PC-35 p<0.000010 High/Low PC-35 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 7.22612517223 206140_at LHX2 LH2;LHX2;hLhx2 9355 LIM homeobox 2 oncogenesis (GO:0007048);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) Bipartite nuclear localization signal (IPR001472);Homeobox (IPR001356);LIM homeobox (IPR007107);Zn-binding protein, LIM (IPR001781) high 6.94287397209 204337_at RGS4 MGC2124;MGC60244;RGP4;RGS4 5999 regulator of G-protein signalling 4 GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);regulation of G-protein coupled receptor protein signaling pathway (GO:0008277);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Regulator of G protein (IPR000342) high 6.19862416189 205827_at CCK CCK 885 cholecystokinin hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Gastrin/cholecystokinin peptide hormone (IPR001651) high 5.81365226633 206018_at FOXG1B BF1;FKH2;FKHL1;FKHL4;FOXG1B;HBF-1;HFK1;QIN 2290 forkhead box G1B DNA binding (GO:0003677);development (GO:0007275);embryogenesis and morphogenesis (GO:0007345);morphogenesis (GO:0009653);transcription factor activity (GO:0003700) Bipartite nuclear localization signal (IPR001472);Fork head transcription factor (IPR001766);Proline-rich region (IPR000694);Winged helix DNA-binding (IPR009058) high 5.78254368961 204134_at PDE2A PDE2A 5138 phosphodiesterase 2A, cGMP-stimulated 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);cGMP-stimulated cyclic-nucleotide phosphodiesterase activity (GO:0004118);catalytic activity (GO:0003824);hydrolase activity (GO:0016787);signal transduction (GO:0007165) 3'5'-cyclic nucleotide phosphodiesterase (IPR002073);GAF (IPR003018);Metal-dependent phosphohydrolase, HD region (IPR003607) high 5.68017239486 204697_s_at CHGA CGA;CHGA 1113 chromogranin A (parathyroid secretory protein 1) calcium ion binding (GO:0005509);regulation of blood pressure (GO:0008217) Chromogranin A/B (IPR001819);Chromogranin/secretogranin (IPR001990) high 5.61949698766 213479_at NPTX2 NP-II;NP2;NPTX2 4885 neuronal pentraxin II heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);molecular_function unknown (GO:0005554);regulation of synapse (GO:0007273);sugar binding (GO:0005529);transport (GO:0006810) Concanavalin A-like lectin/glucanase (IPR008985);Pentaxin (IPR001759) high 5.14333729131 213921_at SST SMST;SST 6750 somatostatin G-protein coupled receptor protein signaling pathway (GO:0007186);cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);digestion (GO:0007586);hormone activity (GO:0005179);negative regulation of cell proliferation (GO:0008285);peptide hormone (GO:0005180);response to nutrients (GO:0007584) Somatostatin/Cortistatin (IPR004250) high 5.11483609694 204081_at NRGN NRGN;RC3;hng 4900 neurogranin (protein kinase C substrate, RC3) calmodulin binding (GO:0005516);neurogenesis (GO:0007399);signal transduction (GO:0007165) IQ calmodulin-binding region (IPR000048) high 4.88821301714 gnf1h08748_s_at FLJ39822 FLJ39822 151258 hypothetical protein FLJ39822 amino acid transport (GO:0006865);amino acid-polyamine transporter activity (GO:0005279) Amino acid/polyamine transporter II (IPR002422) high 4.73055695303 208069_x_at GH1 GH-N;GH1;GHN 2688 growth hormone 1 hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Somatotropin hormone (IPR001400) high 4.69458627143 201340_s_at ENC1 CCL28;ENC-1;ENC1;NRPB;PIG10;TP53I10 8507 ectodermal-neural cortex (with BTB-like domain) actin binding (GO:0003779);development (GO:0007275);neurogenesis (GO:0007399);protein binding (GO:0005515) BTB/POZ (IPR000210);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 4.57133453171 209598_at PNMA2 KIAA0883;MA2;MM2;PNMA2 10687 paraneoplastic antigen MA2 None None high 4.55551996236 gnf1h04204_at gnf1h04204_at None None None None None high 4.54663963403 205825_at PCSK1 NEC1;PC1;PC3;PCSK1;SPC3 5122 proprotein convertase subtilisin/kexin type 1 cell-cell signaling (GO:0007267);hydrolase activity (GO:0016787);metabolism (GO:0008152);proprotein convertase 1 activity (GO:0004285);proteolysis and peptidolysis (GO:0006508);subtilase activity (GO:0004289) Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209);Proprotein convertase, P domain (IPR002884);Proteinase inhibitor, propeptide (IPR009020) high 4.50546699242 216356_x_at BAIAP3 BAIAP3;BAP3;KIAA0734 8938 BAI1-associated protein 3 neurotransmitter secretion (GO:0007269);protein C-terminus binding (GO:0008022) C2 calcium/lipid-binding domain, CaLB (IPR008973);C2 domain (IPR000008);Protein of unknown function DUF1041 (IPR010439) high 4.46371026505 219106_s_at KBTBD10 KBTBD10;SARCOSIN 10324 kelch repeat and BTB (POZ) domain containing 10 protein binding (GO:0005515);striated muscle contraction (GO:0006941) BTB/POZ (IPR000210);Methylated-DNA-[protein]-cysteine S-methyltransferase (IPR001497) high 4.43949259227 207558_s_at PITX2 ARP1;Brx1;IDG2;IGDS;IGDS2;IHG2;IRID2;MGC20144;Otlx2;PITX2;PTX2;RGS;RIEG;RIEG1 5308 paired-like homeodomain transcription factor 2 determination of left/right symmetry (GO:0007368);development (GO:0007275);histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);transcription factor activity (GO:0003700) Homeobox (IPR001356);Paired-like homeobox (IPR007104);Paired-like homeodomain protein, OAR (IPR003654) high 4.37798581791 201743_at CD14 CD14;NDUFA2 929 CD14 antigen GPI-anchored membrane-bound receptor (GO:0015025);NADH dehydrogenase (ubiquinone) activity (GO:0008137);NADH dehydrogenase activity (GO:0003954);antibacterial peptide activity (GO:0003797);apoptosis (GO:0006915);cell surface receptor linked signal transduction (GO:0007166);energy pathways (GO:0006091);immune response (GO:0006955);inflammatory response (GO:0006954);oxidoreductase activity (GO:0016491);peptidoglycan receptor activity (GO:0016019);phagocytosis (GO:0006909) Mitochondrial ribosome (IPR007741) high 4.33765556079 205478_at PPP1R1A PPP1R1A 5502 protein phosphatase 1, regulatory (inhibitor) subunit 1A glycogen metabolism (GO:0005977);protein phosphatase inhibitor activity (GO:0004864);signal transduction (GO:0007165);type 1 serine/threonine specific protein phosphatase inhibitor activity (GO:0004865) Protein phosphatase inhibitor, 1DARPP-32 (IPR008466) high 4.3021584101 220551_at SLC17A6 DNPI;SLC17A6;VGLUT2 57084 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 transport (GO:0006810);transporter activity (GO:0005215) Major facilitator superfamily (IPR007114) high 4.29634311561 217121_at TNKS PARPL;TIN1;TINF1;TNKS;TNKS1 8658 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase NAD+ ADP-ribosyltransferase activity (GO:0003950);protein binding (GO:0005515);telomerase-dependent telomere maintenance (GO:0007004);transferase activity, transferring glycosyl groups (GO:0016757) Proline-rich region (IPR000694);Sterile alpha motif SAM (IPR001660) low -5.02998444684 210655_s_at FOXO3A AF6q21;FKHRL1;FKHRL1P2;FOXO3A;MGC12739;MGC31925 2309 forkhead box O3A apoptosis (GO:0006915);cell growth and/or maintenance (GO:0008151);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) Fork head transcription factor (IPR001766) low -5.14293289329 208153_s_at FAT2 CDHF8;FAT2;HFAT2;MEGF1 2196 FAT tumor suppressor homolog 2 (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515);structural molecule activity (GO:0005198) Cadherin (IPR002126);Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Laminin G (IPR001791);Type I EGF (IPR006210) low -5.15198085922 202178_at PRKCZ PKC2;PRKCZ 5590 protein kinase C, zeta ATP binding (GO:0005524);atypical protein kinase C activity (GO:0004700);cAMP-dependent protein kinase activity (GO:0004691);diacylglycerol binding (GO:0019992);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);signal transduction (GO:0007165);transferase activity (GO:0016740) Octicosapeptide/Phox/Bem1p (IPR000270);Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -5.15732467215 