PC-9 p<0.001000 High/Low PC-9 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 19.7365058092 209116_x_at HBB HBB 3043 hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 18.432173401 211699_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 18.3804022551 209301_at CA2 CA-II;CA2 760 carbonic anhydrase II carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) high 17.1984791646 217414_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.9830970517 209458_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.9020259661 204018_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.6596642493 gnf1h04131_x_at gnf1h04131_x_at None None None None None high 16.6084120658 gnf1h04130_x_at gnf1h04130_x_at None None None None None high 16.5721516104 211745_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.4595999748 gnf1h04129_x_at gnf1h04129_x_at None None None None None high 16.327864071 gnf1h08167_s_at gnf1h08167_s_at None None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) high 16.0750895461 gnf1h05066_x_at gnf1h05066_x_at None None None None None high 16.0549282744 209930_s_at NFE2 NF-E2;NFE2;p45 4778 nuclear factor (erythroid-derived 2), 45kDa circulation (GO:0008015);development (GO:0007275);hemostasis (GO:0007599);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);translation regulator activity (GO:0045182) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Eukaryotic transcription factor, DNA-binding (IPR008917);Proline-rich region (IPR000694) high 15.6075336177 204848_x_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 15.2303010272 214414_x_at HBA2 HBA1;HBA2 3040 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 15.163647107 211696_x_at HBB HBB 3043 hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 14.7033599431 202219_at SLC6A8 CRTR;CT1;SLC6A8 6535 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 creatine transport (GO:0015881);creatine transporter activity (GO:0005308);creatine:sodium symporter activity (GO:0005309);muscle contraction (GO:0006936);neurotransmitter transport (GO:0006836);neurotransmitter:sodium symporter activity (GO:0005328);small molecule transport (GO:0006832);symporter activity (GO:0015293);transport (GO:0006810) Creatine transporter (IPR002984);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504);Sodium:neurotransmitter symporter (IPR000175) high 14.6633372367 217232_x_at HBB HBB 3043 hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 14.5868958223 209605_at TST MGC19578;RDS;TST 7263 thiosulfate sulfurtransferase (rhodanese) cyanate catabolism (GO:0009440);sulfate transport (GO:0008272);thiosulfate sulfurtransferase activity (GO:0004792);transferase activity (GO:0016740) Rhodanese-like (IPR001763);Thiosulfate sulfurtransferase (IPR001307) high 14.5436290959 209555_s_at CD36 CD36;FAT;GP3B;GP4;GPIV;PASIV;SCARB3 948 CD36 antigen (collagen type I receptor, thrombospondin receptor) blood coagulation (GO:0007596);cell adhesion (GO:0007155);fatty acid metabolism (GO:0006631);protein binding (GO:0005515);receptor activity (GO:0004872);transport (GO:0006810) Adhesion molecule CD36 (IPR005428);CD36 antigen (IPR002159) high 14.1651076337 206834_at HBD HBD 3045 hemoglobin, delta globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 14.1248331414 gnf1h04566_at gnf1h04566_at None None None None None high 14.0708153118 209522_s_at CRAT CAT1;CRAT 1384 carnitine acetyltransferase acyl-CoA metabolism (GO:0006637);acyltransferase activity (GO:0008415);carnitine O-acetyltransferase activity (GO:0004092);energy derivation by oxidation of organic compounds (GO:0015980);energy pathways (GO:0006091);transferase activity (GO:0016740);transport (GO:0006810) Acyltransferase ChoActase/COT/CPT (IPR000542) high 13.9520519775 gnf1h04420_x_at gnf1h04420_x_at None None None None None high 13.8214432912 206488_s_at CD36 CD36;FAT;GP3B;GP4;GPIV;PASIV;SCARB3 948 CD36 antigen (collagen type I receptor, thrombospondin receptor) blood coagulation (GO:0007596);cell adhesion (GO:0007155);fatty acid metabolism (GO:0006631);protein binding (GO:0005515);receptor activity (GO:0004872);transport (GO:0006810) Adhesion molecule CD36 (IPR005428);CD36 antigen (IPR002159) high 13.7346148828 213515_x_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 13.699999856 gnf1h05065_at gnf1h05065_at None None None None None high 13.5816210869 201743_at CD14 CD14;NDUFA2 929 CD14 antigen GPI-anchored membrane-bound receptor (GO:0015025);NADH dehydrogenase (ubiquinone) activity (GO:0008137);NADH dehydrogenase activity (GO:0003954);antibacterial peptide activity (GO:0003797);apoptosis (GO:0006915);cell surface receptor linked signal transduction (GO:0007166);energy pathways (GO:0006091);immune response (GO:0006955);inflammatory response (GO:0006954);oxidoreductase activity (GO:0016491);peptidoglycan receptor activity (GO:0016019);phagocytosis (GO:0006909) Mitochondrial ribosome (IPR007741) high 13.0695559772 210613_s_at SYNGR1 MGC:1939;SYNGR1 9145 synaptogyrin 1 transport (GO:0006810);transporter activity (GO:0005215) Marvel (IPR008253);TonB-dependent receptor (IPR000531) high 13.0646142752 204959_at MNDA MNDA 4332 myeloid cell nuclear differentiation antigen DNA binding (GO:0003677);cellular defense response (GO:0006968);translation regulator activity (GO:0045182) Bipartite nuclear localization signal (IPR001472);HIN-200/IF120x domain (IPR004021);Pyrin domain (IPR004020) high 12.8255046353 gnf1h04567_x_at gnf1h04567_x_at None None None None None high 12.5381930517 202917_s_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 6279 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 12.4658305743 206380_s_at PFC BFD;PFC;PFD;PROPERDIN 5199 properdin P factor, complement antibacterial peptide activity (GO:0003797);complement activity (GO:0003811);defense response to bacteria (GO:0042742);immune response (GO:0006955);plasma glycoprotein (GO:0005211) Surface protein from Gram-positive cocci, anchor region (IPR001899) high 12.3851147193 215047_at BIA2 BIA2;DKFZp434C091 25893 BIA2 G-protein coupled receptor protein signaling pathway (GO:0007186);rhodopsin-like receptor activity (GO:0001584) B302, (SPRY)-like (IPR001870);Butyrophylin-like (IPR003879);Rhodopsin-like GPCR superfamily (IPR000276);SPRY-associated domain (IPR006574);SPla/RYanodine receptor SPRY (IPR003877) high 12.2724707935 205950_s_at CA1 CA1 759 carbonic anhydrase I carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) high 12.2346984373 203535_at S100A9 60B8AG;CAGB;CFAG;CGLB;L1AG;LIAG;MAC387;MIF;MRP14;NIF;P14;S100A9 6280 S100 calcium binding protein A9 (calgranulin B) calcium ion binding (GO:0005509);cell-cell signaling (GO:0007267);inflammatory response (GO:0006954);signal transducer activity (GO:0004871) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 12.1162005955 210122_at PRM2 PRM2 5620 protamine 2 DNA binding (GO:0003677);DNA packaging (GO:0006323);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);spermatogenesis (GO:0007283) Bipartite nuclear localization signal (IPR001472);Protamine 2, PRM2 (IPR000492) high 12.0997567985 205592_at SLC4A1 AE1;BND3;CD233;EMPB3;EPB3;RTA1A;SLC4A1;WD1 6521 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) anion exchanger activity (GO:0015380);anion transport (GO:0006820);anion transporter activity (GO:0008509);cell ion homeostasis (GO:0006873);inorganic anion exchanger activity (GO:0005452) Anion exchange protein (IPR001717);Anion exchanger, isoform 1 (IPR002977);HCO3- transporter (IPR003020) high 11.9745434096 202201_at BLVRB BLVRB;BVRB;FLR 645 biliverdin reductase B (flavin reductase (NADPH)) biliverdin reductase activity (GO:0004074);flavin reductase activity (GO:0042602);oxidoreductase activity (GO:0016491) None high 11.9496785948 204419_x_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 11.8137285774 211821_x_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) high 11.7830955841 210215_at TFR2 HFE3;TFR2 7036 transferrin receptor 2 iron ion transport (GO:0006826);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);transferrin receptor activity (GO:0004998) Peptidase M28 (IPR007484);Protease-associated PA (IPR003137);Transferrin receptor-like dimerisation domain (IPR007365) high 11.7658877885 205237_at FCN1 FCN1;FCNM 2219 ficolin (collagen/fibrinogen domain containing) 1 antigen binding (GO:0003823);antimicrobial humoral response (sensu Protostomia) (GO:0006960);calcium ion binding (GO:0005509);heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);opsonin activity (GO:0008229);phosphate transport (GO:0006817);plasma protein (GO:0005209);sugar binding (GO:0005529) Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) high 11.7622801593 gnf1h09294_s_at HBG1 HBG1;HBGA;HBGR 3047 hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 11.7117470514 202768_at FOSB FOSB;GOS3;GOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B DNA binding (GO:0003677);behavior (GO:0007610);development (GO:0007275);transcription factor binding (GO:0008134) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Fos transforming protein (IPR000837);Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209);Proline-rich region (IPR000694) high 11.6845743761 211560_s_at ALAS2 ALAS2;ANH1;ASB 212 aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) 5-aminolevulinate synthase activity (GO:0003870);acyltransferase activity (GO:0008415);biosynthesis (GO:0009058);heme biosynthesis (GO:0006783);transaminase activity (GO:0008483);transferase activity (GO:0016740) Aminolevulinic acid synthase (IPR003408);Aminotransferase, class I and II (IPR004839);Aminotransferase, class-II (IPR001917) high 11.6663090906 217202_s_at 217202_s_at None None None None None high 11.6295993406 gnf1h04196_x_at gnf1h04196_x_at None None None None None high 11.5743607476 205391_x_at ANK1 ANK;ANK1;SPH1;SPH2 286 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 11.5692838331 219672_at ERAF AHSP;EDRF;ERAF 51327 erythroid associated factor chaperone activity (GO:0003754);hemoglobin binding (GO:0030492);hemoglobin metabolism (GO:0020027);hemopoiesis (GO:0030097) None high 11.547860924 214433_s_at SELENBP1 FLJ13813;LPSB;SELENBP1;SP56;hSBP;hSP56 8991 selenium binding protein 1 selenium binding (GO:0008430) 56kDa selenium binding (IPR008826) high 11.5197872036 220744_s_at WDR10 DKFZp434K016;FLJ00025;FLJ10897;FLJ11093;SPG;WDR10;WDR10p;WDR140 55764 WD repeat domain 10 None TPR-like (IPR008941) high 11.5036762802 206145_at RHAG RH2;RH50A;RHAG 6005 Rhesus blood group-associated glycoprotein ammonium transport (GO:0015696);ammonium transporter activity (GO:0008519);ankyrin binding (GO:0030506);blood group antigen (GO:0005555);circulation (GO:0008015);protein complex assembly (GO:0006461);transport (GO:0006810) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 11.4499268708 205262_at KCNH2 ERG1;HERG;HERG1;KCNH2;Kv11.1;LQT2 3757 potassium voltage-gated channel, subfamily H (eag-related), member 2 DNA binding (GO:0003677);cation transport (GO:0006812);circulation (GO:0008015);delayed rectifier potassium channel activity (GO:0005251);muscle contraction (GO:0006936);perception of sound (GO:0007605);potassium channel activity (GO:0005267);potassium ion transport (GO:0006813);regulation of heart rate (GO:0008016);two-component sensor molecule activity (GO:0000155);two-component signal transduction system (phosphorelay) (GO:0000160);voltage-gated potassium channel activity (GO:0005249) Cation channel, non-ligand gated (IPR005820);Cyclic nucleotide-binding domain (IPR000595);EAG/ELK/ERG potassium channel (IPR003938);Erg channel (IPR003967);Ion transport protein (IPR005821);K+ channel, pore region (IPR001622);PAS (IPR000014);PAS-associated, C-terminal (IPR000700) high 11.4372211725 202087_s_at CTSL CATL;CTSL;MEP 1514 cathepsin L cathepsin L activity (GO:0004217);cysteine-type endopeptidase activity (GO:0004197);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508) Peptidase C1A, papain (IPR000668);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 11.4102634356 210746_s_at EPB42 EPB42 2038 erythrocyte membrane protein band 4.2 ATP binding (GO:0005524);cellular morphogenesis (GO:0000902);peptide cross-linking (GO:0018149);structural constituent of cytoskeleton (GO:0005200) Immunoglobulin-like (IPR007110);Protein-glutamine gamma-glutamyltransferase (IPR001102);Transglutaminase, C-terminal (IPR008958);Transglutaminase-like domain (IPR002931) high 11.403448145 204122_at TYROBP DAP12;KARAP;PLOSL;TYROBP 7305 TYRO protein tyrosine kinase binding protein cellular defense response (GO:0006968);intracellular signaling cascade (GO:0007242);receptor activity (GO:0004872);receptor signaling protein activity (GO:0005057);signal transduction (GO:0007165) None high 11.3773751577 200648_s_at GLUL GLNS;GLUL 2752 glutamate-ammonia ligase (glutamine synthase) glutamate-ammonia ligase activity (GO:0004356);glutamine biosynthesis (GO:0006542);ligase activity (GO:0016874);nitrogen fixation (GO:0009399) Glutamine synthetase, beta-Grasp domain (IPR008147);Glutamine synthetase, catalytic domain (IPR008146) high 11.2224829279 gnf1h00293_at HEMGN EDAG;EDAG-1;HEMGN 55363 hemogen None Bipartite nuclear localization signal (IPR001472) high 11.1887962534 221210_s_at NPL C1orf13;NPL;NPL1;c112 80896 N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) None Dihydrodipicolinate synthetase (IPR002220) high 11.1722714729 204466_s_at SNCA NACP;PARK1;PD1;SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) pathogenesis (GO:0009405);structural molecule activity (GO:0005198) Alpha-synuclein (IPR002460);Gamma-synuclein (IPR002462);Synuclein (IPR001058) high 11.1379143274 201360_at CST3 AD8;CST3 1471 cystatin C (amyloid angiopathy and cerebral hemorrhage) cysteine protease inhibitor activity (GO:0004869) Cystatin C/M (IPR003243);Cysteine protease inhibitor (IPR000010) high 11.1291472333 205200_at TNA TNA 7123 tetranectin (plasminogen binding protein) heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);skeletal development (GO:0001501);sugar binding (GO:0005529) C-type lectin (IPR001304);Pancreatitis-associated protein (IPR003990) high 11.0749842912 221841_s_at KLF4 EZF;GKLF;KLF4 9314 Kruppel-like factor 4 (gut) negative regulation of cell proliferation (GO:0008285);nucleic acid binding (GO:0003676);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcriptional activator activity (GO:0016563);transcriptional repressor activity (GO:0016564);zinc ion binding (GO:0008270) Proline-rich region (IPR000694);Zn-finger, C2H2 type (IPR007087) high 11.0427871744 217977_at SEPX1 HSPC270;MGC3344;SELR;SELX;SEPX1 51734 selenoprotein X, 1 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554);oxidoreductase activity (GO:0016491);selenium binding (GO:0008430) Protein of unknown function DUF25 (IPR002579) high 11.0264053891 203381_s_at APOE APOE 348 apolipoprotein E antioxidant activity (GO:0016209);apolipoprotein E receptor binding (GO:0050749);beta-amyloid binding (GO:0001540);cholesterol homeostasis (GO:0042632);cholesterol metabolism (GO:0008203);circulation (GO:0008015);cytoskeleton organization and biogenesis (GO:0007010);development (GO:0007275);heparin binding (GO:0008201);immune response (GO:0006955);intracellular transport (GO:0046907);learning and/or memory (GO:0007611);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);low-density lipoprotein receptor binding (GO:0050750);plasma protein (GO:0005209);receptor binding (GO:0005102);response