PC-22 p<0.001000 High/Low PC-22 Value ProbeId Name Aliases LocusLink Description Function Protein_Families high 10.5074933426 206446_s_at ELA2A ELA2A 63036 elastase 2A chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);pancreatic elastase II activity (GO:0004281);pancreatic elastase activity (GO:0008132);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 10.3735362933 208498_s_at AMY2A AMY1;AMY1A;AMY2;AMY2A 279 amylase, alpha 2A; pancreatic alpha-amylase activity (GO:0004556);calcium ion binding (GO:0005509);carbohydrate metabolism (GO:0005975);digestion (GO:0007586);hydrolase activity, acting on glycosyl bonds (GO:0016798) Alpha amylase, C-terminal all-beta domain (IPR006048);Alpha amylase, catalytic domain (IPR006047);Alpha amylase, catalytic subdomain (IPR006589);Glycoside hydrolase family 13 (IPR006046) high 10.2822521263 205615_at CPA1 CPA;CPA1 1357 carboxypeptidase A1 (pancreatic) carboxypeptidase A activity (GO:0004182);carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508) Peptidase M14, carboxypeptidase A (IPR000834);Proteinase inhibitor, carboxypeptidase propeptide (IPR003146);Proteinase inhibitor, propeptide (IPR009020) high 10.2379690529 205971_s_at CTRB1 CTRB;CTRB1 1504 chymotrypsinogen B1 chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 9.66488757667 203828_s_at NK4 NK4 9235 natural killer cell transcript 4 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);defense response (GO:0006952);immune response (GO:0006955) None high 9.23560514631 205402_x_at PRSS2 PRSS1;PRSS2;TRP1;TRY1;TRY2;TRY4;TRY8;TRYP1;TRYP2 5645 protease, serine, 2 (trypsin 2) calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 9.16038789248 211766_s_at PNLIPRP2 PLRP2;PNLIPRP2 5408 pancreatic lipase-related protein 2 hydrolase activity (GO:0016787);lipid catabolism (GO:0016042);triacylglycerol lipase activity (GO:0004806);triacylglycerol metabolism (GO:0006641) Esterase/lipase/thioesterase (IPR000379);Lipase (IPR000734);Lipase/lipooxygenase, PLAT/LH2 (IPR008976);Lipoxygenase, LH2 domain (IPR001024);Pancreatic lipase (IPR002331) high 9.00006520035 206311_s_at PLA2G1B PLA2;PLA2A;PLA2G1B;PPLA2 5319 phospholipase A2, group IB (pancreas) actin filament organization (GO:0007015);calcium ion binding (GO:0005509);calcium-dependent cytosolic phospholipase A2 activity (GO:0004627);calcium-dependent secreted phospholipase A2 activity (GO:0004625);calcium-independent cytosolic phospholipase A2 activity (GO:0004628);hydrolase activity (GO:0016787);lipid catabolism (GO:0016042);phospholipase A2 activity (GO:0004623);signal transduction (GO:0007165) Phospholipase A2 (IPR001211) high 8.95635428149 206598_at INS INS 3630 insulin cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);energy pathways (GO:0006091);glucose metabolism (GO:0006006);hormone activity (GO:0005179);insulin receptor binding (GO:0005158);lipid metabolism (GO:0006629);physiological process (GO:0007582) Insulin/IGF/relaxin (IPR004825) high 8.89922883905 206151_x_at ELA3A ELA3;ELA3A 10136 elastase 3A, pancreatic (protease E) cholesterol metabolism (GO:0008203);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);pancreatic elastase I activity (GO:0008125);pancreatic elastase activity (GO:0008132);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 8.81816720934 205869_at PRSS2 PRSS1;PRSS2;TRP1;TRY1;TRY2;TRY4;TRY8;TRYP1;TRYP2 5645 protease, serine, 2 (trypsin 2) calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 8.66752488908 206131_at CLPS CLPS 1208 colipase, pancreatic digestion (GO:0007586);enzyme activator activity (GO:0008047);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629) Colipase (IPR001981) high 8.33660570773 216834_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) high 8.32088398684 205890_s_at UBD FAT10;UBD 10537 ubiquitin D antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);polyubiquitin (GO:0005552);protein modification (GO:0006464);proteolysis and peptidolysis (GO:0006508) Ubiquitin (IPR000626) high 8.32048763122 205912_at PNLIP PNLIP 5406 pancreatic lipase hydrolase activity (GO:0016787);lipid catabolism (GO:0016042);triacylglycerol lipase activity (GO:0004806);triacylglycerol metabolism (GO:0006641) Esterase/lipase/thioesterase (IPR000379);Lipase (IPR000734);Lipase/lipooxygenase, PLAT/LH2 (IPR008976);Lipoxygenase, LH2 domain (IPR001024);Pancreatic lipase (IPR002331) high 8.15501122298 206447_at ELA2A ELA2A 63036 elastase 2A chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);pancreatic elastase II activity (GO:0004281);pancreatic elastase activity (GO:0008132);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 8.07010978876 202833_s_at SERPINA1 A1A;A1AT;AAT;PI1;SERPINA1 5265 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 acute-phase response (GO:0006953);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibititor I4, serpin (IPR000215) high 8.06105366304 212768_s_at GW112 GC1;GW112 10562 differentially expressed in hematopoietic lineages None Latrophilin receptor (IPR003924);Olfactomedin-like (IPR003112) high 7.64445979348 210080_x_at ELA3A ELA3;ELA3A 10136 elastase 3A, pancreatic (protease E) cholesterol metabolism (GO:0008203);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);pancreatic elastase I activity (GO:0008125);pancreatic elastase activity (GO:0008132);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 7.64416919712 205910_s_at CEL BAL;BSDL;BSSL;CEL;CELL;CEase;FAP;FAPP;LIPA 1056 carboxyl ester lipase (bile salt-stimulated lipase) catalytic activity (GO:0003824);cell differentiation (GO:0030154);cell growth (GO:0016049);cholesterol catabolism (GO:0006707);fat-soluble vitamin catabolism (GO:0042363);hydrolase activity (GO:0016787);lipase activity (GO:0016298);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);protein binding (GO:0005515);serine esterase activity (GO:0004759);sterol esterase activity (GO:0004771) Carboxylesterase, type B (IPR002018);Cholinesterase (IPR000997);Esterase/lipase/thioesterase (IPR000379);Proline-rich region (IPR000694) high 7.57469675023 gnf1h09632_at SYCN SYCN;SYL 342898 syncollin None None high 7.55655973238 204073_s_at C11orf9 C11orf9;KIAA0954;MGC10781 745 chromosome 11 open reading frame 9 None Proline-rich region (IPR000694);p53-like transcription factor, DNA-binding (IPR008967) high 7.51745836002 211429_s_at SERPINA1 A1A;A1AT;AAT;PI1;SERPINA1 5265 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 acute-phase response (GO:0006953);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibititor I4, serpin (IPR000215) high 7.3859207087 209752_at REG1A ICRF;MGC12447;P19;PSP;PSPS;PSPS1;PTP;REG;REG1A 5967 regenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic thread protein) lectin (GO:0005530);positive regulation of cell proliferation (GO:0008284);sugar binding (GO:0005529) C-type lectin (IPR001304);Pancreatitis-associated protein (IPR003990);Type II antifreeze protein (IPR002353) high 7.2540424399 gnf1h04772_x_at gnf1h04772_x_at None None None None None high 7.23899687555 206239_s_at SPINK1 PCTT;PSTI;SPINK1;Spink3;TATI 6690 serine protease inhibitor, Kazal type 1 endopeptidase inhibitor activity (GO:0004866);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibitor I1, Kazal (IPR002350);Proteinase inhibitor I1, Kazal metazoa (IPR001239) high 7.21292524363 216470_x_at 216470_x_at None None T cell receptor beta locus None None high 7.20380484643 gnf1h06906_at DKFZp313A2432 DKFZp313A2432 258010 hypothetical protein DKFZp313A2432 None None high 7.18491591359 215395_x_at TRY6 TRY6 154754 trypsinogen C None None high 7.18007478174 201313_at ENO2 ENO2;NSE 2026 enolase 2 (gamma, neuronal) glycolysis (GO:0006096);lyase activity (GO:0016829);magnesium ion binding (GO:0000287);phosphopyruvate hydratase activity (GO:0004634) Enolase (IPR000941) high 7.17528248424 202237_at NNMT NNMT 4837 nicotinamide N-methyltransferase methyltransferase activity (GO:0008168);nicotinamide N-methyltransferase activity (GO:0008112);transferase activity (GO:0016740) Generic methyltransferase (IPR001601);Methyltransferase, NNMT/PNMT/TEMT (IPR000940) high 7.16175868649 201858_s_at PRG1 MGC9289;PPG;PRG;PRG1 5552 proteoglycan 1, secretory granule None Serglycin (IPR007455) high 7.08632223466 220275_at CUZD1 CUZD1;ERG-1;UO-44 50624 CUB and zona pellucida-like domains 1 None CUB (IPR000859);Endoglin/CD105 antigen (IPR001507) high 7.07339808641 211748_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 7.06866124618 205569_at LAMP3 DC-LAMP;DCLAMP;LAMP;LAMP3;TSC403 27074 lysosomal-associated membrane protein 3 cell proliferation (GO:0008283);oncogenesis (GO:0007048) Lysosome-associated membrane glycoprotein (Lamp)/CD68 (IPR002000) high 6.97489315699 200800_s_at HSPA1A HSP70-1;HSP72;HSPA1;HSPA1A 3303 heat shock 70kDa protein 1A heat shock protein activity (GO:0003773);mRNA catabolism (GO:0006402) Bipartite nuclear localization signal (IPR001472);Heat shock protein Hsp70 (IPR001023) high 6.91211270915 gnf1h01013_at C20orf100 C20orf100;MGC15880;dJ1108D11.2;dJ495O3.1 84969 chromosome 20 open reading frame 100 DNA binding (GO:0003677) Beta and gamma crystallin (IPR001064);Bipartite nuclear localization signal (IPR001472);HMG1/2 (high mobility group) box (IPR000910);High mobility group proteins HMG1 and HMG2 (IPR000135);Proline-rich region (IPR000694) high 6.81738216286 205848_at GAS2 GAS2;MGC32610 2620 growth arrest-specific 2 apoptosis (GO:0006915);cell growth and/or maintenance (GO:0008151);cellular morphogenesis (GO:0000902) Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);Growth-arrest-specific protein 2 (IPR003108) high 6.81412329126 211430_s_at IGHG1 IGHG1 3500 immunoglobulin heavy constant gamma 1 (G1m marker) antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 6.66890753521 209396_s_at CHI3L1 CHI3L1;GP39;HC-gp39;HCGP-3P;YKL40 1116 chitinase 3-like 1 (cartilage glycoprotein-39) extracellular matrix structural constituent (GO:0005201);hydrolase activity (GO:0016787);metabolism (GO:0008152) Glycoside hydrolase, family 18 (IPR001223);Sugar transporter superfamily (IPR005829) high 6.6141805511 206422_at GCG GCG;GLP1;GLP2;GRPP 2641 glucagon G-protein coupled receptor protein signaling pathway (GO:0007186);cell proliferation (GO:0008283);feeding behavior (GO:0007631);hormone activity (GO:0005179);peptide hormone (GO:0005180);receptor binding (GO:0005102);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472) high 6.58576864281 202988_s_at RGS1 1R20;BL34;IER1;IR20;RGS1 5996 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) high 6.58532455879 211738_x_at ELA3A ELA3;ELA3A 10136 elastase 3A, pancreatic (protease E) cholesterol metabolism (GO:0008203);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);pancreatic elastase I activity (GO:0008125);pancreatic elastase activity (GO:0008132);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 6.55432154752 214411_x_at CTRB1 CTRB;CTRB1 1504 chymotrypsinogen B1 chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 6.54228597986 209395_at CHI3L1 CHI3L1;GP39;HC-gp39;HCGP-3P;YKL40 1116 chitinase 3-like 1 (cartilage glycoprotein-39) extracellular matrix structural constituent (GO:0005201);hydrolase activity (GO:0016787);metabolism (GO:0008152) Glycoside hydrolase, family 18 (IPR001223);Sugar transporter superfamily (IPR005829) high 