214387_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) low -5.18628080407 211841_s_at TNFRSF25 APO-3;DDR3;DR3;LARD;TNFRSF12;TNFRSF25;TR3;TRAMP;WSL-1;WSL-LR 8718 tumor necrosis factor receptor superfamily, member 25 NGF/TNF (6 C-domain) receptor activity (GO:0005027);apoptosis (GO:0006915);apoptosis regulator activity (GO:0016329);cell surface receptor linked signal transduction (GO:0007166);molecular_function unknown (GO:0005554);receptor activity (GO:0004872);signal transduction (GO:0007165);tumor necrosis factor receptor activity (GO:0005031) Death domain (IPR000488);TNFR/CD27/30/40/95 cysteine-rich region (IPR001368) low -5.27039006253 212670_at ELN ELN;SVAS;WBS 2006 elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) biological_process unknown (GO:0000004);cell proliferation (GO:0008283);circulation (GO:0008015);extracellular matrix constituent conferring elasticity (GO:0030023);extracellular matrix structural constituent (GO:0005201);histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);respiratory gaseous exchange (GO:0007585) Peptidylprolyl isomerase, FKBP-type (IPR001179);Tropoelastin (IPR003979) low -5.28317475864 217046_s_at AGER AGER;MGC22357;RAGE 177 advanced glycosylation end product-specific receptor cell surface receptor linked signal transduction (GO:0007166);inflammatory response (GO:0006954);receptor activity (GO:0004872);response to wounding (GO:0009611);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.38316197837 206914_at CRTAM CRTAM 56253 class-I MHC-restricted T cell associated molecule None Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.44598190809 208457_at GABRD GABRD;MGC45284 2563 gamma-aminobutyric acid (GABA) A receptor, delta GABA-A receptor activity (GO:0004890);extracellular ligand-gated ion channel activity (GO:0005230);ion channel activity (GO:0005216);ion transport (GO:0006811);neurotransmitter receptor activity (GO:0030594);signal transduction (GO:0007165);small molecule transport (GO:0006832);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Gamma-aminobutyric-acid A receptor delta subunit (IPR008098);Neurotransmitter-gated ion-channel (IPR006201);Neurotransmitter-gated ion-channel ligand binding domain (IPR006202);Neurotransmitter-gated ion-channel transmembrane region (IPR006029);TonB-dependent receptor (IPR000531) low -5.45675540917 206230_at LHX1 LHX1;LIM-1;LIM1 3975 LIM homeobox 1 RNA polymerase II transcription factor activity (GO:0003702);histogenesis and organogenesis (GO:0007397);neurogenesis (GO:0007399);oncogenesis (GO:0007048);transcription factor activity (GO:0003700) Bipartite nuclear localization signal (IPR001472);Helix-turn-helix motif, lambda-like repressor (IPR000047);Homeobox (IPR001356);LIM homeobox (IPR007107);Proline-rich region (IPR000694);Zn-binding protein, LIM (IPR001781) low -5.49185006629 211343_s_at COL13A1 COL13A1 1305 collagen, type XIII, alpha 1 collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);phosphate transport (GO:0006817) Proline-rich region (IPR000694) low -5.54465308612 209016_s_at KRT7 CK7;K2C7;KRT7;MGC3625;SCL 3855 keratin 7 cytoskeleton organization and biogenesis (GO:0007010);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Type II keratin (IPR003054) low -5.55601950847 gnf1h07166_at DKFZp761P0423 DKFZp761P0423 157285 hypothetical protein DKFZp761P0423 ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);transferase activity (GO:0016740) Aldehyde dehydrogenase (IPR002086);Protein kinase (IPR000719) low -5.57616611301 205982_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) low -5.7417213084 gnf1h06672_at ZNF521 DKFZp564D0764;EHZF;Evi3;ZNF521 25925 zinc finger protein 521 nucleic acid binding (GO:0003676);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) low -5.7701728529 gnf1h09015_at MGC33926 MGC33926 130733 hypothetical protein MGC33926 structural molecule activity (GO:0005198) Claudin tight junction protein (IPR006187) low -6.01800530465 