PC-46 p<0.000010 High/Low PC-46 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 7.84503704607 212768_s_at GW112 GC1;GW112 10562 differentially expressed in hematopoietic lineages None Latrophilin receptor (IPR003924);Olfactomedin-like (IPR003112) high 6.24713690799 205837_s_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) high 6.09171559896 205862_at GREB1 GREB1;KIAA0575 9687 GREB1 protein biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) None high 5.85100709252 206676_at CEACAM8 CD66b;CD67;CEACAM8;CGM6;NCA-95 1088 carcinoembryonic antigen-related cell adhesion molecule 8 immune response (GO:0006955);tumor antigen (GO:0008222) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 5.64632467688 211303_x_at PSMAL/GCP III PSMAL/GCP III 219595 prostate-specific membrane antigen-like protein peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508) Peptidase M28 (IPR007484);Transferrin receptor-like dimerisation domain (IPR007365) high 5.24989641749 204848_x_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 5.23002770329 204737_s_at MYH7 CMH1;MYH7;MYHCB 4625 myosin, heavy polypeptide 7, cardiac muscle, beta ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);microfilament motor activity (GO:0000146);motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928);Tropomyosin (IPR000533) high 5.19225161033 214712_at AK023827 None None None None None high 5.10691243754 210612_s_at SYNJ2 INPP5H;SYNJ2 8871 synaptojanin 2 RNA binding (GO:0003723);hydrolase activity (GO:0016787);inositol-polyphosphate 5-phosphatase activity (GO:0004445);inositol/phosphatidylinositol phosphatase activity (GO:0004437);nucleic acid binding (GO:0003676);phosphoinositide 5-phosphatase activity (GO:0004439);signal transduction (GO:0007165) Endonuclease/exonuclease/phosphatase (IPR005135);Inositol polyphosphate related phosphatase (IPR000300);Proline-rich region (IPR000694);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504);Synaptojanin, N-terminal (IPR002013) high 5.02089287506 214475_x_at CAPN3 CANP3;CANPL3;CAPN3;LGMD2;LGMD2A;MGC10767;MGC11121;MGC14344;MGC4403;nCL-1;p94 825 calpain 3, (p94) calcium ion binding (GO:0005509);calpain activity (GO:0004198);cysteine-type peptidase activity (GO:0008234);hydrolase activity (GO:0016787);muscle development (GO:0007517);proteolysis and peptidolysis (GO:0006508);signal transducer activity (GO:0004871) Calcium-binding EF-hand (IPR002048);Peptidase C2, calpain (IPR001300);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 4.80249595244 205040_at ORM1 AGP-A;AGP1;ORM;ORM1 5004 orosomucoid 1 acute-phase response (GO:0006953);acute-phase response protein activity (GO:0003794);inflammatory response (GO:0006954);plasma glycoprotein (GO:0005211);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-acid glycoprotein (IPR001500);Bipartite nuclear localization signal (IPR001472);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) high 4.77113410939 210387_at HIST1H2BG H2B.1A;H2B/a;H2B/g;H2BFA;H2BFG;HIST1H2BF;HIST1H2BG 8339 histone 1, H2bg DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H2B (IPR000558);Histone core (IPR007125);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 4.67912969078 211743_s_at PRG2 BMPG;MBP;MGC14537;PRG2 5553 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) heparin binding (GO:0008201);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);inflammatory response (GO:0006954);sugar binding (GO:0005529);xenobiotic metabolism (GO:0006805) C-type lectin (IPR001304);Eosinophil major basic protein (IPR002352) high 4.66010171078 206143_at SLC26A3 CLD;DRA;SLC26A3 1811 solute carrier family 26, member 3 anion transport (GO:0006820);antiport (GO:0015982);antiporter activity (GO:0015297);excretion (GO:0007588);sulfate porter activity (GO:0008271);sulfate transport (GO:0008272);transcription cofactor activity (GO:0003712);transcription factor activity (GO:0003700);transport (GO:0006810);transporter activity (GO:0005215);tumor suppressor (GO:0008181) Bipartite nuclear localization signal (IPR001472);Sulfate transporter/antisigma-factor antagonist STAS (IPR002645);Sulphate transporter (IPR001902) high 4.62786981304 210297_s_at MSMB IGBF;MSMB;MSP;MSPB;PN44;PRPS;PSP;PSP-94;PSP57;PSP94 4477 microseminoprotein, beta- biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) Beta-microseminoprotein (IPR008735) high 4.58742022503 215779_s_at HIST1H2BG H2B.1A;H2B/a;H2B/g;H2BFA;H2BFG;HIST1H2BF;HIST1H2BG 8339 histone 1, H2bg DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H2B (IPR000558);Histone core (IPR007125);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 4.55802563318 219466_s_at APOA2 APOA2 336 apolipoprotein A-II glucose metabolism (GO:0006006);high-density lipoprotein (GO:0005321);lipid binding (GO:0008289);lipid