6.51020568204 206297_at CTRC CLCR;CTRC 11330 chymotrypsin C (caldecrin) chymotrypsin activity (GO:0004263);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 6.49255287937 gnf1h00312_at ANLN ANILLIN;ANLN;Scraps 54443 anillin, actin binding protein (scraps homolog, Drosophila) actin binding (GO:0003779);septin assembly and septum formation (GO:0000094) Pleckstrin-like (IPR001849) high 6.46868760034 217767_at C3 ASP 718 complement component 3 G-protein coupled receptor protein signaling pathway (GO:0007186);complement activity (GO:0003811);endopeptidase inhibitor activity (GO:0004866);immune response (GO:0006955);inflammatory response (GO:0006954);receptor binding (GO:0005102);signal transduction (GO:0007165) Alpha-2-macroglobulin (IPR001599);Alpha-2-macroglobulin, N-terminal (IPR002890);Alpha-macroglobulin, receptor-binding (IPR009048);Anaphylatoxin/fibulin (IPR000020);Complement C3a/C4a/C5a anaphylatoxin (IPR001840);Netrin, C-terminal (IPR001134);Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (IPR008930) high 6.36563990464 209000_s_at SEPT8 KIAA0202;SEP2;SEPT8 23176 septin 8 None Cell division/GTP binding protein (IPR000038) high 6.32759106702 209072_at MBP MBP 4155 myelin basic protein DNA binding (GO:0003677);immune response (GO:0006955);structural constituent of myelin sheath (GO:0019911);structural molecule activity (GO:0005198) Myelin basic protein (IPR000548) high 6.12142515208 210198_s_at PLP1 MMPL;PLP;PLP/DM20;PLP1;PMD;SPG2 5354 proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) structural molecule activity (GO:0005198) Myelin proteolipid protein PLP (IPR001614) high 6.11733053152 214614_at HLXB9 HB9;HLXB9;HOXHB9;SCRA1 3110 homeo box HB9 RNA polymerase II transcription factor activity (GO:0003702);embryogenesis and morphogenesis (GO:0007345);humoral immune response (GO:0006959);morphogenesis (GO:0009653);transcription factor activity (GO:0003700) Eggshell protein (IPR002952);Homeobox (IPR001356);Homeodomain-like (IPR009057);Orphan nuclear receptor, NOR1 type (IPR003072) high 6.09933868174 214324_at GP2 GP2;ZAP75 2813 glycoprotein 2 (zymogen granule membrane) None EGF-like domain (IPR006209);Endoglin/CD105 antigen (IPR001507) high 6.06054785039 221004_s_at ITM2C BRI3;BRICD2C;E25;E25C;HRPC.1050_D_4;ITM2C;ITM3 81618 integral membrane protein 2C None BRICHOS (IPR007084) high 6.00250515197 212187_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 5.93645103532 217078_s_at CMRF-35H CMRF-35-H9;CMRF-35H;CMRF35H;CMRF35H9;IRC1;IRC2;IRp60 11314 leukocyte membrane antigen receptor activity (GO:0004872) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 5.93217898939 209304_x_at GADD45B DKFZP566B133;GADD45B;GADD45BETA;MYD118 4616 growth arrest and DNA-damage-inducible, beta apoptosis (GO:0006915);response to stress (GO:0006950) Ribosomal protein L7Ae/L30e/S12e/Gadd45 (IPR004038) high 5.90646357781 205886_at REG1B PSPS2;REG1B;REGH;REGI-BETA;REGL 5968 regenerating islet-derived 1 beta (pancreatic stone protein, pancreatic thread protein) cell proliferation (GO:0008283);heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);sugar binding (GO:0005529) C-type lectin (IPR001304);Pancreatitis-associated protein (IPR003990);Type II antifreeze protein (IPR002353) high 5.88761265699 203215_s_at MYO6 DFNA22;DFNB37;KIAA0389;MYO6 4646 myosin VI ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);motor activity (GO:0003774);perception of sound (GO:0007605);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) Bipartite nuclear localization signal (IPR001472);IQ calmodulin-binding region (IPR000048);Myosin head (motor domain) (IPR001609) high 5.87934670742 207620_s_at CASK CASK;LIN2 8573 calcium/calmodulin-dependent serine protein kinase (MAGUK family) ATP binding (GO:0005524);calmodulin binding (GO:0005516);cell adhesion (GO:0007155);guanylate kinase activity (GO:0004385);intracellular signaling cascade (GO:0007242);kinase activity (GO:0016301);membrane-associated guanylate kinase (GO:0004384);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein serine/threonine kinase activity (GO:0004674);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Guanylate kinase (IPR008144);Guanylate kinase/L-type calcium channel region (IPR008145);L27 domain (IPR004172);PDZ/DHR/GLGF domain (IPR001478);Protein kinase (IPR000719);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 5.83312780941 209170_s_at GPM6B GPM6B;M6B 2824 glycoprotein M6B molecular_function unknown (GO:0005554);neurogenesis (GO:0007399) Myelin proteolipid protein PLP (IPR001614) high 5.81414800591 209167_at GPM6B GPM6B;M6B 2824 glycoprotein M6B molecular_function unknown (GO:0005554);neurogenesis (GO:0007399) Myelin proteolipid protein PLP (IPR001614) high 5.79394175913 206681_x_at GP2 GP2;ZAP75 2813 glycoprotein 2 (zymogen granule membrane) None EGF-like domain (IPR006209);Endoglin/CD105 antigen (IPR001507) high 5.7828735658 216598_s_at CCL2 CCL2;GDCF-2;GDCF-2 HC11;HC11;MCAF;MCP-1;MCP1;MGC9434;SCYA2;SMC-CF 6347 chemokine (C-C motif) ligand 2 G-protein coupled receptor protein signaling pathway (GO:0007186);G-protein signaling\, coupled to cyclic nucleotide second messenger (GO:0007187);JAK-STAT cascade (GO:0007259);calcium ion homeostasis (GO:0006874);cell adhesion (GO:0007155);cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);defense response (GO:0006952);histogenesis and organogenesis (GO:0007397);humoral immune response (GO:0006959);inflammatory response (GO:0006954);oncogenesis (GO:0007048);organogenesis (GO:0009887);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);receptor binding (GO:0005102);response to pathogenic bacteria (GO:0009618);response to pest/pathogen/parasite (GO:0009613);signal transducer activity (GO:0004871);signal transduction (GO:0007165);viral replication (GO:0008166) Fractalkine/neurotactin (IPR008097);Small chemokine, C-C subfamily (IPR000827);Small chemokine, interleukin-8 like (IPR001811) high 5.72375694624 210139_s_at PMP22 CMT1A;CMT1E;DSS;GAS-3;HNPP;MGC20769;PMP22;Sp110 5376 peripheral myelin protein 22 mechanosensory behavior (GO:0007638);negative regulation of cell proliferation (GO:0008285);perception of sound (GO:0007605) PMP-22/EMP/MP20 (IPR004032);PMP-22/EMP/MP20 and claudin (IPR004031);Peripheral myelin protein PMP22 (IPR003936) high 5.7130432427 221796_at NTRK2 NTRK2;TRKB 4915 neurotrophic tyrosine kinase, receptor, type 2 ATP binding (GO:0005524);kinase activity (GO:0016301);neurogenesis (GO:0007399);neurotrophin TRKB receptor activity (GO:0005015);neurotrophin binding (GO:0043121);protein amino acid phosphorylation (GO:0006468);receptor activity (GO:0004872);transferase activity (GO:0016740);transmembrane receptor protein tyrosine kinase activity (GO:0004714);transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) Cysteine-rich flanking region, C-terminal (IPR000483);Cysteine-rich flanking region, N-terminal (IPR000372);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Protein kinase (IPR000719);Receptor tyrosine kinase, class II (IPR002011);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 5.67213332392 217953_at PHF3 KIAA0244;PHF3 23469 PHD finger protein 3 DNA binding (GO:0003677);transcription (GO:0006350) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);Transcription elongation factor S-II, central region (IPR003618);Zn-finger-like, PHD finger (IPR001965) high 5.65221678407 gnf1h03776_at gnf1h03776_at None None None None None high 5.62903878016 gnf1h08927_at CLIC6 CLIC1L;CLIC6 54102 chloride intracellular channel 6 chloride transport (GO:0006821);ion transport (GO:0006811);voltage-gated chloride channel activity (GO:0005247) Glutathione S-transferase, C-terminal (IPR004046);Intracellular chloride channel (IPR002946) high 5.62042378096 209987_s_at ASCL1 ASCL1;ASH1;HASH1;MASH1 429 achaete-scute complex-like 1 (Drosophila) cell differentiation (GO:0030154);neurogenesis (GO:0007399);oncogenesis (GO:0007048);transcription factor activity (GO:0003700) Basic helix-loop-helix dimerization domain bHLH (IPR001092);Bipartite nuclear localization signal (IPR001472) high 5.58182390916 210072_at CCL19 CCL19;CKb11;ELC;MGC34433;MIP-3b;MIP3B;SCYA19 6363 chemokine (C-C motif) ligand 19 antiviral response protein activity (GO:0003800);calcium ion homeostasis (GO:0006874);cell communication (GO:0007154);chemokine activity (GO:0008009);chemotaxis (GO:0006935);immune response (GO:0006955);inflammatory response (GO:0006954);response to virus (GO:0009615);signal transduction (GO:0007165) Small chemokine, C-C subfamily (IPR000827);Small chemokine, interleukin-8 like (IPR001811) high 5.57336531305 201631_s_at IER3 DIF-2;DIF2;GLY96;IER3;IEX-1;IEX-1L;IEX1;PRG1 8870 immediate early response 3 apoptosis (GO:0006915);apoptosis inhibitor activity (GO:0008189);cell growth and/or maintenance (GO:0008151);embryogenesis and morphogenesis (GO:0007345);molecular_function unknown (GO:0005554);morphogenesis (GO:0009653) None high 5.57117778547 201525_at APOD APOD 347 apolipoprotein D high-density lipoprotein (GO:0005321);high-density lipoprotein binding (GO:0008035);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transporter activity (GO:0005319);transport (GO:0006810);transporter activity (GO:0005215) Apolipoprotein D (IPR002969);Bacterial lipocalin (IPR002446);Invertebrate colouration protein (IPR003057);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Retinol-binding protein (IPR002449) high 5.56337472548 200799_at HSPA1A HSP70-1;HSP72;HSPA1;HSPA1A 3303 heat shock 70kDa protein 1A heat shock protein activity (GO:0003773);mRNA catabolism (GO:0006402) Bipartite nuclear localization signal (IPR001472);Heat shock protein Hsp70 (IPR001023) high 5.54730038805 207907_at TNFSF14 HVEML;LIGHT;LTg;TNFSF14;TR2 8740 tumor necrosis factor (ligand) superfamily, member 14 T-cell homeostasis (GO:0043029);T-cell proliferation (GO:0042098);caspase inhibitor activity (GO:0043027);immune response (GO:0006955);invasive growth (GO:0007125);receptor binding (GO:0005102);signal transduction (GO:0007165);tumor necrosis factor receptor binding (GO:0005164) TNF-like (IPR008983);Tumor Necrosis Factor (IPR006052);Tumor necrosis factor alpha, beta and c (IPR006053);Tumour necrosis factor subfamily (IPR003636) high 5.53470781717 205509_at CPB1 CPB1;PASP;PCPB 1360 carboxypeptidase B1 (tissue) carboxypeptidase A activity (GO:0004182);carboxypeptidase B activity (GO:0050425);carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508) Peptidase M14, carboxypeptidase A (IPR000834);Proteinase inhibitor, carboxypeptidase propeptide (IPR003146);Proteinase inhibitor, propeptide (IPR009020) high 5.53387304181 215016_x_at BPAG1 BP240;BPA;BPAG1;CATX-15;FLJ13425;FLJ21489;FLJ30627;FLJ32235;KIAA0728 667 bullous pemphigoid antigen 1, 230/240kDa actin binding (GO:0003779);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cytoskeleton organization and biogenesis (GO:0007010);integrin binding (GO:0005178);integrin-mediated signaling pathway (GO:0007229);intermediate filament cytoskeleton organization and biogenesis (GO:0045104);protein C-terminus binding (GO:0008022);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715);Growth-arrest-specific protein 2 (IPR003108);SH3 (IPR001452) high 5.51076118248 202376_at SERPINA3 AACT;ACT;PAI3;PCI;PLANH3;PROCI;SERPINA3;SERPINA5 