gnf1h10357_at gnf1h10357_at None None None None None low -6.06184829688 207980_s_at CITED2 CITED2;MRG1;P35SRJ 10370 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein binding (GO:0005515);transcription factor activity (GO:0003700) CITED (IPR007576) low -6.06310288489 207182_at GABRA6 GABRA6 2559 gamma-aminobutyric acid (GABA) A receptor, alpha 6 GABA-A receptor activity (GO:0004890);benzodiazepine receptor activity (GO:0008503);chloride transport (GO:0006821);extracellular ligand-gated ion channel activity (GO:0005230);gamma-aminobutyric acid signaling pathway (GO:0007214);ion channel activity (GO:0005216);ion transport (GO:0006811);neurotransmitter receptor activity (GO:0030594);signal transduction (GO:0007165);small molecule transport (GO:0006832);transport (GO:0006810) Gamma-aminobutyric-acid A receptor, alpha 6 subunit (IPR005436);Gamma-aminobutyric-acid A receptor, alpha subunit (IPR001390);Neurotransmitter-gated ion-channel (IPR006201);Neurotransmitter-gated ion-channel ligand binding domain (IPR006202);Neurotransmitter-gated ion-channel transmembrane region (IPR006029) low -6.10641531051 218835_at SFTPA2 COLEC5;SFTPA2;SP-A2;SPAII 6436 surfactant, pulmonary-associated protein A2 apolipoprotein (GO:0005320);heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);lipid transporter activity (GO:0005319);phosphate transport (GO:0006817);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sugar binding (GO:0005529);surfactant activity (GO:0019214) C-type lectin (IPR001304);Proline-rich region (IPR000694) low -6.44051869279 219327_s_at GPRC5C GPRC5C;RAIG-3;RAIG3 55890 G protein-coupled receptor, family C, group 5, member C G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);receptor activity (GO:0004872) G-protein coupled receptor family 3, metabotropic glutamate receptor-like (IPR000337);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.51288245034 209810_at SFTPB PSP-B;SFTB3;SFTP3;SFTPB;SP-B 6439 surfactant, pulmonary-associated protein B histogenesis and organogenesis (GO:0007397);lipid metabolism (GO:0006629);organogenesis (GO:0009887);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sphingolipid metabolism (GO:0006665);surfactant activity (GO:0019214) Saposin (IPR008373);Saposin B (IPR008139);Saposin B subdomain (IPR008140);Saposin type A (IPR003119);Saposin-like type B, 1 (IPR007856);Saposin-like type B, 2 (IPR008138);Surfactant protein B (IPR008137) low -6.63090165555 207276_at CDR1 CDR;CDR1;CDR34;CDR62A 1038 cerebellar degeneration-related protein 1, 34kDa cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048) None low -7.19925403585 37004_at SFTPB PSP-B;SFTB3;SFTP3;SFTPB;SP-B 6439 surfactant, pulmonary-associated protein B histogenesis and organogenesis (GO:0007397);lipid metabolism (GO:0006629);organogenesis (GO:0009887);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sphingolipid metabolism (GO:0006665);surfactant activity (GO:0019214) Saposin (IPR008373);Saposin B (IPR008139);Saposin B subdomain (IPR008140);Saposin type A (IPR003119);Saposin-like type B, 1 (IPR007856);Saposin-like type B, 2 (IPR008138);Surfactant protein B (IPR008137) low -7.57578232777 205747_at CBLN1 CBLN1 869 cerebellin 1 precursor neurogenesis (GO:0007399) Complement C1q protein (IPR001073);TNF-like (IPR008983) low -8.0419844786 201650_at KRT19 CK19;K19;K1CS;KRT19;MGC15366 3880 keratin 19 structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) low -8.29536742708 206373_at ZIC1 ZIC;ZIC1;ZNF201 7545 Zic family member 1 (odd-paired homolog, Drosophila) DNA binding (GO:0003677);behavior (GO:0007610);development (GO:0007275);inner ear morphogenesis (GO:0042472);neurogenesis (GO:0007399);pattern specification (GO:0007389);regulation of smoothened receptor signaling pathway (GO:0008589);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270);zinc-mediated transcriptional activator activity (GO:0042156) Zn-finger, C2H2 type (IPR007087)