PC-12 10 High/Low PC-12 Value ProbeId Name Aliases Description Function Protein Families high 9.25584258524 204570_at COX7A1 COX7A;COX7A1;COX7AH;COX7AM cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) aa3-type cytochrome c oxidase (GO:0009481);ba3-type cytochrome c oxidase (GO:0009482);caa3-type cytochrome c oxidase (GO:0009483);cbb3-type cytochrome c oxidase (GO:0009485);cytochrome-c oxidase activity (GO:0004129);electron transport (GO:0006118);electron transporter activity (GO:0005489);energy pathways (GO:0006091);oxidoreductase activity (GO:0016491) Cytochrome c oxidase, subunit VIIa (IPR003177) high 9.12165060321 217757_at A2M A2M alpha-2-macroglobulin alpha-2 macroglobulin (GO:0016975);endopeptidase inhibitor activity (GO:0004866);enzyme binding (GO:0019899);intracellular protein transport (GO:0006886);protein carrier activity (GO:0008320);protein homooligomerization activity (GO:0042804);serine-type endopeptidase inhibitor activity (GO:0004867);wide-spectrum protease inhibitor activity (GO:0017114) Alpha-2-macroglobulin (IPR001599);Alpha-2-macroglobulin, N-terminal (IPR002890);Alpha-macroglobulin, receptor-binding (IPR009048);Terpenoid cylases/protein prenyltransferase alpha-alpha toroid (IPR008930);TonB-dependent receptor (IPR000531) high 8.87202227305 201427_s_at SEPP1 SEPP1;SeP selenoprotein P, plasma, 1 response to oxidative stress (GO:0006979);selenium binding (GO:0008430) Selenoprotein P, C-terminal (IPR007672);Selenoprotein P, N-terminal (IPR007671) high 8.79086668458 206093_x_at TNXB HXBL;TENX;TNX;TNXB;TNXB1;TNXB2;TNXBS;XBS tenascin XB cell adhesion (GO:0007155);cell-matrix adhesion (GO:0007160);extracellular matrix structural constituent (GO:0005201);protein binding (GO:0005515) Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210) high 8.49335946488 204737_s_at MYH7 CMH1;MYH7;MYHCB myosin, heavy polypeptide 7, cardiac muscle, beta ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);microfilament motor activity (GO:0000146);motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928);Tropomyosin (IPR000533) high 8.41816856131 216333_x_at TNXB HXBL;TENX;TNX;TNXB;TNXB1;TNXB2;TNXBS;XBS tenascin XB cell adhesion (GO:0007155);cell-matrix adhesion (GO:0007160);extracellular matrix structural constituent (GO:0005201);protein binding (GO:0005515) Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210) high 8.26819663752 201744_s_at LUM LDC;LUM;SLRR2D lumican collagen binding (GO:0005518);collagen fibril organization (GO:0030199);extracellular matrix glycoprotein (GO:0005207);extracellular matrix structural constituent (GO:0005201);proteoglycan (GO:0005203);visual perception (GO:0007601) Cysteine-rich flanking region, N-terminal (IPR000372) high 8.1608660611 213451_x_at TNXB HXBL;TENX;TNX;TNXB;TNXB1;TNXB2;TNXBS;XBS tenascin XB cell adhesion (GO:0007155);cell-matrix adhesion (GO:0007160);extracellular matrix structural constituent (GO:0005201);protein binding (GO:0005515) Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210) high 8.12948395975 202291_s_at MGP MGLAP;MGP;NTI matrix Gla protein calcium ion binding (GO:0005509);extracellular matrix structural constituent (GO:0005201);oncogenesis (GO:0007048);perception of sound (GO:0007605);structural constituent of bone (GO:0008147) Bone matrix, Gla region (IPR002384);Vitamin K-dependent carboxylation/gamma-carboxyglutamic region (IPR000294) high 8.00512597759 205353_s_at PBP PBP;RKIP prostatic binding protein ATP binding (GO:0005524);lipid binding (GO:0008289);phosphatidylethanolamine binding (GO:0008429);serine-type endopeptidase inhibitor activity (GO:0004867) PEBP (IPR008914);Phosphatidylethanolamine-binding protein (IPR001858) low -6.52493945265 202497_x_at SLC2A3 GLUT3;SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 carbohydrate metabolism (GO:0005975);carbohydrate transport (GO:0008643);glucose transport (GO:0015758);glucose transporter activity (GO:0005355);sugar porter activity (GO:0005351);transporter activity (GO:0005215) General substrate transporter (IPR005828);Glucose transporter GLUT3, type 3 (IPR002945);Major facilitator superfamily (IPR007114);Sugar transporter (IPR003663);Sugar transporter superfamily (IPR005829) low -6.54119124039 202855_s_at SLC16A3 MCT3;MCT4;SLC16A3 solute carrier family 16 (monocarboxylic acid transporters), member 3 monocarboxylate porter activity (GO:0015355);monocarboxylic acid transport (GO:0015718);monocarboxylic acid transporter activity (GO:0008028);symport (GO:0015983);symporter activity (GO:0015293);transport (GO:0006810);transporter activity (GO:0005215) Major facilitator superfamily (IPR007114);Monocarboxylate transporter (IPR004743) low -6.57722551365 214121_x_at PDLIM7 PDLIM7 PDZ and LIM domain 7 (enigma) protein binding (GO:0005515);receptor mediated endocytosis (GO:0006898) PDZ/DHR/GLGF domain (IPR001478);Zn-binding protein, LIM (IPR001781) low -6.62405373912 205220_at GPR109B GPR109B;HM74;PUMAG;Puma-g G protein-coupled receptor 109B G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);purinergic nucleotide receptor activity\, G-protein coupled (GO:0045028);rhodopsin-like receptor activity (GO:0001584) Rhodopsin-like GPCR superfamily (IPR000276) low -6.62899548285 202859_x_at IL8 3-10C;AMCF-I;CXCL8;GCP-1;GCP1;IL-8;IL8;K60;LECT;LUCT;LYNAP;MDNCF;MONAP;NAF;NAP-1;NAP1;SCYB8;TSG-1;b-ENAP interleukin 8 G-protein coupled receptor protein signaling pathway (GO:0007186);calcium-mediated signaling (GO:0019722);cell adhesion (GO:0007155);cell motility (GO:0006928);cell-cell signaling (GO:0007267);chemokine activity (GO:0008009);chemotaxis (GO:0006935);immune response (GO:0006955);inflammatory response (GO:0006954);interleukin-8 receptor binding (GO:0005153);intracellular signaling cascade (GO:0007242);negative regulation of cell proliferation (GO:0008285);neutrophil activation (GO:0042119);neutrophil chemotaxis (GO:0030593);regulation of cell adhesion (GO:0030155);regulation of retroviral genome replication (GO:0045091);signal transduction (GO:0007165) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) low -6.66206439468 205715_at BST1 BST1;CD157 bone marrow stromal cell antigen 1 GPI-anchored membrane-bound receptor (GO:0015025);NAD+ nucleosidase activity (GO:0003953);development (GO:0007275);humoral immune response (GO:0006959);hydrolase activity (GO:0016787) ADP-ribosyl cyclase (CD38/157) (IPR003193) low -6.99368011126 210873_x_at APOBEC3A APOBEC3A;ARP3;PHRBN;phorbolin I apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A biological_process unknown (GO:0000004);hydrolase activity (GO:0016787);hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);mRNA processing (GO:0006397);molecular_function unknown (GO:0005554);zinc ion binding (GO:0008270) APOBEC-like, C-terminal (IPR007904);Cytidine/deoxycytidylate deaminase, zinc-binding region (IPR002125) low -7.28733447319 204961_s_at NCF1 NCF1;NOXO2;p47phox neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) GTP binding (GO:0005525);GTPase activity (GO:0003924);cellular defense response (GO:0006968);electron transport (GO:0006118);electron transporter activity (GO:0005489);intracellular signaling cascade (GO:0007242);oxygen and reactive oxygen species metabolism (GO:0006800);protein binding (GO:0005515);superoxide metabolism (GO:0006801) Neutrophil cytosol factor 1 (IPR001655);Phox-like (IPR001683);SH3 (IPR001452) low -8.03833135235 208893_s_at DUSP6 DUSP6;MKP3;PYST1 dual specificity phosphatase 6 CTD phosphatase activity (GO:0008420);MAP kinase phosphatase activity (GO:0017017);MAPKKK cascade (GO:0000165);apoptosis (GO:0006915);calcium-dependent protein serine/threonine phosphatase activity (GO:0004723);hydrolase activity (GO:0016787);magnesium-dependent protein serine/threonine phosphatase activity (GO:0004724);myosin phosphatase activity (GO:0017018);phosphoprotein phosphatase activity (GO:0004721);protein amino acid dephosphorylation (GO:0006470);protein phosphatase type 2A activity (GO:0000158);protein phosphatase type 2B activity (GO:0030357);protein phosphatase type 2C activity (GO:0015071);protein serine/threonine phosphatase activity (GO:0004722);protein tyrosine phosphatase activity (GO:0004725);protein tyrosine/serine/threonine phosphatase activity (GO:0008138) Dual specificity protein phosphatase (IPR000340);MAP kinase phosphatase (IPR008343);Rhodanese-like (IPR001763);Tyrosine specific protein phosphatase and dual specificity protein phosphatase (IPR000387) low -8.2587958293 210773_s_at FPRL1 ALXR;FMLP-R-II;FMLPX;FPR2A;FPRH1;FPRH2;FPRL1;HM63;LXA4R formyl peptide receptor-like 1 G-protein coupled receptor activity (GO:0004930);G-protein coupled receptor protein signaling pathway (GO:0007186);N-formyl peptide receptor activity (GO:0004982);cell adhesion (GO:0007155);cell motility (GO:0006928);chemotaxis (GO:0006935);inflammatory response (GO:0006954);rhodopsin-like receptor activity (GO:0001584) Anaphylatoxin chemotactic receptor (IPR002234);Bradykinin receptor (IPR000496);DEZ orphan receptor (IPR002258);Formyl/methionyl peptide receptor (IPR000826);Rhodopsin-like GPCR superfamily (IPR000276)