catabolism (GO:0016042);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);neutrophil activation (GO:0042119);protein heterodimerization activity (GO:0046982);protein homodimerization activity (GO:0042803);response to glucose stimulus (GO:0009749) Apolipoprotein A-II (ApoA-II) (IPR006801) high 4.55469417156 202018_s_at LTF HLF2;LTF 4057 lactotransferrin ferric iron binding (GO:0008199);humoral immune response (GO:0006959);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);serine-type endopeptidase activity (GO:0004252);transport (GO:0006810);xenobiotic metabolism (GO:0006805) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 4.54202553148 213684_s_at LIM ENH;LIM 10611 LIM protein (similar to rat protein kinase C-binding enigma) kinase activity (GO:0016301);protein binding (GO:0005515);protein kinase C binding (GO:0005080);signal transduction (GO:0007165) PDZ/DHR/GLGF domain (IPR001478);Zn-binding protein, LIM (IPR001781) high 4.45639862141 204463_s_at EDNRA EDNRA;ETA;ETRA 1909 endothelin receptor type A G-protein coupled receptor protein signaling pathway (GO:0007186);cell proliferation (GO:0008283);endothelin receptor activity (GO:0004962);phosphatidylinositol-4,5-bisphosphate hydrolysis (GO:0007203);phosphoinositide phospholipase C activity (GO:0004435);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584);signal transduction (GO:0007165);smooth muscle contraction (GO:0006939) Endothelin A receptor (IPR002175);Endothelin receptor (IPR000499);Rhodopsin-like GPCR superfamily (IPR000276) high 4.39351830382 gnf1h05769_at POTE15 POTE15 339010 protein expressed in prostate, ovary, testis, and placenta None None high 4.36704867096 203948_s_at MPO MPO 4353 myeloperoxidase calcium ion binding (GO:0005509);chromatin binding (GO:0003682);defense response (GO:0006952);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);response to oxidative stress (GO:0006979) Animal haem peroxidase (IPR002007);Haem peroxidase, plant/fungal/bacterial (IPR002016) high 4.31761907175 203872_at ACTA1 ACTA;ACTA1;ASMA;NEM1;NEM2 58 actin, alpha 1, skeletal muscle motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);structural constituent of cytoskeleton (GO:0005200) Actin (IPR004001);Actin/actin-like (IPR004000) high 4.28878860034 205033_s_at DEFA1 DEF1;DEFA1;HNP-1;HP-1;MRS 1667 defensin, alpha 1, myeloid-related sequence antifungal peptide activity (GO:0003799);antimicrobial peptide activity (GO:0003795);chemotaxis (GO:0006935);defense response (GO:0006952);defense response to fungi (GO:0050832);immune response (GO:0006955);response to pest/pathogen/parasite (GO:0009613);xenobiotic metabolism (GO:0006805) Alpha defensin (IPR006081);Defensin propeptide (IPR002366);Mammalian defensin (IPR006080) high 4.23363596831 206117_at TPM1 CMH3;TMSA;TPM1 7168 tropomyosin 1 (alpha) actin binding (GO:0003779);muscle development (GO:0007517);regulation of heart rate (GO:0008016);structural constituent of cytoskeleton (GO:0005200);structural constituent of muscle (GO:0008307) Beta-ketoacyl synthase (IPR000794);SF_assemblin (IPR008374);Tropomyosin (IPR000533) low -4.41253395935 gnf1h08879_at LOC375616 LOC375616 375616 kielin-like None Aldo/keto reductase (IPR001395) low -4.44503389838 gnf1h02217_s_at CEP1 CEP1;CEP110;FAN 11064 centrosomal protein 1 RNA polymerase II transcription factor activity (GO:0003702) Proline-rich region (IPR000694) low -4.49857991447 202238_s_at NNMT NNMT 4837 nicotinamide N-methyltransferase methyltransferase activity (GO:0008168);nicotinamide N-methyltransferase activity (GO:0008112);transferase activity (GO:0016740) Generic methyltransferase (IPR001601);Methyltransferase, NNMT/PNMT/TEMT (IPR000940) low -4.55436171334 216080_s_at FADS3 BC269730_1;CYB5RP;FADS3;LLCDL3 3995 fatty acid desaturase 3 fatty acid desaturation (GO:0006636);oxidoreductase activity (GO:0016491) ARM repeat fold (IPR008938);Cytochrome b5 (IPR001199);Fatty acid desaturase (IPR005804);Fatty acid desaturase subdomain (IPR010257) low -4.57830988121 gnf1h04445_at FLJ22344 FLJ22344 79772 hypothetical protein FLJ22344 None C2 calcium/lipid-binding domain, CaLB (IPR008973);C2 domain (IPR000008) low -5.0302870247 gnf1h04269_at gnf1h04269_at None None None None None low -5.42866586904 gnf1h00739_at MGC13272 MGC13272 84315 hypothetical protein MGC13272 molecular_function unknown (GO:0005554);transport (GO:0006810) Yeast 73.5kDa hypothetical-related protein (IPR004353) low -6.39094607876 208791_at CLU APOJ;CLI;CLU;MGC24903;SGP-2;SGP2;SP-40;TRPM-2;TRPM2 1191 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) apoptosis (GO:0006915);cell death (GO:0008219);fertilization (sensu Animalia) (GO:0007338);lipid metabolism (GO:0006629);plasma glycoprotein (GO:0005211) Bipartite nuclear localization signal (IPR001472);Clusterin (IPR000753)