PC-28 p<0.000010 High/Low	PC-28 Value	ProbeId	Name	Aliases	LocusLink	Description	Function	Protein_Families	
high	7.66997923319	211161_s_at	COL3A1	COL3A1	1281	collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)	circulation (GO:0008015);collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);phosphate transport (GO:0006817)	Fibrillar collagen, C-terminal (IPR000885);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Proline-rich region (IPR000694);Surface protein from Gram-positive cocci, anchor region (IPR001899);von Willebrand factor, type C (IPR001007)	
high	7.47257977215	201909_at	RPS4Y1	MGC5070;RPS4Y;RPS4Y1	6192	ribosomal protein S4, Y-linked 1	RNA binding (GO:0003723);protein biosynthesis (GO:0006412);structural constituent of ribosome (GO:0003735)	KOW (IPR005824);RNA-binding S4 (IPR002942);Ribosomal protein S4E (IPR000876)	
high	6.96670198494	204081_at	NRGN	NRGN;RC3;hng	4900	neurogranin (protein kinase C substrate, RC3)	calmodulin binding (GO:0005516);neurogenesis (GO:0007399);signal transduction (GO:0007165)	IQ calmodulin-binding region (IPR000048)	
high	6.77209255682	203510_at	MET	HGFR;MET;RCCP2	4233	met proto-oncogene (hepatocyte growth factor receptor)	ATP binding (GO:0005524);cell proliferation (GO:0008283);cell surface receptor linked signal transduction (GO:0007166);development (GO:0007275);hepatocyte growth factor receptor activity (GO:0005008);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor activity (GO:0004872);signal transduction (GO:0007165);transferase activity (GO:0016740)	Cell surface receptor IPT/TIG (IPR002909);Protein kinase (IPR000719);Semaphorin/CD100 antigen (IPR001627);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245)	
high	6.64058531986	213317_at	Hs.21103	None	None	MRNA; cDNA DKFZp564B076 (from clone DKFZp564B076)	None	None	
high	6.54645071614	204704_s_at	ALDOB	ALDOB	229	aldolase B, fructose-bisphosphate	fructose metabolism (GO:0006000);fructose-bisphosphate aldolase activity (GO:0004332);glycolysis (GO:0006096);lyase activity (GO:0016829)	Fructose-bisphosphate aldolase, class-I (IPR000741)	
high	6.49433715077	209875_s_at	SPP1	BNSP;BSPI;ETA-1;OPN;SPP1	6696	secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)	T-helper 1 type immune response (GO:0042088);cell-cell signaling (GO:0007267);cell-matrix adhesion (GO:0007160);cytokine activity (GO:0005125);growth factor activity (GO:0008083);immune cell chemotaxis (GO:0030595);integrin binding (GO:0005178);positive regulation of T-cell proliferation (GO:0042102);protein binding (GO:0005515);regulation of myeloid blood cell differentiation (GO:0045637);skeletal development (GO:0001501)	Osteopontin (IPR002038)	
high	6.45495139474	213906_at	MYBL1	AMYB;MYBL1	4603	v-myb myeloblastosis viral oncogene homolog (avian)-like 1	DNA binding (GO:0003677);transcriptional activator activity (GO:0016563)	Myb DNA-binding domain (IPR001005)	
high	6.41261774129	206239_s_at	SPINK1	PCTT;PSTI;SPINK1;Spink3;TATI	6690	serine protease inhibitor, Kazal type 1	endopeptidase inhibitor activity (GO:0004866);serine-type endopeptidase inhibitor activity (GO:0004867)	Proteinase inhibitor I1, Kazal (IPR002350);Proteinase inhibitor I1, Kazal metazoa (IPR001239)	
high	6.39789535737	200897_s_at	KIAA0992	CGI-151;KIAA0992;SIH002	23022	palladin	amino acid metabolism (GO:0006520)	Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Proline-rich region (IPR000694)	
high	6.31286918986	202404_s_at	COL1A2	COL1A2;OI4	1278	collagen, type I, alpha 2	collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);phosphate transport (GO:0006817);skeletal development (GO:0001501);structural constituent of bone (GO:0008147)	Fibrillar collagen, C-terminal (IPR000885);Proline-rich region (IPR000694)	