12 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 DNA binding (GO:0003677);acute-phase response (GO:0006953);chymotrypsin inhibitor activity (GO:0030569);endopeptidase inhibitor activity (GO:0004866);inflammatory response (GO:0006954);plasma glycoprotein (GO:0005211);plasma protein (GO:0005209);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867);serpin (GO:0004868) Proteinase inhibititor I4, serpin (IPR000215) high 5.47986635643 201105_at LGALS1 FLJ21318;GBP;LGALS1;PDXP;PLP;SH3BP1;dJ37E16;dJ37E16.5 3956 lectin, galactoside-binding, soluble, 1 (galectin 1) apoptosis (GO:0006915);galactose binding (GO:0005534);galactose binding lectin (GO:0005531);heterophilic cell adhesion (GO:0007157);hydrolase activity (GO:0016787);lectin (GO:0005530);metabolism (GO:0008152);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871);sugar binding (GO:0005529) 2-phosphoglycolate phosphatase, eukaryotic (IPR006349);Concanavalin A-like lectin/glucanase (IPR008985);Galectin, galactose-binding lectin (IPR001079);HAD-superfamily hydrolase, subfamily IIA (IPR006357);Haloacid dehalogenase-like hydrolase (IPR005834);Proline-rich region (IPR000694);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198) high 5.46427725613 1405_i_at CCL5 CCL5;D17S136E;MGC17164;RANTES;SCYA5;SISd;TCP228 6352 chemokine (C-C motif) ligand 5 antiviral response protein activity (GO:0003800);calcium ion homeostasis (GO:0006874);cell adhesion (GO:0007155);cell motility (GO:0006928);cell-cell signaling (GO:0007267);cellular defense response (GO:0006968);chemokine activity (GO:0008009);chemotaxis (GO:0006935);exocytosis (GO:0006887);immune response (GO:0006955);inflammatory response (GO:0006954);receptor binding (GO:0005102);response to oxidative stress (GO:0006979);response to virus (GO:0009615);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Small chemokine, C-C subfamily (IPR000827);Small chemokine, interleukin-8 like (IPR001811) high 5.41331351185 206694_at PNLIPRP1 PLRP1;PNLIPRP1 5407 pancreatic lipase-related protein 1 catalytic activity (GO:0003824);hydrolase activity (GO:0016787);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);triacylglycerol lipase activity (GO:0004806) Esterase/lipase/thioesterase (IPR000379);Lipase (IPR000734);Lipase/lipooxygenase, PLAT/LH2 (IPR008976);Lipoxygenase, LH2 domain (IPR001024);Pancreatic lipase (IPR002331) high 5.41152596373 205043_at CFTR ABC35;ABCC7;CFTR;MRP7 1080 cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) ATP binding (GO:0005524);ATP-binding and phosphorylation-dependent chloride channel activity (GO:0005224);ATP-binding cassette (ABC) transporter activity (GO:0004009);PDZ domain binding (GO:0030165);adenosinetriphosphatase (GO:0004002);channel-conductance-controlling ATPase activity (GO:0005260);chloride channel activity (GO:0005254);invasive growth (GO:0007125);ion channel activity (GO:0005216);ion transport (GO:0006811);nucleotide binding (GO:0000166);protein binding (GO:0005515);respiratory gaseous exchange (GO:0007585);small molecule transport (GO:0006832);transport (GO:0006810) AAA ATPase (IPR003593);ABC transporter (IPR003439);ABC transporter, transmembrane region (IPR001140);Bipartite nuclear localization signal (IPR001472);Cyclic AMP-dependent chloride channel (IPR005291) high 5.38992471066 204591_at CHL1 CALL;CHL1;L1CAM2 10752 cell adhesion molecule with homology to L1CAM (close homolog of L1) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);signal transduction (GO:0007165) Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 5.37855025339 gnf1h08328_at CKLFSF3 CKLFSF3;FLJ31762;MGC51956 123920 chemokine-like factor super family 3 chemotaxis (GO:0006935);cytokine activity (GO:0005125);transport (GO:0006810);transporter activity (GO:0005215) Marvel (IPR008253) high 5.36084709315 211689_s_at TMPRSS2 PRSS10;TMPRSS2 7113 transmembrane protease, serine 2 chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);scavenger receptor activity (GO:0005044);serine-type peptidase activity (GO:0008236);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003);Speract/scavenger receptor (IPR001190) high 5.3199842916 204345_at COL16A1 447AA;COL16A1 1307 collagen, type XVI, alpha 1 cell adhesion (GO:0007155);collagen (GO:0005202);extracellular matrix structural constituent (GO:0005201);phosphate transport (GO:0006817);pregnancy (GO:0007565) Concanavalin A-like lectin/glucanase (IPR008985);Proline-rich region (IPR000694);Thrombospondin, N-terminal (IPR003129) high 5.31985885284 209774_x_at CXCL2 CINC-2a;CXCL2;GRO2;GROb;MGSA-b;MIP-2a;MIP2;MIP2A;SCYB2 2920 chemokine (C-X-C motif) ligand 2 G-protein coupled receptor protein signaling pathway (GO:0007186);chemokine activity (GO:0008009);chemotaxis (GO:0006935);cytokine activity (GO:0005125);immune response (GO:0006955);inflammatory response (GO:0006954) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) high 5.29609900554 202437_s_at CYP1B1 CP1B;CYP1B1;GLC3A 1545 cytochrome P450, family 1, subfamily B, polypeptide 1 cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);electron transporter activity (GO:0005489);eye morphogenesis (sensu Drosophila) (GO:0007456);eye morphogenesis (sensu Mammalia) (GO:0001747);monooxygenase activity (GO:0004497);oxygen binding (GO:0019825);visual perception (GO:0007601) B-class P450 (IPR002397);Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) high 5.2922660281 33767_at NEFH KIAA0845;NEFH;NFH 4744 neurofilament, heavy polypeptide 200kDa DNA binding (GO:0003677);molecular_function unknown (GO:0005554);neurogenesis (GO:0007399);nucleosome assembly (GO:0006334);structural molecule activity (GO:0005198) Histone H5 (IPR005819);Intermediate filament protein (IPR001664) high 5.28690198372 209309_at AZGP1 AZGP1;ZA2G;ZAG 563 alpha-2-glycoprotein 1, zinc cell adhesion (GO:0007155);fatty acid binding (GO:0005504);immune response (GO:0006955);lipid catabolism (GO:0016042);negative regulation of cell proliferation (GO:0008285);plasma glycoprotein (GO:0005211);protein carrier activity (GO:0008320);ribonuclease activity (GO:0004540) Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Major histocompatibility complex protein, class I (IPR001039) high 5.25043898632 219359_at FLJ22635 FLJ22635 80162 hypothetical protein FLJ22635 None Glycoside hydrolase, family 65, central catalytic (IPR005195);Glycoside transferase, six-hairpin (IPR008928) high 5.24757066983 209686_at S100B NEF;S100;S100B 6285 S100 calcium binding protein, beta (neural) S100 alpha binding (GO:0048155);S100 beta binding (GO:0048154);astrocyte activation (GO:0048143);calcium ion binding (GO:0005509);calcium ion homeostasis (GO:0006874);cell proliferation (GO:0008283);energy reserve metabolism (GO:0006112);hyperphosphorylation (GO:0048151);immune cell activation (GO:0045321);kinase inhibitor activity (GO:0019210);learning and/or memory (GO:0007611);protein binding (GO:0005515);protein homodimerization activity (GO:0042803);tau protein binding (GO:0048156);zinc ion binding (GO:0008270) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 5.23954827321 207077_at ELA2B ELA2B 51032 pancreatic elastase IIB chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);pancreatic elastase II activity (GO:0004281);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 5.20476049527 201951_at ALCAM ALCAM;CD166;MEMD 214 activated leukocyte cell adhesion molecule antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);protein binding (GO:0005515);receptor binding (GO:0005102);signal transduction (GO:0007165) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 5.19126479751 221671_x_at na None 391392 similar to immunoglobulin kappa light chain variable region O11 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) high 5.12174366094 212253_x_at BPAG1 BP240;BPA;BPAG1;CATX-15;FLJ13425;FLJ21489;FLJ30627;FLJ32235;KIAA0728 667 bullous pemphigoid antigen 1, 230/240kDa actin binding (GO:0003779);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cytoskeleton organization and biogenesis (GO:0007010);integrin binding (GO:0005178);integrin-mediated signaling pathway (GO:0007229);intermediate filament cytoskeleton organization and biogenesis (GO:0045104);protein C-terminus binding (GO:0008022);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715);Growth-arrest-specific protein 2 (IPR003108);SH3 (IPR001452) high 5.11482228401 gnf1h07864_s_at LAMA1 LAMA;LAMA1 284217 laminin, alpha 1 cell adhesion (GO:0007155);cell migration (GO:0016477);cell proliferation (GO:0008283);cell-matrix adhesion (GO:0007160);development (GO:0007275);extracellular matrix glycoprotein (GO:0005207);protein binding (GO:0005515);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Galactose-binding like (IPR008979);Laminin B (IPR000034);Laminin G (IPR001791);Laminin, N-terminal (IPR008211);Laminin, N-terminal 2 (IPR008212);Laminin-type EGF-like domain (IPR002049) high 5.10257061061 218663_at HCAP-G CAP-G;CAPG;CHCG;HCAP-G;NY-MEL-3 64151 chromosome condensation protein G None ARM repeat fold (IPR008938);Chromosome condensation protein 3, C-terminal (IPR007283) high 5.088207516 207463_x_at PRSS3 MTG;PRSS3;PRSS4;TRY3;TRY4 5646 protease, serine, 3 (mesotrypsin) calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 5.08280962303 213421_x_at PRSS3 MTG;PRSS3;PRSS4;TRY3;TRY4 5646 protease, serine, 3 (mesotrypsin) calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 5.07876020823 205681_at BCL2A1 BCL2A1;BCL2L5;BFL1;GRS;HBPA1 597 BCL2-related protein A1 apoptosis (GO:0006915);apoptosis inhibitor activity (GO:0008189) Apoptosis regulator Bcl-2 protein, BH (IPR000712);BCL2-like apoptosis inhibitor (IPR002475) high 5.03784807998 209660_at TTR HsT2651;PALB;TBPA;TTR 7276 transthyretin (prealbumin, amyloidosis type I) carrier activity (GO:0005386);retinol binding (GO:0019841);steroid binding (GO:0005496);thyroid hormone generation (GO:0006590);thyroid hormone transporter activity (GO:0015349);transport (GO:0006810) Transthyretin (IPR000895) high 5.02523102187 208473_s_at GP2 GP2;ZAP75 2813 glycoprotein 2 (zymogen granule membrane) None EGF-like domain (IPR006209);Endoglin/CD105 antigen (IPR001507) high 5.01401900889 204439_at C1orf29 C1orf29;GS3686 10964 chromosome 1 open reading frame 29 None None high 4.96529044679 204475_at MMP1 CLG;CLGN;MMP1 4312 matrix metalloproteinase 1 (interstitial collagenase) calcium ion binding (GO:0005509);collagen catabolism (GO:0030574);collagenase activity (GO:0008133);hydrolase activity (GO:0016787);interstitial collagenase activity (GO:0004232);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) Hemopexin (IPR000585);Peptidase M10A and M12B, matrixin and adamalysin (IPR001818);Peptidase, metallopeptidases (IPR006026) high 4.94623472922 207412_x_at CEL BAL;BSDL;BSSL;CEL;CELL;CEase;FAP;FAPP;LIPA 1056 carboxyl ester lipase (bile salt-stimulated lipase) catalytic activity (GO:0003824);cell differentiation (GO:0030154);cell growth (GO:0016049);cholesterol catabolism (GO:0006707);fat-soluble vitamin catabolism (GO:0042363);hydrolase activity (GO:0016787);lipase activity (GO:0016298);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);protein binding (GO:0005515);serine esterase activity (GO:0004759);sterol esterase activity (GO:0004771) Carboxylesterase, type B (IPR002018);Cholinesterase (IPR000997);Esterase/lipase/thioesterase (IPR000379);Proline-rich region (IPR000694) high 4.9298113878 208436_s_at IRF7 IRF7;IRF7A 3665 interferon regulatory factor 7 DNA binding (GO:0003677);inflammatory response (GO:0006954);passive viral induction of host immune response (GO:0046731);response to DNA damage stimulus (GO:0006974);response to virus (GO:0009615);specific RNA polymerase II transcription factor activity (GO:0003704);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcriptional repressor activity (GO:0016564);translation regulator activity (GO:0045182) Interferon regulatory factor (IPR001346);SMAD/FHA (IPR008984);Surface protein from Gram-positive cocci, anchor region (IPR001899) high 4.92901544943 211828_s_at TNIK KIAA0551;TNIK 23043 TRAF2 and NCK interacting kinase ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein kinase cascade (GO:0007243);protein serine/threonine kinase activity (GO:0004674);response to stress (GO:0006950);small GTPase regulatory/interacting protein activity (GO:0005083);transferase activity (GO:0016740) Citron-like (IPR001180);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290) high 4.91605451503 218856_at TNFRSF21 BM-018;DR6;TNFRSF21 27242 tumor necrosis factor receptor superfamily, member 21 apoptosis (GO:0006915);receptor activity (GO:0004872);signal transduction (GO:0007165) Death domain (IPR000488);Four-helical cytokine (IPR009079);TNFR/CD27/30/40/95 cysteine-rich region (IPR001368) high 4.9049217663 210035_s_at RPL5 MSTP030;RPL5 6125 ribosomal protein L5 5S rRNA binding (GO:0008097);RNA binding (GO:0003723);protein biosynthesis (GO:0006412);rRNA binding (GO:0019843);structural constituent of ribosome (GO:0003735) Eukaryotic ribosomal protein L5 (IPR005485);Ribosomal protein L18P/L5E (IPR005484) high 4.90456015794 204384_at GOLGA2 GM130;GOLGA2;MGC20672 2801 golgi autoantigen, golgin subfamily a, 2 None None high 4.88174511792 206691_s_at PDIP ARHGDIG;PDA2;PDI;PDIA2;PDIP;PDIR 64714 protein disulfide isomerase, pancreatic GTPase activator activity (GO:0005096);Rho GDP-dissociation inhibitor activity (GO:0005094);Rho protein signal transduction (GO:0007266);electron transport (GO:0006118);electron transporter activity (GO:0005489);isomerase activity (GO:0016853);negative regulation of cell adhesion (GO:0007162);protein disulfide isomerase activity (GO:0003756);protein folding (GO:0006457);protein-ER retention (GO:0006621) Disulphide isomerase (IPR005788);Immunoglobulin-like (IPR007110);Protein disulphide isomerase (IPR005792);RHO protein GDP dissociation inhibitor (IPR000406);Thioredoxin domain 2 (IPR006663);Thioredoxin type domain (IPR006662) high 4.87665638786 gnf1h05980_at KIF21A CFEOM1;FEOM1;FLJ20052;KIAA1708;KIF21A 55605 kinesin family member 21A ATP binding (GO:0005524);microtubule-based process (GO:0007017);motor activity (GO:0003774) Bipartite nuclear localization signal (IPR001472);Kinesin, motor region (IPR001752) high 4.86814175716 37004_at SFTPB PSP-B;SFTB3;SFTP3;SFTPB;SP-B 6439 surfactant, pulmonary-associated protein B histogenesis and organogenesis (GO:0007397);lipid metabolism (GO:0006629);organogenesis (GO:0009887);regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);sphingolipid metabolism (GO:0006665);surfactant activity (GO:0019214) Saposin (IPR008373);Saposin B (IPR008139);Saposin B subdomain (IPR008140);Saposin type A (IPR003119);Saposin-like type B, 1 (IPR007856);Saposin-like type B, 2 (IPR008138);Surfactant protein B (IPR008137) high 4.85882243007 208747_s_at C1S C1S 716 complement component 1, s subcomponent calcium ion binding (GO:0005509);chymotrypsin activity (GO:0004263);complement component C1s activity (GO:0003816);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);serine-type peptidase activity (GO:0008236);trypsin activity (GO:0004295) CUB (IPR000859);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003);Sushi domain/SCR domain/CCP module (IPR000436) high 4.82954825975 205815_at PAP HIP;INGAP;PAP;PAP-H;PAP1;REG-III 5068 pancreatitis-associated protein acute-phase response (GO:0006953);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);cell growth (GO:0016049);cell proliferation (GO:0008283);development (GO:0007275);growth factor activity (GO:0008083);hematopoietin/interferon-class (D200-domain) cytokine receptor activity (GO:0004896);heterophilic cell adhesion (GO:0007157);inflammatory response (GO:0006954);lectin (GO:0005530);sugar binding (GO:0005529) C-type lectin (IPR001304);Pancreatitis-associated protein (IPR003990) high 4.80590720371 202806_at DBN1 D0S117E;DBN1;DKFZp434D064 1627 drebrin 1 actin binding (GO:0003779);actin filament organization (GO:0007015);neurogenesis (GO:0007399);profilin binding (GO:0005522) Actin-binding, cofilin/tropomyosin type (IPR002108);Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694) high 4.80540655372 206187_at PTGIR PRIPR;PTGIR 5739 prostaglandin I2 (prostacyclin) receptor (IP) G-protein coupled receptor protein signaling pathway (GO:0007186);G-protein signaling\, coupled to cyclic nucleotide second messenger (GO:0007187);cell-cell signaling (GO:0007267);prostaglandin I receptor activity (GO:0004959);receptor activity (GO:0004872);rhodopsin-like receptor activity (GO:0001584);thromboxane receptor activity (GO:0004960) Prostacyclin (prostanoid IP) receptor (IPR000370);Prostanoid receptor (IPR008365);Rhodopsin-like GPCR superfamily (IPR000276);Thromboxane receptor (IPR001105) high 4.78259541704 202291_s_at MGP MGLAP;MGP;NTI 4256 matrix Gla protein calcium ion binding (GO:0005509);extracellular matrix structural constituent (GO:0005201);oncogenesis (GO:0007048);perception of sound (GO:0007605);structural constituent of bone (GO:0008147) Bone matrix, Gla region (IPR002384);Vitamin K-dependent carboxylation/gamma-carboxyglutamic region (IPR000294) high 4.78102134084 214464_at CDC42BPA CDC42BPA;FLJ23347;KIAA0451;MRCK;MRCKA;PK428 8476 CDC42 binding protein kinase alpha (DMPK-like) ATP binding (GO:0005524);intracellular signaling cascade (GO:0007242);kinase activity (GO:0016301);protein amino acid phosphorylation (GO:0006468);protein serine/threonine kinase activity (GO:0004674);small GTPase regulatory/interacting protein activity (GO:0005083) Bipartite nuclear localization signal (IPR001472);C-type lectin (IPR001304);Citron-like (IPR001180);PAK-box/P21-Rho-binding (IPR000095);Pleckstrin-like (IPR001849);Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 4.77940406167 221651_x_at na None 391392 similar to immunoglobulin kappa light chain variable region O11 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) high 4.77173877806 gnf1h07482_s_at CGI-69 CGI-69 51629 CGI-69 protein binding (GO:0005488);transport (GO:0006810) Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993) high 4.76236946179 219279_at DOCK10 DOCK10;FLJ20220;KIAA0694;ZIZ3 55619 dedicator of cytokinesis 10 None Pleckstrin-like (IPR001849) high 4.76029482239 203824_at TM4SF3 CO-029;TM4SF3 7103 transmembrane 4 superfamily member 3 pathogenesis (GO:0009405);protein amino acid glycosylation (GO:0006486);signal transducer activity (GO:0004871);tumor antigen (GO:0008222) CD9/CD37/CD63 antigen (IPR000301) high 4.7515112327 gnf1h07863_at LAMA1 LAMA;LAMA1 284217 laminin, alpha 1 cell adhesion (GO:0007155);cell migration (GO:0016477);cell proliferation (GO:0008283);cell-matrix adhesion (GO:0007160);development (GO:0007275);extracellular matrix glycoprotein (GO:0005207);protein binding (GO:0005515);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Galactose-binding like (IPR008979);Laminin B (IPR000034);Laminin G (IPR001791);Laminin, N-terminal (IPR008211);Laminin, N-terminal 2 (IPR008212);Laminin-type EGF-like domain (IPR002049) high 4.74316818786 203571_s_at C10orf116 APM2;C10orf116 10974 chromosome 10 open reading frame 116 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) None high 4.71094073577 211663_x_at PTGDS PDS;PGD2;PGDS;PGDS2;PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) isomerase activity (GO:0016853);prostaglandin biosynthesis (GO:0001516);prostaglandin-D synthase activity (GO:0004667);regulation of circadian sleep/wake cycle, sleep (GO:0045187);retinoid binding (GO:0005501);transport (GO:0006810);transporter activity (GO:0005215) Alpha-1-microglobulin (IPR002968);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Mus/Rat 1 allergen (IPR002971);Neutrophil gelatinase-associated lipocalin (IPR003087);Prostaglandin D synthase (IPR002972) high 4.7017942321 209875_s_at SPP1 BNSP;BSPI;ETA-1;OPN;SPP1 6696 secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) T-helper 1 type immune response (GO:0042088);cell-cell signaling (GO:0007267);cell-matrix adhesion (GO:0007160);cytokine activity (GO:0005125);growth factor activity (GO:0008083);immune cell chemotaxis (GO:0030595);integrin binding (GO:0005178);positive regulation of T-cell proliferation (GO:0042102);protein binding (GO:0005515);regulation of myeloid blood cell differentiation (GO:0045637);skeletal development (GO:0001501) Osteopontin (IPR002038) high 4.68761400335 204827_s_at CCNF CCNF;FBX1;FBXO1 899 cyclin F cyclin-dependent protein kinase regulator activity (GO:0016538);cytokinesis (GO:0016288) Cyclin (IPR006670);Cyclin, C-terminal (IPR004367);Cyclin, N-terminal (IPR006671);Cyclin-like F-box (IPR001810) high 4.68202184412 210916_s_at CD44 CD44;CDW44;ECMR-III;INLU;LHR;MC56;MDU2;MDU3;MGC10468;MIC4;MUTCH-I;Pgp1 960 CD44 antigen (homing function and Indian blood group system) cell adhesion (GO:0007155);cell-cell adhesion (GO:0016337);cell-matrix adhesion (GO:0007160);collagen binding (GO:0005518);hyaluronic acid binding (GO:0005540);receptor activity (GO:0004872) CD44 antigen (IPR001231);Link (IPR000538) high 4.6752126322 gnf1h06568_s_at LOC400451 LOC400451 400451 hypothetical gene supported by AK075564; BC060873 None None high 4.66109056351 205825_at PCSK1 NEC1;PC1;PC3;PCSK1;SPC3 5122 proprotein convertase subtilisin/kexin type 1 cell-cell signaling (GO:0007267);hydrolase activity (GO:0016787);metabolism (GO:0008152);proprotein convertase 1 activity (GO:0004285);proteolysis and peptidolysis (GO:0006508);subtilase activity (GO:0004289) Peptidase S8 and S53, subtilisin, kexin, sedolisin (IPR000209);Proprotein convertase, P domain (IPR002884);Proteinase inhibitor, propeptide (IPR009020) high 4.65914921338 gnf1h03798_s_at LOC129642 LOC129642 129642 hypothetical protein BC016005 None Membrane bound O-acyl transferase, MBOAT (IPR004299) high 4.64220820023 212354_at SULF1 HSULF-1;KIAA1077;SULF-1;SULF1 23213 sulfatase 1 apoptosis (GO:0006915);arylsulfatase activity (GO:0004065);heparan sulfate proteoglycan metabolism (GO:0030201);hydrolase activity (GO:0016787);metabolism (GO:0008152);sulfuric ester hydrolase activity (GO:0008484) Sulfatase (IPR000917) high 4.63510360193 208543_at OR10H2 OR10H2 26538 olfactory receptor, family 10, subfamily H, member 2 G-protein coupled receptor protein signaling pathway (GO:0007186);olfactory receptor activity (GO:0004984);perception of smell (GO:0007608) Rhodopsin-like GPCR superfamily (IPR000276) high 4.63176399071 220483_s_at RNF19 DKFZp566B1346;DORFIN;RNF19 25897 ring finger protein 19 microtubule cytoskeleton organization and biogenesis (GO:0000226);protein modification (GO:0006464);transcription factor binding (GO:0008134);zinc ion binding (GO:0008270) Bipartite nuclear localization signal (IPR001472);Zn-finger, RING (IPR001841);Zn-finger, cysteine-rich C6HC (IPR002867) high 4.63144134125 207165_at HMMR HMMR;RHAMM 3161 hyaluronan-mediated motility receptor (RHAMM) cell motility (GO:0006928);hyaluronic acid binding (GO:0005540);oncogenesis (GO:0007048) None high 4.63092836658 209183_s_at C10orf10 C10orf10;DEPP;FIG 11067 chromosome 10 open reading frame 10 DNA binding (GO:0003677) None high 4.61906376891 219584_at PLA1A PLA1A;PS-PLA1;PSPLA1 51365 phospholipase A1 member A catalytic activity (GO:0003824);lipid metabolism (GO:0006629);phosphatidylserine metabolism (GO:0006658);phospholipase A1 activity (GO:0008970) Esterase/lipase/thioesterase (IPR000379);Lipase (IPR000734) high 4.61536068544 201601_x_at IFITM1 9-27;CD225;IFI17;IFITM1;LEU13 8519 interferon induced transmembrane protein 1 (9-27) cell surface receptor linked signal transduction (GO:0007166);immune response (GO:0006955);negative regulation of cell proliferation (GO:0008285);receptor signaling protein activity (GO:0005057);response to biotic stimulus (GO:0009607) Interferon-induced transmembrane protein (IPR007593) high 4.61390758488 gnf1h07199_at BPAG1 BP240;BPA;BPAG1;CATX-15;FLJ13425;FLJ21489;FLJ30627;FLJ32235;KIAA0728 667 bullous pemphigoid antigen 1, 230/240kDa actin binding (GO:0003779);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cytoskeleton organization and biogenesis (GO:0007010);integrin binding (GO:0005178);integrin-mediated signaling pathway (GO:0007229);intermediate filament cytoskeleton organization and biogenesis (GO:0045104);protein C-terminus binding (GO:0008022);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715);Growth-arrest-specific protein 2 (IPR003108);SH3 (IPR001452) high 4.61262085232 209832_s_at CDT1 CDT1;DUP 81620 DNA replication factor DNA binding (GO:0003677) Regulator of chromosome condensation, RCC1 (IPR000408) high 4.60823671888 213721_at SOX2 ANOP3;MGC2413;SOX2 6657 SRY (sex determining region Y)-box 2 RNA polymerase II transcription factor activity, enhancer binding (GO:0003705);establishment and/or maintenance of chromatin architecture (GO:0006325);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) HMG1/2 (high mobility group) box (IPR000910) high 4.59417042489 210677_at SOAT2 ACACT2;ACAT2;ARGP2;SOAT2 8435 sterol O-acyltransferase 2 acyltransferase activity (GO:0008415);cholesterol metabolism (GO:0008203);sterol O-acyltransferase activity (GO:0004772);transferase activity (GO:0016740) Membrane bound O-acyl transferase, MBOAT (IPR004299) high 4.59338799461 gnf1h10803_s_at gnf1h10803_s_at None None None None Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314) high 4.59055609651 217546_at MT1K MGC40498;MT1;MT1K;MT1M 4499 metallothionein 1K metal ion binding (GO:0046872) Growth factor, cystine knot (IPR002400);Metallothionein superfamily (IPR003019);Vertebrate metallothionein (IPR000006);Whey acidic protein, core region (IPR008197) high 4.58617096376 207468_s_at SFRP5 SARP3;SFRP5 6425 secreted frizzled-related protein 5 apoptosis (GO:0006915);development (GO:0007275);embryogenesis and morphogenesis (GO:0007345);establishment and/or maintenance of cell polarity (GO:0007163);morphogenesis (GO:0009653);signal transduction (GO:0007165);transmembrane receptor activity (GO:0004888);visual perception (GO:0007601) Bipartite nuclear localization signal (IPR001472);Frizzled CRD region (IPR000024);Netrin, C-terminal (IPR001134);TIMP-like OB-fold (IPR008993) high 4.57523670179 209921_at SLC7A11 CCBR1;SLC7A11;xCT 23657 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 amino acid permease activity (GO:0015359);amino acid transport (GO:0006865);cystine:glutamate antiporter activity (GO:0015327);protein complex assembly (GO:0006461);transport (GO:0006810) Amino acid permease-associated region (IPR004841);Amino acid/polyamine transporter I (IPR002293);L-type amino acid transporter (IPR004760) high 4.57225402899 207325_x_at MAGEA1 MAGE1;MAGEA1;MGC9326 4100 melanoma antigen, family A, 1 (directs expression of antigen MZ2-E) tumor antigen (GO:0008222) Bipartite nuclear localization signal (IPR001472);MAGE protein (IPR002190) high 4.56078118924 219594_at NINJ2 NINJ2 4815 ninjurin 2 cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);neurogenesis (GO:0007399);neuronal cell adhesion (GO:0007158) Ninjurin (IPR007007) high 4.55950912891 gnf1h05368_s_at CUZD1 CUZD1;ERG-1;UO-44 50624 CUB and zona pellucida-like domains 1 None CUB (IPR000859);Endoglin/CD105 antigen (IPR001507) high 4.54989835148 221618_s_at TAF9L DN-7;DN7;TAF9L;TAFII31L;TFIID-31 51616 TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa DNA binding (GO:0003677) Histone-fold (IPR009072);Histone-fold/TFIID-TAF/NF-Y (IPR007124);Transcription factor TAFII-31 (IPR003162) high 4.54428950646 gnf1h07301_s_at na None 399747 similar to hypothetical protein FLJ40432 None None high 4.53908741305 gnf1h05261_at FRMD4 FLJ10210;FRMD4;KIAA1294;bA295P9.4 55691 FERM domain containing 4 cytoskeletal protein binding (GO:0008092) Band 4.1 (IPR000299);Bipartite nuclear localization signal (IPR001472);Ezrin/radixin/moesin ERM (IPR000798);FERM (IPR009065) high 4.5371712704 206480_at LTC4S LTC4S;MGC33147 4056 leukotriene C4 synthase enzyme activator activity (GO:0008047);glutathione conjugation reaction (GO:0006803);glutathione transferase activity (GO:0004364);leukotriene biosynthesis (GO:0019370);leukotriene-C4 synthase activity (GO:0004464);transferase activity (GO:0016740) 5-lipoxygenase-activating protein (IPR001446);Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) (IPR001129) high 4.53400458953 209392_at ENPP2 ATX;ENPP2;LysoPLD;PD-IALPHA;PDNP2 5168 ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) G-protein coupled receptor protein signaling pathway (GO:0007186);cell motility (GO:0006928);chemotaxis (GO:0006935);endonuclease activity (GO:0004519);hydrolase activity (GO:0016787);nucleic acid binding (GO:0003676);nucleotide diphosphatase activity (GO:0004551);nucleotide metabolism (GO:0009117);phosphate metabolism (GO:0006796);phosphodiesterase I activity (GO:0004528);transcription factor binding (GO:0008134) Bipartite nuclear localization signal (IPR001472);DNA/RNA non-specific endonuclease (IPR001604);Somatomedin B (IPR001212);Type I phosphodiesterase/nucleotide pyrophosphatase (IPR002591) high 4.5319980802 203400_s_at TF PRO1557;PRO2086 7018 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 4.53019821009 215176_x_at na None 388978 similar to immunoglobulin kappa light chain VC region antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) high 4.52881849137 212738_at ARHGAP19 ARHGAP19;FLJ00194;MGC14258 84986 Rho GTPase activating protein 19 None Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198) high 4.52576517131 205989_s_at MOG MGC26137;MOG 4340 myelin oligodendrocyte glycoprotein None Immunoglobulin V-type (IPR003596);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 4.52566495449 gnf1h09053_at FMNL2 FHOD2;FMNL2;KIAA1902 114793 formin-like 2 actin binding (GO:0003779);cytokinesis (GO:0016288);transcription factor activity (GO:0003700) Actin-binding FH2 (IPR003104);Bipartite nuclear localization signal (IPR001472);Diaphanous FH3 (IPR010472);Diaphanous GTPase-binding (IPR010473);Phage protein, HK97, gp10 (IPR010064);Proline-rich region (IPR000694);Wilm's tumour protein (IPR000976) high 4.52557391483 gnf1h10214_at gnf1h10214_at None None (LG6770) None None high 4.52260135758 207323_s_at MBP MBP 4155 myelin basic protein DNA binding (GO:0003677);immune response (GO:0006955);structural constituent of myelin sheath (GO:0019911);structural molecule activity (GO:0005198) Myelin basic protein (IPR000548) high 4.52163290108 215733_x_at CTAG2 CAMEL;CTAG2;ESO2;LAGE-1;LAGE-1L;LAGE-1S;LAGE-1a;LAGE-1b;LAGE-2b;LAGE1;MGC3803 30848 cancer/testis antigen 2 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) None high 4.52067126133 211735_x_at SFTPC PSP-C;SFTP2;SFTPC;SP-C 6440 surfactant, pulmonary-associated protein C regulation of liquid surface tension (GO:0050828);respiratory gaseous exchange (GO:0007585);surfactant activity (GO:0019214) BRICHOS (IPR007084);Surfactant-associated polypeptide (IPR001729) high 4.51827036576 206755_at CYP2B6 CPB6;CYP2B;CYP2B6;CYPIIB6;IIB1;P450 1555 cytochrome P450, family 2, subfamily B, polypeptide 6 cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);monooxygenase activity (GO:0004497);oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced flavin or flavoprotein as one donor\, and incorporation of one atom of oxygen (GO:0016712) Cytochrome P450 (IPR001128);E-class P450, CYP2B (IPR008068);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) high 4.51229002588 212254_s_at BPAG1 BP240;BPA;BPAG1;CATX-15;FLJ13425;FLJ21489;FLJ30627;FLJ32235;KIAA0728 667 bullous pemphigoid antigen 1, 230/240kDa actin binding (GO:0003779);calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cytoskeleton organization and biogenesis (GO:0007010);integrin binding (GO:0005178);integrin-mediated signaling pathway (GO:0007229);intermediate filament cytoskeleton organization and biogenesis (GO:0045104);protein C-terminus binding (GO:0008022);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715);Growth-arrest-specific protein 2 (IPR003108);SH3 (IPR001452) high 4.51214133854 204036_at EDG2 EDG2;Gpcr26;LPA1;LPAR1;Mrec1.3;edg-2;rec.1.3;vzg-1 1902 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);lysosphingolipid and lysophosphatidic acid receptor activity (GO:0001619);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871) EDG-2 lysophosphatidic acid receptor (IPR002277);Lysophosphatidic acid receptor (IPR004065);Melanocortin receptor family (IPR001671);Rhodopsin-like GPCR superfamily (IPR000276) high 4.49385704971 215051_x_at AIF1 AIF-1;AIF1;IBA1;IRT-1 199 allograft inflammatory factor 1 calcium ion binding (GO:0005509);inflammatory response (GO:0006954);negative regulation of cell proliferation (GO:0008285);response to stress (GO:0006950) Calcium-binding EF-hand (IPR002048) high 4.49267761387 219505_at CECR1 CECR1 51816 cat eye syndrome chromosome region, candidate 1 deaminase activity (GO:0019239);development (GO:0007275);growth factor activity (GO:0008083);hydrolase activity (GO:0016787);hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);nucleotide metabolism (GO:0009117);purine ribonucleoside monophosphate biosynthesis (GO:0009168) Adenosine deaminase-related growth factor (IPR006331);Adenosine/AMP deaminase (IPR001365) high 4.48954833578 205568_at AQP9 AQP9;HsT17287;SSC1 366 aquaporin 9 immune response (GO:0006955);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215);water channel activity (GO:0015250);water transport (GO:0006833) Major intrinsic protein (IPR000425) high 4.48343617002 205111_s_at PLCE1 KIAA1516;PLCE;PLCE1 51196 phospholipase C, epsilon 1 RAS protein signal transduction (GO:0007265);Ras interactor activity (GO:0017016);calcium-mediated signaling (GO:0019722);cell proliferation (GO:0008283);cytoskeleton organization and biogenesis (GO:0007010);diacylglycerol biosynthesis (GO:0006651);enzyme binding (GO:0019899);epidermal growth factor receptor signaling pathway (GO:0007173);guanyl-nucleotide exchange factor activity (GO:0005085);heart