PC-33 p<0.000010 High/Low PC-33 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 6.64009407807 217059_at MUC7 MGC34772;MUC7 4589 mucin 7, salivary None Proline-rich region (IPR000694) high 6.43050058888 206786_at HTN3 HIS2;HTN2;HTN3;HTN5 3347 histatin 3 antibacterial peptide activity (GO:0003797);antifungal peptide activity (GO:0003799);defense response (GO:0006952);defense response to bacteria (GO:0042742);defense response to fungi (GO:0050832);xenobiotic metabolism (GO:0006805) None high 6.32332661422 211478_s_at DPP4 ADABP;ADCP2;CD26;DPP4;DPPIV;TP103 1803 dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2) aminopeptidase activity (GO:0004177);dipeptidyl-peptidase IV activity (GO:0004274);hydrolase activity (GO:0016787);immune response (GO:0006955);prolyl oligopeptidase activity (GO:0004287);proteolysis and peptidolysis (GO:0006508) Esterase/lipase/thioesterase (IPR000379);Peptidase S9, prolyl oligopeptidase active site region (IPR001375);Peptidase S9B, dipeptidylpeptidase IV N-terminal (IPR002469) high 6.071483498 205272_s_at PRH1 PRH1 5554 proline-rich protein HaeIII subfamily 1 None Proline-rich region (IPR000694) high 5.90379486899 218885_s_at GALNT12 FLJ21212;GALNT12 79695 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12) transferase activity (GO:0016740) Glycosyl transferase, family 2 (IPR001173);Ricin B lectin domain (IPR000772);Ricin B-related lectin (IPR008997) high 5.73840171515 203434_s_at MME CALLA;CD10;MME;NEP 4311 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) cell-cell signaling (GO:0007267);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);neprilysin activity (GO:0004245);oncogenesis (GO:0007048);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) Peptidase M13 (IPR008753);Peptidase M13, neprilysin (IPR000718) high 5.57358475554 213764_s_at MFAP5 MAGP2;MFAP5;MP25 8076 microfibrillar associated protein 5 extracellular matrix structural constituent (GO:0005201) Microfibril-associated glycoprotein (IPR008673) high 5.56103751782 202888_s_at ANPEP ANPEP;CD13;LAP1;PEPN;gp150 290 alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) aminopeptidase activity (GO:0004177);hydrolase activity (GO:0016787);membrane alanyl aminopeptidase activity (GO:0004179);metallopeptidase activity (GO:0008237);pathogenesis (GO:0009405);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);zinc ion binding (GO:0008270) Peptidase M1, membrane alanine aminopeptidase (IPR001930) high 5.55739669578 206639_x_at HTN1 HIS1;HTN1 3346 histatin 1 antibacterial peptide activity (GO:0003797);antifungal peptide activity (GO:0003799);defense response (GO:0006952);defense response to bacteria (GO:0042742);defense response to fungi (GO:0050832);xenobiotic metabolism (GO:0006805) None high 5.55056740865 gnf1h09260_at EML4 C2orf2;ELP120;EML4;FLJ10942;ROPP120 27436 echinoderm microtubule associated protein like 4 microtubule-based process (GO:0007017);molecular_function unknown (GO:0005554) Calcium-binding EF-hand (IPR002048);HELP domain (IPR005108);Histidine acid phosphatase (IPR000560);Peptidase S1, chymotrypsin (IPR001254) high 5.42657492907 202952_s_at ADAM12 ADAM12;MCMP;MCMPMltna;MLTN;MLTNA 8038 a disintegrin and metalloproteinase domain 12 (meltrin alpha) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);hydrolase activity (GO:0016787);metalloendopeptidase activity (GO:0004222);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) ADAM, cysteine-rich (IPR006586);Disintegrin (IPR001762);EGF-like domain (IPR006209);Peptidase M12B, ADAM/reprolysin (IPR001590);Peptidase M12B, propeptide (IPR002870) high 5.28207746629 210664_s_at TFPI EPI;LACI;TFPI 7035 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) blood coagulation (GO:0007596);endopeptidase inhibitor activity (GO:0004866);plasma glycoprotein (GO:0005211);plasma protein (GO:0005209);serine-type endopeptidase inhibitor activity (GO:0004867) Protease inhibitor I2, Kunitz metazoa (IPR002223);Tissue factor pathway inhibitor (IPR008296) high 5.21646893005 204130_at HSD11B2 AME;AME1;HSD11B2;HSD11K 3291 hydroxysteroid (11-beta) dehydrogenase 2 11-beta-hydroxysteroid dehydrogenase activity (GO:0003845);cell-cell signaling (GO:0007267);glucocorticoid biosynthesis (GO:0006704);metabolism (GO:0008152);oxidoreductase activity (GO:0016491) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (IPR003560);Glucose/ribitol dehydrogenase (IPR002347);Short-chain dehydrogenase/reductase SDR (IPR002198) high 5.18415654937 gnf1h07966_s_at gnf1h07966_s_at None None None None None high 5.16004144657 219948_x_at FLJ21934 FLJ21934 79799 hypothetical protein FLJ21934 metabolism (GO:0008152);transferase activity, transferring hexosyl groups (GO:0016758) UDP-glucuronosyl/UDP-glucosyltransferase (IPR002213) high 5.09660623069 203886_s_at FBLN2 FBLN2 2199 fibulin 2 calcium ion binding (GO:0005509);extracellular matrix glycoprotein (GO:0005207);extracellular matrix structural constituent (GO:0005201) Anaphylatoxin/fibulin (IPR000020);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Growth factor, receptor (IPR009030) high 5.06094627177 211890_x_at CAPN3 CANP3;CANPL3;CAPN3;LGMD2;LGMD2A;MGC10767;MGC11121;MGC14344;MGC4403;nCL-1;p94 825 calpain 3, (p94) calcium ion binding (GO:0005509);calpain activity (GO:0004198);cysteine-type peptidase activity (GO:0008234);hydrolase activity (GO:0016787);muscle development (GO:0007517);proteolysis and peptidolysis (GO:0006508);signal transducer activity (GO:0004871) Calcium-binding EF-hand (IPR002048);Peptidase C2, calpain (IPR001300);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 5.03082892617 210078_s_at KCNAB1 AKR6A3;KCNA1B;KCNAB1;KV-BETA-1;Kvb1.3;hKvBeta3;hKvb3 7881 potassium voltage-gated channel, shaker-related subfamily, beta member 1 ion channel activity (GO:0005216);ion transport (GO:0006811);potassium channel regulator activity (GO:0015459);potassium ion transport (GO:0006813);voltage-gated potassium channel activity (GO:0005249) Aldo/keto reductase (IPR001395);KCNAB voltage-gated K+ channel, beta subunit (IPR005399);KCNAB voltage-gated K+ channel, beta subunit core region (IPR005983);KCNAB voltage-gated K+ channel, beta-1 subunit (IPR005400);KCNAB voltage-gated K+ channel, beta-3 subunit (IPR005402) high 4.98270176029 gnf1h06965_s_at MUC7 MGC34772;MUC7 4589 mucin 7, salivary None Proline-rich region (IPR000694) high 4.82995140721 215330_at Hs.226103 None None MRNA; cDNA DKFZp564G222 (from clone DKFZp564G222) None None high 4.74038965579 203791_at DMXL1 DMXL1 1657 Dmx-like 1 protein binding (GO:0005515);proteolysis and peptidolysis (GO:0006508);subtilase activity (GO:0004289) Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209) high 4.7105141245 210046_s_at IDH2 ICD-M;IDH;IDH2;IDHM;IDP;mNADP-IDH 3418 isocitrate dehydrogenase 2 (NADP+), mitochondrial carbohydrate metabolism (GO:0005975);glyoxylate cycle (GO:0006097);isocitrate dehydrogenase (NADP+) activity (GO:0004450);main pathways of carbohydrate metabolism (GO:0006092);metabolism (GO:0008152);oxidoreductase activity (GO:0016491);tricarboxylic acid cycle (GO:0006099) Isocitrate dehydrogenase NADP-dependent, eukaryotic (IPR004790);Isocitrate/isopropylmalate dehydrogenase (IPR001804) high 4.70135693376 213975_s_at LYZ LYZ 4069 lysozyme (renal amyloidosis) amyloid protein (GO:0005208);antimicrobial humoral response (sensu Protostomia) (GO:0006960);bacteriolytic toxin activity (GO:0015642);carbohydrate metabolism (GO:0005975);cell wall catabolism (GO:0016998);cytolysis (GO:0019835);hydrolase activity, acting on glycosyl bonds (GO:0016798);inflammatory response (GO:0006954);lysin activity (GO:0015465);lysozyme activity (GO:0003796);structural molecule activity (GO:0005198) Glycoside hydrolase, family 22 (IPR001916);Glycoside hydrolase, family 22, lysozyme (IPR000974) high 4.7011358417 209803_s_at PHLDA2 BRW1C;BWR1C;HLDA2;IPL;PHLDA2;TSSC3 7262 pleckstrin homology-like domain, family A, member 2 DNA binding (GO:0003677);apoptosis (GO:0006915);imprinting (GO:0006349) Pleckstrin-like (IPR001849) low -4.83580630703 204914_s_at SOX11 SOX11 6664 SRY (sex determining region Y)-box 11 DNA binding (GO:0003677);neurogenesis (GO:0007399);transcription activating factor (GO:0003710) HMG1/2 (high mobility group) box (IPR000910) low -4.85268167136 217767_at C3 ASP 718 complement component 3 G-protein coupled receptor protein signaling pathway (GO:0007186);complement activity (GO:0003811);endopeptidase inhibitor activity (GO:0004866);immune response (GO:0006955);inflammatory response (GO:0006954);receptor binding (GO:0005102);signal transduction (GO:0007165) Alpha-2-macroglobulin (IPR001599);Alpha-2-macroglobulin, N-terminal (IPR002890);Alpha-macroglobulin, receptor-binding (IPR009048);Anaphylatoxin/fibulin (IPR000020);Complement C3a/C4a/C5a anaphylatoxin (IPR001840);Netrin, C-terminal (IPR001134);Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (IPR008930) low -4.86204516793 221704_s_at FLJ12750 FLJ12750 79720 hypothetical protein FLJ12750 None Modifier of rudimentary (Mod (IPR009851);Proline-rich region (IPR000694) low -5.20921401043 gnf1h05492_at gnf1h05492_at None None None None None low -5.22871716733 218980_at FHOD3 FHOD3;FHOS2;FLJ22297;FLJ22717;KIAA1695 80206 formin homology 2 domain containing 3 actin binding (GO:0003779) Actin-binding FH2 (IPR003104) low -5.48031575691 220109_at TF PRO1557;PRO2086 7018 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) low -5.633422854 212843_at NCAM1 CD56;MSK39;NCAM;NCAM1 4684 neural cell adhesion molecule 1 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell-cell signaling (GO:0007267);protein binding (GO:0005515) Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Neural cell adhesion (IPR009138) low -5.65591893968 203423_at RBP1 CRABP-I;CRBP;CRBP1;RBP1;RBPC 5947 retinol binding protein 1, cellular lipid binding (GO:0008289);retinoid binding (GO:0005501);retinol binding (GO:0019841);transport (GO:0006810);transporter activity (GO:0005215);vitamin A metabolism (GO:0006776) Cytosolic fatty-acid binding protein (IPR000463);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) low -5.97130781356 209994_s_at ABCB1 ABC20;ABCB1;CD243;CLCS;GP170;MDR1;P-gp;PGY1 5243 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ATP binding (GO:0005524);ATP-binding cassette (ABC) transporter activity (GO:0004009);drug resistance (GO:0009315);nucleotide binding (GO:0000166);response to drug (GO:0042493);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215) AAA ATPase (IPR003593);ABC transporter (IPR003439);ABC transporter, transmembrane region (IPR001140);Bipartite nuclear localization signal (IPR001472) low -6.12420318804 209560_s_at DLK1 DLK1;FA1;PREF1;Pref-1;ZOG;pG2 8788 delta-like 1 homolog (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);development (GO:0007275);molecular_function unknown (GO:0005554);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210);Type II EGF-like signature (IPR001438) low -6.30925829892 215294_s_at SMARCA1 SMARCA1;SNF2L;SNF2L1;SNF2LB;SWI2 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 ATP binding (GO:0005524);ATP-dependent helicase activity (GO:0008026);DNA binding (GO:0003677);adenosinetriphosphatase (GO:0004002);chromatin remodeling (GO:0006338);helicase activity (GO:0004386);translation regulator activity (GO:0045182) Bipartite nuclear localization signal (IPR001472);DEAD/DEAH box helicase (IPR001410);Helicase, C-terminal (IPR001650);Myb DNA-binding domain (IPR001005);SNF2 related domain (IPR000330) low -6.44295954804 205029_s_at FABP7 B-FABP;FABP7;FABPB;MRG 2173 fatty acid binding protein 7, brain fatty acid metabolism (GO:0006631);intracellular transporter activity (GO:0005478);lipid binding (GO:0008289);negative regulation of cell proliferation (GO:0008285);neurogenesis (GO:0007399);transport (GO:0006810);transporter activity (GO:0005215) Cytosolic fatty-acid binding protein (IPR000463);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566)