PC-31 p<0.000010 High/Low PC-31 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 7.21929854831 AFFX-HUMRGE/M10098_5_at AFFX-HUMRGE/M10098_5_at None None M10098 Human 18S rRNA gene, complete (_5, _M, _3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 6.59207584526 AFFX-r2-Hs18SrRNA-5_at AFFX-r2-Hs18SrRNA-5_at None None M10098 Human 18S rRNA gene, complete (_5, _M, _3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 6.59173055208 AFFX-r2-Hs28SrRNA-3_at AFFX-r2-Hs28SrRNA-3_at None None M11167 Human 28S rRNA sequence, length 5025 bases, middle target bases 1666-3330 None None high 6.48171099568 205122_at TMEFF1 C9ORF2;C9orf2;H7365;TMEFF1 8577 transmembrane protein with EGF-like and two follistatin-like domains 1 serine-type endopeptidase inhibitor activity (GO:0004867) EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Proteinase inhibitor I1, Kazal (IPR002350);Type I EGF (IPR006210) high 6.36829338122 205826_at MYOM2 MYOM2;TTNAP 9172 myomesin (M-protein) 2, 165kDa muscle contraction (GO:0006936);muscle development (GO:0007517);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) Fibronectin, type III (IPR003961);Fibronectin, type III subdomain (IPR003962);Fibronectin, type III-like fold (IPR008957);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 6.08071964864 AFFX-HUMRGE/M10098_M_at AFFX-HUMRGE/M10098_M_at None None M10098 Human 18S rRNA gene, complete (_5, _M, _3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 6.06382834159 gnf1h06976_at DPP10 DPP10;DPRP3;KIAA1492 57628 dipeptidylpeptidase 10 aminopeptidase activity (GO:0004177);catalytic activity (GO:0003824);dipeptidyl-peptidase IV activity (GO:0004274);proteolysis and peptidolysis (GO:0006508) Esterase/lipase/thioesterase (IPR000379);Peptidase S9, prolyl oligopeptidase active site region (IPR001375);Peptidase S9B, dipeptidylpeptidase IV N-terminal (IPR002469) high 5.72980077375 AFFX-r2-Hs28SrRNA-5_at AFFX-r2-Hs28SrRNA-5_at None None M11167 Human 28S rRNA sequence, length 5025 bases, middle target bases 1666-3330 None None high 5.60172215473 216834_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) high 5.54341266534 220089_at C14orf160 C14orf160;FLJ12618 79944 chromosome 14 open reading frame 160 None None high 5.46473735443 209774_x_at CXCL2 CINC-2a;CXCL2;GRO2;GROb;MGSA-b;MIP-2a;MIP2;MIP2A;SCYB2 2920 chemokine (C-X-C motif) ligand 2 G-protein coupled receptor protein signaling pathway (GO:0007186);chemokine activity (GO:0008009);chemotaxis (GO:0006935);cytokine activity (GO:0005125);immune response (GO:0006955);inflammatory response (GO:0006954) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 5.35992039983 218559_s_at MAFB KRML;MAFB;MGC43127 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) DNA binding (GO:0003677) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Eukaryotic transcription factor, DNA-binding (IPR008917);Maf transcription factor (IPR004826) high 5.31762002735 205114_s_at CCL3 CCL3;LD78ALPHA;MIP-1-alpha;MIP1A;SCYA3 6348 chemokine (C-C motif) ligand 3 G-protein coupled receptor protein signaling pathway (GO:0007186);antibacterial humoral response (sensu Protostomia) (GO:0006961);antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);antiviral response protein activity (GO:0003800);calcium ion homeostasis (GO:0006874);cell adhesion molecule activity (GO:0005194);cell motility (GO:0006928);cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);cytoskeleton organization and biogenesis (GO:0007010);exocytosis (GO:0006887);immune response (GO:0006955);inflammatory response (GO:0006954);negative