PC-42 p<0.000010 High/Low PC-42 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 7.45072687349 211735_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 7.26341205554 214387_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 7.19792957251 205982_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 6.06294070396 gnf1h05065_at gnf1h05065_at None None None None None high 5.94495202958 gnf1h04131_x_at gnf1h04131_x_at None None None None None high 5.87281634524 209810_at SFTPB PSP-B;SFTB3;SFTP3;SFTPB;SP-B 6439 surfactant, pulmonary-associated protein B histogenesis and organogenesis (GO:0007397);lipid metabolism (GO:0006629);organogenesis (GO:0009887);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sphingolipid metabolism (GO:0006665);surfactant activity (GO:0019214) Saposin (IPR008373);Saposin B (IPR008139);Saposin B subdomain (IPR008140);Saposin type A (IPR003119);Saposin-like type B, 1 (IPR007856);Saposin-like type B, 2 (IPR008138);Surfactant protein B (IPR008137) high 5.53551534393 214199_at SFTPD COLEC7;SFTP4;SFTPD;SP-D 6441 surfactant, pulmonary-associated protein D antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);bacterial binding (GO:0008367);heterophilic cell adhesion (GO:0007157);innate immune response (GO:0045087);lectin (GO:0005530);macrophage chemotaxis (GO:0048246);negative regulation of T-cell proliferation (GO:0042130);oxygen and reactive oxygen species metabolism (GO:0006800);phosphate transport (GO:0006817);receptor mediated endocytosis (GO:0006898);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sugar binding (GO:0005529);surfactant activity (GO:0019214);surfactant homeostasis (GO:0043129) C-type lectin (IPR001304) high 5.47835758615 gnf1h05066_x_at gnf1h05066_x_at None None None None None high 5.15758343582 215454_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 4.95738540327 213693_s_at MUC1 CD227;EMA;MUC1;PEM;PUM 4582 mucin 1, transmembrane actin binding (GO:0003779) Gonadotropin, beta chain (IPR001545);H+-transporting two-sector ATPase, alpha/beta subunit, central region (IPR000194);SEA (IPR000082) high 4.79945599477 gnf1h08686_at DKFZp434H2111 DKFZp434H2111 120892 hypothetical protein DKFZp434H2111 None Regulator of chromosome condensation, RCC1 (IPR000408) high 4.74431822912 217507_at SLC11A1 LSH;NRAMP;NRAMP1;SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 immune response (GO:0006955);iron ion transport (GO:0006826);response to bacteria (GO:0009617);response to pest/pathogen/parasite (GO:0009613);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215) Natural resistance-associated macrophage protein (IPR001046) high 4.6601409286 213317_at Hs.21103 None None MRNA; cDNA DKFZp564B076 (from clone DKFZp564B076) None None high 4.64080312472 gnf1h04196_x_at gnf1h04196_x_at None None None None None high 4.54341225507 212328_at KIAA1102 KIAA1102 22998 KIAA1102 protein actin binding (GO:0003779);smooth muscle contraction (GO:0006939) Calponin-like actin-binding (IPR001715);SM22/calponin (IPR003096);Zn-binding protein, LIM (IPR001781) high 4.508861599 37004_at SFTPB PSP-B;SFTB3;SFTP3;SFTPB;SP-B 6439 surfactant, pulmonary-associated protein B histogenesis and organogenesis (GO:0007397);lipid metabolism (GO:0006629);organogenesis (GO:0009887);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sphingolipid metabolism (GO:0006665);surfactant activity (GO:0019214) Saposin (IPR008373);Saposin B (IPR008139);Saposin B subdomain (IPR008140);Saposin type A (IPR003119);Saposin-like type B, 1 (IPR007856);Saposin-like type B, 2 (IPR008138);Surfactant protein B (IPR008137) high 4.50374282299 205569_at LAMP3 DC-LAMP;DCLAMP;LAMP;LAMP3;TSC403 27074 lysosomal-associated membrane protein 3 cell proliferation (GO:0008283);oncogenesis (GO:0007048) Lysosome-associated membrane glycoprotein (Lamp)/CD68 (IPR002000) high 4.47356797783 38691_s_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 4.47122059878 208470_s_at HPR HPR 3250 haptoglobin-related protein chymotrypsin activity (GO:0004263);hemoglobin binding (GO:0030492);peptidase activity (GO:0008233);plasma protein (GO:0005209);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Haptoglobin (IPR008292);Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003);Sushi domain/SCR domain/CCP module (IPR000436) high 4.42104537428 218835_at SFTPA2 COLEC5;SFTPA2;SP-A2;SPAII 6436 surfactant, pulmonary-associated