to reactive oxygen species (GO:0000302);tau protein binding (GO:0048156) Apolipoprotein A1/A4/E (IPR000074) high 10.9899900283 210044_s_at LYL1 LYL1 4066 lymphoblastic leukemia derived sequence 1 DNA binding (GO:0003677);cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048) Basic helix-loop-helix dimerization domain bHLH (IPR001092);Proline-rich region (IPR000694) high 10.9059983168 211003_x_at TGM2 TGC;TGM2 7052 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) acyltransferase activity (GO:0008415);biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);molecular_function unknown (GO:0005554);peptide cross-linking (GO:0018149);protein modification (GO:0006464);protein-glutamine gamma-glutamyltransferase activity (GO:0003810);transferase activity (GO:0016740) Immunoglobulin-like (IPR007110);Protein-glutamine gamma-glutamyltransferase (IPR001102);Transglutaminase, C-terminal (IPR008958);Transglutaminase-like domain (IPR002931) high 10.8939713105 205838_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) high 10.8691860114 gnf1h05211_x_at gnf1h05211_x_at None None None None None high 10.8638230852 205382_s_at DF ADN 1675 D component of complement (adipsin) RNA polymerase II transcription mediator activity (GO:0016455);androgen receptor signaling pathway (GO:0030521);chymotrypsin activity (GO:0004263);complement factor D activity (GO:0003817);hydrolase activity (GO:0016787);ligand-dependent nuclear receptor transcription coactivator activity (GO:0030374);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);serine-type peptidase activity (GO:0008236);thyroid hormone receptor binding (GO:0046966);transcription coactivator activity (GO:0003713);transcription cofactor activity (GO:0003712);transcription from Pol II promoter (GO:0006366);transcriptional activator activity (GO:0016563);trypsin activity (GO:0004295);vitamin D receptor binding (GO:0042809) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 10.860753363 215495_s_at SAMD4 DKFZp434H0350;KIAA1053;SAMD4 23034 sterile alpha motif domain containing 4 None Sterile alpha motif SAM (IPR001660) high 10.8553648665 218450_at HEBP1 HBP;HEBP;HEBP1 50865 heme binding protein 1 binding (GO:0005488);circadian rhythm (GO:0007623) SOUL heme-binding protein (IPR006917) high 10.8276016239 221845_s_at SKD3 SKD3 81570 suppressor of potassium transport defect 3 ATP binding (GO:0005524);nucleotide binding (GO:0000166) AAA ATPase (IPR003593);Chaperonin clpA/B (IPR001270) high 10.8234172185 gnf1h05210_at gnf1h05210_at None None None None None high 10.7790132973 200736_s_at GPX1 GPX1;GSHPX1;MGC14399 2876 glutathione peroxidase 1 glutathione peroxidase activity (GO:0004602);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);peroxidase reaction (GO:0006804);response to oxidative stress (GO:0006979);selenium binding (GO:0008430) Glutathione peroxidase (IPR000889) high 10.7771220034 208146_s_at CPVL CPVL;HVLP;MGC10029 54504 carboxypeptidase, vitellogenic-like carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);serine carboxypeptidase activity (GO:0004185) Beta and gamma crystallin (IPR001064);Esterase/lipase/thioesterase (IPR000379);Peptidase S10, serine carboxypeptidase (IPR001563) high 10.7610169278 203186_s_at S100A4 18A2;42A;CAPL;MTS1;P9KA;PEL98;S100A4 6275 S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) calcium ion binding (GO:0005509);invasive growth (GO:0007125) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 10.7181289842 200839_s_at CTSB APPS;CPSB;CTSB 1508 cathepsin B cathepsin B activity (GO:0004213);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508) Peptidase C1A, papain (IPR000668);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 10.7113435517 208353_x_at ANK1 ANK;ANK1;SPH1;SPH2 286 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 10.6051585716 211820_x_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) high 10.5456904346 211429_s_at SERPINA1 A1A;A1AT;AAT;PI1;SERPINA1 5265 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 acute-phase response (GO:0006953);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibititor I4, serpin (IPR000215) high 10.5247568337 201105_at LGALS1 FLJ21318;GBP;LGALS1;PDXP;PLP;SH3BP1;dJ37E16;dJ37E16.5 3956 lectin, galactoside-binding, soluble, 1 (galectin 1) apoptosis (GO:0006915);galactose binding (GO:0005534);galactose binding lectin (GO:0005531);heterophilic cell adhesion (GO:0007157);hydrolase activity (GO:0016787);lectin (GO:0005530);metabolism (GO:0008152);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871);sugar binding (GO:0005529) 2-phosphoglycolate phosphatase, eukaryotic (IPR006349);Concanavalin A-like lectin/glucanase (IPR008985);Galectin, galactose-binding lectin (IPR001079);HAD-superfamily hydrolase, subfamily IIA (IPR006357);Haloacid dehalogenase-like hydrolase (IPR005834);Proline-rich region (IPR000694);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198) high 10.4790477099 gnf1h04195_at gnf1h04195_at None None None None None high 10.4755146608 210844_x_at CTNNA1 CAP102;CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);structural molecule activity (GO:0005198) Alpha-catenin (IPR001033);Vinculin (IPR000633);Vinculin/alpha-catenin (IPR006077) high 10.4717285468 218487_at ALAD ALAD;ALADH;MGC5057 210 aminolevulinate, delta-, dehydratase catalytic activity (GO:0003824);heme biosynthesis (GO:0006783);lyase activity (GO:0016829);porphobilinogen synthase activity (GO:0004655) Delta-aminolevulinic acid dehydratase (IPR001731) high 10.4708905732 212473_s_at MICAL2 KIAA0750;MICAL2 9645 flavoprotein oxidoreductase MICAL2 aromatic compound metabolism (GO:0006725);electron transport (GO:0006118);monooxygenase activity (GO:0004497) Aromatic-ring hydroxylase (IPR003042);Calponin-like actin-binding (IPR001715);Monooxygenase, FAD-binding (IPR002938);Zn-binding protein, LIM (IPR001781) high 10.4588970109 221932_s_at C14orf87 C14orf87;FLB4739;PR01238 51218 chromosome 14 open reading frame 87 None Glutaredoxin-related protein (IPR004480) high 10.4493405071 204619_s_at CSPG2 CSPG2;VERSICAN 1462 chondroitin sulfate proteoglycan 2 (versican) calcium ion binding (GO:0005509);cell adhesion (GO:0007155);chondroitin sulfate proteoglycan (GO:0005204);development (GO:0007275);glycosaminoglycan binding (GO:0005539);heterophilic cell adhesion (GO:0007157);hyaluronic acid binding (GO:0005540);lectin (GO:0005530);proteoglycan (GO:0005203);sugar binding (GO:0005529) C-type lectin (IPR001304);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436);Type II EGF-like signature (IPR001438);Type II antifreeze protein (IPR002353) high 10.4354164497 218831_s_at FCGRT FCGRT;FCRN 2217 Fc fragment of IgG, receptor, transporter, alpha IgG binding (GO:0019864);immune response (GO:0006955);pregnancy (GO:0007565);receptor activity (GO:0004872) Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Major histocompatibility complex protein, class I (IPR001039) high 10.4273965545 207827_x_at SNCA NACP;PARK1;PD1;SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) pathogenesis (GO:0009405);structural molecule activity (GO:0005198) Alpha-synuclein (IPR002460);Gamma-synuclein (IPR002462);Synuclein (IPR001058) high 10.4073842734 201041_s_at DUSP1 CL100;DUSP1;HVH1;MKP-1;PTPN10 1843 dual specificity phosphatase 1 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);non-membrane spanning protein tyrosine phosphatase activity (GO:0004726);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein tyrosine/serine/threonine phosphatase activity (GO:0008138);response to oxidative stress (GO:0006979) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Protein tyrosine phosphatase, catalytic region (IPR003595);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 10.361619136 213275_x_at BE875786 None None None None None high 10.3497689483 216317_x_at RHCE RH30A;RHC;RHCE;RHE;RHIXB;RHPI;Rh4;RhVI;RhVIII 6006 Rhesus blood group, CcEe antigens ammonium transporter activity (GO:0008519);blood group antigen (GO:0005555);transport (GO:0006810);transporter activity (GO:0005215) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 10.3472963643 204249_s_at LMO2 LMO2;RBTN2;RBTNL1;RHOM2;TTG2 4005 LIM domain only 2 (rhombotin-like 1) cell growth and/or maintenance (GO:0008151);development (GO:0007275);oncogenesis (GO:0007048) Zn-binding protein, LIM (IPR001781) high 10.3294956743 220690_s_at DKFZp566O084 CGI-93;DKFZp566O084;MGC8916 25979 DKFZP566O084 protein metabolism (GO:0008152);oxidoreductase activity (GO:0016491) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (IPR003560);Glucose/ribitol dehydrogenase (IPR002347);Short-chain dehydrogenase/reductase SDR (IPR002198) high 10.3057461781 219594_at NINJ2 NINJ2 4815 ninjurin 2 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);neurogenesis (GO:0007399);neuronal cell adhesion (GO:0007158) Ninjurin (IPR007007) high 10.2853365343 215001_s_at GLUL GLNS;GLUL 2752 glutamate-ammonia ligase (glutamine synthase) glutamate-ammonia ligase activity (GO:0004356);glutamine biosynthesis (GO:0006542);ligase activity (GO:0016874);nitrogen fixation (GO:0009399) Glutamine synthetase, beta-Grasp domain (IPR008147);Glutamine synthetase, catalytic domain (IPR008146) high 10.2836738559 215646_s_at CSPG2 CSPG2;VERSICAN 1462 chondroitin sulfate proteoglycan 2 (versican) calcium ion binding (GO:0005509);cell adhesion (GO:0007155);chondroitin sulfate proteoglycan (GO:0005204);development (GO:0007275);glycosaminoglycan binding (GO:0005539);heterophilic cell adhesion (GO:0007157);hyaluronic acid binding (GO:0005540);lectin (GO:0005530);proteoglycan (GO:0005203);sugar binding (GO:0005529) C-type lectin (IPR001304);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436);Type II EGF-like signature (IPR001438);Type II antifreeze protein (IPR002353) high 10.2829872026 216894_x_at CDKN1C BWCR;BWS;CDKN1C;KIP2;WBS;p57 1028 cyclin-dependent kinase inhibitor 1C (p57, Kip2) cell growth and/or maintenance (GO:0008151);cyclin-dependent protein kinase inhibitor activity (GO:0004861);negative regulation of cell proliferation (GO:0008285);nutrient reservoir activity (GO:0045735);oncogenesis (GO:0007048);regulation of cyclin dependent protein kinase activity (GO:0000079);tumor suppressor (GO:0008181) Bipartite nuclear localization signal (IPR001472);Cyclin-dependent kinase inhibitor (IPR003175);Glutelin (IPR000480);Proline-rich region (IPR000694) high 10.265237401 221731_x_at CSPG2 CSPG2;VERSICAN 1462 chondroitin sulfate proteoglycan 2 (versican) calcium ion binding (GO:0005509);cell adhesion (GO:0007155);chondroitin sulfate proteoglycan (GO:0005204);development (GO:0007275);glycosaminoglycan binding (GO:0005539);heterophilic cell adhesion (GO:0007157);hyaluronic acid binding (GO:0005540);lectin (GO:0005530);proteoglycan (GO:0005203);sugar binding (GO:0005529) C-type lectin (IPR001304);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436);Type II EGF-like signature (IPR001438);Type II antifreeze protein (IPR002353) high 10.258339241 204039_at CEBPA C/EBP-alpha;CEBP;CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha DNA binding (GO:0003677);RNA polymerase II transcription factor activity, enhancer binding (GO:0003705);energy pathways (GO:0006091);transcription (GO:0006350);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) None high 10.2518828633 204824_at ENDOG ENDOG 2021 endonuclease G DNA binding (GO:0003677);DNA metabolism (GO:0006259);endonuclease activity (GO:0004519);hydrolase activity (GO:0016787);magnesium ion binding (GO:0000287) DNA/RNA non-specific endonuclease (IPR001604) high 10.2107212054 210395_x_at MYL4 ALC1;AMLC;GT1;MYL4;PRO1957 4635 myosin, light polypeptide 4, alkali; atrial, embryonic calcium ion binding (GO:0005509);muscle development (GO:0007517);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048);Proline-rich region (IPR000694) high 10.1912481824 201903_at UQCRC1 D3S3191;UQCRC1 7384 ubiquinol-cytochrome c reductase core protein I aerobic respiration (GO:0009060);electron transport (GO:0006118);metalloendopeptidase activity (GO:0004222);oxidative phosphorylation (GO:0006119);oxidoreductase activity (GO:0016491);proteolysis and peptidolysis (GO:0006508);ubiquinol-cytochrome-c reductase activity (GO:0008121) Bipartite nuclear localization signal (IPR001472);Insulinase-like (IPR001431);Peptidase M16, C-terminal (IPR007863) high 10.1799899193 218208_at PQLC1 FLJ22378;PQLC1 80148 PQ loop repeat containing 1 None None high 10.1788892221 220807_at HBQ1 HBQ1 3049 hemoglobin, theta 1 globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Pi haemoglobin (IPR002339) high 10.1775312298 208352_x_at ANK1 ANK;ANK1;SPH1;SPH2 286 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 10.1409124748 31874_at GAS2L1 GAR22;GAS2L1;MGC17243 10634 growth arrest-specific 2 like 1 cell growth and/or maintenance (GO:0008151) Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);Growth-arrest-specific protein 2 (IPR003108);Proline-rich region (IPR000694) high 10.1298083762 201403_s_at MGST3 GST-III;MGST3 4259 microsomal glutathione S-transferase 3 antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);glutathione transferase activity (GO:0004364);lipid metabolism (GO:0006629);peroxidase activity (GO:0004601);signal transduction (GO:0007165);transferase activity (GO:0016740) Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) (IPR001129);TonB-dependent receptor (IPR000531) high 10.0838916203 210146_x_at LILRB2 CD85C;CD85D;ILT4;LILRB2;LILRB5;LIR-2;LIR-8;LIR2;LIR8;MIR-10;MIR10 10288 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 antimicrobial humoral response (sensu Protostomia) (GO:0006960);cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);cellular defense response (GO:0006968);defense response (GO:0006952);defense/immunity protein activity (GO:0003793);immune response (GO:0006955);receptor activity (GO:0004872);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 10.0674344693 202888_s_at ANPEP ANPEP;CD13;LAP1;PEPN;gp150 290 alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) aminopeptidase activity (GO:0004177);hydrolase activity (GO:0016787);membrane alanyl aminopeptidase activity (GO:0004179);metallopeptidase activity (GO:0008237);pathogenesis (GO:0009405);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);zinc ion binding (GO:0008270) Peptidase M1, membrane alanine aminopeptidase (IPR001930) high 10.016555853 214696_at MGC14376 MGC14376 84981 hypothetical protein MGC14376 None None high 9.94228194808 222078_at PKLR PK1;PKL;PKLR;RPK 5313 pyruvate kinase, liver and RBC glycolysis (GO:0006096);magnesium ion binding (GO:0000287);pyruvate kinase activity (GO:0004743);transferase activity (GO:0016740) Beta-ketoacyl synthase (IPR000794);Pyruvate kinase (IPR001697) high 9.93960348997 210929_s_at AHSG AHS;AHSG;FETUA;HSGA 197 alpha-2-HS-glycoprotein acute-phase response (GO:0006953);collagen (GO:0005202);cysteine protease inhibitor activity (GO:0004869);kinase inhibitor activity (GO:0019210);pinocytosis (GO:0006907);plasma glycoprotein (GO:0005211);proteoglycan (GO:0005203);skeletal development (GO:0001501) Cysteine protease inhibitor (IPR000010);Fetuin (IPR001363);Proline-rich region (IPR000694) high 9.91705885219 218676_s_at PCTP PCTP;STARD2 58488 phosphatidylcholine transfer protein lipid binding (GO:0008289);lipid transport (GO:0006869);phosphatidylcholine transporter activity (GO:0008525) Lipid-binding START (IPR002913) high 9.90286186816 