 7.08732357693 39248_at AQP3 AQP3 360 aquaporin 3 excretion (GO:0007588);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215) Major intrinsic protein (IPR000425) high 7.07257718955 218546_at FLJ14146 FLJ14146 79762 hypothetical protein FLJ14146 DNA binding (GO:0003677) None high 7.01040804251 219465_at APOA2 APOA2 336 apolipoprotein A-II glucose metabolism (GO:0006006);high-density lipoprotein (GO:0005321);lipid binding (GO:0008289);lipid catabolism (GO:0016042);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);neutrophil activation (GO:0042119);protein heterodimerization activity (GO:0046982);protein homodimerization activity (GO:0042803);response to glucose stimulus (GO:0009749) Apolipoprotein A-II (ApoA-II) (IPR006801) high 6.99517028713 266_s_at CD24 CD24;CD24A 934 CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None high 6.94284873174 204734_at KRT15 CK15;K15;K1CO;KRT15 3866 keratin 15 structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) high 6.89628527046 205041_s_at ORM1 AGP-A;AGP1;ORM;ORM1 5004 orosomucoid 1 acute-phase response (GO:0006953);acute-phase response protein activity (GO:0003794);inflammatory response (GO:0006954);plasma glycoprotein (GO:0005211);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-acid glycoprotein (IPR001500);Bipartite nuclear localization signal (IPR001472);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) high 6.83741996165 218186_at RAB25 CATX-8;RAB25 57111 RAB25, member RAS oncogene family GTP binding (GO:0005525);RAB small monomeric GTPase activity (GO:0003928);intracellular protein transport (GO:0006886);protein transport (GO:0015031);protein transporter activity (GO:0008565);small GTPase mediated signal transduction (GO:0007264);small monomeric GTPase activity (GO:0003925) GTP-binding nuclear protein Ran (IPR002041);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Sigma-54 factor interaction domain (IPR002078);Small GTP-binding protein domain (IPR005225) high 6.83705401521 202890_at MAP7 E-MAP-115;EMAP115;MAP7 9053 microtubule-associated protein 7 establishment and/or maintenance of cell polarity (GO:0007163);microtubule cytoskeleton organization and biogenesis (GO:0000226);structural molecule activity (GO:0005198) Bipartite nuclear localization signal (IPR001472);E-MAP-115 (IPR008604);Proline-rich region (IPR000694) high 6.83503716254 gnf1h05065_at gnf1h05065_at None None None None None high 6.79034507948 210233_at IL1RAP IL-1RACP;IL-1RAcP;IL1R3;IL1RAP 3556 interleukin 1 receptor accessory protein immune response (GO:0006955);inflammatory response (GO:0006954);interleukin-1 receptor activity (GO:0004908);protein complex assembly (GO:0006461);signal transducer activity (GO:0004871);transmembrane receptor activity (GO:0004888) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Interleukin-1 receptor, type I and type II (IPR004074);Interleukin-1 receptor, type I/Toll precursor (IPR004075);TIR (IPR000157) high 6.77909661796 214580_x_at KRT6A CK6A;CK6C;K6A;K6C;KRT6A;KRT6C 3853 keratin 6A cytoskeleton organization and biogenesis (GO:0007010);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Type II keratin (IPR003054) high 6.66645520968 202525_at PRSS8 PROSTASIN;PRSS8 5652 protease, serine, 8 (prostasin) chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);serine-type peptidase activity (GO:0008236);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 6.66636842628 213920_at CUTL2 CUTL2;KIAA0293 23316 cut-like 2 (Drosophila) transcription factor activity (GO:0003700) Cut homeobox (IPR007108);Homeobox (IPR001356);Homeodomain protein CUT (IPR003350) high 6.64971147455 204014_at DUSP4 DUSP4;HVH2;MKP-2;MKP2;TYP 1846 dual specificity phosphatase 4 MAP kinase phosphatase activity (GO:0017017);MAPKKK cascade (GO:0000165);hydrolase activity (GO:0016787);protein amino acid dephosphorylation (GO:0006470);protein tyrosine/threonine phosphatase activity (GO:0008330) Bipartite nuclear localization signal (IPR001472);Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Protein tyrosine phosphatase, catalytic region (IPR003595);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 6.64040364412 209771_x_at CD24 CD24;CD24A 934 CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None high 6.60046041448 209260_at SFN SFN 2810 stratifin cell proliferation (GO:0008283);negative regulation of protein kinase activity (GO:0006469);protein domain specific