protein A2 apolipoprotein (GO:0005320);heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);lipid transporter activity (GO:0005319);phosphate transport (GO:0006817);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sugar binding (GO:0005529);surfactant activity (GO:0019214) C-type lectin (IPR001304);Proline-rich region (IPR000694) high 4.25233614958 gnf1h04567_x_at gnf1h04567_x_at None None None None None high 4.2337961022 gnf1h04420_x_at gnf1h04420_x_at None None None None None high 4.13888776446 203108_at RAI3 GPRC5A;RAI3;RAIG1 9052 retinoic acid induced 3 G-protein coupled receptor activity (GO:0004930);metabotropic glutamate, GABA-B-like receptor activity (GO:0008067);receptor activity (GO:0004872);signal transduction (GO:0007165) G-protein coupled receptor family 3, metabotropic glutamate receptor-like (IPR000337) high 4.1314558127 214974_x_at CXCL5 CXCL5;ENA-78;SCYB5 6374 chemokine (C-X-C motif) ligand 5 cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);immune response (GO:0006955);inflammatory response (GO:0006954);positive regulation of cell proliferation (GO:0008284);signal transduction (GO:0007165) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 4.04415264356 gnf1h01101_at C20orf114 C20orf114;LPLUNC1;MGC14597 92747 chromosome 20 open reading frame 114 lipid binding (GO:0008289) Lipid-binding serum glycoprotein (IPR001124) high 4.03885151841 209904_at TNNC1 TNC;TNNC;TNNC1 7134 troponin C, slow calcium ion binding (GO:0005509);muscle development (GO:0007517) Calcium-binding EF-hand (IPR002048);Recoverin (IPR001125) high 4.02984788544 221911_at ETV1 ER81;ETV1 2115 ets variant gene 1 cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) Ets-domain (IPR000418);HSF/ETS DNA-binding (IPR002341);PEA3-type ETS-domain transcription factor, N-terminal (IPR006715) high 3.93574079268 206392_s_at RARRES1 RARRES1;TIG1 5918 retinoic acid receptor responder (tazarotene induced) 1 negative regulation of cell proliferation (GO:0008285);receptor activity (GO:0004872) Latexin (IPR009684) high 3.91422311547 220798_x_at FLJ11535 FLJ11535 79948 hypothetical protein FLJ11535 None Acid phosphatase/vanadium-dependent haloperoxidase (IPR008934);Phosphoesterase, PA-phosphatase related (IPR000326) high 3.89693388377 207850_at CXCL3 CINC-2b;CXCL3;GRO3;GROg;MIP-2b;MIP2B;SCYB3 2921 chemokine (C-X-C motif) ligand 3 G-protein coupled receptor protein signaling pathway (GO:0007186);chemokine activity (GO:0008009);chemotaxis (GO:0006935);cytokine activity (GO:0005125);immune response (GO:0006955);inflammatory response (GO:0006954) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 3.89467671561 210096_at CYP4B1 CYP4B1;P-450HP 1580 cytochrome P450, family 4, subfamily B, polypeptide 1 cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);monooxygenase activity (GO:0004497);oxygen binding (GO:0019825) Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group II (IPR002402);E-class P450, group IV (IPR002403) low -5.05218808557 203078_at CUL2 CUL2 8453 cullin 2 negative regulation of cell proliferation (GO:0008285);oncogenesis (GO:0007048);tumor suppressor (GO:0008181) Bipartite nuclear localization signal (IPR001472);Cullin (IPR001373) low -5.10038125891 217536_x_at Hs.314534 None None Transcribed sequence with weak similarity to protein ref:NP_060265.1 (H.sapiens) hypothetical protein FLJ20378 [Homo sapiens] None None low -5.22432351812 203767_s_at STS ARSC;ARSC1;ASC;SSDD;STS 412 steroid sulfatase (microsomal), arylsulfatase C, isozyme S calcium ion binding (GO:0005509);hydrolase activity (GO:0016787);metabolism (GO:0008152);pregnancy (GO:0007565);steroid catabolism (GO:0006706);steryl-sulfatase activity (GO:0004773) Sulfatase (IPR000917) low -5.2609892242 209351_at KRT14 CK14;EBS3;EBS4;K14;KRT14 3861 keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) biological_process unknown (GO:0000004);structural constituent of cytoskeleton (GO:0005200);structural constituent of epidermis (GO:0030280) 14-3-3 protein (IPR000308);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Tachykinin/Neurokinin (IPR002040) low -5.82245243025 211430_s_at IGHG1 IGHG1 3500 immunoglobulin heavy constant gamma 1 (G1m marker) antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -7.01690904504 217022_s_at MGC27165 MGC27165 283650 hypothetical protein MGC27165 None Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006)