high	6.09134389336	204844_at	ENPEP	APA;ENPEP;gp160	2028	glutamyl aminopeptidase (aminopeptidase A)	cell proliferation (GO:0008283);cell-cell signaling (GO:0007267);glutamyl aminopeptidase activity (GO:0004230);hydrolase activity (GO:0016787);membrane alanyl aminopeptidase activity (GO:0004179);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270)	Peptidase M1, membrane alanine aminopeptidase (IPR001930)	
high	6.02797664937	201656_at	ITGA6	CD49f;ITGA6	3655	integrin, alpha 6	cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);cell-substrate junction assembly (GO:0007044);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872)	Integrins alpha chain (IPR000413)	
high	6.02001969715	201981_at	PAPPA	ASBABP2;IGFBP-4ase;PAPA;PAPP-A;PAPPA	5069	pregnancy-associated plasma protein A	cell differentiation (GO:0030154);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);pregnancy (GO:0007565);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270)	Concanavalin A-like lectin/glucanase (IPR008985);LamG-like jellyroll fold (IPR006558);Notch (DSL) domain (IPR000800);Peptidase M43B, pregnancy-associated plasma-A (IPR008754);Sushi domain/SCR domain/CCP module (IPR000436)	
high	5.84260830748	220810_at	CLCA3	CLCA3	9629	chloride channel, calcium activated, family member 3	small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215)	None	
high	5.79683910251	201162_at	IGFBP7	FSTL2;IGFBP-7;IGFBP7;MAC25;PSF	3490	insulin-like growth factor binding protein 7	insulin-like growth factor binding (GO:0005520);negative regulation of cell proliferation (GO:0008285);regulation of cell growth (GO:0001558)	Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Insulin-like growth factor-binding protein, IGFBP (IPR000867);Proteinase inhibitor I1, Kazal (IPR002350)	
high	5.78114063797	213541_s_at	ERG	ERG	2078	v-ets erythroblastosis virus E26 oncogene like (avian)	DNA binding (GO:0003677);cell proliferation (GO:0008283);development (GO:0007275);protein amino acid phosphorylation (GO:0006468);signal transducer activity (GO:0004871);signal transduction (GO:0007165);transcription factor activity (GO:0003700)	Ets-domain (IPR000418);HSF/ETS DNA-binding (IPR002341);Sterile alpha motif (SAM)/Pointed domain (IPR003118);Winged helix DNA-binding (IPR009058)	
high	5.7677363916	207100_s_at	VAMP1	SYB1;VAMP-1;VAMP1	6843	vesicle-associated membrane protein 1 (synaptobrevin 1)	None	Synaptobrevin (IPR001388)	
high	5.76726428831	211298_s_at	ALB	ALB;PRO0883	213	albumin	antioxidant activity (GO:0016209);body fluid osmoregulation (GO:0050891);carrier activity (GO:0005386);copper ion binding (GO:0005507);drug binding (GO:0008144);fatty acid binding (GO:0005504);lipid binding (GO:0008289);plasma protein (GO:0005209);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215);water binding (GO:0050824);water homeostasis (GO:0030104)	Alpha-fetoprotein (IPR001703);Serum albumin (IPR000264)	
high	5.69508707496	220502_s_at	SLC13A1	NAS1;NaSi-1;SLC13A1	6561	solute carrier family 13 (sodium/sulfate symporters), member 1	sodium ion transport (GO:0006814);sulfate transport (GO:0008272);symport (GO:0015983);symporter activity (GO:0015293);transport (GO:0006810);transporter activity (GO:0005215)	Sodium/sulphate symporter (IPR001898)	
high	5.69106601678	204897_at	PTGER4	EP4;EP4R;PTGER4	5734	prostaglandin E receptor 4 (subtype EP4)	G-protein coupled receptor protein signaling pathway (GO:0007186);G-protein signaling\, coupled to cAMP nucleotide second messenger (GO:0007188);immune response (GO:0006955);prostaglandin E receptor activity (GO:0004957);rhodopsin-like receptor activity (GO:0001584);thromboxane receptor activity (GO:0004960)	Prostaglandin receptor (IPR001244);Prostanoid EP4 receptor (IPR001758);Prostanoid receptor (IPR008365);Rhodopsin-like GPCR superfamily (IPR000276);Thromboxane receptor (IPR001105)	