development (GO:0007507);inositol phosphate-mediated signaling (GO:0048016);intracellular signaling cascade (GO:0007242);lipid metabolism (GO:0006629);neuropeptide signaling pathway (GO:0007218);phosphoinositide phospholipase C activity (GO:0004435);phospholipid metabolism (GO:0006644);protein binding (GO:0005515);receptor signaling protein activity (GO:0005057);regulation of G-protein coupled receptor protein signaling pathway (GO:0008277);regulation of cell growth (GO:0001558);regulation of protein kinase activity (GO:0045859);small GTPase mediated signal transduction (GO:0007264) C2 calcium/lipid-binding domain, CaLB (IPR008973);C2 domain (IPR000008);Guanine-nucleotide dissociation stimulator CDC25 (IPR001895);Phosphatidylinositol-specific phospholipase C, X domain (IPR000909);Phosphatidylinositol-specific phospholipase C, Y domain (IPR001711);Phosphoinositide-specific phospholipase C (PLC) (IPR001192);RA domain (IPR000159);Ras guanine nucleotide exchange factor (IPR008937) high 4.48067718919 201291_s_at TOP2A TOP2;TOP2A;TP2A 7153 topoisomerase (DNA) II alpha 170kDa ATP binding (GO:0005524);DNA binding (GO:0003677);DNA metabolism (GO:0006259);DNA topoisomerase (ATP-hydrolyzing) activity (GO:0003918);DNA topoisomerase activity (GO:0003916);isomerase activity (GO:0016853) ATP-binding region, ATPase-like (IPR003594);Bipartite nuclear localization signal (IPR001472);DNA gyrase/topoisomerase IV, subunit A (IPR002205);DNA topoisomerase II (IPR001241);Histone-like transcription factor/archaeal histone/topoisomerase (IPR003957);Topoisomerase II (IPR001154) high 4.45529188229 218687_s_at MUC13 DRCC1;FLJ20063;MUC13 56667 mucin 13, epithelial transmembrane None EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);SEA (IPR000082);Type I EGF (IPR006210) high 4.45244711495 206915_at NKX2-2 NKX2-2;NKX2.2;NKX2B 4821 NK2 transcription factor related, locus 2 (Drosophila) development (GO:0007275);transcription factor activity (GO:0003700) Homeobox (IPR001356) high 4.44243969654 213915_at NKG7 GIG1;NKG7 4818 natural killer cell group 7 sequence None PMP-22/EMP/MP20 (IPR004032);PMP-22/EMP/MP20 and claudin (IPR004031) high 4.43940355959 gnf1h01546_s_at Hs.523212 None None Transcribed sequence None None high 4.43715475171 206212_at CPA2 CPA2 1358 carboxypeptidase A2 (pancreatic) carboxypeptidase A activity (GO:0004182);carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508);vacuolar protein catabolism (GO:0007039) Peptidase M14, carboxypeptidase A (IPR000834);Proteinase inhibitor, carboxypeptidase propeptide (IPR003146);Proteinase inhibitor, propeptide (IPR009020) high 4.42442683636 209496_at RARRES2 HP10433;RARRES2;TIG2 5919 retinoic acid receptor responder (tazarotene induced) 2 molecular_function unknown (GO:0005554);retinoid metabolism (GO:0001523) Bipartite nuclear localization signal (IPR001472) high 4.42295320656 204412_s_at NEFH KIAA0845;NEFH;NFH 4744 neurofilament, heavy polypeptide 200kDa DNA binding (GO:0003677);molecular_function unknown (GO:0005554);neurogenesis (GO:0007399);nucleosome assembly (GO:0006334);structural molecule activity (GO:0005198) Histone H5 (IPR005819);Intermediate filament protein (IPR001664) high 4.41122406945 214203_s_at PRODH HSPOX2;PIG6;PRODH;PRODH1;PRODH2;TP53I6 5625 proline dehydrogenase (oxidase) 1 glutamate biosynthesis (GO:0006537);proline catabolism (GO:0006562);proline dehydrogenase activity (GO:0004657);proline metabolism (GO:0006560) Proline dehydrogenase (IPR002872) high 4.3926010102 217403_s_at ZNF227 ZNF227 7770 zinc finger protein 227 nucleic acid binding (GO:0003676);zinc ion binding (GO:0008270) KRAB box (IPR001909);Zn-finger, C2H2 type (IPR007087) high 4.38829800152 202936_s_at SOX9 CMD1;CMPD1;SOX9;SRA1 6662 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) DNA binding (GO:0003677);RNA polymerase II transcription factor activity (GO:0003702);skeletal development (GO:0001501);specific RNA polymerase II transcription factor activity (GO:0003704) Bipartite nuclear localization signal (IPR001472);HMG1/2 (high mobility group) box (IPR000910);Proline-rich region (IPR000694) high 4.38650290984 49306_at RASSF4 AD037;MGC44914;RASSF4 83937 Ras association (RalGDS/AF-6) domain family 4 neuropeptide signaling pathway (GO:0007218);protein dimerization activity (GO:0046983);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);RA domain (IPR000159) high 4.38573654033 209670_at Hs.74647 None None CDNA clone MGC:71411 IMAGE:4853814, complete cds MHC protein binding (GO:0042287);immune response (GO:0006955);peptide antigen binding (GO:0042605) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) high 4.37172897855 217147_s_at TRIM HSPC062;TRIM 50852 T-cell receptor interacting molecule DNA binding (GO:0003677);cellular defense response (GO:0006968);signal transduction (GO:0007165);transmembrane receptor protein tyrosine kinase adaptor protein activity (GO:0005068) None high 4.36749026118 209047_at AQP1 AQP-CHIP;AQP1;CHIP28;MGC26324 358 aquaporin 1 (channel-forming integral protein, 28kDa) excretion (GO:0007588);porin activity (GO:0015288);transport (GO:0006810);transporter activity (GO:0005215);water transport (GO:0006833);water transporter activity (GO:0005372) Major intrinsic protein (IPR000425) high 4.36543513025 209933_s_at CMRF-35H CMRF-35-H9;CMRF-35H;CMRF35H;CMRF35H9;IRC1;IRC2;IRp60 11314 leukocyte membrane antigen receptor activity (GO:0004872) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 4.36514696198 209969_s_at STAT1 ISGF-3;STAT1;STAT91 6772 signal transducer and activator of transcription 1, 91kDa DNA binding (GO:0003677);I-kappaB kinase/NF-kappaB cascade (GO:0007249);JAK-STAT cascade (GO:0007259);hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity (GO:0005062);intracellular signaling cascade (GO:0007242);response to pest/pathogen/parasite (GO:0009613);signal transducer activity (GO:0004871);signal transduction (GO:0007165);transcription activating factor (GO:0003710);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182);tyrosine phosphorylation of STAT protein (GO:0007260) SH2 motif (IPR000980);STAT protein (IPR001217);p53-like transcription factor, DNA-binding (IPR008967) high 4.35368078609 205113_at NEF3 NEF3;NEFM;NF-M;NFM 4741 neurofilament 3 (150kDa medium) structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Intermediate filament, DNA-binding region (IPR006821);Keratin, type I (IPR002957) high 4.35112911866 gnf1h08809_at RNF157 KIAA1917;RNF157 114804 ring finger protein 157 None Zn-finger, RING (IPR001841) high 4.34518306395 201761_at MTHFD2 MTHFD2;NMDMC 10797 methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase catalytic activity (GO:0003824);electron transporter activity (GO:0005489);folic acid and derivative biosynthesis (GO:0009396);hydrolase activity (GO:0016787);magnesium ion binding (GO:0000287);methenyltetrahydrofolate cyclohydrolase activity (GO:0004477);methylenetetrahydrofolate dehydrogenase (NAD+) activity (GO:0004487);methylenetetrahydrofolate dehydrogenase activity (GO:0004486);one-carbon compound metabolism (GO:0006730);oxidoreductase activity (GO:0016491) Tetrahydrofolate dehydrogenase/cyclohydrolase (IPR000672) low -3.54240191278 221239_s_at SPAP1 FCRH2;IFGP4;IRTA4;SPAP1;SPAP1A;SPAP1B;SPAP1C 79368 SH2 domain containing phosphatase anchor protein 1 SH3/SH2 adaptor protein activity (GO:0005070);cell-cell signaling (GO:0007267);receptor activity (GO:0004872) Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -3.55639775603 203407_at PPL KIAA0568;PPL 5493 periplakin structural constituent of cytoskeleton (GO:0005200) Bipartite nuclear localization signal (IPR001472) low -3.55864565922 208341_x_at CSH2 CSB;CSH2 1443 chorionic somatomammotropin hormone 2 cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);pregnancy (GO:0007565);signal transduction (GO:0007165) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.57371905168 211756_at PTHLH HHM;MGC14611;PLP;PTHLH;PTHR;PTHRP 5744 parathyroid hormone-like hormone cAMP generating peptide activity (GO:0008492);cAMP metabolism (GO:0046058);cell proliferation (GO:0008283);cell-cell signaling (GO:0007267);excretion (GO:0007588);hormone activity (GO:0005179);lactation (GO:0007595);negative regulation of cell proliferation (GO:0008285);oncogenesis (GO:0007048);peptide hormone (GO:0005180);positive regulation of cell proliferation (GO:0008284);pregnancy (GO:0007565) Bipartite nuclear localization signal (IPR001472);Parathyroid hormone (IPR001415);Parathyroid hormone-related protein (IPR003626) low -3.57429496899 gnf1h10439_s_at gnf1h10439_s_at None None None None None low -3.57708052551 204637_at CGA CG-ALPHA;CGA;FSHA;GPHA1;GPHa;HCG;LHA;TSHA 1081 glycoprotein hormones, alpha polypeptide cell-cell signaling (GO:0007267);hormone activity (GO:0005179);signal transduction (GO:0007165) Glycoprotein hormone alpha chain (IPR000476);Growth factor, cystine knot (IPR002400) low -3.57725299967 220484_at MCOLN3 FLJ11006;MCOLN3 55283 mucolipin 3 cation channel activity (GO:0005261);cation transport (GO:0006812) Cation (not K+) channel, TM region (IPR002111);Ion transport protein (IPR005821) low -3.5914093233 220889_s_at CA10 CA-RPX;CA10;CARPX;HUCEP-15 56934 carbonic anhydrase X carbonate dehydratase activity (GO:0004089);molecular_function unknown (GO:0005554);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) low -3.60540255101 208068_x_at GH1 GH-N;GH1;GHN 2688 growth hormone 1 hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Somatotropin hormone (IPR001400) low -3.60614593939 216604_s_at SLC7A8 LAT2;LPI-PC1;SLC7A8 23428 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 amino acid metabolism (GO:0006520);amino acid permease activity (GO:0015359);amino acid transport (GO:0006865);amino acid-polyamine transporter activity (GO:0005279);neutral amino acid transporter activity (GO:0015175);protein complex assembly (GO:0006461);small molecule transport (GO:0006832);transport (GO:0006810) Amino acid permease-associated region (IPR004841);Amino acid/polyamine transporter I (IPR002293);L-type amino acid transporter (IPR004760) low -3.60779365836 206195_x_at GH2 GH-V;GH2;GHL;GHV 2689 growth hormone 2 hormone activity (GO:0005179);peptide hormone (GO:0005180) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.63230915323 217124_at KIAA1023 KIAA1023 23288 KIAA1023 protein None IQ calmodulin-binding region (IPR000048) low -3.65011021753 204671_s_at ANKRD6 ANKRD6;KIAA0957 22881 ankyrin repeat domain 6 None None low -3.65084727905 gnf1h05065_at gnf1h05065_at None None None None None low -3.65089024025 211032_at COBLL1 COBLL1;KIAA0977 22837 COBL-like 1 None Actin-binding WH2 (IPR003124) low -3.6532097155 216635_at Hs.306310 None None MRNA; cDNA DKFZp566M0524 (from clone DKFZp566M0524) None None low -3.66956834632 208294_x_at CSHL1 CS-5;CSHL1;CSHP1;CSL;hCS-L 1444 chorionic somatomammotropin hormone-like 1 biological_process unknown (GO:0000004);hormone activity (GO:0005179) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.67640948425 gnf1h09336_s_at GNAQ G-ALPHA-q;GNAQ 2776 guanine nucleotide binding protein (G protein), q polypeptide G-protein coupled receptor protein signaling pathway (GO:0007186);GTP binding (GO:0005525);blood coagulation (GO:0007596);heterotrimeric G-protein GTPase activity (GO:0003927);heterotrimeric G-protein GTPase, alpha-subunit (GO:0000263);protein amino acid ADP-ribosylation (GO:0006471);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Fungal G-protein, alpha subunit (IPR002975);G-protein alpha subunit, group Q (IPR000654);Guanine nucleotide binding protein (G-protein), alpha subunit (IPR001019) low -3.68321383989 gnf1h09376_x_at FOXP2 CAGH44;FOXP2;SPCH1;TNRC10 93986 forkhead box P2 neurogenesis (GO:0007399);nucleic acid binding (GO:0003676);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);zinc ion binding (GO:0008270) Fork head transcription factor (IPR001766);Winged helix DNA-binding (IPR009058);Zn-finger, C2H2 type (IPR007087) low -3.69084799381 208357_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.69418936384 209525_at HDGFRP3 CGI-142;HDGF2;HDGFRP3 50810 hepatoma-derived growth factor, related protein 3 cell proliferation (GO:0008283) Bipartite nuclear localization signal (IPR001472);PWWP domain (IPR000313) low -3.71198166617 gnf1h01157_at JM11 JM11 90060 JM11 protein None Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694) low -3.71935550594 209126_x_at KRT6B CK6B;K6B;KRT6B;PC2 3854 keratin 6B cell differentiation (GO:0030154);cytoskeleton organization and biogenesis (GO:0007010);positive regulation of cell proliferation (GO:0008284);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Type II keratin (IPR003054) low -3.72870051569 204534_at VTN V75;VNT;VTN 7448 vitronectin (serum spreading factor, somatomedin B, complement S-protein) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);heparin binding (GO:0008201);immune response (GO:0006955);protein binding (GO:0005515) Hemopexin (IPR000585);Somatomedin B (IPR001212) low -3.73398047387 gnf1h03329_at TMPRSS9 TMPRSS9 360200 transmembrane serine protease 9 proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314) low -3.73696395976 208342_x_at CSH2 CSB;CSH2 1443 chorionic somatomammotropin hormone 2 cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);pregnancy (GO:0007565);signal transduction (GO:0007165) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.74070361469 219970_at GIPC2 FLJ20075;GIPC2;SEMCAP2 54810 PDZ domain protein GIPC2 intracellular signaling cascade (GO:0007242);protein binding (GO:0005515) PDZ/DHR/GLGF domain (IPR001478) low -3.74899929514 215307_at Hs.170079 None None MRNA full length insert cDNA clone EUROIMAGE 31619 None None low -3.7662390926 211382_s_at TACC2 AZU-1;ECTACC;TACC2 10579 transforming, acidic coiled-coil containing protein 2 oncogenesis (GO:0007048) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);Transforming acidic coiled-coil-containing (IPR007707) low -3.76894255142 205767_at EREG EREG 2069 epiregulin cell proliferation (GO:0008283);cell-cell signaling (GO:0007267);epidermal growth factor receptor binding (GO:0005154);epidermal growth factor receptor signaling pathway (GO:0007173);growth factor activity (GO:0008083) EGF-like domain (IPR006209);Type I EGF (IPR006210);Type I EGF subtype (IPR001336) low -3.8016583562 215793_at MTMR7 MTMR7 9108 myotubularin related protein 7 protein amino acid dephosphorylation (GO:0006470);protein tyrosine phosphatase activity (GO:0004725) Cytochrome P450 (IPR001128);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) low -3.80247315676 gnf1h02670_at SYCP3 COR1;SCP3;SYCP3 50511 synaptonemal complex protein 3 None Cor1/Xlr/Xmr conserved region (IPR006888) low -3.82249086788 219825_at CYP26B1 CYP26A2;CYP26B1;P450RAI-2 56603 cytochrome P450, family 26, subfamily B, polypeptide 1 cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);monooxygenase activity (GO:0004497) B-class P450 (IPR002397);Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) low -3.84212742127 219497_s_at BCL11A BCL11A;BCL11A-L;BCL11A-S;BCL11A-XL;CTIP1;EVI9;FLJ10173;KIAA1809 53335 B-cell CLL/lymphoma 11A (zinc finger protein) hemopoiesis (GO:0030097);nucleic acid binding (GO:0003676);zinc ion binding (GO:0008270) Proline-rich region (IPR000694);Zn-finger, C2H2 type (IPR007087) low -3.86389434441 218990_s_at SPRR3 SPRR3 6707 small proline-rich protein 3 structural molecule activity (GO:0005198) Cornifin (SPRR) (IPR003302);Proline-rich region (IPR000694) low -3.86666326785 203399_x_at PSG3 PSG3 5671 pregnancy specific beta-1-glycoprotein 3 defense response (GO:0006952);molecular_function unknown (GO:0005554);pregnancy (GO:0007565) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -3.87333190193 210387_at HIST1H2BG H2B.1A;H2B/a;H2B/g;H2BFA;H2BFG;HIST1H2BF;HIST1H2BG 8339 histone 1, H2bg DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H2B (IPR000558);Histone core (IPR007125);Histone-fold/TFIID-TAF/NF-Y (IPR007124) low -3.88780932144 202178_at PRKCZ PKC2;PRKCZ 5590 protein kinase C, zeta ATP binding (GO:0005524);atypical protein kinase C activity (GO:0004700);cAMP-dependent protein kinase activity (GO:0004691);diacylglycerol binding (GO:0019992);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);signal transduction (GO:0007165);transferase activity (GO:0016740) Octicosapeptide/Phox/Bem1p (IPR000270);Protein kinase (IPR000719);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -3.89666341619 211508_s_at GH2 GH-V;GH2;GHL;GHV 2689 growth hormone 2 hormone activity (GO:0005179);peptide hormone (GO:0005180) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.90329226498 gnf1h04419_s_at KIAA0303 KIAA0303 23227 KIAA0303 protein ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);transferase activity (GO:0016740) PDZ/DHR/GLGF domain (IPR001478);Protein kinase (IPR000719);Protein kinase C-terminal domain (IPR000961);Serine/threonine protein kinase (IPR002290) low -3.90589460097 gnf1h03291_at gnf1h03291_at None None None None None low -3.90993061408 205958_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -3.92542312679 208069_x_at GH1 GH-N;GH1;GHN 2688 growth hormone 1 hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Somatotropin hormone (IPR001400) low -3.9312202611 217617_at Hs.443516 None None Transcribed sequence with weak similarity to protein ref:NP_060312.1 (H.sapiens) hypothetical protein FLJ20489 [Homo sapiens] None None low -3.94391546269 212336_at EPB41L1 4.1N;EPB41L1;KIAA0338;MGC11072 2036 erythrocyte membrane protein band 4.1-like 1 actin binding (GO:0003779);cortical actin cytoskeleton organization and biogenesis (GO:0030866);structural molecule activity (GO:0005198) 4.1, C-terminal (IPR008379);Band 4.1 (IPR000299);Ezrin/radixin/moesin ERM (IPR000798);FERM (IPR009065);SAB (IPR007477) low -3.95578333916 219655_at C7orf10 C7orf10;DERP13;FLJ11808;ORF19 79783 chromosome 7 open reading frame 10 metabolism (GO:0008152) L-carnitine dehydratase/bile acid-inducible protein F (IPR003673) low -3.97424535332 205933_at SETBP1 KIAA0437;SEB;SETBP1 26040 SET binding protein 1 DNA binding (GO:0003677);transport (GO:0006810);transporter activity (GO:0005215) Bipartite nuclear localization signal (IPR001472);HMG-I and HMG-Y DNA-binding domain (A+T-hook) (IPR000637);Proline-rich region (IPR000694) low -3.99232528976 208257_x_at PSG1 B1G1;CD66f;PBG1;PSBG1;PSG1;PSGGA;SP1 5669 pregnancy specific beta-1-glycoprotein 1 plasma glycoprotein (GO:0005211);pregnancy (GO:0007565) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin-like (IPR007110) low -4.00933359921 209994_s_at ABCB1 ABC20;ABCB1;CD243;CLCS;GP170;MDR1;P-gp;PGY1 5243 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ATP binding (GO:0005524);ATP-binding cassette (ABC) transporter activity (GO:0004009);drug resistance (GO:0009315);nucleotide binding (GO:0000166);response to drug (GO:0042493);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215) AAA ATPase (IPR003593);ABC transporter (IPR003439);ABC transporter, transmembrane region (IPR001140);Bipartite nuclear localization signal (IPR001472) low -4.02279837266 213435_at SATB2 FLJ21474;KIAA1034;SATB2 23314 SATB family member 2 DNA binding (GO:0003677);transcription factor activity (GO:0003700) Cut homeobox (IPR007108);Homeobox (IPR001356);Homeodomain protein CUT (IPR003350) low -4.03614978951 gnf1h04567_x_at gnf1h04567_x_at None None None None None low -4.03856332949 203647_s_at FDX1 ADX;FDX;FDX1 2230 ferredoxin 1 adrenodoxin-type ferredoxin (GO:0009493);electron carrier activity (GO:0009055);electron transport (GO:0006118);electron transporter activity (GO:0005489);energy pathways (GO:0006091);iron ion binding (GO:0005506);steroid metabolism (GO:0008202);vitamin metabolism (GO:0006766) Adrenodoxin (IPR001055);Ferredoxin (IPR001041) low -4.06045858229 206033_s_at DSC3 CDHF3;DSC;DSC1;DSC2;DSC3;DSC4;HT-CP 1825 desmocollin 3 calcium ion binding (GO:0005509);calcium-dependent cell adhesion molecule activity (GO:0008014);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515) Cadherin (IPR002126);Cadherin cytoplasmic region (IPR000233);Desmocollin (IPR009124);Desmosomal cadherin (IPR009122) low -4.0923197688 gnf1h04130_x_at gnf1h04130_x_at None None None None None low -4.11471063275 gnf1h04195_at gnf1h04195_at None None None None None low -4.12721618666 217461_x_at 217461_x_at None None None None Bipartite nuclear localization signal (IPR001472);Nascent polypeptide-associated complex NAC (IPR002715) low -4.13394274987 203220_s_at TLE1 ESG;ESG1;GRG1;TLE1 7088 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) development (GO:0007275);frizzled signaling pathway (GO:0007222);histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Groucho/TLE N-terminal Q-rich domain (IPR005617) low -4.13745821641 207285_x_at CSHL1 CS-5;CSHL1;CSHP1;CSL;hCS-L 1444 chorionic somatomammotropin hormone-like 1 biological_process unknown (GO:0000004);hormone activity (GO:0005179) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -4.16504512678 205302_at IGFBP1 IBP1;IGF-BP25;IGFBP1 3484 insulin-like growth factor binding protein 1 cell growth and/or maintenance (GO:0008151);insulin-like growth factor binding (GO:0005520);regulation of cell growth (GO:0001558);signal transduction (GO:0007165) Growth factor, receptor (IPR009030);Insulin-like growth factor binding protein (IPR009168);Insulin-like growth factor-binding protein, IGFBP (IPR000867);Thyroglobulin type-1 (IPR000716) low -4.18992341411 211739_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -4.19026684547 gnf1h04881_at na None 392509 similar to hypothetical protein DKFZp761H079 isoform 1 None None low -4.1912471469 202493_x_at CSH1 CSA;CSH1;CSMT 1442 chorionic somatomammotropin hormone 1 (placental lactogen) cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);peptide hormone (GO:0005180);pregnancy (GO:0007565);signal transduction (GO:0007165);structural constituent of chorion (sensu Insecta) (GO:0005213) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -4.20501564254 218806_s_at VAV3 VAV3 10451 vav 3 oncogene GTPase activator activity (GO:0005096);SH3/SH2 adaptor protein activity (GO:0005070);diacylglycerol binding (GO:0019992);guanyl-nucleotide exchange factor activity (GO:0005085);intracellular signaling cascade (GO:0007242);small GTPase mediated signal transduction (GO:0007264) Aldehyde dehydrogenase (IPR002086);Calponin-like actin-binding (IPR001715);Calponin-like actin-binding subtype (IPR003247);DH domain (IPR000219);Guanine-nucleotide dissociation stimulator, CDC24 (IPR001331);Pleckstrin-like (IPR001849);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);SH2 motif (IPR000980);SH3 (IPR001452);SM22/calponin (IPR003096) low -4.22879096326 212979_s_at 212979_s_at None None None None None low -4.23575056109 209199_s_at MEF2C MEF2C 4208 MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) RNA polymerase II transcription factor activity (GO:0003702);muscle development (GO:0007517);neurogenesis (GO:0007399);transcription (GO:0006350);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) Transcription factor, MADS-box (IPR002100) low -4.26696781921 gnf1h03960_at gnf1h03960_at None None None None None low -4.27018481891 205387_s_at CGB CGB;CGB3 1082 chorionic gonadotropin, beta polypeptide apoptosis (GO:0006915);cell-cell signaling (GO:0007267);female gamete generation (GO:0007292);hormone activity (GO:0005179);signal transduction (GO:0007165) Cystine knot domain (IPR006208);Gonadotropin, beta chain (IPR001545);Growth factor, cystine knot (IPR002400) low -4.31357781596 gnf1h08933_s_at gnf1h08933_s_at None None None None None low -4.3249789553 218435_at DNAJD1 DNAJD1;MCJ 29103 DnaJ (Hsp40) homolog, subfamily D, member 1 None Heat shock protein DnaJ, N-terminal (IPR001623) low -4.32602221145 206885_x_at GH1 GH-N;GH1;GHN 2688 growth hormone 1 hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Somatotropin hormone (IPR001400) low -4.3553448574 220377_at C14orf110 C14orf110;FAM30A;HSPC053 29064 chromosome 14 open reading frame 110 None None low -4.35544616805 gnf1h02751_at gnf1h02751_at None None None None None low -4.39427277872 203710_at ITPR1 IP3R;IP3R1;ITPR1;Insp3r1 3708 inositol 1,4,5-triphosphate receptor, type 1 calcium channel activity (GO:0005262);calcium ion transport (GO:0006816);calcium ion transporter activity (GO:0015085);cation transport (GO:0006812);inositol 1\,4\,5-triphosphate-sensitive calcium-release channel activity (GO:0005220);inositol-1,4,5-triphosphate receptor activity (GO:0008095);signal transduction (GO:0007165);small molecule transport (GO:0006832) Bipartite nuclear localization signal (IPR001472);Ca2+/Na+ channel, pore region (IPR001682);Inositol 1,4,5-trisphosphate-binding protein receptor (IPR000493);Intracellular calcium-release channel (IPR000699);Ion transport protein (IPR005821);MIR domain (IPR003608) low -4.4003228372 208502_s_at PITX1 BFT;PITX1;POTX;PTX1 5307 paired-like homeodomain transcription factor 1 development (GO:0007275);embryogenesis and morphogenesis (GO:0007345);morphogenesis (GO:0009653);skeletal development (GO:0001501);transcription factor activity (GO:0003700);translation regulator activity (GO:0045182) Homeobox (IPR001356);Paired-like homeobox (IPR007104);Paired-like homeodomain protein, OAR (IPR003654) low -4.43489065637 202600_s_at NRIP1 NRIP1;RIP140 8204 nuclear receptor interacting protein 1 receptor activity (GO:0004872);transcription (GO:0006350);transcription coactivator activity (GO:0003713) Bipartite nuclear localization signal (IPR001472) low -4.45923719073 206886_x_at GH1 GH-N;GH1;GHN 2688 growth hormone 1 hormone activity (GO:0005179);peptide hormone (GO:0005180);signal transduction (GO:0007165) Somatotropin hormone (IPR001400) low -4.4693159778 219682_s_at TBX3 TBX3;TBX3-ISO;UMS;XHL 6926 T-box 3 (ulnar mammary syndrome) RNA polymerase II transcription factor activity (GO:0003702);morphogenesis (GO:0009653);skeletal development (GO:0001501);transcription factor activity (GO:0003700) Transcription factor, Brachyury (IPR002070);Transcription factor, T-box (IPR001699);p53-like transcription factor, DNA-binding (IPR008967) low -4.51050578367 205709_s_at CDS1 CDS;CDS1 1040 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 diacylglycerol cholinephosphotransferase activity (GO:0004142);lipid metabolism (GO:0006629);magnesium ion binding (GO:0000287);phosphatidate cytidylyltransferase activity (GO:0004605);phospholipid biosynthesis (GO:0008654);signal transduction (GO:0007165);transferase activity (GO:0016740);visual perception (GO:0007601) Phosphatidate cytidylyltransferase (IPR000374) low -4.53880765535 213139_at SNAI2 MGC10182;SLUG;SLUGH1;SNAI2 6591 snail homolog 2 (Drosophila) DNA binding (GO:0003677);development (GO:0007275);transcription activating factor (GO:0003710);zinc ion binding (GO:0008270) Zn-finger, C2H2 type (IPR007087) low -4.55346545258 214580_x_at KRT6A CK6A;CK6C;K6A;K6C;KRT6A;KRT6C 3853 keratin 6A cytoskeleton organization and biogenesis (GO:0007010);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Type II keratin (IPR003054) low -4.58910670493 213094_at GPR126 DKFZp564D0462;FLJ14937;GPR126;VIGR 57211 G protein-coupled receptor 126 G-protein coupled receptor activity (GO:0004930);neuropeptide signaling pathway (GO:0007218);receptor activity (GO:0004872) CUB (IPR000859);Concanavalin A-like lectin/glucanase (IPR008985);G-protein coupled receptor family 2 (secretin-like) (IPR000832);GPS domain (IPR000203) low -4.64881401015 219073_s_at OSBPL10 FLJ20363;ORP10;OSBP9;OSBPL10 114884 oxysterol binding protein-like 10 lipid transport (GO:0006869);steroid metabolism (GO:0008202) Bipartite nuclear localization signal (IPR001472);Oxysterol-binding protein (IPR000648);Pleckstrin-like (IPR001849) low -4.6756911292 203646_at FDX1 ADX;FDX;FDX1 2230 ferredoxin 1 adrenodoxin-type ferredoxin (GO:0009493);electron carrier activity (GO:0009055);electron transport (GO:0006118);electron transporter activity (GO:0005489);energy pathways (GO:0006091);iron ion binding (GO:0005506);steroid metabolism (GO:0008202);vitamin metabolism (GO:0006766) Adrenodoxin (IPR001055);Ferredoxin (IPR001041) low -4.68204299288 203680_at PRKAR2B PRKAR2;PRKAR2B;RII-BETA 5577 protein kinase, cAMP-dependent, regulatory, type II, beta cAMP-dependent protein kinase regulator activity (GO:0008603);intracellular signaling cascade (GO:0007242) Cyclic nucleotide-binding domain (IPR000595);cAMP-dependent protein kinase (IPR002373);cAMP-dependent protein kinase regulator, type II PKA R subunit (IPR003117) low -4.71693821172 217809_at BZW2 BZW2;HSPC028 28969 basic leucine zipper and W2 domains 2 translation initiation factor activity (GO:0003743) eIF4-gamma/eIF5/eIF2-epsilon (IPR003307) low -4.7370170029 203807_x_at CSH2 CSB;CSH2 1443 chorionic somatomammotropin hormone 2 cell-cell signaling (GO:0007267);growth hormone receptor binding (GO:0005131);hormone activity (GO:0005179);pregnancy (GO:0007565);signal transduction (GO:0007165) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -4.78863081046 219523_s_at ODZ3 FLJ10474;FLJ10886;ODZ3;Ten-m3 55714 odd Oz/Ten-m homolog 3 None Carboxypeptidase regulatory domain (IPR008969);Teneurin intracellular, N-terminal (IPR009471) low -4.80624555524 gnf1h04131_x_at gnf1h04131_x_at None None None None None low -4.82109781963 204309_at CYP11A1 CYP11A;CYP11A1;P450SCC 1583 cytochrome P450, family 11, subfamily A, polypeptide 1 C21-steroid hormone biosynthesis (GO:0006700);androgen biosynthesis (GO:0006702);cholesterol metabolism (GO:0008203);cholesterol monooxygenase (side-chain-cleaving) activity (GO:0008386);cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);electron transporter activity (GO:0005489);monooxygenase activity (GO:0004497);oxygen binding (GO:0019825);steroid biosynthesis (GO:0006694) B-class P450 (IPR002397);Cytochrome P450 (IPR001128);E-class P450, group I (IPR002401);E-class P450, group IV (IPR002403) low -4.85039539637 215321_at RPIB9 FLJ30671;MGC26655;RPIB9;RPIP9 154661 Rap2-binding protein 9 None RUN domain (IPR004012) low -4.89820774106 208134_x_at PSG2 PSBG2;PSG2;PSGGB 5670 pregnancy specific beta-1-glycoprotein 2 cell migration (GO:0016477);molecular_function unknown (GO:0005554);pregnancy (GO:0007565) Immunoglobulin C-2 type (IPR003598);Immunoglobulin-like (IPR007110) low -5.00356853033 206023_at NMU NMU 10874 neuromedin U G-protein coupled receptor protein signaling pathway (GO:0007186);digestion (GO:0007586);neuropeptide signaling pathway (GO:0007218);receptor binding (GO:0005102);signal transduction (GO:0007165) Neuromedin U (IPR008199);Neuromedin U, C-terminal (IPR008200) low -5.1066277795 201983_s_at EGFR EGFR;ERBB;ERBB1 1956 epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) ATP binding (GO:0005524);cell proliferation (GO:0008283);electron transport (GO:0006118);electron transporter activity (GO:0005489);epidermal growth factor receptor activity (GO:0005006);epidermal growth factor receptor signaling pathway (GO:0007173);iron ion binding (GO:0005506);protein amino acid phosphorylation (GO:0006468);receptor activity (GO:0004872);transferase activity (GO:0016740) Epidermal growth-factor receptor (EGFR), L domain (IPR000494);Furin-like cysteine rich region (IPR006211);Growth factor, receptor (IPR009030);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -5.18597785522 202984_s_at BAG5 BAG-5;BAG5;KIAA0873 9529 BCL2-associated athanogene 5 apoptosis (GO:0006915);apoptosis regulator activity (GO:0016329);chaperone activity (GO:0003754);protein binding (GO:0005515);protein folding (GO:0006457) Apoptosis regulator Bcl-2 protein, BAG (IPR003103) low -5.27497493067 219995_s_at FLJ13841 FLJ13841 79755 hypothetical protein FLJ13841 nucleic acid binding (GO:0003676);zinc ion binding (GO:0008270) Bipartite nuclear localization signal (IPR001472);Zn-finger, C2H2 type (IPR007087) low -5.39835326493 206294_at HSD3B2 HSD3B2;HSDB;HSDB3 3284 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);C21-steroid hormone biosynthesis (GO:0006700);isomerase activity (GO:0016853);oxidoreductase activity (GO:0016491);steroid biosynthesis (GO:0006694);steroid delta-isomerase activity (GO:0004769) 3-beta hydroxysteroid dehydrogenase/isomerase (IPR002225) low -5.4423532364 211597_s_at HOP Cameo;HOP;LAGY;MGC20820;NECC1;OB1;SMAP31;Toto 84525 homeodomain-only protein DNA binding (GO:0003677);transcription factor activity (GO:0003700) Homeobox (IPR001356);Homeodomain-like (IPR009057) low -5.44835233374 208295_x_at CSHL1 CS-5;CSHL1;CSHP1;CSL;hCS-L 1444 chorionic somatomammotropin hormone-like 1 biological_process unknown (GO:0000004);hormone activity (GO:0005179) Four-helical cytokine (IPR009079);Somatotropin hormone (IPR001400) low -5.66755379002 204830_x_at PSG4 FL-NCA-3;PSG4;PSG5;PSG9 5672 pregnancy specific beta-1-glycoprotein 4 plasma glycoprotein (GO:0005211);pregnancy (GO:0007565) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110) low -5.69690235261 gnf1h04566_at gnf1h04566_at None None None None None low -5.98807781627 202479_s_at TRIB2 GS3955;TRB2;TRIB2 28951 tribbles homolog 2 (Drosophila) ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);transferase activity (GO:0016740) Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -6.39618138153 209125_at KRT6E KRT6E 286887 keratin 6E cytoskeleton organization and biogenesis (GO:0007010);phosphorylation (GO:0016310);structural molecule activity (GO:0005198) Intermediate filament protein (IPR001664);Type II keratin (IPR003054) low -6.69151393265 gnf1h05066_x_at gnf1h05066_x_at None None None None None low -7.14126340387 209560_s_at DLK1 DLK1;FA1;PREF1;Pref-1;ZOG;pG2 8788 delta-like 1 homolog (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);development (GO:0007275);molecular_function unknown (GO:0005554);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210);Type II EGF-like signature (IPR001438)