202449_s_at RXRA NR2B1;RXRA 6256 retinoid X receptor, alpha DNA binding (GO:0003677);receptor activity (GO:0004872);retinoic acid receptor activity (GO:0003708);retinoid-X receptor activity (GO:0004886);signal transduction (GO:0007165);steroid binding (GO:0005496);steroid hormone receptor activity (GO:0003707);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);vitamin metabolism (GO:0006766) Ligand-binding domain of nuclear hormone receptor (IPR000536);Retinoic acid receptor (IPR003078);Retinoid X receptor (IPR000003);Steroid hormone receptor (IPR001723);Steroid nuclear receptor, ligand-binding (IPR008946);Transcription factor COUP (IPR003068);Vitamin D receptor (IPR000324);Zn-finger, C4-type steroid receptor (IPR001628) high 9.88613002498 200799_at HSPA1A HSP70-1;HSP72;HSPA1;HSPA1A 3303 heat shock 70kDa protein 1A heat shock protein activity (GO:0003773);mRNA catabolism (GO:0006402) Bipartite nuclear localization signal (IPR001472);Heat shock protein Hsp70 (IPR001023) high 9.81665622239 207857_at LILRB1 CD85;CD85H;CD85I;CD85J;ILT1;ILT2;LILRA1;LILRA2;LILRB1;LIR-1;LIR-6;LIR-7;LIR1;LIR6;LIR7;MIR-7;MIR7 10859 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 MHC-interacting protein (GO:0003822);antigen binding (GO:0003823);cell surface receptor linked signal transduction (GO:0007166);defense response (GO:0006952);immune response (GO:0006955);protein phosphatase 1 binding (GO:0008157);receptor activity (GO:0004872);response to virus (GO:0009615);signal transduction (GO:0007165);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 9.80878380503 212041_at ATP6V0D1 ATP6D;ATP6DV;ATP6V0D1;P39;VATX;VPATPD;Vma6 9114 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1 ATP biosynthesis (GO:0006754);hydrogen ion transporter activity (GO:0015078);hydrogen-transporting two-sector ATPase activity (GO:0003936);hydrolase activity (GO:0016787);molecular_function unknown (GO:0005554);proton transport (GO:0015992) H+-transporting two-sector ATPase, C (AC39) subunit (IPR002843) high 9.79461716876 211571_s_at CSPG2 CSPG2;VERSICAN 1462 chondroitin sulfate proteoglycan 2 (versican) calcium ion binding (GO:0005509);cell adhesion (GO:0007155);chondroitin sulfate proteoglycan (GO:0005204);development (GO:0007275);glycosaminoglycan binding (GO:0005539);heterophilic cell adhesion (GO:0007157);hyaluronic acid binding (GO:0005540);lectin (GO:0005530);proteoglycan (GO:0005203);sugar binding (GO:0005529) C-type lectin (IPR001304);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436);Type II EGF-like signature (IPR001438);Type II antifreeze protein (IPR002353) high 9.78898725473 217763_s_at RAB31 RAB31;Rab22B 11031 RAB31, member RAS oncogene family GTP binding (GO:0005525);RAB small monomeric GTPase activity (GO:0003928);protein transport (GO:0015031);small GTPase mediated signal transduction (GO:0007264) GTP-binding nuclear protein Ran (IPR002041);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) high 9.74681868615 213395_at MLC1 KIAA0027;LVM;MLC;MLC1 23209 megalencephalic leukoencephalopathy with subcortical cysts 1 biological_process unknown (GO:0000004);ion channel activity (GO:0005216);molecular_function unknown (GO:0005554);transport (GO:0006810) Ribosomal protein S14 (IPR001209) high 9.73982931007 204168_at MGST2 GST2;MGC14097;MGST-II;MGST2 4258 microsomal glutathione S-transferase 2 antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell-cell signaling (GO:0007267);enzyme activator activity (GO:0008047);glutathione transferase activity (GO:0004364);leukotriene biosynthesis (GO:0019370);leukotriene metabolism (GO:0006691);signal transduction (GO:0007165);transferase activity (GO:0016740) 5-lipoxygenase-activating protein (IPR001446);Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) (IPR001129) high 9.73412308047 213524_s_at G0S2 G0S2 50486 putative lymphocyte G0/G1 switch gene cell growth and/or maintenance (GO:0008151);molecular_function unknown (GO:0005554) None high 9.73073271707 217572_at AA654586.1 None None None None None high 9.70996859926 218695_at EXOSC4 EXOSC4;FLJ20591;RRP41;RRP41A;Rrp41p;SKI6;Ski6p;hRrp41p;p12A 54512 exosome component 4 3'-5'-exoribonuclease activity (GO:0000175);RNA binding (GO:0003723);exonuclease activity (GO:0004527);hydrolase activity (GO:0016787);rRNA processing (GO:0006364) 3' exoribonuclease (IPR001247) high 9.70947549407 221748_s_at TNS DKFZP434G162;FLJ10923;PRO0929;TNS;TNS1 7145 tensin intracellular signaling cascade (GO:0007242) C2 calcium/lipid-binding domain, CaLB (IPR008973);Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209);Phosphotyrosine interaction domain (IPR006020);Protein tyrosine phosphatase, catalytic region (IPR003595);SH2 motif (IPR000980) high 9.70370630855 218559_s_at MAFB KRML;MAFB;MGC43127 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) DNA binding (GO:0003677) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Eukaryotic transcription factor, DNA-binding (IPR008917);Maf transcription factor (IPR004826) high 9.69745541406 208470_s_at HPR HPR 3250 haptoglobin-related protein chymotrypsin activity (GO:0004263);hemoglobin binding (GO:0030492);peptidase activity (GO:0008233);plasma protein (GO:0005209);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Haptoglobin (IPR008292);Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003);Sushi domain/SCR domain/CCP module (IPR000436) high 9.69020874527 208970_s_at UROD PCT;UROD 7389 uroporphyrinogen decarboxylase heme biosynthesis (GO:0006783);lyase activity (GO:0016829);uroporphyrinogen decarboxylase activity (GO:0004853) Uroporphyrinogen decarboxylase (URO-D) (IPR000257);Uroporphyrinogen decarboxylase HemE (IPR006361) high 9.68400715099 210504_at KLF1 EKLF;KLF1 10661 Kruppel-like factor 1 (erythroid) histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) high 9.68356534924 202890_at MAP7 E-MAP-115;EMAP115;MAP7 9053 microtubule-associated protein 7 establishment and/or maintenance of cell polarity (GO:0007163);microtubule cytoskeleton organization and biogenesis (GO:0000226);structural molecule activity (GO:0005198) Bipartite nuclear localization signal (IPR001472);E-MAP-115 (IPR008604);Proline-rich region (IPR000694) high 9.66985365837 gnf1h08166_at gnf1h08166_at None None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) high 9.65363104781 204467_s_at SNCA NACP;PARK1;PD1;SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) pathogenesis (GO:0009405);structural molecule activity (GO:0005198) Alpha-synuclein (IPR002460);Gamma-synuclein (IPR002462);Synuclein (IPR001058) high 9.61682010292 203948_s_at MPO MPO 4353 myeloperoxidase calcium ion binding (GO:0005509);chromatin binding (GO:0003682);defense response (GO:0006952);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);response to oxidative stress (GO:0006979) Animal haem peroxidase (IPR002007);Haem peroxidase, plant/fungal/bacterial (IPR002016) high 9.60691221721 205449_at HSU79266 HSU79266 29901 protein predicted by clone 23627 DNA binding (GO:0003677) Proline-rich region (IPR000694);SAC3/GANP family (IPR005062) high 9.60383692726 202426_s_at RXRA NR2B1;RXRA 6256 retinoid X receptor, alpha DNA binding (GO:0003677);receptor activity (GO:0004872);retinoic acid receptor activity (GO:0003708);retinoid-X receptor activity (GO:0004886);signal transduction (GO:0007165);steroid binding (GO:0005496);steroid hormone receptor activity (GO:0003707);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);vitamin metabolism (GO:0006766) Ligand-binding domain of nuclear hormone receptor (IPR000536);Retinoic acid receptor (IPR003078);Retinoid X receptor (IPR000003);Steroid hormone receptor (IPR001723);Steroid nuclear receptor, ligand-binding (IPR008946);Transcription factor COUP (IPR003068);Vitamin D receptor (IPR000324);Zn-finger, C4-type steroid receptor (IPR001628) high 9.60296082442 209962_at EPOR EPOR 2057 erythropoietin receptor erythropoietin receptor activity (GO:0004900);guanyl-nucleotide exchange factor activity (GO:0005085);intracellular signaling cascade (GO:0007242);neuropeptide signaling pathway (GO:0007218);signal transduction (GO:0007165);small GTPase mediated signal transduction (GO:0007264) Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Guanine-nucleotide dissociation stimulator CDC25 (IPR001895);Long hematopoietin receptor, single chain (IPR003528);Oxidoreductase, molybdopterin binding (IPR000572);RA domain (IPR000159);Ras guanine nucleotide exchange factor (IPR008937) high 9.57021634041 204766_s_at NUDT1 MTH1;NUDT1 4521 nudix (nucleoside diphosphate linked moiety X)-type motif 1 8-oxo-7,8-dihydroguanine triphosphatase activity (GO:0008413);DNA repair (GO:0006281);GTPase activity (GO:0003924);hydrolase activity (GO:0016787);response to oxidative stress (GO:0006979) 7,8-dihydro-8-oxoguanine triphosphatase (IPR003563);NUDIX hydrolase (IPR000086) high 9.55907956101 217728_at S100A6 2A9;5B10;CABP;CACY;PRA;S100A6 6277 S100 calcium binding protein A6 (calcyclin) calcium ion binding (GO:0005509);cell-cell signaling (GO:0007267);growth factor activity (GO:0008083);protein binding (GO:0005515) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 9.52916022803 202974_at MPP1 DXS552;DXS552E;EMP55;MPP1;PEMP 4354 membrane protein, palmitoylated 1, 55kDa guanylate kinase activity (GO:0004385);intracellular signaling cascade (GO:0007242);protein binding (GO:0005515);signal transduction (GO:0007165) Guanylate kinase (IPR008144);Guanylate kinase/L-type calcium channel region (IPR008145);PDZ/DHR/GLGF domain (IPR001478);SH3 (IPR001452) high 9.52239685605 201218_at CTBP2 CTBP2;MGC70870 1488 C-terminal binding protein 2 L-serine biosynthesis (GO:0006564);negative regulation of cell proliferation (GO:0008285);oxidoreductase activity (GO:0016491);oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);tumor suppressor (GO:0008181);viral replication (GO:0008166) D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (IPR006140);D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139) high 9.51383854091 208949_s_at LGALS3 CBP35;GAL3;GALBP;GALIG;LGALS2;LGALS3;MAC2 3958 lectin, galactoside-binding, soluble, 3 (galectin 3) IgE binding (GO:0019863);galactose binding (GO:0005534);galactose binding lectin (GO:0005531);heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);sugar binding (GO:0005529) Concanavalin A-like lectin/glucanase (IPR008985);Galectin, galactose-binding lectin (IPR001079);Proline-rich region (IPR000694) high 9.51365893893 210660_at LILRB1 CD85;CD85H;CD85I;CD85J;ILT1;ILT2;LILRA1;LILRA2;LILRB1;LIR-1;LIR-6;LIR-7;LIR1;LIR6;LIR7;MIR-7;MIR7 10859 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 MHC-interacting protein (GO:0003822);antigen binding (GO:0003823);cell surface receptor linked signal transduction (GO:0007166);defense response (GO:0006952);immune response (GO:0006955);protein phosphatase 1 binding (GO:0008157);receptor activity (GO:0004872);response to virus (GO:0009615);signal transduction (GO:0007165);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 9.49952420848 204416_x_at APOC1 APOC1 341 apolipoprotein C-I lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157) Apolipoprotein C-I (IPR006781) high 9.49305242101 220973_s_at DKFZP434N1923 DKFZP434N1923 81858 hypothetical protein DKFZp434N1923 kinase activity (GO:0016301) Zn-finger, Ran-binding (IPR001876) high 9.4811535611 gnf1h08679_at C20orf108 5A3;C20orf108;DKFZP434A1114;dJ1167H4.1 116151 chromosome 20 open reading frame 108 None None high 9.46753947041 212423_at C10orf56 C10orf56;FLJ90798 219654 chromosome 10 open reading frame 56 nucleic acid binding (GO:0003676) Bipartite nuclear localization signal (IPR001472);Zn-finger, CCHC type (IPR001878) high 9.46710869664 207087_x_at ANK1 ANK;ANK1;SPH1;SPH2 286 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 9.45113369835 209185_s_at IRS2 IRS2 8660 insulin receptor substrate 2 glucose metabolism (GO:0006006);insulin receptor binding (GO:0005158);positive regulation of cell proliferation (GO:0008284);receptor activity (GO:0004872);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Insulin receptor substrate-1, PTB (IPR002404);Pleckstrin-like (IPR001849);Proline-rich region (IPR000694) high 9.4418304023 207194_s_at ICAM4 ICAM4 3386 intercellular adhesion molecule 4, Landsteiner-Wiener blood group cell adhesion molecule activity (GO:0005194);cell-cell adhesion (GO:0016337);integrin binding (GO:0005178);protein binding (GO:0005515) Immunoglobulin-like (IPR007110);Intercellular adhesion molecule/vascular cell adhesion molecule-1 (IPR003987) high 9.3963004436 205837_s_at GYPA GPA;GYPA;MNS 2993 glycophorin A (includes MN blood group) biological_process unknown (GO:0000004);blood group antigen (GO:0005555);invasive growth (GO:0007125);molecular_function unknown (GO:0005554) Glycophorin A and B (IPR001195) high 9.39457103685 210554_s_at CTBP2 CTBP2;MGC70870 1488 C-terminal binding protein 2 L-serine biosynthesis (GO:0006564);negative regulation of cell proliferation (GO:0008285);oxidoreductase activity (GO:0016491);oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);tumor suppressor (GO:0008181);viral replication (GO:0008166) D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain (IPR006140);D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (IPR006139) high 9.38953675116 205020_s_at ARL4A ARL4;ARL4A 10124 ADP-ribosylation factor-like 4A GTP binding (GO:0005525);GTPase activity (GO:0003924);small GTPase mediated signal transduction (GO:0007264);small monomeric GTPase activity (GO:0003925) ADP-ribosylation factor (IPR006688);ARF/SAR superfamily (IPR006689);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Small GTP-binding protein domain (IPR005225) high 9.38623000566 205390_s_at ANK1 ANK;ANK1;SPH1;SPH2 286 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 9.38009625892 201506_at TGFBI BIGH3;CDB1;CDG2;CDGG1;CSD;CSD1;CSD2;CSD3;LCD1;TGFBI 7045 transforming growth factor, beta-induced, 68kDa cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell proliferation (GO:0008283);integrin binding (GO:0005178);negative regulation of cell adhesion (GO:0007162);protein binding (GO:0005515);structural molecule activity (GO:0005198);tumor suppressor (GO:0008181);visual perception (GO:0007601) Beta-Ig-H3/fasciclin (IPR000782) high 9.36844319667 205715_at BST1 BST1;CD157 683 bone marrow stromal cell antigen 1 GPI-anchored membrane-bound receptor (GO:0015025);NAD+ nucleosidase activity (GO:0003953);development (GO:0007275);humoral immune response (GO:0006959);hydrolase activity (GO:0016787) ADP-ribosyl cyclase (CD38/157) (IPR003193) high 9.36839422222 209729_at GAS2L1 GAR22;GAS2L1;MGC17243 10634 growth arrest-specific 2 like 1 cell growth and/or maintenance (GO:0008151) Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);Growth-arrest-specific protein 2 (IPR003108);Proline-rich region (IPR000694) high 9.35541953957 203669_s_at DGAT1 ARGP1;DGAT;DGAT1 8694 diacylglycerol O-acyltransferase homolog 1 (mouse) acyltransferase activity (GO:0008415);diacylglycerol O-acyltransferase activity (GO:0004144);fat body development (GO:0007503);transferase activity (GO:0016740);triacylglycerol metabolism (GO:0006641) Membrane bound O-acyl transferase, MBOAT (IPR004299) high 9.35276223028 214063_s_at TF PRO1557;PRO2086 7018 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 9.34948339664 208886_at H1F0 H10;H1F0;H1FV;MGC5241 3005 H1 histone family, member 0 DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H1/H5 (IPR005818);Histone H5 (IPR005819);Linker histone, N-terminal (IPR003216);Winged helix DNA-binding (IPR009058) high 9.33773190342 220005_at GPR86 FKSG77;GPCR1;GPR86;GPR94;P2Y13;SP174 53829 G protein-coupled receptor 86 G-protein coupled receptor activity, unknown ligand (GO:0016526);G-protein coupled receptor protein signaling pathway (GO:0007186);biological_process unknown (GO:0000004);purinergic nucleotide receptor activity\, G-protein coupled (GO:0045028);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584) Bipartite nuclear localization signal (IPR001472);P2Y13 purinoceptor (IPR008109);Rhodopsin-like GPCR superfamily (IPR000276) high 9.33438439146 211546_x_at SNCA NACP;PARK1;PD1;SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) pathogenesis (GO:0009405);structural molecule activity (GO:0005198) Alpha-synuclein (IPR002460);Gamma-synuclein (IPR002462);Synuclein (IPR001058) high 9.32816388871 214464_at CDC42BPA CDC42BPA;FLJ23347;KIAA0451;MRCK;MRCKA;PK428 8476 CDC42 binding protein kinase alpha (DMPK-like) ATP binding (GO:0005524);intracellular signaling cascade (GO:0007242);kinase activity (GO:0016301);protein amino acid phosphorylation (GO:0006468);protein serine/threonine kinase activity (GO:0004674);small GTPase regulatory/interacting protein activity (GO:0005083) Bipartite nuclear localization signal (IPR001472);C-type lectin (IPR001304);Citron-like (IPR001180);PAK-box/P21-Rho-binding (IPR000095);Pleckstrin-like (IPR001849);Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 9.32205805931 201714_at TUBG1 TUBG;TUBG1 7283 tubulin, gamma 1 GTP binding (GO:0005525);GTPase activity (GO:0003924);meiotic spindle assembly (GO:0000212);microtubule cytoskeleton organization and biogenesis (GO:0000226);microtubule nucleation (GO:0007020);microtubule polymerization (GO:0046785);microtubule-based movement (GO:0007018);mitotic spindle assembly (GO:0007052);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Gamma tubulin (IPR002454);Tubulin (IPR000217);Tubulin/FtsZ, C-terminal (IPR008280);Tubulin/FtsZ, GTPase (IPR003008) high 9.31598315201 203382_s_at APOE APOE 348 apolipoprotein E antioxidant activity (GO:0016209);apolipoprotein E receptor binding (GO:0050749);beta-amyloid binding (GO:0001540);cholesterol homeostasis (GO:0042632);cholesterol metabolism (GO:0008203);circulation (GO:0008015);cytoskeleton organization and biogenesis (GO:0007010);development (GO:0007275);heparin binding (GO:0008201);immune response (GO:0006955);intracellular transport (GO:0046907);learning and/or memory (GO:0007611);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);low-density lipoprotein receptor binding (GO:0050750);plasma protein (GO:0005209);receptor binding (GO:0005102);response to reactive oxygen species (GO:0000302);tau protein binding (GO:0048156) Apolipoprotein A1/A4/E (IPR000074) high 9.31593529033 210451_at PKLR PK1;PKL;PKLR;RPK 5313 pyruvate kinase, liver and RBC glycolysis (GO:0006096);magnesium ion binding (GO:0000287);pyruvate kinase activity (GO:0004743);transferase activity (GO:0016740) Beta-ketoacyl synthase (IPR000794);Pyruvate kinase (IPR001697) high 9.31590687704 217889_s_at CYBRD1 CYBRD1;DCYTB;FLJ23462 79901 cytochrome b reductase 1 electron transport (GO:0006118) Cytochrome b561 (IPR004877);Cytochrome b561 / ferric reductase transmembrane (IPR006593);Peptidase S26, signal peptidase I (IPR000508) high 9.28850943704 201162_at IGFBP7 FSTL2;IGFBP-7;IGFBP7;MAC25;PSF 3490 insulin-like growth factor binding protein 7 insulin-like growth factor binding (GO:0005520);negative regulation of cell proliferation (GO:0008285);regulation of cell growth (GO:0001558) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Insulin-like growth factor-binding protein, IGFBP (IPR000867);Proteinase inhibitor I1, Kazal (IPR002350) high 9.28497605471 206568_at TNP1 TNP1;TP1 7141 transition protein 1 (during histone to protamine replacement) DNA binding (GO:0003677);chromatin silencing (GO:0006342);chromosome condensation (GO:0000068);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome disassembly (GO:0006337);sexual reproduction (GO:0019953);single strand break repair (GO:0000012);sperm motility (GO:0030317);spermatogenesis (GO:0007283) Nuclear transition protein 1 (IPR001319) high 9.28481748975 39729_at PRDX2 MGC4104;NKEFB;PRDX2;PRP;PRXII;TDPX1;TSA 7001 peroxiredoxin 2 antioxidant activity (GO:0016209);electron transporter activity (GO:0005489);killer activity (GO:0007583);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);peroxidase reaction (GO:0006804);response to oxidative stress (GO:0006979);thioredoxin peroxidase activity (GO:0008379) Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) high 9.27025284949 213946_s_at KIAA0657 KIAA0657 23363 KIAA0657 protein None Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Immunoglobulin C-2 type (IPR003598);Immunoglobulin-like (IPR007110);TONB Box N terminus (IPR010916) high 9.26326159996 201044_x_at DUSP1 CL100;DUSP1;HVH1;MKP-1;PTPN10 1843 dual specificity phosphatase 1 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);non-membrane spanning protein tyrosine phosphatase activity (GO:0004726);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein tyrosine/serine/threonine phosphatase activity (GO:0008138);response to oxidative stress (GO:0006979) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Protein tyrosine phosphatase, catalytic region (IPR003595);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 9.25932105626 205012_s_at HAGH GLO2;GLXII;HAGH;HAGH1 3029 hydroxyacylglutathione hydrolase hydrolase activity (GO:0016787);hydroxyacylglutathione hydrolase activity (GO:0004416) Beta-lactamase-like (IPR001279) high 9.2555492406 211074_at 211074_at None None Homo sapiens non-functional folate binding protein mRNA, complete cds. None None high 9.23608048325 220615_s_at MLSTD1 FLJ10462;MLSTD1 55711 male sterility domain containing 1 None Male sterility protein (IPR004262) high 9.23544420733 204620_s_at CSPG2 CSPG2;VERSICAN 1462 chondroitin sulfate proteoglycan 2 (versican) calcium ion binding (GO:0005509);cell adhesion (GO:0007155);chondroitin sulfate proteoglycan (GO:0005204);development (GO:0007275);glycosaminoglycan binding (GO:0005539);heterophilic cell adhesion (GO:0007157);hyaluronic acid binding (GO:0005540);lectin (GO:0005530);proteoglycan (GO:0005203);sugar binding (GO:0005529) C-type lectin (IPR001304);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436);Type II EGF-like signature (IPR001438);Type II antifreeze protein (IPR002353) high 9.22328707256 203400_s_at TF PRO1557;PRO2086 7018 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 9.20763798183 218436_at SIL1 BAP;SIL1 64374 endoplasmic reticulum chaperone SIL1, homolog of yeast chaperone activity (GO:0003754);intracellular protein transport (GO:0006886);protein folding (GO:0006457) ARM repeat fold (IPR008938) high 9.19481598853 208892_s_at DUSP6 DUSP6;MKP3;PYST1 1848 dual specificity phosphatase 6 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);MAPKKK cascade (GO:0000165);apoptosis (GO:0006915);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);phosphoprotein phosphatase activity (GO:0004721);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein serine/threonine phosphatase activity (GO:0004722);protein tyrosine phosphatase activity (GO:0004725);protein tyrosine/serine/threonine phosphatase activity (GO:0008138) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 9.19420588843 200765_x_at CTNNA1 CAP102;CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);structural molecule activity (GO:0005198) Alpha-catenin (IPR001033);Vinculin (IPR000633);Vinculin/alpha-catenin (IPR006077) high 9.17164395714 216925_s_at TAL1 SCL;TAL1;TCL5 6886 T-cell acute lymphocytic leukemia 1 DNA binding (GO:0003677);cell differentiation (GO:0030154);cell proliferation (GO:0008283);oncogenesis (GO:0007048) Basic helix-loop-helix dimerization domain bHLH (IPR001092) high 9.15971419129 200838_at CTSB APPS;CPSB;CTSB 1508 cathepsin B cathepsin B activity (GO:0004213);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508) Peptidase C1A, papain (IPR000668);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 9.15776815616 210933_s_at FSCN1 FSCN1;SNL;p55 6624 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) actin bundling activity (GO:0003781);actin cytoskeleton organization and biogenesis (GO:0030036);actin cytoskeleton reorganization (GO:0007012);cell proliferation (GO:0008283) Actin-crosslinking proteins (IPR008999);Fascin (IPR010431) high 9.15396377137 201163_s_at IGFBP7 FSTL2;IGFBP-7;IGFBP7;MAC25;PSF 3490 insulin-like growth factor binding protein 7 insulin-like growth factor binding (GO:0005520);negative regulation of cell proliferation (GO:0008285);regulation of cell growth (GO:0001558) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Insulin-like growth factor-binding protein, IGFBP (IPR000867);Proteinase inhibitor I1, Kazal (IPR002350) high 9.14967328169 218454_at FLJ22662 FLJ22662 79887 hypothetical protein FLJ22662 None Laminin A (IPR007000) high 9.12568996228 210430_x_at RHCE RH30A;RHC;RHCE;RHE;RHIXB;RHPI;Rh4;RhVI;RhVIII 6006 Rhesus blood group, CcEe antigens ammonium transporter activity (GO:0008519);blood group antigen (GO:0005555);transport (GO:0006810);transporter activity (GO:0005215) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 9.11039600226 218489_s_at ALAD ALAD;ALADH;MGC5057 210 aminolevulinate, delta-, dehydratase catalytic activity (GO:0003824);heme biosynthesis (GO:0006783);lyase activity (GO:0016829);porphobilinogen synthase activity (GO:0004655) Delta-aminolevulinic acid dehydratase (IPR001731) high 9.10279495658 gnf1h01561_s_at FLJ20449 FLJ20449 54937 hypothetical protein FLJ20449 None Basic helix-loop-helix dimerization domain bHLH (IPR001092);Bipartite nuclear localization signal (IPR001472) high 9.09403082789 216833_x_at GYPB GYPB;MNS 2994 glycophorin B (includes Ss blood group) blood group antigen (GO:0005555);receptor activity (GO:0004872);signal transduction (GO:0007165) Glycophorin A and B (IPR001195) high 9.08212071031 212224_at ALDH1A1 ALDC;ALDH-E1;ALDH1;ALDH11;ALDH1A1;MGC2318;PUMB1;RALDH1 216 aldehyde dehydrogenase 1 family, member A1 aldehyde dehydrogenase (NAD) activity (GO:0004029);aldehyde metabolism (GO:0006081);androgen binding (GO:0005497);electron transporter activity (GO:0005489);oxidoreductase activity (GO:0016491) Aldehyde dehydrogenase (IPR002086) high 9.08129429254 204981_at SLC22A18 BWR1A;BWSCR1A;HET;IMPT1;ITM;ORCTL2;SLC22A18;SLC22A1L;TSSC5;p45-BWR1A 5002 solute carrier family 22 (organic cation transporter), member 18 drug resistance (GO:0009315);excretion (GO:0007588);oncogenesis (GO:0007048);organic cation transporter activity (GO:0015101);response to drug (GO:0042493);small molecule transport (GO:0006832);tetracycline transport (GO:0015904);tetracycline:hydrogen antiporter activity (GO:0015520);transporter activity (GO:0005215) Major facilitator superfamily (IPR007114);Tetracycline resistance protein (IPR001958) high 9.06987439181 220734_s_at MGC10334 MGC10334 80772 hypothetical protein MGC10334 None Proline-rich region (IPR000694) high 9.06545704832 220024_s_at PRX CMT4F;KIAA1620;PRX 57716 periaxin intracellular signaling cascade (GO:0007242);mechanosensory behavior (GO:0007638);molecular_function unknown (GO:0005554);protein binding (GO:0005515) PDZ/DHR/GLGF domain (IPR001478);Proline-rich region (IPR000694) high 9.04624447514 205967_at HIST1H4F H4/c;H4/g;H4FC;H4FG;HIST1H4C;HIST1H4F;dJ221C16.1 8361 histone 1, H4f DNA binding (GO:0003677);DNA packaging (GO:0006323) Histone H4 (IPR001951);Histone core (IPR007125);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 9.04532780311 gnf1h05057_s_at PP3856 PP3856 93100 similar to CG3714 gene product None Bipartite nuclear localization signal (IPR001472);Nicotinate phosphoribosyltransferase and related (IPR007229);Nicotinate phosphoribosyltransferase related (IPR006405) high 9.02978678829 208977_x_at TUBB2 TUBB2 10383 tubulin, beta, 2 GTP binding (GO:0005525);MHC class I protein binding (GO:0042288);chaperone activity (GO:0003754);microtubule-based movement (GO:0007018);microtubule-based process (GO:0007017);natural killer cell mediated cytolysis (GO:0042267);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Alpha tubulin (IPR002452);Beta tubulin (IPR002453);Cell division protein FtsZ (IPR000158);Delta tubulin (IPR002967);Gamma tubulin (IPR002454);Tubulin (IPR000217);Tubulin/FtsZ, C-terminal (IPR008280);Tubulin/FtsZ, GTPase (IPR003008) high 9.02962077051 gnf1h02724_s_at LATS2 LATS2 26524 LATS, large tumor suppressor, homolog 2 (Drosophila) ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein serine/threonine kinase activity (GO:0004674);transferase activity (GO:0016740);tumor suppressor (GO:0008181) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);Protein kinase (IPR000719);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245);UBA-like (IPR009060);Ubiquitin-associated domain (IPR000449) high 9.02864985662 202833_s_at SERPINA1 A1A;A1AT;AAT;PI1;SERPINA1 5265 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 acute-phase response (GO:0006953);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibititor I4, serpin (IPR000215) high 9.01731121172 219905_at ERMAP ERMAP;PRO2801 114625 erythroblast membrane-associated protein None B302, (SPRY)-like (IPR001870);Immunoglobulin V-type (IPR003596);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);SPRY-associated domain (IPR006574);SPla/RYanodine receptor SPRY (IPR003877) high 9.00389028291 209581_at HRASLS3 H-REV107-1;HRASLS3;HREV107;HREV107-3 11145 HRAS-like suppressor 3 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) NC (IPR007053) high 8.99954520261 218486_at TIEG2 FKLF;FKLF1;KLF11;TIEG2 8462 TGFB inducible early growth response 2 negative regulation of cell proliferation (GO:0008285);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) high 8.97876394693 206146_s_at RHAG RH2;RH50A;RHAG 6005 Rhesus blood group-associated glycoprotein ammonium transport (GO:0015696);ammonium transporter activity (GO:0008519);ankyrin binding (GO:0030506);blood group antigen (GO:0005555);circulation (GO:0008015);protein complex assembly (GO:0006461);transport (GO:0006810) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 8.94829088497 213975_s_at LYZ LYZ 4069 lysozyme (renal amyloidosis) amyloid protein (GO:0005208);antimicrobial humoral response (sensu Protostomia) (GO:0006960);bacteriolytic toxin activity (GO:0015642);carbohydrate metabolism (GO:0005975);cell wall catabolism (GO:0016998);cytolysis (GO:0019835);hydrolase activity, acting on glycosyl bonds (GO:0016798);inflammatory response (GO:0006954);lysin activity (GO:0015465);lysozyme activity (GO:0003796);structural molecule activity (GO:0005198) Glycoside hydrolase, family 22 (IPR001916);Glycoside hydrolase, family 22, lysozyme (IPR000974) high 8.93730005121 201432_at CAT CAT 847 catalase catalase activity (GO:0004096);catalase reaction (GO:0006802);electron transport (GO:0006118);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);peroxidase reaction (GO:0006804);response to oxidative stress (GO:0006979) Catalase (IPR002226) high 8.92823681163 204187_at GMPR GMPR 2766 guanosine monophosphate reductase GMP reductase activity (GO:0003920);nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139);nucleotide metabolism (GO:0009117);oxidoreductase activity (GO:0016491);response to cold (GO:0009409) FMN/related compound-binding core (IPR003009);Guanosine monophosphate reductase 1 (IPR005993);IMP dehydrogenase/GMP reductase (IPR001093) high 8.92797715339 218847_at IMP-2 IMP-2;IMP2;VICKZ2 10644 IGF-II mRNA-binding protein 2 RNA binding (GO:0003723);embryogenesis and morphogenesis (GO:0007345);morphogenesis (GO:0009653) KH (IPR004087);KH, type 1 (IPR004088);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 8.91935104286 202096_s_at BZRP BZRP;MBR;PBR 706 benzodiazapine receptor (peripheral) benzodiazepine receptor activity (GO:0008503);mitochondrial translocation (GO:0006628);protein-mitochondrial targeting (GO:0006626);receptor activity (GO:0004872);signal transduction (GO:0007165) TspO/MBR-related protein (IPR004307) high 8.91637078789 216054_x_at MYL4 ALC1;AMLC;GT1;MYL4;PRO1957 4635 myosin, light polypeptide 4, alkali; atrial, embryonic calcium ion binding (GO:0005509);muscle development (GO:0007517);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048);Proline-rich region (IPR000694) high 8.90438915897 219952_s_at MCOLN1 MCOLN1;ML4;MLIV 57192 mucolipin 1 cation channel activity (GO:0005261);cation transport (GO:0006812) Bipartite nuclear localization signal (IPR001472);Cation (not K+) channel, TM region (IPR002111);Lipase (IPR000734);Retrovirus capsid, N-terminal core (IPR008919) high 8.90183551527 205311_at DDC AADC;DDC 1644 dopa decarboxylase (aromatic L-amino acid decarboxylase) amino acid metabolism (GO:0006520);aromatic-L-amino-acid decarboxylase activity (GO:0004058);catecholamine biosynthesis (GO:0042423);catecholamine metabolism (GO:0006584);lyase activity (GO:0016829) Pyridoxal-dependent decarboxylase (IPR002129) high 8.90167196446 214407_x_at GYPB GYPB;MNS 2994 glycophorin B (includes Ss blood group) blood group antigen (GO:0005555);receptor activity (GO:0004872);signal transduction (GO:0007165) Glycophorin A and B (IPR001195) high 8.86375553034 210088_x_at MYL4 ALC1;AMLC;GT1;MYL4;PRO1957 4635 myosin, light polypeptide 4, alkali; atrial, embryonic calcium ion binding (GO:0005509);muscle development (GO:0007517);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048);Proline-rich region (IPR000694) high 8.85380261824 204141_at TUBB TUBB 7280 tubulin, beta polypeptide GTP binding (GO:0005525);GTPase activity (GO:0003924);MHC class I protein binding (GO:0042288);chaperone activity (GO:0003754);microtubule polymerization (GO:0046785);microtubule-based movement (GO:0007018);natural killer cell mediated cytolysis (GO:0042267);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Alpha tubulin (IPR002452);Beta tubulin (IPR002453);Cell division protein FtsZ (IPR000158);Delta tubulin (IPR002967);Gamma tubulin (IPR002454);Tubulin (IPR000217);Tubulin/FtsZ, C-terminal (IPR008280);Tubulin/FtsZ, GTPase (IPR003008) high 8.85144888277 206709_x_at GPT AAT1;ALT1;GPT;GPT1 2875 glutamic-pyruvate transaminase (alanine aminotransferase) 1-aminocyclopropane-1-carboxylate synthase activity (GO:0016847);alanine transaminase activity (GO:0004021);amino acid metabolism (GO:0006520);biosynthesis (GO:0009058);gluconeogenesis (GO:0006094);nitrogen metabolism (GO:0006807);transaminase activity (GO:0008483);transferase activity (GO:0016740) 1-aminocyclopropane-1-carboxylate synthase (IPR001176);Aminotransferase, class I and II (IPR004839) high 8.85043403884 206937_at SPTA1 EL2;SPTA1 6708 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) actin cross-linking activity (GO:0003780);actin filament organization (GO:0007015);calcium ion binding (GO:0005509);structural constituent of cytoskeleton (GO:0005200) Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Neutrophil cytosol factor 2 (IPR000108);SH3 (IPR001452) high 8.82978974089 206358_at PRM1 PRM1 5619 protamine 1 DNA binding (GO:0003677);DNA packaging (GO:0006323);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);spermatogenesis (GO:0007283) Bipartite nuclear localization signal (IPR001472);Protamine P1 (IPR000221) high 8.81113355017 209631_s_at GPR37 EDNRBL;GPR37;PAELR 2861 G protein-coupled receptor 37 (endothelin receptor type B-like) G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor activity, unknown ligand (GO:0016526);G-protein coupled receptor protein signaling pathway (GO:0007186);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584) Bombesin receptor (IPR001556);GPR37 orphan receptor (IPR003909);Rhodopsin-like GPCR superfamily (IPR000276) high 8.81099434393 202456_s_at C9orf60 C9orf60;ZYG 10444 chromosome 9 open reading frame 60 None ARM repeat fold (IPR008938) high 8.80789068301 205418_at FES FES;FPS 2242 feline sarcoma oncogene ATP binding (GO:0005524);cell proliferation (GO:0008283);development (GO:0007275);intracellular signaling cascade (GO:0007242);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Bipartite nuclear localization signal (IPR001472);Cdc15/Fes/CIP4 (IPR001060);Protein kinase (IPR000719);SH2 motif (IPR000980);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 8.80192434038 209191_at MGC4083 MGC4083;TUBB-5 84617 tubulin beta MGC4083 G-protein coupled receptor protein signaling pathway (GO:0007186);GTP binding (GO:0005525);GTPase activity (GO:0003924);melanocyte stimulating hormone receptor activity (GO:0004980);microtubule polymerization (GO:0046785);microtubule-based movement (GO:0007018);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584);structural molecule activity (GO:0005198) Alpha tubulin (IPR002452);Beta tubulin (IPR002453);Bipartite nuclear localization signal (IPR001472);Cell division protein FtsZ (IPR000158);Delta tubulin (IPR002967);Gamma tubulin (IPR002454);Melanocortin receptor family (IPR001671);Melanocyte-stimulating hormone receptor (IPR000761);Rhodopsin-like GPCR superfamily (IPR000276);TonB-dependent receptor (IPR000531);Tubulin (IPR000217);Tubulin/FtsZ, C-terminal (IPR008280);Tubulin/FtsZ, GTPase (IPR003008) high 8.78694292123 205843_x_at CRAT CAT1;CRAT 1384 carnitine acetyltransferase acyl-CoA metabolism (GO:0006637);acyltransferase activity (GO:0008415);carnitine O-acetyltransferase activity (GO:0004092);energy derivation by oxidation of organic compounds (GO:0015980);energy pathways (GO:0006091);transferase activity (GO:0016740);transport (GO:0006810) Acyltransferase ChoActase/COT/CPT (IPR000542) high 8.78169513095 209297_at ITSN1 ITSN;ITSN1;SH3D1A;SH3P17 6453 intersectin 1 (SH3 domain protein) calcium ion binding (GO:0005509);endocytosis (GO:0006897);guanyl-nucleotide exchange factor activity (GO:0005085) Bipartite nuclear localization signal (IPR001472);C2 calcium/lipid-binding domain, CaLB (IPR008973);C2 domain (IPR000008);Calcium-binding EF-hand (IPR002048);DH domain (IPR000219);EPS15 homology (EH) (IPR000261);Neutrophil cytosol factor 2 (IPR000108);Pleckstrin-like (IPR001849);SH3 (IPR001452) high 8.76540957343 gnf1h09539_at MGC45871 MGC45871 359845 hypothetical protein MGC45871 None None high 8.7612991371 207664_at ADAM2 ADAM2;FTNB;PH-30b;PH30 2515 a disintegrin and metalloproteinase domain 2 (fertilin beta) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);fusion of sperm to egg plasma membrane (GO:0007342);integrin binding (GO:0005178);metalloendopeptidase activity (GO:0004222);metallopeptidase activity (GO:0008237);protein binding (GO:0005515);proteolysis and peptidolysis (GO:0006508) ADAM, cysteine-rich (IPR006586);Disintegrin (IPR001762);EGF-like domain (IPR006209);Peptidase M12B, ADAM/reprolysin (IPR001590);Peptidase M12B, propeptide (IPR002870) high 8.76123639167 207761_s_at DKFZP586A0522 DKFZP586A0522 25840 DKFZP586A0522 protein S-adenosylmethionine-dependent methyltransferase activity (GO:0008757) Generic methyltransferase (IPR001601);SAM (and some other nucleotide) binding motif (IPR000051) high 8.7612193524 203771_s_at BLVRA BLVR;BLVRA;BVRA 644 biliverdin reductase A biliverdin reductase activity (GO:0004074);electron transport (GO:0006118);electron transporter activity (GO:0005489);oxidoreductase activity (GO:0016491) Oxidoreductase, N-terminal (IPR000683) high 8.76109159045 219534_x_at CDKN1C BWCR;BWS;CDKN1C;KIP2;WBS;p57 1028 cyclin-dependent kinase inhibitor 1C (p57, Kip2) cell growth and/or maintenance (GO:0008151);cyclin-dependent protein kinase inhibitor activity (GO:0004861);negative regulation of cell proliferation (GO:0008285);nutrient reservoir activity (GO:0045735);oncogenesis (GO:0007048);regulation of cyclin dependent protein kinase activity (GO:0000079);tumor suppressor (GO:0008181) Bipartite nuclear localization signal (IPR001472);Cyclin-dependent kinase inhibitor (IPR003175);Glutelin (IPR000480);Proline-rich region (IPR000694) high 8.74766790151 215819_s_at RHCE RH30A;RHC;RHCE;RHE;RHIXB;RHPI;Rh4;RhVI;RhVIII 6006 Rhesus blood group, CcEe antigens ammonium transporter activity (GO:0008519);blood group antigen (GO:0005555);transport (GO:0006810);transporter activity (GO:0005215) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 8.74654049363 214146_s_at PPBP B-TG1;Beta-TG;CTAP3;CTAPIII;CXCL7;LA-PF4;LDGF;MDGF;NAP-2;NAP-2-L1;PBP;PPBP;SCYB7;TC1;TC2;TGB;TGB1;THBGB;THBGB1 5473 pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) cell proliferation (GO:0008283);chemokine activity (GO:0008009);chemotaxis (GO:0006935);extracellular matrix structural constituent (GO:0005201);glucose transport (GO:0015758);glucose transporter activity (GO:0005355);growth factor activity (GO:0008083);immune response (GO:0006955);plasma protein (GO:0005209);xenobiotic metabolism (GO:0006805) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 8.74292125956 218723_s_at RGC32 RGC32 28984 response gene to complement 32 cell cycle regulator (GO:0003750);regulation of cyclin dependent protein kinase activity (GO:0000079) None high 8.71760928388 215215_s_at LOC81691 DKFZp434J0315;LOC81691 81691 exonuclease NEF-sp exonuclease activity (GO:0004527);nucleic acid binding (GO:0003676) Exonuclease (IPR006055);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 8.71481359384 205936_s_at HK3 HK3;HKIII;HXK3 3101 hexokinase 3 (white cell) ATP binding (GO:0005524);glycolysis (GO:0006096);hexokinase activity (GO:0004396);kinase activity (GO:0016301);transferase activity (GO:0016740) Hexokinase (IPR001312) high 8.71245782268 207697_x_at LILRB2 CD85C;CD85D;ILT4;LILRB2;LILRB5;LIR-2;LIR-8;LIR2;LIR8;MIR-10;MIR10 10288 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 antimicrobial humoral response (sensu Protostomia) (GO:0006960);cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);cellular defense response (GO:0006968);defense response (GO:0006952);defense/immunity protein activity (GO:0003793);immune response (GO:0006955);receptor activity (GO:0004872);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 8.69084200981 212681_at EPB41L3 4.1B;DAL-1;DAL1;EPB41L3;KIAA0987 23136 erythrocyte membrane protein band 4.1-like 3 actin binding (GO:0003779);biological_process unknown (GO:0000004);cortical actin cytoskeleton organization and biogenesis (GO:0030866);molecular_function unknown (GO:0005554);structural molecule activity (GO:0005198) 4.1, C-terminal (IPR008379);Band 4.1 (IPR000299);Bipartite nuclear localization signal (IPR001472);Ezrin/radixin/moesin ERM (IPR000798);FERM (IPR009065);SAB (IPR007477) high 8.68926724638 206647_at HBZ HBZ 3050 hemoglobin, zeta globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Alpha haemoglobin (IPR002338);Bipartite nuclear localization signal (IPR001472);Globin (IPR000971);Myoglobin (IPR002335);Pi haemoglobin (IPR002339);Zeta haemoglobin (IPR002340) high 8.6886304362 gnf1h03297_x_at PQLC1 FLJ22378;PQLC1 80148 PQ loop repeat containing 1 None None high 8.68719416035 209189_at FOS FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog DNA binding (GO:0003677);DNA methylation (GO:0006306);cell growth and/or maintenance (GO:0008151);inflammatory response (GO:0006954);oncogenesis (GO:0007048);specific RNA polymerase II transcription factor activity (GO:0003704);transcription from Pol II promoter (GO:0006366) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Fos transforming protein (IPR000837) high 8.67303142793 203973_s_at KIAA0146 C/EBP-delta;CEBPD;CELF;CRP3;KIAA0146;NF-IL6-beta 23514 KIAA0146 protein DNA binding (GO:0003677);nucleic acid binding (GO:0003676);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) Bipartite nuclear localization signal (IPR001472);Nucleic acid-binding OB-fold (IPR008994) high 8.66955899521 210652_s_at C1orf34 C1orf34;DEME-6;KIAA0452 22996 chromosome 1 open reading frame 34 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) RNA-binding region RNP-1 (RNA recognition motif) (IPR000504);TPR-like (IPR008941) high 8.64923080532 200844_s_at PRDX6 1-Cys;AOP2;KIAA0106;MGC46173;NSGPx;PRDX6;PRX;aiPLA2;p29 9588 peroxiredoxin 6 antioxidant activity (GO:0016209);hydrolase activity (GO:0016787);lipid catabolism (GO:0016042);non-selenium glutathione peroxidase activity (GO:0016224);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);peroxidase reaction (GO:0006804);phospholipase A2 activity (GO:0004623);phospholipid catabolism (GO:0009395);response to oxidative stress (GO:0006979) Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (IPR000866) high 8.64476266253 208908_s_at CAST BS-17;CAST;MGC9402 831 calpastatin biological_process unknown (GO:0000004);calpain inhibitor activity (GO:0030161);endopeptidase inhibitor activity (GO:0004866) None high 8.64014715282 220266_s_at KLF4 EZF;GKLF;KLF4 9314 Kruppel-like factor 4 (gut) negative regulation of cell proliferation (GO:0008285);nucleic acid binding (GO:0003676);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcriptional activator activity (GO:0016563);transcriptional repressor activity (GO:0016564);zinc ion binding (GO:0008270) Proline-rich region (IPR000694);Zn-finger, C2H2 type (IPR007087) high 8.63855029403 208906_at BSCL2 BSCL2;GNG3LG;MGC4694;SEIPIN;SPG17 26580 Bernardinelli-Seip congenital lipodystrophy 2 (seipin) None Protein of unknown function DUF1226 (IPR009617) high 8.63528501988 AFFX-HUMRGE/M10098_5_at AFFX-HUMRGE/M10098_5_at None None M10098 Human 18S rRNA gene, complete (_5, _M, _3 represent transcript regions 5 prime, Middle, and 3 prime respectively) None None high 8.63146815972 208893_s_at DUSP6 DUSP6;MKP3;PYST1 1848 dual specificity phosphatase 6 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);MAPKKK cascade (GO:0000165);apoptosis (GO:0006915);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);phosphoprotein phosphatase activity (GO:0004721);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein serine/threonine phosphatase activity (GO:0004722);protein tyrosine phosphatase activity (GO:0004725);protein tyrosine/serine/threonine phosphatase activity (GO:0008138) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 8.62511062324 208791_at CLU APOJ;CLI;CLU;MGC24903;SGP-2;SGP2;SP-40;TRPM-2;TRPM2 1191 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) apoptosis (GO:0006915);cell death (GO:0008219);fertilization (sensu Animalia) (GO:0007338);lipid metabolism (GO:0006629);plasma glycoprotein (GO:0005211) Bipartite nuclear localization signal (IPR001472);Clusterin (IPR000753) high 8.59655724241 206505_at UGT2B4 UGT2B11;UGT2B4 7363 UDP glycosyltransferase 2 family, polypeptide B4 estrogen catabolism (GO:0006711);glucuronosyltransferase activity (GO:0015020);xenobiotic metabolism (GO:0006805) UDP-glucuronosyl/UDP-glucosyltransferase (IPR002213) high 8.58304600631 