PC-2 10 High/Low PC-2 Value ProbeId Name Aliases Description Function Protein Families high 36.3193227358 208791_at CLU APOJ;CLI;CLU;MGC24903;SGP-2;SGP2;SP-40;TRPM-2;TRPM2 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) apoptosis (GO:0006915);cell death (GO:0008219);fertilization (sensu Animalia) (GO:0007338);lipid metabolism (GO:0006629);plasma glycoprotein (GO:0005211) Bipartite nuclear localization signal (IPR001472);Clusterin (IPR000753) high 33.4946924947 209072_at MBP MBP myelin basic protein DNA binding (GO:0003677);immune response (GO:0006955);structural constituent of myelin sheath (GO:0019911);structural molecule activity (GO:0005198) Myelin basic protein (IPR000548) high 31.244244289 203382_s_at APOE APOE apolipoprotein E antioxidant activity (GO:0016209);apolipoprotein E receptor binding (GO:0050749);beta-amyloid binding (GO:0001540);cholesterol homeostasis (GO:0042632);cholesterol metabolism (GO:0008203);circulation (GO:0008015);cytoskeleton organization and biogenesis (GO:0007010);development (GO:0007275);heparin binding (GO:0008201);immune response (GO:0006955);intracellular transport (GO:0046907);learning and/or memory (GO:0007611);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);low-density lipoprotein receptor binding (GO:0050750);plasma protein (GO:0005209);receptor binding (GO:0005102);response to reactive oxygen species (GO:0000302);tau protein binding (GO:0048156) Apolipoprotein A1/A4/E (IPR000074) high 31.05758958 200795_at SPARCL1 HEVIN;MAST9;SC1;SPARCL1 SPARC-like 1 (mast9, hevin) calcium ion binding (GO:0005509) Calcium-binding EF-hand (IPR002048);Follistatin-like, N-terminal (IPR003645);Osteonectin-like (IPR001999);Proteinase inhibitor I1, Kazal (IPR002350) high 30.1257097702 210198_s_at PLP1 MMPL;PLP;PLP/DM20;PLP1;PMD;SPG2 proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) structural molecule activity (GO:0005198) Myelin proteolipid protein PLP (IPR001614) high 30.0095274613 212233_at MAP1B FUTSCH;MAP1B;MAP5 microtubule-associated protein 1B microtubule-based process (GO:0007017);structural molecule activity (GO:0005198) Bipartite nuclear localization signal (IPR001472) high 29.5471611125 217414_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 29.3024800979 201427_s_at SEPP1 SEPP1;SeP selenoprotein P, plasma, 1 response to oxidative stress (GO:0006979);selenium binding (GO:0008430) Selenoprotein P, C-terminal (IPR007672);Selenoprotein P, N-terminal (IPR007671) high 28.8419386677 202508_s_at SNAP25 FLJ23079;SNAP;SNAP-25;SNAP25;bA416N4.2;dJ1068F16.2 synaptosomal-associated protein, 25kDa molecular_function unknown (GO:0005554);neurotransmitter secretion (GO:0007269);regulation of synapse (GO:0007273) SNAP-25 (IPR000928);Target SNARE coiled-coil domain (IPR000727) high 28.8112192557 201525_at APOD APOD apolipoprotein D high-density lipoprotein (GO:0005321);high-density lipoprotein binding (GO:0008035);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transporter activity (GO:0005319);transport (GO:0006810);transporter activity (GO:0005215) Apolipoprotein D (IPR002969);Bacterial lipocalin (IPR002446);Invertebrate colouration protein (IPR003057);Lipocalin (IPR002345);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566);Retinol-binding protein (IPR002449) low -21.5690095578 209083_at CORO1A CLABP;CLIPINA;CORO1A;Clabp TACO;HAST;HAST3;HCORO1;M-PST;STM;SULT1A3;TACO;TL-PST;p57 coronin, actin binding protein, 1A DNA repair (GO:0006281);actin binding (GO:0003779);amine biosynthesis (GO:0009309);amine metabolism (GO:0009308);aryl sulfotransferase activity (GO:0004062);catecholamine metabolism (GO:0006584);cell motility (GO:0006928);nuclease activity (GO:0004518);phagosome formation (GO:0006912);steroid metabolism (GO:0008202);structural molecule activity (GO:0005198);sulfotransferase activity (GO:0008146);transferase activity (GO:0016740);transport (GO:0006810) Excinuclease ABC, C subunit, N-terminal (IPR000305);Sulfotransferase (IPR000863) low -22.44400857 201288_at ARHGDIB ARHGDIB;GDIA2;GDID4;LYGDI;RAP1GN1 Rho GDP dissociation inhibitor (GDI) beta GTPase activator activity (GO:0005096);Rho GDP-dissociation inhibitor activity (GO:0005094);Rho protein signal transduction (GO:0007266);actin cytoskeleton organization and biogenesis (GO:0030036);actin cytoskeleton reorganization (GO:0007012);development (GO:0007275);immune response (GO:0006955);negative regulation of cell adhesion (GO:0007162) Immunoglobulin-like (IPR007110);RHO protein GDP dissociation inhibitor (IPR000406) low -22.5643000351 213160_at DOCK2 DOCK2;KIAA0209 dedicator of cytokinesis 2 GTPase activator activity (GO:0005096);Rac guanyl-nucleotide exchange factor activity (GO:0030676);T-cell receptor binding (GO:0042608);actin cytoskeleton organization and biogenesis (GO:0030036);lymphocyte chemotaxis (GO:0048247);small GTPase mediated signal transduction (GO:0007264) SH3 (IPR001452) low -22.7434530932 216237_s_at MCM5 CDC46;MCM5;MGC5315;P1-CDC46 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) ATP binding (GO:0005524);DNA binding (GO:0003677);DNA replication (GO:0006260);DNA-dependent ATPase activity (GO:0008094);cell cycle regulator (GO:0003750) Bipartite nuclear localization signal (IPR001472);MCM (IPR001208);MCM protein 5 (IPR008048) low -22.9544420529 209040_s_at PSMB8 D6S216;D6S216E;LMP7;MGC1491;PSMB8;RING10 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) endopeptidase activity (GO:0004175);immune response (GO:0006955);peptidase activity (GO:0008233);proteasome endopeptidase activity (GO:0004299);proteolysis and peptidolysis (GO:0006508);ubiquitin-dependent protein catabolism (GO:0006511) 20S proteasome, A and B subunits (IPR001353);Peptidase T1A, proteasome beta-subunit (IPR000243) low -22.996785727 212873_at HA-1 HA-1;HLA-HA1;KIAA0223 minor histocompatibility antigen HA-1 intracellular signaling cascade (GO:0007242) Bipartite nuclear localization signal (IPR001472);Cdc15/Fes/CIP4 (IPR001060);Protein kinase C, phorbol ester/diacylglycerol binding (IPR002219);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198) low -23.7923180278 207419_s_at RAC2 EN-7;HSPC022;RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) GTP binding (GO:0005525);GTPase activity (GO:0003924);Rho small monomeric GTPase activity (GO:0003931);signal transduction (GO:0007165);small GTPase mediated signal transduction (GO:0007264) Ras GTPase superfamily (IPR001806);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -24.3697952913 204661_at CDW52 CD52;CDW52 CDW52 antigen (CAMPATH-1 antigen) lymphocyte antigen (GO:0005557) None low -25.3229596592 34210_at CDW52 CD52;CDW52 CDW52 antigen (CAMPATH-1 antigen) lymphocyte antigen (GO:0005557) None low -25.4950916362 208998_at UCP2 SLC25A8;UCP2;UCPH uncoupling protein 2 (mitochondrial, proton carrier) binding (GO:0005488);mitochondrial transport (GO:0006839);proton transport (GO:0015992);small molecule transport (GO:0006832);transport (GO:0006810);transporter activity (GO:0005215);uncoupling protein activity (GO:0015302) Adenine nucleotide translocator 1 (IPR002113);Mitochondrial brown fat uncoupling protein (IPR002030);Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993)