binding (GO:0019904);protein kinase C inhibitor activity (GO:0008426);signal transduction (GO:0007165) 14-3-3 protein (IPR000308) high 6.54669091292 204818_at HSD17B2 EDH17B2;HSD17;HSD17B2 3294 hydroxysteroid (17-beta) dehydrogenase 2 estradiol 17-beta-dehydrogenase activity (GO:0004303);estrogen biosynthesis (GO:0006703);metabolism (GO:0008152);oxidoreductase activity (GO:0016491) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (IPR003560);Glucose/ribitol dehydrogenase (IPR002347);Short-chain dehydrogenase/reductase SDR (IPR002198) high 6.47084815315 gnf1h02752_x_at gnf1h02752_x_at None None None None None high 6.46566448548 201983_s_at EGFR EGFR;ERBB;ERBB1 1956 epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) ATP binding (GO:0005524);cell proliferation (GO:0008283);electron transport (GO:0006118);electron transporter activity (GO:0005489);epidermal growth factor receptor activity (GO:0005006);epidermal growth factor receptor signaling pathway (GO:0007173);iron ion binding (GO:0005506);protein amino acid phosphorylation (GO:0006468);receptor activity (GO:0004872);transferase activity (GO:0016740) Epidermal growth-factor receptor (EGFR), L domain (IPR000494);Furin-like cysteine rich region (IPR006211);Growth factor, receptor (IPR009030);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 6.42601734415 211597_s_at HOP Cameo;HOP;LAGY;MGC20820;NECC1;OB1;SMAP31;Toto 84525 homeodomain-only protein DNA binding (GO:0003677);transcription factor activity (GO:0003700) Homeobox (IPR001356);Homeodomain-like (IPR009057) high 6.41451618386 213796_at SPRR1A SPRK;SPRR1A 6698 small proline-rich protein 1A structural molecule activity (GO:0005198) Cornifin (SPRR) (IPR003302);Proline-rich region (IPR000694) high 6.40941500878 209125_at KRT6E KRT6E 286887 keratin 6E cytoskeleton organization and biogenesis (GO:0007010);phosphorylation (GO:0016310);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Type II keratin (IPR003054) high 6.40123962308 gnf1h08340_at A1BG A1B;A1BG;ABG;GAB 1 alpha-1-B glycoprotein biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.49820087704 gnf1h05403_x_at gnf1h05403_x_at None None None None None low -5.56390476789 213451_x_at TNXB HXBL;TENX;TNX;TNXB;TNXB1;TNXB2;TNXBS;XBS 7148 tenascin XB cell adhesion (GO:0007155);cell-matrix adhesion (GO:0007160);extracellular matrix structural constituent (GO:0005201);protein binding (GO:0005515) Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210) low -5.68837971037 204083_s_at TPM2 AMCD1;DA1;TMSB;TPM2 7169 tropomyosin 2 (beta) actin binding (GO:0003779);muscle development (GO:0007517);structural constituent of muscle (GO:0008307) Tropomyosin (IPR000533) low -5.84196775807 205366_s_at HOXB6 HOX2;HOX2B;HOXB6;HU-2;Hox-2.2 3216 homeo box B6 determination of anterior/posterior axis, embryo (GO:0008595);development (GO:0007275);transcription factor activity (GO:0003700) Homeobox (IPR001356);Homeobox protein, antennapedia type (IPR001827) low -5.93656346066 209981_at PIPPIN PIPPIN;dJ347H13.2 27254 RNA-binding protein pippin DNA binding (GO:0003677);RNA binding (GO:0003723);histone mRNA 3'-end processing (GO:0006398) Cold-shock DNA-binding domain (IPR002059);Nucleic acid-binding OB-fold (IPR008994);Proline-rich region (IPR000694) low -6.56110941556 202992_at C7 None 730 complement component 7 complement activity (GO:0003811);cytolysis (GO:0019835);immune response (GO:0006955);response to pathogenic bacteria (GO:0009618) EGF-like domain (IPR006209);Factor I membrane attack complex (IPR003884);Membrane attack complex component/perforin/complement C9 (IPR001862);Sushi domain/SCR domain/CCP module (IPR000436) low -6.77303780314 217672_x_at Hs.288411 None None Transcribed sequence with weak similarity to protein pir:A43932 (H.sapiens) A43932 mucin 2 precursor, intestinal - human None None low -7.08642613471 204548_at STAR STAR;STARD1 6770 steroidogenic acute regulator C21-steroid hormone biosynthesis (GO:0006700);cholesterol binding (GO:0015485);cholesterol transporter activity (GO:0017127);lipid binding (GO:0008289);lipid transport (GO:0006869);steroid biosynthesis (GO:0006694) Lipid-binding START (IPR002913);Steroidogenic acute regulatory protein (IPR000799) low -9.34579776543 201058_s_at MYL9 LC20;MGC3505;MLC2;MRLC1;MYL9;MYRL2 10398 myosin, light polypeptide 9, regulatory calcium ion binding (GO:0005509);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048)