207883_s_at TFR2 HFE3;TFR2 7036 transferrin receptor 2 iron ion transport (GO:0006826);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);transferrin receptor activity (GO:0004998) Peptidase M28 (IPR007484);Protease-associated PA (IPR003137);Transferrin receptor-like dimerisation domain (IPR007365) high 8.58187981773 214181_x_at LST1 B144;D6S49E;LST-1;LST1 7940 leukocyte specific transcript 1 cellular defense response (GO:0006968);cellular morphogenesis (GO:0000902);defense/immunity protein activity (GO:0003793);immune response (GO:0006955);inflammatory response (GO:0006954);molecular_function unknown (GO:0005554);negative regulation of lymphocyte proliferation (GO:0050672);receptor activity (GO:0004872) LST-1 (IPR007775) high 8.54007177643 215054_at H16758 None None None None None high 8.51750105628 212636_at QKI QK3;QKI 9444 quaking homolog, KH domain RNA binding (mouse) nucleic acid binding (GO:0003676) KH (IPR004087) high 8.50435746681 218081_at C20orf27 C20orf27;FLJ20550 54976 chromosome 20 open reading frame 27 ATP binding (GO:0005524);tRNA aminoacylation for protein translation (GO:0006418);tRNA ligase activity (GO:0004812) None high 8.49048037446 220088_at GPR77 C5A;C5AR;C5L2;C5R1;CD88;GPR77 27202 G protein-coupled receptor 77 C5a anaphylatoxin receptor activity (GO:0004944);G-protein coupled receptor activity, unknown ligand (GO:0016526);G-protein coupled receptor protein signaling pathway (GO:0007186);biological_process unknown (GO:0000004);cellular defense response (GO:0006968);chemotaxis (GO:0006935);immune response (GO:0006955);rhodopsin-like receptor activity (GO:0001584);sensory perception of chemical stimulus (GO:0007606);signal transduction (GO:0007165) Anaphylatoxin chemotactic receptor (IPR002234);Bradykinin receptor (IPR000496);C5A-anaphylatoxin receptor (IPR001274);Formyl/methionyl peptide receptor (IPR000826);Rhodopsin-like GPCR superfamily (IPR000276) high 8.48675074293 213415_at CLIC2 CLIC2;XAP121 1193 chloride intracellular channel 2 chloride channel activity (GO:0005254);chloride transport (GO:0006821);ion transport (GO:0006811);small molecule transport (GO:0006832);transport (GO:0006810);voltage-gated chloride channel activity (GO:0005247) Glutathione S-transferase, N-terminal (IPR004045);Intracellular chloride channel (IPR002946) high 8.48473606084 208891_at DUSP6 DUSP6;MKP3;PYST1 1848 dual specificity phosphatase 6 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);MAPKKK cascade (GO:0000165);apoptosis (GO:0006915);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);phosphoprotein phosphatase activity (GO:0004721);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein serine/threonine phosphatase activity (GO:0004722);protein tyrosine phosphatase activity (GO:0004725);protein tyrosine/serine/threonine phosphatase activity (GO:0008138) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) high 8.4839688724 40850_at FKBP8 FKBP38;FKBP8;FKBPr38 23770 FK506 binding protein 8, 38kDa intracellular signaling cascade (GO:0007242);protein folding (GO:0006457) Peptidylprolyl isomerase, FKBP-type (IPR001179);TPR-like (IPR008941) high 8.47440271065 202014_at PPP1R15A GADD34;PPP1R15A 23645 protein phosphatase 1, regulatory (inhibitor) subunit 15A apoptosis (GO:0006915);response to DNA damage stimulus (GO:0006974) None high 8.4699545308 214370_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 6279 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 8.4691338447 210586_x_at RHCE RH30A;RHC;RHCE;RHE;RHIXB;RHPI;Rh4;RhVI;RhVIII 6006 Rhesus blood group, CcEe antigens ammonium transporter activity (GO:0008519);blood group antigen (GO:0005555);transport (GO:0006810);transporter activity (GO:0005215) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 8.44055173537 204150_at STAB1 FEEL-1;FELE-1;KIAA0246;STAB-1;STAB1 23166 stabilin 1 bacterial binding (GO:0008367);cell adhesion (GO:0007155);cell-cell signaling (GO:0007267);defense response to bacteria (GO:0042742);hyaluronic acid binding (GO:0005540);low-density lipoprotein receptor activity (GO:0005041);protein binding (GO:0005515);protein disulfide oxidoreductase activity (GO:0015035);receptor mediated endocytosis (GO:0006898);scavenger receptor activity (GO:0005044);structural molecule activity (GO:0005198) Beta-Ig-H3/fasciclin (IPR000782);Cytochrome P450 (IPR001128);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Growth factor, receptor (IPR009030);Laminin-type EGF-like domain (IPR002049);Link (IPR000538);Type I EGF (IPR006210) high 8.43514198515 205863_at S100A12 CAAF1;CGRP;ENRAGE;MRP6;S100A12 6283 S100 calcium binding protein A12 (calgranulin C) antifungal peptide activity (GO:0003799);calcium ion binding (GO:0005509);inflammatory response (GO:0006954);xenobiotic metabolism (GO:0006805) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 8.41490978901 37986_at EPOR EPOR 2057 erythropoietin receptor erythropoietin receptor activity (GO:0004900);guanyl-nucleotide exchange factor activity (GO:0005085);intracellular signaling cascade (GO:0007242);neuropeptide signaling pathway (GO:0007218);signal transduction (GO:0007165);small GTPase mediated signal transduction (GO:0007264) Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Guanine-nucleotide dissociation stimulator CDC25 (IPR001895);Long hematopoietin receptor, single chain (IPR003528);Oxidoreductase, molybdopterin binding (IPR000572);RA domain (IPR000159);Ras guanine nucleotide exchange factor (IPR008937) high 8.41197288742 205714_s_at ZMYND10 BLU;FLU;ZMYND10 51364 zinc finger, MYND domain containing 10 None Zn-finger, MYND type (IPR002893) high 8.41164784474 208971_at UROD PCT;UROD 7389 uroporphyrinogen decarboxylase heme biosynthesis (GO:0006783);lyase activity (GO:0016829);uroporphyrinogen decarboxylase activity (GO:0004853) Uroporphyrinogen decarboxylase (URO-D) (IPR000257);Uroporphyrinogen decarboxylase HemE (IPR006361) high 8.40213316752 201904_s_at CTDSPL C3orf8;CTDSPL;HYA22;SCP3 10217 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) NLI interacting factor (IPR004274) high 8.39832284914 204865_at CA3 CA3;CAIII 761 carbonic anhydrase III, muscle specific carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) high 8.39755084942 218872_at TSC FLJ20607;TSC 54997 hypothetical protein FLJ20607 calcium ion binding (GO:0005509) Calcium-binding EF-hand (IPR002048) high 8.39549217968 205268_s_at ADD2 ADD2;ADDB 119 adducin 2 (beta) actin binding (GO:0003779);calmodulin binding (GO:0005516) Bipartite nuclear localization signal (IPR001472);Class II aldolase/adducin, N-terminal (IPR001303);Surface protein from Gram-positive cocci, anchor region (IPR001899) high 8.37962969352 211102_s_at LILRB1 CD85;CD85H;CD85I;CD85J;ILT1;ILT2;LILRA1;LILRA2;LILRB1;LIR-1;LIR-6;LIR-7;LIR1;LIR6;LIR7;MIR-7;MIR7 10859 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 MHC-interacting protein (GO:0003822);antigen binding (GO:0003823);cell surface receptor linked signal transduction (GO:0007166);defense response (GO:0006952);immune response (GO:0006955);protein phosphatase 1 binding (GO:0008157);receptor activity (GO:0004872);response to virus (GO:0009615);signal transduction (GO:0007165);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 8.37612333445 200800_s_at HSPA1A HSP70-1;HSP72;HSPA1;HSPA1A 3303 heat shock 70kDa protein 1A heat shock protein activity (GO:0003773);mRNA catabolism (GO:0006402) Bipartite nuclear localization signal (IPR001472);Heat shock protein Hsp70 (IPR001023) high 8.37044024304 215633_x_at LST1 B144;D6S49E;LST-1;LST1 7940 leukocyte specific transcript 1 cellular defense response (GO:0006968);cellular morphogenesis (GO:0000902);defense/immunity protein activity (GO:0003793);immune response (GO:0006955);inflammatory response (GO:0006954);molecular_function unknown (GO:0005554);negative regulation of lymphocyte proliferation (GO:0050672);receptor activity (GO:0004872) LST-1 (IPR007775) low -4.39792024866 204552_at INPP4A INPP4;INPP4A 3631 inositol polyphosphate-4-phosphatase, type I, 107kDa signal transduction (GO:0007165) C2 calcium/lipid-binding domain, CaLB (IPR008973);C2 domain (IPR000008) low -4.4005572156 209040_s_at PSMB8 D6S216;D6S216E;LMP7;MGC1491;PSMB8;RING10 5696 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) endopeptidase activity (GO:0004175);immune response (GO:0006955);peptidase activity (GO:0008233);proteasome endopeptidase activity (GO:0004299);proteolysis and peptidolysis (GO:0006508);ubiquitin-dependent protein catabolism (GO:0006511) 20S proteasome, A and B subunits (IPR001353);Peptidase T1A, proteasome beta-subunit (IPR000243) low -4.40254578915 214012_at ARTS-1 A-LAP;ALAP;APPILS;ARTS-1;ARTS1;ERAAP;ERAP1;KIAA0525;PILSAP 51752 type 1 tumor necrosis factor receptor shedding aminopeptidase regulator adipocyte differentiation (GO:0045444);aminopeptidase activity (GO:0004177);antigen processing, endogenous antigen via MHC class I (GO:0019885);interleukin-6 receptor binding (GO:0005138);leucyl aminopeptidase activity (GO:0004178);membrane alanyl aminopeptidase activity (GO:0004179);membrane protein ectodomain proteolysis (GO:0006509);metallopeptidase activity (GO:0008237);methionyl aminopeptidase activity (GO:0004239);proteolysis and peptidolysis (GO:0006508);regulation of blood pressure (GO:0008217);tumor necrosis factor receptor binding (GO:0005164);zinc ion binding (GO:0008270) Peptidase M1, membrane alanine aminopeptidase (IPR001930) low -4.40756635604 gnf1h01246_at LOC85028 LOC85028 85028 PNAS-123 None None low -4.41335337126 209670_at Hs.74647 None None CDNA clone MGC:71411 IMAGE:4853814, complete cds MHC protein binding (GO:0042287);immune response (GO:0006955);peptide antigen binding (GO:0042605) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -4.42007712948 gnf1h03933_x_at gnf1h03933_x_at None None None None None low -4.42231161949 207238_s_at PTPRC B220;CD45;GP180;LCA;LY5;PTPRC;T200 5788 protein tyrosine phosphatase, receptor type, C cell surface receptor linked signal transduction (GO:0007166);hydrolase activity (GO:0016787);prenylated protein tyrosine phosphatase activity (GO:0004727);protein amino acid dephosphorylation (GO:0006470);protein tyrosine phosphatase activity (GO:0004725);transmembrane receptor protein tyrosine phosphatase activity (GO:0005001) Fibronectin, type III (IPR003961);Protein tyrosine phosphatase, catalytic region (IPR003595);Tyrosine specific protein phosphatase (IPR000242);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) low -4.42454769566 216560_x_at 216560_x_at None None None None Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin subtype (IPR003599);Immunoglobulin/major histocompatibility complex (IPR003006) low -4.42496368579 206804_at CD3G CD3-GAMMA;CD3G;T3G 917 CD3G antigen, gamma polypeptide (TiT3 complex) T-cell activation (GO:0042110);T-cell receptor activity (GO:0004894);T-cell receptor binding (GO:0042608);cell surface receptor linked signal transduction (GO:0007166);cellular defense response (GO:0006968);development (GO:0007275);establishment and/or maintenance of cell polarity (GO:0007163);protein complex assembly (GO:0006461);protein heterodimerization activity (GO:0046982);protein transport (GO:0015031);receptor signaling complex scaffold activity (GO:0030159);receptor signaling protein activity (GO:0005057);thymocyte differentiation (GO:0046652);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin-like (IPR007110) low -4.44535258481 208754_s_at NAP1L1 MGC23410;MGC8688;NAP1;NAP1L;NAP1L1;NRP 4673 nucleosome assembly protein 1-like 1 DNA binding (GO:0003677);DNA replication (GO:0006260);nucleosome assembly (GO:0006334);positive regulation of cell proliferation (GO:0008284) Bipartite nuclear localization signal (IPR001472);Nucleosome assembly protein (NAP) (IPR002164) low -4.45088174279 201820_at KRT5 CK5;EBS2;KRT5;KRT5A 3852 keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) structural constituent of cytoskeleton (GO:0005200) AMP-dependent synthetase and ligase (IPR000873);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Type II keratin (IPR003054) low -4.47718242733 gnf1h09631_at na None 390928 similar to RIKEN cDNA C330005M16 None None low -4.48770232596 205484_at SIT SIT 27240 SHP2-interacting transmembrane adaptor protein SH3/SH2 adaptor protein activity (GO:0005070);kinase binding (GO:0019900);protein binding (GO:0005515);regulation of T-cell activation (GO:0050863);signal transduction (GO:0007165) None low -4.49156949017 208309_s_at MALT1 DKFZp434L132;MALT1;MLT;MLT1 10892 mucosa associated lymphoid tissue lymphoma translocation gene 1 apoptosis inhibitor activity (GO:0008189);caspase activity (GO:0004199);caspase activity (GO:0030693);defense response (GO:0006952);defense/immunity protein activity (GO:0003793);pathogenesis (GO:0009405);peptidase activity (GO:0008233);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);protein binding (GO:0005515);proteolysis and peptidolysis (GO:0006508);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Caspase-1, p20 (IPR001309);Death domain (IPR000488);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -4.50980360639 221081_s_at FLJ22457 FLJ22457 79961 hypothetical protein FLJ22457 None DENN (AEX-3) domain (IPR001194);dDENN domain (IPR005112);uDENN domain (IPR005113) low -4.51309908218 211645_x_at Hs.512133 None None Isolate donor Z clone Z55K immunoglobulin kappa light chain variable region mRNA, partial cds None None low -4.51397798749 201889_at FAM3C FAM3C;GS3786 10447 family with sequence similarity 3, member C cytokine activity (GO:0005125) None low -4.52390816374 218158_s_at APPL APPL;APPL1;DIP13alpha 26060 adaptor protein containing pH domain, PTB domain and leucine zipper motif 1 cell proliferation (GO:0008283);protein binding (GO:0005515);protein serine/threonine kinase activity (GO:0004674);signal transduction (GO:0007165) Phosphotyrosine interaction domain (IPR006020);Pleckstrin-like (IPR001849) low -4.53857212138 gnf1h08677_at DKFZp761G058 DKFZp761G058 152926 hypothetical protein DKFZp761G058 catalytic activity (GO:0003824);hydrolase activity (GO:0016787);magnesium ion binding (GO:0000287);protein amino acid dephosphorylation (GO:0006470);protein serine/threonine phosphatase activity (GO:0004722) Protein phosphatase (IPR003643);Protein phosphatase 2C subfamily (IPR000222);Protein phosphatase 2C-like (IPR001932) low -4.54100232716 gnf1h06004_at PDE7A HCP1;PDE7A 5150 phosphodiesterase 7A 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);cAMP-specific phosphodiesterase activity (GO:0004115);catalytic activity (GO:0003824);hydrolase activity (GO:0016787);signal transduction (GO:0007165) 3'5'-cyclic nucleotide phosphodiesterase (IPR002073);Metal-dependent phosphohydrolase, HD region (IPR003607) low -4.54221709464 gnf1h11322_at gnf1h11322_at None None None None None low -4.54975288406 213958_at CD6 CD6;TP120 923 CD6 antigen cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);copper ion binding (GO:0005507);immune response (GO:0006955);lymphocyte antigen (GO:0005557);protein binding (GO:0005515);protein-lysine 6-oxidase activity (GO:0004720);scavenger receptor activity (GO:0005044) Speract/scavenger receptor (IPR001190) low -4.55617575277 gnf1h04569_s_at gnf1h04569_s_at None None None None None low -4.55690079006 212068_s_at KIAA0515 KIAA0515;LQFBS-1;MGC10526 84726 KIAA0515 None BAT2, N-terminal (IPR009738) low -4.56250712854 214093_s_at FUBP1 FBP;FUBP;FUBP1 8880 far upstream