regulation of cell proliferation (GO:0008285);regulation of cytoskeleton (GO:0007011);regulation of viral genome replication (GO:0045069);signal transducer activity (GO:0004871);signal transduction (GO:0007165);viral replication (GO:0008166) Small chemokine, C-C subfamily (IPR000827);Small chemokine, interleukin-8 like (IPR001811) high 5.19991080002 AFFX-r2-Hs28SrRNA-M_at AFFX-r2-Hs28SrRNA-M_at None None M11167 Human 28S rRNA sequence, length 5025 bases, middle target bases 1666-3330 None None high 5.13953455782 220784_s_at UTS2 U-II;UCN2;UII;UTS2 10911 urotensin 2 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);hormone activity (GO:0005179);muscle contraction (GO:0006936);peptide hormone (GO:0005180);receptor binding (GO:0005102);regulation of blood pressure (GO:0008217) Urotensin II (IPR001483) high 5.12830377806 206157_at PTX3 PTX3;TSG-14 5806 pentaxin-related gene, rapidly induced by IL-1 beta inflammatory response (GO:0006954) Concanavalin A-like lectin/glucanase (IPR008985);Pentaxin (IPR001759) high 5.08781185362 201324_at EMP1 CL-20;EMP1;TMP 2012 epithelial membrane protein 1 cell death (GO:0008219);cell growth (GO:0016049);cell proliferation (GO:0008283);development (GO:0007275);oncogenesis (GO:0007048) PMP-22/EMP/MP20 (IPR004032);PMP-22/EMP/MP20 and claudin (IPR004031) high 5.08560704157 202887_s_at DDIT4 DDIT4;Dig2;FLJ20500;REDD-1;REDD1;RTP801 54541 DNA-damage-inducible transcript 4 None None high 5.00366469994 202859_x_at IL8 3-10C;AMCF-I;CXCL8;GCP-1;GCP1;IL-8;IL8;K60;LECT;LUCT;LYNAP;MDNCF;MONAP;NAF;NAP-1;NAP1;SCYB8;TSG-1;b-ENAP 3576 interleukin 8 G-protein coupled receptor protein signaling pathway (GO:0007186);calcium-mediated signaling (GO:0019722);cell adhesion (GO:0007155);cell motility (GO:0006928);cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);immune response (GO:0006955);inflammatory response (GO:0006954);interleukin-8 receptor binding (GO:0005153);intracellular signaling cascade (GO:0007242);negative regulation of cell proliferation (GO:0008285);neutrophil activation (GO:0042119);neutrophil chemotaxis (GO:0030593);regulation of cell adhesion (GO:0030155);regulation of retroviral genome replication (GO:0045091);signal transduction (GO:0007165) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 4.98797744306 217218_at KIAA0261 FOE;KIAA0261 23063 KIAA0261 None Bipartite nuclear localization signal (IPR001472) high 4.97232858681 211634_x_at Hs.449011 None None Partial mRNA for immunoglobulin heavy chain variable region (IGHV gene), isolate B-CLL G026 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) high 4.94829148988 206935_at PCDH8 ARCADLIN;PAPC;PCDH8 5100 protocadherin 8 calcium ion binding (GO:0005509);calcium-dependent cell adhesion molecule activity (GO:0008014);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell-cell signaling (GO:0007267);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515) Cadherin (IPR002126) high 4.90615612904 220238_s_at KLHL7 KLHL6;KLHL7;SBBI26 55975 kelch-like 7 (Drosophila) protein binding (GO:0005515) BTB/POZ (IPR000210) low -4.79348660478 214565_s_at PROL5 P-B1;PBI;PRL5;PROL5 26952 proline rich 5 (salivary) None Proline-rich region (IPR000694) low -4.81401196829 203435_s_at MME CALLA;CD10;MME;NEP 4311 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) cell-cell signaling (GO:0007267);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);neprilysin activity (GO:0004245);oncogenesis (GO:0007048);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) Peptidase M13 (IPR008753);Peptidase M13, neprilysin (IPR000718) low -4.83143666333 206494_s_at ITGA2B CD41;CD41B;GP2B;GPIIb;GTA;ITGA2B 3674 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) calcium-dependent cell adhesion molecule activity (GO:0008014);cell adhesion (GO:0007155);cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872) Integrins alpha chain (IPR000413) low -5.10333232006 206390_x_at PF4V1 CXCL4V1;PF4-ALT;PF4A;PF4V1;SCYB4V1 5197 platelet factor 4 variant 1 chemokine activity (GO:0008009);heparin binding (GO:0008201);immune response (GO:0006955) Bipartite nuclear localization signal (IPR001472);Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) low -5.10946506762 gnf1h06567_s_at gnf1h06567_s_at None None None None None low -5.11283314355 203591_s_at CSF3R CD114;CSF3R;GCSFR 1441 colony stimulating factor 3 receptor (granulocyte) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);defense response (GO:0006952);hematopoietin/interferon-class (D200-domain) cytokine receptor activity (GO:0004896);protein binding (GO:0005515);receptor activity (GO:0004872);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Long hematopoietin receptor, gp130 family 2 (IPR003529) low -5.14701787549 209116_x_at HBB HBB 3043 hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) low -5.17976394758 209591_s_at BMP7 BMP7;OP-1 655 bone morphogenetic protein 7 (osteogenic protein 1) cytokine activity (GO:0005125);growth (GO:0040007);growth factor activity (GO:0008083);skeletal development (GO:0001501) Transforming growth factor beta (IPR001839);Transforming growth factor beta (TGFb), N-terminal (IPR001111) low -5.40811303424 213506_at F2RL1 F2RL1;GPR11;PAR2 2150 coagulation factor II (thrombin) receptor-like 1 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);blood coagulation (GO:0007596);receptor activity (GO:0004872);receptor binding (GO:0005102);rhodopsin-like receptor activity (GO:0001584);thrombin receptor activity (GO:0015057) Protease-activated receptor (IPR003912);Protease-activated receptor 2 (IPR002281);Rhodopsin-like GPCR superfamily (IPR000276) low -5.49934376248 217059_at MUC7 MGC34772;MUC7 4589 mucin 7, salivary None Proline-rich region (IPR000694) low -5.51849661635 gnf1h00502_at SH3BGRL2 SH3BGRL2 83699 SH3 domain binding glutamic acid-rich protein like 2 None SH3-binding, glutamic acid-rich protein (IPR006993) low -5.63515560277 201005_at CD9 BA2;CD9;DRAP-27;MIC3;MRP-1;P24 928 CD9 antigen (p24) cell adhesion (GO:0007155);cell motility (GO:0006928);fusion of sperm to egg plasma membrane (GO:0007342);paranodal junction formation (GO:0030913);protein binding (GO:0005515) CD9/CD37/CD63 antigen (IPR000301);Tetraspanin (IPR008952) low -5.77632474121 gnf1h06906_at DKFZp313A2432 DKFZp313A2432 258010 hypothetical protein DKFZp313A2432 None None low -5.92377132378 218963_s_at KRT23 CK23;DKFZP434G032;HAIK1;K23;KRT23;MGC26158 25984 keratin 23 (histone deacetylase inducible) structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) low -5.99969346275 201058_s_at MYL9 LC20;MGC3505;MLC2;MRLC1;MYL9;MYRL2 10398 myosin, light polypeptide 9, regulatory calcium ion binding (GO:0005509);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048) low -6.00021785298 211160_x_at ACTN1 ACTN1 87 actinin, alpha 1 actin binding (GO:0003779);calcium ion binding (GO:0005509);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715) low -6.30952943865 gnf1h05735_at C18orf25 C18orf25;MGC12909 147339 chromosome 18 open reading frame 25 None None low -6.45744545261 206224_at CST1 CST1 1469 cystatin SN cysteine protease inhibitor activity (GO:0004869) Cysteine protease inhibitor (IPR000010)