PC-36 p<0.000010 High/Low PC-36 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 6.8289148212 gnf1h07051_s_at gnf1h07051_s_at None None None None Immunoglobulin V-type (IPR003596);Immunoglobulin/major histocompatibility complex (IPR003006) high 6.34627059584 210715_s_at SPINT2 HAI-2;HAI2;Kop;SPINT2 10653 serine protease inhibitor, Kunitz type, 2 cell motility (GO:0006928);endopeptidase inhibitor activity (GO:0004866);serine-type endopeptidase inhibitor activity (GO:0004867) Protease inhibitor I2, Kunitz metazoa (IPR002223) high 6.29528040272 205372_at PLAG1 PLAG1;PSA;SGPA 5324 pleiomorphic adenoma gene 1 nucleic acid binding (GO:0003676);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) high 6.2649285574 gnf1h00769_at ECRG4 ECRG4 84417 esophageal cancer related gene 4 protein None None high 6.07022058844 206624_at USP9Y DFFRY;USP9Y 8287 ubiquitin specific protease 9, Y-linked (fat facets-like, Drosophila) cysteine-type endopeptidase activity (GO:0004197);cysteine-type peptidase activity (GO:0008234);hydrolase activity (GO:0016787);spermatogenesis (GO:0007283);ubiquitin thiolesterase activity (GO:0004221);ubiquitin-dependent protein catabolism (GO:0006511);ubiquitin-specific protease activity (GO:0004843) Peptidase C19, ubiquitin carboxyl-terminal hydrolase family 2 (IPR001394) high 6.06901428746 216834_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) high 6.05414865673 206042_x_at SNRPN HCERN3;SM-D;SMN;SNRNP-N;SNRPN;SNURF 6638 small nuclear ribonucleoprotein polypeptide N RNA binding (GO:0003723);RNA splicing (GO:0008380);biological_process unknown (GO:0000004);mRNA processing (GO:0006397);mRNA splicing (GO:0006371);molecular_function unknown (GO:0005554);pre-mRNA splicing factor activity (GO:0008248);small nuclear ribonucleoprotein (GO:0003734) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);SNURFRPN4 (IPR009847);Small nuclear ribonucleoprotein (Sm protein) (IPR001163) high 5.94083414105 203807_x_at CSH2 CSB;CSH2 1443 chorionic somatomammotropin hormone 2 cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);pregnancy (GO:0007565);signal transduction (GO:0007165) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) high 5.85674850735 209173_at AGR2 AG2;AGR2;GOB-4;HAG-2;XAG-2 10551 anterior gradient 2 homolog (Xenopus laevis) oncogenesis (GO:0007048) None high 5.82637439584 205569_at LAMP3 DC-LAMP;DCLAMP;LAMP;LAMP3;TSC403 27074 lysosomal-associated membrane protein 3 cell proliferation (GO:0008283);oncogenesis (GO:0007048) Lysosome-associated membrane glycoprotein (Lamp)/CD68 (IPR002000) high 5.76393655788 208356_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) high 5.75465332707 gnf1h10247_at gnf1h10247_at None None (AF022250) None None high 5.64572393231 209560_s_at DLK1 DLK1;FA1;PREF1;Pref-1;ZOG;pG2 8788 delta-like 1 homolog (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);development (GO:0007275);molecular_function unknown (GO:0005554);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210);Type II EGF-like signature (IPR001438) high 5.62715181244 208357_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) high 5.56311202419 202493_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) high 5.55404095997 209170_s_at GPM6B GPM6B;M6B 2824 glycoprotein M6B molecular_function unknown (GO:0005554);neurogenesis (GO:0007399) Myelin proteolipid protein PLP (IPR001614) high 5.55154306913 206639_x_at HTN1 HIS1;HTN1 3346 histatin 1 antibacterial peptide activity (GO:0003797);antifungal peptide activity (GO:0003799);defense response (GO:0006952);defense response to bacteria (GO:0042742);defense response to fungi (GO:0050832);xenobiotic metabolism (GO:0006805) None high 5.48712185576 201522_x_at SNRPN HCERN3;SM-D;SMN;SNRNP-N;SNRPN;SNURF 6638 small nuclear ribonucleoprotein polypeptide N RNA binding (GO:0003723);RNA splicing (GO:0008380);biological_process unknown (GO:0000004);mRNA processing (GO:0006397);mRNA splicing (GO:0006371);molecular_function unknown (GO:0005554);pre-mRNA splicing factor activity (GO:0008248);small nuclear ribonucleoprotein (GO:0003734) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);SNURFRPN4 (IPR009847);Small nuclear ribonucleoprotein (Sm protein) (IPR001163) high 5.43925437362 211739_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.93641767032 219370_at REPRIMO REPRIMO 56475 candidate mediator of the p53-dependent G2 arrest None None low -3.99982448943 207935_s_at KRT13 CK13;K13;KRT13;MGC3781 3860 keratin 13 structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) low -4.25388857878 202003_s_at ACAA2 ACAA2;DSAEC 10449 acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) acetyl-CoA C-acyltransferase activity (GO:0003988);acyltransferase activity (GO:0008415);fatty acid metabolism (GO:0006631);transferase activity (GO:0016740) Thiolase (IPR002155) low -4.30225332866 209540_at IGF1 IGF1;IGFI 3479 insulin-like growth factor 1 (somatomedin C) DNA replication (GO:0006260);RAS protein signal transduction (GO:0007265);cell motility (GO:0006928);glycolate metabolism (GO:0009441);growth factor activity (GO:0008083);hormone activity (GO:0005179);insulin-like growth factor receptor binding (GO:0005159);muscle development (GO:0007517);physiological process (GO:0007582);positive regulation of cell proliferation (GO:0008284);prothoracicotrophic hormone activity (GO:0018445);signal transduction (GO:0007165);skeletal development (GO:0001501) Insulin/IGF/relaxin (IPR004825) low -4.33277196518 204457_s_at GAS1 GAS1 2619 growth arrest-specific 1 molecular_function unknown (GO:0005554);negative regulation of cell proliferation (GO:0008285) None low -4.33337901864 207078_at MED6 MED6;NY-REN-28 10001 mediator of RNA polymerase II transcription, subunit 6 homolog (yeast) RNA polymerase II transcription factor activity (GO:0003702);receptor activity (GO:0004872);transcription regulator activity (GO:0030528) MED6 mediator (IPR007018) low -4.37223568295 201438_at COL6A3 COL6A3 1293 collagen, type VI, alpha 3 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);muscle development (GO:0007517);phosphate transport (GO:0006817);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Fibronectin, type III (IPR003961);Protease inhibitor I2, Kunitz metazoa (IPR002223);von Willebrand factor, type A (IPR002035) low -4.41666190433 206893_at SALL1 HSAL1;SALL1;TBS 6299 sal-like 1 (Drosophila) DNA binding (GO:0003677);embryogenesis and morphogenesis (GO:0007345);histogenesis and organogenesis (GO:0007397);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) low -4.719379835 215047_at BIA2 BIA2;DKFZp434C091 25893 BIA2 G-protein coupled receptor protein signaling pathway (GO:0007186);rhodopsin-like receptor activity (GO:0001584) B302, (SPRY)-like (IPR001870);Butyrophylin-like (IPR003879);Rhodopsin-like GPCR superfamily (IPR000276);SPRY-associated domain (IPR006574);SPla/RYanodine receptor SPRY (IPR003877) low -4.81994448825 221113_s_at WNT16 WNT16 51384 wingless-type MMTV integration site family, member 16 cell-cell signaling (GO:0007267);development (GO:0007275);extracellular matrix structural constituent (GO:0005201);frizzled-2 signaling pathway (GO:0007223);signal transducer activity (GO:0004871) Secreted growth factor Wnt protein (IPR005816);Wnt superfamily (IPR005817) low -5.05675024681 205402_x_at PRSS2 PRSS1;PRSS2;TRP1;TRY1;TRY2;TRY4;TRY8;TRYP1;TRYP2 5645 protease, serine, 2 (trypsin 2) calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) low -5.43522132664 213764_s_at MFAP5 MAGP2;MFAP5;MP25 8076 microfibrillar associated protein 5 extracellular matrix structural constituent (GO:0005201) Microfibril-associated glycoprotein (IPR008673) low -5.84229681768 221950_at EMX2 EMX2 2018 empty spiracles homolog 2 (Drosophila) DNA binding (GO:0003677);development (GO:0007275);transcription factor activity (GO:0003700) Bipartite nuclear localization signal (IPR001472);Helix-turn-helix motif, lambda-like repressor (IPR000047);Homeobox (IPR001356)