element (FUSE) binding protein 1 DNA binding (GO:0003677);phosphate transport (GO:0006817);single-stranded DNA binding (GO:0003697);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) KH (IPR004087);KH, type 1 (IPR004088);Proline-rich region (IPR000694) low -4.66211124016 211211_x_at SH2D1A DSHP;EBVS;IMD5;LYP;MTCP1;SAP;SH2D1A;XLP;XLPD 4068 SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome) SH3/SH2 adaptor protein activity (GO:0005070);cell-cell signaling (GO:0007267);cellular defense response (GO:0006968);intracellular signaling cascade (GO:0007242) SH2 motif (IPR000980) low -4.71031788332 215121_x_at Hs.356861 None None CDNA FLJ26905 fis, clone RCT01427, highly similar to Ig lambda chain C regions None Aminoacyl-tRNA synthetase, class I (IPR001412);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -4.75262161247 214677_x_at IGLJ3 IGLJ3;LOC96610 28831 immunoglobulin lambda joining 3 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -4.78491138474 206337_at CCR7 BLR2;CCR7;CDw197;CMKBR7;EBI1 1236 chemokine (C-C motif) receptor 7 C-C chemokine receptor activity (GO:0016493);G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);chemokine receptor activity (GO:0004950);chemotaxis (GO:0006935);inflammatory response (GO:0006954);rhodopsin-like receptor activity (GO:0001584);virulence (GO:0009406) Beta and gamma crystallin (IPR001064);C-C chemokine receptor, type 7 (IPR001718);C-X-C chemokine receptor, type 4 (IPR001277);Chemokine receptor (IPR000355);Rhodopsin-like GPCR superfamily (IPR000276) low -4.78893218264 gnf1h10357_at gnf1h10357_at None None None None None low -4.79379843871 215176_x_at na None 388978 similar to immunoglobulin kappa light chain VC region antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) low -4.81006258949 213460_x_at WBSCR20C DKFZp434K058;FLJ11626;MGC15057;NOL1R2;WBSCR20B;WBSCR20C 260294 Williams Beuren syndrome chromosome region 20C None None low -4.83081470682 204004_at 204004_at None None PRKC, apoptosis, WT1, regulator None None low -4.83322773593 206835_at STATH STATH;STR 6779 statherin extracellular matrix constituent, lubricant activity (GO:0030197);hydroxyapatite binding (GO:0046848);protein binding (GO:0005515);saliva secretion (GO:0046541);structural constituent of tooth enamel (GO:0030345) Statherin (IPR005575) low -4.83475163357 gnf1h06951_at na None 402596 hypothetical gene supported by AK125651; BC039420 None None low -4.84154519858 217529_at BE547674 None None None None None low -4.8416606281 212036_s_at PNN DRS;PNN;SDK3 5411 pinin, desmosome associated protein cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);structural molecule activity (GO:0005198) Bipartite nuclear localization signal (IPR001472);Pinin/SDK (IPR006787);Pinin/SDK/memA protein (IPR006786) low -4.85272015877 213831_at HLA-DQA1 CELIAC1;DQA1;HLA-DQ;HLA-DQA;HLA-DQA1 3117 major histocompatibility complex, class II, DQ alpha 1 MHC class II receptor activity (GO:0045012);antigen presentation, exogenous antigen (GO:0019884);antigen processing, exogenous antigen via MHC class II (GO:0019886);class II major histocompatibility complex antigen (GO:0003821);immune response (GO:0006955);pathogenesis (GO:0009405) Bipartite nuclear localization signal (IPR001472);Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);MHC Class II alpha chain, alpha-1 domain (IPR001003) low -4.87389591003 gnf1h02638_x_at na None 391407 similar to immunoglobulin anti-gp96/grp94 variable region of heavy chain None None low -4.89625609204 219118_at FKBP11 FKBP11;FKBP19 51303 FK506 binding protein 11, 19 kDa FK506-sensitive peptidyl-prolyl cis-trans isomerase (GO:0030051);cyclophilin (GO:0004600);cyclophilin-type peptidyl-prolyl cis-trans isomerase activity (GO:0042027);isomerase activity (GO:0016853);peptidyl-prolyl cis-trans isomerase activity (GO:0003755);protein folding (GO:0006457) Peptidylprolyl isomerase, FKBP-type (IPR001179) low -4.92454739265 200908_s_at RPLP2 RPLP2;RPP2 6181 ribosomal protein, large P2 RNA binding (GO:0003723);protein biosynthesis (GO:0006412);structural constituent of ribosome (GO:0003735) Ribosomal protein 60S (IPR001813) low -4.92477689736 219359_at FLJ22635 FLJ22635 80162 hypothetical protein FLJ22635 None Glycoside hydrolase, family 65, central catalytic (IPR005195);Glycoside transferase, six-hairpin (IPR008928) low -4.93841244736 202431_s_at MYC MYC;c-Myc 4609 v-myc myelocytomatosis viral oncogene homolog (avian) cell proliferation (GO:0008283);iron ion homeostasis (GO:0006879);pathogenesis (GO:0009405);transcription factor activity (GO:0003700);translation regulator activity (GO:0045182) Basic helix-loop-helix dimerization domain bHLH (IPR001092);Leucine zipper, Myc (IPR003327);Transcription regulator Myc (IPR002418) low -4.94950283281 211967_at PORIMIN KCT3;PORIMIN 114908 pro-oncosis receptor inducing membrane injury gene receptor activity (GO:0004872) None low -4.97130341053 220341_s_at LOC51149 LOC51149 51149 truncated calcium binding protein None None low -4.98819309657 205049_s_at CD79A CD79A;IGA;MB-1 973 CD79A antigen (immunoglobulin-associated alpha) cell surface receptor linked signal transduction (GO:0007166);defense response (GO:0006952);transmembrane receptor activity (GO:0004888) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Ribosomal protein S2 (IPR001865) low -5.02164765989 210972_x_at Hs.74647 None None CDNA clone MGC:71411 IMAGE:4853814, complete cds MHC protein binding (GO:0042287);immune response (GO:0006955);peptide antigen binding (GO:0042605) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -5.02808637287 214100_x_at WBSCR20C DKFZp434K058;FLJ11626;MGC15057;NOL1R2;WBSCR20B;WBSCR20C 260294 Williams Beuren syndrome chromosome region 20C None None low -5.03267666901 207826_s_at ID3 HEIR-1;ID3 3399 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein development (GO:0007275);transcription corepressor activity (GO:0003714) Basic helix-loop-helix dimerization domain bHLH (IPR001092) low -5.03662288845 207564_x_at OGT FLJ23071;HRNT1;MGC22921;O-GLCNAC;OGT 8473 O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) O-linked glycosylation (GO:0006493);acetylglucosaminyltransferase activity (GO:0008375);protein binding (GO:0005515);response to nutrients (GO:0007584);signal transduction (GO:0007165);transferase activity, transferring glycosyl groups (GO:0016757) TPR-like (IPR008941) low -5.04016470752 201613_s_at AP1G2 AP1G2;G2AD 8906 adaptor-related protein complex 1, gamma 2 subunit endocytosis (GO:0006897);intracellular protein transport (GO:0006886);protein complex assembly (GO:0006461);protein transporter activity (GO:0008565) ARM repeat fold (IPR008938);Adaptin, N-terminal (IPR002553);Alpha/gamma adaptin, C-terminal (IPR008152);Gamma-adaptin, C-terminal (IPR008153) low -5.05904435745 212589_at RRAS2 RRAS2;TC21 22800 related RAS viral (r-ras) oncogene homolog 2 GTP binding (GO:0005525);GTPase activity (GO:0003924);RAS small monomeric GTPase activity (GO:0003930);cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048);small GTPase mediated signal transduction (GO:0007264) GTP-binding nuclear protein Ran (IPR002041);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -5.08000172606 207339_s_at LTB LTB;TNFC;TNFSF3;p33 4050 lymphotoxin beta (TNF superfamily, member 3) biological_process unknown (GO:0000004);cell-cell signaling (GO:0007267);immune response (GO:0006955);receptor binding (GO:0005102);signal transduction (GO:0007165);toxin activity (GO:0015070);tumor necrosis factor receptor binding (GO:0005164) TNF-like (IPR008983);Tumor Necrosis Factor (IPR006052);Tumor necrosis factor alpha, beta and c (IPR006053);Tumour necrosis factor c/lymphotoxin-beta (IPR002961);Tumour necrosis factor subfamily (IPR003636) low -5.1157870953 210356_x_at MS4A1 Bp35;CD20;LEU-16;MGC3969;MS4A1;MS4A2 931 membrane-spanning 4-domains, subfamily A, member 1 B-cell activation (GO:0042113);G-protein coupled receptor protein signaling pathway (GO:0007186);calcium channel activity (GO:0005262);cell proliferation (GO:0008283);humoral immune response (GO:0006959);immune response (GO:0006955);receptor activity (GO:0004872);receptor signaling protein activity (GO:0005057);signal transduction (GO:0007165) CD20/IgE Fc receptor beta subunit (IPR007237) low -5.11625327738 221580_s_at MGC5306 MGC5306 79101 hypothetical protein MGC5306 None Bipartite nuclear localization signal (IPR001472) low -5.15381829217 204581_at CD22 CD22;SIGLEC-2 933 CD22 antigen antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);lectin (GO:0005530);protein binding (GO:0005515);sugar binding (GO:0005529) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.18511793081 209138_x_at IGL@ IGL;IGL@ 3535 immunoglobulin lambda locus None None low -5.20895780774 gnf1h09389_at na None 402695 similar to 60S ribosomal protein L17 (L23) (Amino acid starvation-induced protein) (ASI) None None low -5.26488203323 209201_x_at CXCR4 CXCR4;D2S201E;HM89;HSY3RR;LAP3;LESTR;NPY3R;NPYR;NPYY3R;WHIM 7852 chemokine (C-X-C motif) receptor 4 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);apoptosis (GO:0006915);chemokine receptor activity (GO:0004950);chemotaxis (GO:0006935);coreceptor activity (GO:0015026);immune response (GO:0006955);inflammatory response (GO:0006954);neurogenesis (GO:0007399);receptor activity (GO:0004872);response to virus (GO:0009615);rhodopsin-like receptor activity (GO:0001584) Angiotensin II receptor (IPR000248);Bradykinin receptor (IPR000496);C-X-C chemokine receptor, type 4 (IPR001277);Chemokine receptor (IPR000355);Immunoglobulin/major histocompatibility complex (IPR003006);Rhodopsin-like GPCR superfamily (IPR000276) low -5.28707520333 gnf1h08048_at na None 200226 similar to Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (PABP 2) None None low -5.34577078974 213670_x_at WBSCR20C DKFZp434K058;FLJ11626;MGC15057;NOL1R2;WBSCR20B;WBSCR20C 260294 Williams Beuren syndrome chromosome region 20C None None low -5.36323178211 211893_x_at CD6 CD6;TP120 923 CD6 antigen cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);copper ion binding (GO:0005507);immune response (GO:0006955);lymphocyte antigen (GO:0005557);protein binding (GO:0005515);protein-lysine 6-oxidase activity (GO:0004720);scavenger receptor activity (GO:0005044) Speract/scavenger receptor (IPR001190) low -5.36895076216 214032_at ZAP70 SRK;STD;TZK;ZAP-70;ZAP70 7535 zeta-chain (TCR) associated protein kinase 70kDa ATP binding (GO:0005524);immune response (GO:0006955);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein kinase cascade (GO:0007243);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -5.37367335765 212538_at DOCK9 DOCK9;KIAA1058;ZIZ1;zizimin1 23348 dedicator of cytokinesis 9 ATP binding (GO:0005524);DNA helicase activity (GO:0003678);DNA replication (GO:0006260);biological_process unknown (GO:0000004);guanyl-nucleotide release factor (GO:0019839) Beta and gamma crystallin (IPR001064);Bipartite nuclear localization signal (IPR001472);Dedicator of cytokinesis (IPR010703);Pleckstrin-like (IPR001849) low -5.38487252843 205890_s_at UBD FAT10;UBD 10537 ubiquitin D antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);polyubiquitin (GO:0005552);protein modification (GO:0006464);proteolysis and peptidolysis (GO:0006508) Ubiquitin (IPR000626) low -5.40842936061 213036_x_at ATP2A3 ATP2A3;SERCA3 489 ATPase, Ca++ transporting, ubiquitous ATP binding (GO:0005524);adenosinetriphosphatase (GO:0004002);calcium ion binding (GO:0005509);calcium ion transport (GO:0006816);calcium-transporting ATPase activity (GO:0005388);cation transport (GO:0006812);hydrolase activity (GO:0016787);hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820);magnesium ion binding (GO:0000287);metabolism (GO:0008152);proton transport (GO:0015992);small molecule transport (GO:0006832);transport (GO:0006810) ATPase, E1-E2 type (IPR001757);Calcium ATPase (IPR005782);Cation transporting ATPase, C-terminal (IPR006068);Cation transporting ATPase, N-terminal (IPR004014);E1-E2 ATPase-associated region (IPR008250);H+ transporting ATPase, proton pump (IPR000695);Haloacid dehalogenase-like hydrolase (IPR005834) low -5.46695516223 202648_at RPS19 DBA;RPS19 6223 ribosomal protein S19 RNA binding (GO:0003723);hemocyte development (GO:0007516);oncogenesis (GO:0007048);protein biosynthesis (GO:0006412);structural constituent of ribosome (GO:0003735) Ribosomal protein S19e (IPR001266);Winged helix DNA-binding (IPR009058) low -5.48385350647 201690_s_at TPD52 D52;N8L;PC-1;PrLZ;TPD52;hD52 7163 tumor protein D52 morphogenesis (GO:0009653) Tumor protein D52 (IPR007327) low -5.48633227147 221601_s_at TOSO TOSO 9214 regulator of Fas-induced apoptosis DNA binding (GO:0003677);apoptosis inhibitor activity (GO:0008189);cellular defense response (GO:0006968);molecular_function unknown (GO:0005554) Bipartite nuclear localization signal (IPR001472);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.5053396989 221691_x_at NPM1 B23;NPM;NPM1 4869 nucleophosmin (nucleolar phosphoprotein B23, numatrin) cell-cell signaling (GO:0007267);growth factor activity (GO:0008083);morphogenesis (GO:0009653);nucleic acid binding (GO:0003676);positive regulation of cell proliferation (GO:0008284);signal transduction (GO:0007165) Cytokine, IL-1 related (IPR008996);Interleukin 1/heparin-binding growth factor (IPR002348);Nucleoplasmin (IPR004301) low -5.53870611274 219117_s_at FKBP11 FKBP11;FKBP19 51303 FK506 binding protein 11, 19 kDa FK506-sensitive peptidyl-prolyl cis-trans isomerase (GO:0030051);cyclophilin (GO:0004600);cyclophilin-type peptidyl-prolyl cis-trans isomerase activity (GO:0042027);isomerase activity (GO:0016853);peptidyl-prolyl cis-trans isomerase activity (GO:0003755);protein folding (GO:0006457) Peptidylprolyl isomerase, FKBP-type (IPR001179) low -5.53893852528 gnf1h07051_s_at gnf1h07051_s_at None None None None Immunoglobulin V-type (IPR003596);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.54818348905 203608_at ALDH5A1 ALDH5A1;SSADH;SSDH 7915 aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) aminobutyrate catabolism (GO:0009450);aminobutyrate metabolism (GO:0009448);dopamine metabolism (GO:0042417);electron transporter activity (GO:0005489);metabolism (GO:0008152);oxidoreductase activity (GO:0016491);succinate-semialdehyde dehydrogenase activity (GO:0004777) Aldehyde dehydrogenase (IPR002086);Bipartite nuclear localization signal (IPR001472) low -5.55519140825 203556_at ZHX2 KIAA0854;ZHX2 22882 zinc fingers and homeoboxes 2 protein binding (GO:0005515);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) Homeobox (IPR001356);Homeodomain-like (IPR009057);Zn-finger, C2H2 type (IPR007087) low -5.5643363522 gnf1h00773_at CARD11 BIMP3;CARD11;CARMA1 84433 caspase recruitment domain family, member 11 apoptosis (GO:0006915);apoptosis regulator activity (GO:0016329);guanylate kinase activity (GO:0004385);intracellular signaling cascade (GO:0007242);protein binding (GO:0005515) CARD interaction domain (IPR001315);Guanylate kinase (IPR008144);PDZ/DHR/GLGF domain (IPR001478) low -5.63680326974 202887_s_at DDIT4 DDIT4;Dig2;FLJ20500;REDD-1;REDD1;RTP801 54541 DNA-damage-inducible transcript 4 None None low -5.63827978714 217028_at CXCR4 CXCR4;D2S201E;HM89;HSY3RR;LAP3;LESTR;NPY3R;NPYR;NPYY3R;WHIM 7852 chemokine (C-X-C motif) receptor 4 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);apoptosis (GO:0006915);chemokine receptor activity (GO:0004950);chemotaxis (GO:0006935);coreceptor activity (GO:0015026);immune response (GO:0006955);inflammatory response (GO:0006954);neurogenesis (GO:0007399);receptor activity (GO:0004872);response to virus (GO:0009615);rhodopsin-like receptor activity (GO:0001584) Angiotensin II receptor (IPR000248);Bradykinin receptor (IPR000496);C-X-C chemokine receptor, type 4 (IPR001277);Chemokine receptor (IPR000355);Immunoglobulin/major histocompatibility complex (IPR003006);Rhodopsin-like GPCR superfamily (IPR000276) low -5.67389003655 201313_at ENO2 ENO2;NSE 2026 enolase 2 (gamma, neuronal) glycolysis (GO:0006096);lyase activity (GO:0016829);magnesium ion binding (GO:0000287);phosphopyruvate hydratase activity (GO:0004634) Enolase (IPR000941) low -5.70251861779 202761_s_at SYNE2 DKFZP434H2235;KIAA1011;NUA;NUANCE;Nesprin-2;SYNE-2;SYNE2 23224 spectrin repeat containing, nuclear envelope 2 actin binding (GO:0003779);protein transport (GO:0015031);receptor activity (GO:0004872);structural molecule activity (GO:0005198) Actin-binding, actinin-type (IPR001589);Binding-protein-dependent transport systems inner membrane component (IPR000515);Bipartite nuclear localization signal (IPR001472);Calponin-like actin-binding (IPR001715);ER lumen protein retaining receptor (IPR000133) low -5.7647708682 218237_s_at SLC38A1 ATA1;NAT2;SAT1;SLC38A1;SNAT1 81539 solute carrier family 38, member 1 amino acid transport (GO:0006865);amino acid-polyamine transporter activity (GO:0005279);neutral amino acid transport (GO:0015804);neutral amino acid transporter activity (GO:0015175);sodium:amino acid transporter activity (GO:0005283) Amino acid/polyamine transporter II (IPR002422) low -5.79404280001 41577_at PPP1R16B ANKRD4;KIAA0823;PPP1R16B;TIMAP 26051 protein phosphatase 1, regulatory (inhibitor) subunit 16B protein phosphatase binding (GO:0019903);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472) low -5.83966512118 212314_at KIAA0746 KIAA0746 23231 KIAA0746 protein None Concanavalin A-like lectin/glucanase (IPR008985) low -5.8862712539 209374_s_at 209374_s_at None None None None Immunoglobulin C-type (IPR003597);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.949180773 212750_at PPP1R16B ANKRD4;KIAA0823;PPP1R16B;TIMAP 26051 protein phosphatase 1, regulatory (inhibitor) subunit 16B protein phosphatase binding (GO:0019903);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472) low -5.98288044899 209671_x_at Hs.74647 None None CDNA clone MGC:71411 IMAGE:4853814, complete cds MHC protein binding (GO:0042287);immune response (GO:0006955);peptide antigen binding (GO:0042605) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -6.01874197752 205668_at LY75 DEC-205;GP200-MR6;LY75 4065 lymphocyte antigen 75 defense/immunity protein activity (GO:0003793);endocytosis (GO:0006897);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);inflammatory response (GO:0006954);lectin (GO:0005530);receptor activity (GO:0004872);sugar binding (GO:0005529) C-type lectin (IPR001304);Ricin B lectin domain (IPR000772);Ricin B-related lectin (IPR008997);Type II fibronectin collagen-binding domain (IPR000562) low -6.02160973805 208798_x_at GOLGIN-67 GOLGA5;GOLGIN-67 23015 golgin-67 None None low -6.02617758872 221602_s_at TOSO TOSO 9214 regulator of Fas-induced apoptosis DNA binding (GO:0003677);apoptosis inhibitor activity (GO:0008189);cellular defense response (GO:0006968);molecular_function unknown (GO:0005554) Bipartite nuclear localization signal (IPR001472);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.02641651172 200791_s_at IQGAP1 HUMORFA01;IQGAP1;KIAA0051;SAR1;p195 8826 IQ motif containing GTPase activating protein 1 GTPase activator activity (GO:0005096);GTPase inhibitor activity (GO:0005095);Ras GTPase activator activity (GO:0005099);calmodulin binding (GO:0005516);protein binding (GO:0005515);signal transduction (GO:0007165);small GTPase mediated signal transduction (GO:0007264) Bipartite nuclear localization signal (IPR001472);Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);IQ calmodulin-binding region (IPR000048);Ras GTPase-activating protein (IPR001936);RasGAP protein, C-terminal (IPR000593);Rho GTPase activation protein (IPR008936);WW/Rsp5/WWP domain (IPR001202) low -6.0921731114 221286_s_at PACAP FLJ32987;PACAP 51237 proapoptotic caspase adaptor protein None None low -6.17926575066 206150_at TNFRSF7 CD27;MGC20393;S152;T14;TNFRSF7;Tp55 939 tumor necrosis factor receptor superfamily, member 7 B-cell proliferation (GO:0042100);DNA binding (GO:0003677);apoptosis (GO:0006915);caspase inhibitor activity (GO:0043027);cell surface receptor linked signal transduction (GO:0007166);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);humoral defense mechanism (sensu Vertebrata) (GO:0016064);immune response (GO:0006955);immunoglobulin secretion (GO:0048305);positive regulation of B-cell differentiation (GO:0045579);positive regulation of T-cell differentiation (GO:0045582);protein binding (GO:0005515);signal transduction (GO:0007165);spermatogenesis (GO:0007283);transmembrane receptor activity (GO:0004888) Fas receptor (IPR008063);TNFR/CD27/30/40/95 cysteine-rich region (IPR001368) low -6.19949774738 217418_x_at MS4A1 Bp35;CD20;LEU-16;MGC3969;MS4A1;MS4A2 931 membrane-spanning 4-domains, subfamily A, member 1 B-cell activation (GO:0042113);G-protein coupled receptor protein signaling pathway (GO:0007186);calcium channel activity (GO:0005262);cell proliferation (GO:0008283);humoral immune response (GO:0006959);immune response (GO:0006955);receptor activity (GO:0004872);receptor signaling protein activity (GO:0005057);signal transduction (GO:0007165) CD20/IgE Fc receptor beta subunit (IPR007237) low -6.26288420007 203828_s_at NK4 NK4 9235 natural killer cell transcript 4 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);defense response (GO:0006952);immune response (GO:0006955) None low -6.28708166529 219812_at STAG3 GATS;MGC2463;STAG3 10734 stromal antigen 3 None ARM repeat fold (IPR008938);Stromal antigen (SA/STAG) protein (IPR005032) low -6.32135489885 215379_x_at IGLJ3 IGLJ3;LOC96610 28831 immunoglobulin lambda joining 3 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.32934280459 217422_s_at CD22 CD22;SIGLEC-2 933 CD22 antigen antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);lectin (GO:0005530);protein binding (GO:0005515);sugar binding (GO:0005529) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.43179760562 217378_x_at 217378_x_at None None None None Immunoglobulin V-type (IPR003596);Immunoglobulin subtype (IPR003599);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.48556473461 210915_x_at M15564 None None None None None low -6.56096101359 215177_s_at ITGA6 CD49f;ITGA6 3655 integrin, alpha 6 cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);cell-substrate junction assembly (GO:0007044);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872) Integrins alpha chain (IPR000413) low -6.58495094799 35974_at LRMP JAW1;LRMP 4033 lymphoid-restricted membrane protein hemocyte development (GO:0007516);vesicle fusion (GO:0006906) MRVI1 (IPR008677) low -6.59771703105 209306_s_at SWAP70 KIAA0640;SWAP-70;SWAP70 23075 SWAP-70 protein calcium ion binding (GO:0005509) Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Pleckstrin-like (IPR001849) low -6.62270216469 211635_x_at Hs.449011 None None Partial mRNA for immunoglobulin heavy chain variable region (IGHV gene), isolate B-CLL G026 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) low -6.70471827614 202988_s_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -6.77307090743 204674_at LRMP JAW1;LRMP 4033 lymphoid-restricted membrane protein hemocyte development (GO:0007516);vesicle fusion (GO:0006906) MRVI1 (IPR008677) low -6.84555480243 209558_s_at HIP1R HIP12;HIP1R;HIP3;KIAA0655 9026 huntingtin interacting protein-1-related actin binding (GO:0003779);biological_process unknown (GO:0000004) Epsin N-terminal homology (IPR001026);I/LWEQ domain (IPR002558);Phosphoinositide-binding clathrin adaptor, N-terminal (IPR008943) low -6.9692555214 205047_s_at ASNS ASNS;TS11 440 asparagine synthetase asparagine biosynthesis (GO:0006529);asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);glutamine metabolism (GO:0006541);ligase activity (GO:0016874);metabolism (GO:0008152) Asparagine synthase (IPR001962);Asparagine synthase, glutamine-hydrolyzing (IPR006426);Glutamine amidotransferase, class-II (IPR000583) low -7.00289519391 205267_at POU2AF1 BOB1;OBF-1;OBF1;OCAB;POU2AF1 5450 POU domain, class 2, associating factor 1 cell growth and/or maintenance (GO:0008151);humoral immune response (GO:0006959);transcription activating factor (GO:0003710);transcription coactivator activity (GO:0003713);transcription cofactor activity (GO:0003712);transcription from Pol II promoter (GO:0006366) Proline-rich region (IPR000694) low -7.05072902083 gnf1h08134_s_at na None 389652 similar to asparagine synthetase; glutamine-dependent asparagine synthetase; TS11 cell cycle control protein None None low -7.13798527174 210258_at RGS13 MGC17173;RGS13 6003 regulator of G-protein signalling 13 signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -7.16305510025 gnf1h01164_at SEPT1 DIFF6;LARP;MGC20394;PNUTL3;SEP1;SEPT1 1731 septin 1 GTP binding (GO:0005525);cytokinesis (GO:0016288) Cell division/GTP binding protein (IPR000038) low -7.16738994598 213856_at CD47 CD47;IAP;MER6;OA3 961 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) cell adhesion molecule activity (GO:0005194);cell-matrix adhesion (GO:0007160);integrin-mediated signaling pathway (GO:0007229);oncogenesis (GO:0007048);plasma glycoprotein (GO:0005211);protein binding (GO:0005515) CD47 integrin associated protein (IPR006704);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -7.17316097033 210538_s_at BIRC3 AIP1;API2;BIRC3;CIAP2;HAIP1;HIAP1;MIHC;RNF49 330 baculoviral IAP repeat-containing 3 apoptosis (GO:0006915);apoptosis inhibitor activity (GO:0008189);cell surface receptor linked signal transduction (GO:0007166);protein binding (GO:0005515) CARD interaction domain (IPR001315);Zn-finger, RING (IPR001841) low -7.22204486768 204960_at PTPRCAP CD45-AP;LPAP;PTPRCAP 5790 protein tyrosine phosphatase, receptor type, C-associated protein antimicrobial peptide activity (GO:0003795);defense response (GO:0006952) None low -7.38947006317 212592_at IGJ IGCJ;IGJ;JCH 3512 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides antigen binding (GO:0003823);immune response (GO:0006955) None low -7.48057688391 204951_at RHOH ARHH;RHOH;TTF 399 ras homolog gene family, member H GTP binding (GO:0005525);GTPase inhibitor activity (GO:0005095);Rho GTPase binding (GO:0017048);Rho small monomeric GTPase activity (GO:0003931);T-cell differentiation (GO:0030217);kinase inhibitor activity (GO:0019210);negative regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043124);oncogenesis (GO:0007048);small GTPase mediated signal transduction (GO:0007264) Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -7.5368174126 206255_at BLK BLK;MGC10442 640 B lymphoid tyrosine kinase ATP binding (GO:0005524);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein kinase cascade (GO:0007243);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -7.55546532343 205671_s_at HLA-DOB HLA-DOB 3112 major histocompatibility complex, class II, DO beta MHC class II receptor activity (GO:0045012);antigen presentation, exogenous antigen (GO:0019884);antigen processing, exogenous antigen via MHC class II (GO:0019886);class II major histocompatibility complex antigen (GO:0003821);immune response (GO:0006955) Class II histocompatibility antigen, beta chain, beta-1 domain (IPR000353);Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -7.60323718559 211634_x_at Hs.449011 None None Partial mRNA for immunoglobulin heavy chain variable region (IGHV gene), isolate B-CLL G026 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) low -8.03327767781 208456_s_at RRAS2 RRAS2;TC21 22800 related RAS viral (r-ras) oncogene homolog 2 GTP binding (GO:0005525);GTPase activity (GO:0003924);RAS small monomeric GTPase activity (GO:0003930);cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048);small GTPase mediated signal transduction (GO:0007264) GTP-binding nuclear protein Ran (IPR002041);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -8.05421222175 201689_s_at TPD52 D52;N8L;PC-1;PrLZ;TPD52;hD52 7163 tumor protein D52 morphogenesis (GO:0009653) Tumor protein D52 (IPR007327) low -8.09179669988 210448_s_at P2RX5 MGC47755;P2RX5;P2X5;P2X5R 5026 purinergic receptor P2X, ligand-gated ion channel, 5 ATP binding (GO:0005524);ion channel activity (GO:0005216);ion transport (GO:0006811);neurogenesis (GO:0007399);receptor activity (GO:0004872);signal transduction (GO:0007165);small molecule transport (GO:0006832);transmembrane receptor activity (GO:0004888);transport (GO:0006810) ATP P2X receptor (IPR001429);P2X5 purinoceptor (IPR003048) low -8.2765485352 216834_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -8.53194857796 201688_s_at TPD52 D52;N8L;PC-1;PrLZ;TPD52;hD52 7163 tumor protein D52 morphogenesis (GO:0009653) Tumor protein D52 (IPR007327) low -8.80539740587 204352_at TRAF5 MGC:39780;RNF84;TRAF5 7188 TNF receptor-associated factor 5 apoptosis (GO:0006915);astacin activity (GO:0008533);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);signal transducer activity (GO:0004871);signal transduction (GO:0007165);zinc ion binding (GO:0008270) MATH (IPR002083);TRAF domain-like (IPR008974);Zn-finger, RING (IPR001841);Zn-finger, TRAF type (IPR001293) low -9.35615249773 211796_s_at 211796_s_at None None None None Immunoglobulin C-type (IPR003597);Immunoglobulin/major histocompatibility complex (IPR003006) low -9.38413749717 205544_s_at CR2 C3DR;CD21;CR2 1380 complement component (3d/Epstein Barr virus) receptor 2 complement receptor activity (GO:0004875);immune response (GO:0006955);transmembrane receptor activity (GO:0004888) Peptidase M14, carboxypeptidase A (IPR000834);Sushi domain/SCR domain/CCP module (IPR000436) low -9.51938476971 204891_s_at LCK LCK 3932 lymphocyte-specific protein tyrosine kinase ATP binding (GO:0005524);RAS protein signal transduction (GO:0007265);cell growth and/or maintenance (GO:0008151);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -9.55301074563 204890_s_at LCK LCK 3932 lymphocyte-specific protein tyrosine kinase ATP binding (GO:0005524);RAS protein signal transduction (GO:0007265);cell growth and/or maintenance (GO:0008151);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -9.5955918469 gnf1h09726_s_at gnf1h09726_s_at None None None None None low -9.87661581838 201189_s_at ITPR3 IP3R3;ITPR3 3710 inositol 1,4,5-triphosphate receptor, type 3 calcium channel activity (GO:0005262);calcium ion transport (GO:0006816);calcium ion transporter activity (GO:0015085);cation transport (GO:0006812);inositol 1\,4\,5-triphosphate-sensitive calcium-release channel activity (GO:0005220);inositol-1,4,5-triphosphate receptor activity (GO:0008095);receptor activity (GO:0004872);signal transduction (GO:0007165);small molecule transport (GO:0006832) Bipartite nuclear localization signal (IPR001472);Ca2+/Na+ channel, pore region (IPR001682);Inositol 1,4,5-trisphosphate-binding protein receptor (IPR000493);Intracellular calcium-release channel (IPR000699);Ion transport protein (IPR005821);Legume lectin, beta domain (IPR001220);MIR domain (IPR003608)