high	5.68184191322	221037_s_at	DKFZP434N1235	DKFZP434N1235	83447	hypothetical protein DKFZp434N1235	binding (GO:0005488);transport (GO:0006810);transporter activity (GO:0005215)	Adenine nucleotide translocator 1 (IPR002113);Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993)	
high	5.6355455597	217232_x_at	HBB	HBB	3043	hemoglobin, beta	oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810)	Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335)	
low	-4.34161611633	gnf1h04130_x_at	gnf1h04130_x_at	None	None	None	None	None	
low	-4.36850678508	33767_at	NEFH	KIAA0845;NEFH;NFH	4744	neurofilament, heavy polypeptide 200kDa	DNA binding (GO:0003677);molecular_function unknown (GO:0005554);neurogenesis (GO:0007399);nucleosome assembly (GO:0006334);structural molecule activity (GO:0005198)	Histone H5 (IPR005819);Intermediate filament protein (IPR001664)	
low	-4.38886430662	208928_at	POR	CYPOR;POR	5447	P450 (cytochrome) oxidoreductase	NADPH-hemoprotein reductase activity (GO:0003958);cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);oxidoreductase activity (GO:0016491)	FAD-binding (IPR003097);Flavodoxin-like domain (IPR001094);Flavodoxin/nitric oxide synthase (IPR008254);Flavoprotein pyridine nucleotide cytochrome reductase (IPR001709);Oxidoreductase FAD/NAD(P)-binding (IPR001433)	
low	-4.43206087235	222287_at	TRDN	TDN;TRDN;TRISK;TRISK51	10345	triadin	muscle contraction (GO:0006936)	Bipartite nuclear localization signal (IPR001472);Triadin (IPR010798)	
low	-4.46696393246	gnf1h02045_x_at	gnf1h02045_x_at	None	None	None	None	None	
low	-4.61560885317	gnf1h05066_x_at	gnf1h05066_x_at	None	None	None	None	None	
low	-4.68778747716	208502_s_at	PITX1	BFT;PITX1;POTX;PTX1	5307	paired-like homeodomain transcription factor 1	development (GO:0007275);embryogenesis and morphogenesis (GO:0007345);morphogenesis (GO:0009653);skeletal development (GO:0001501);transcription factor activity (GO:0003700);translation regulator activity (GO:0045182)	Homeobox (IPR001356);Paired-like homeobox (IPR007104);Paired-like homeodomain protein, OAR (IPR003654)	
low	-4.80742624949	gnf1h07966_s_at	gnf1h07966_s_at	None	None	None	None	None	
low	-5.1283617096	208962_s_at	FADS1	D5D;FADS1;FADSD5;LLCDL1;TU12	3992	fatty acid desaturase 1	C-5 sterol desaturase activity (GO:0000248);cell-cell signaling (GO:0007267);cellular response to starvation (GO:0009267);electron transport (GO:0006118);fatty acid desaturation (GO:0006636);icosanoid biosynthesis (GO:0046456);oxidoreductase activity (GO:0016491);phospholipid biosynthesis (GO:0008654);regulation of cell differentiation (GO:0045595)	ARM repeat fold (IPR008938);Cytochrome b5 (IPR001199);Fatty acid desaturase (IPR005804);Fatty acid desaturase subdomain (IPR010257)	
low	-6.59690341267	204548_at	STAR	STAR;STARD1	6770	steroidogenic acute regulator	C21-steroid hormone biosynthesis (GO:0006700);cholesterol binding (GO:0015485);cholesterol transporter activity (GO:0017127);lipid binding (GO:0008289);lipid transport (GO:0006869);steroid biosynthesis (GO:0006694)	Lipid-binding START (IPR002913);Steroidogenic acute regulatory protein (IPR000799)	
low	-8.28683273259	208963_x_at	FADS1	D5D;FADS1;FADSD5;LLCDL1;TU12	3992	fatty acid desaturase 1	C-5 sterol desaturase activity (GO:0000248);cell-cell signaling (GO:0007267);cellular response to starvation (GO:0009267);electron transport (GO:0006118);fatty acid desaturation (GO:0006636);icosanoid biosynthesis (GO:0046456);oxidoreductase activity (GO:0016491);phospholipid biosynthesis (GO:0008654);regulation of cell differentiation (GO:0045595)	ARM repeat fold (IPR008938);Cytochrome b5 (IPR001199);Fatty acid desaturase (IPR005804);Fatty acid desaturase subdomain (IPR010257)