PC-19 10 High/Low PC-19 Value ProbeId Name Aliases Description Function Protein Families high 8.99283259126 209351_at KRT14 CK14;EBS3;EBS4;K14;KRT14 keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) biological_process unknown (GO:0000004);structural constituent of cytoskeleton (GO:0005200);structural constituent of epidermis (GO:0030280) 14-3-3 protein (IPR000308);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Tachykinin/Neurokinin (IPR002040) high 6.83822087762 209309_at AZGP1 AZGP1;ZA2G;ZAG alpha-2-glycoprotein 1, zinc cell adhesion (GO:0007155);fatty acid binding (GO:0005504);immune response (GO:0006955);lipid catabolism (GO:0016042);negative regulation of cell proliferation (GO:0008285);plasma glycoprotein (GO:0005211);protein carrier activity (GO:0008320);ribonuclease activity (GO:0004540) Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Major histocompatibility complex protein, class I (IPR001039) high 6.57027501675 204734_at KRT15 CK15;K15;K1CO;KRT15 keratin 15 structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Keratin, type I (IPR002957) high 6.4176095945 200872_at S100A10 42C;ANX2L;ANX2LG;CAL1L;CLP11;Ca[1];GP11;P11;S100A10;p10 S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) calcium ion binding (GO:0005509);receptor binding (GO:0005102);signal transduction (GO:0007165) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 6.19716755551 209301_at CA2 CA-II;CA2 carbonic anhydrase II carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) high 6.02917309791 214063_s_at TF PRO1557;PRO2086 transferrin ferric iron binding (GO:0008199);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);transport (GO:0006810) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) high 6.02276938315 204379_s_at FGFR3 ACH;CEK2;FGFR3;HSFGFR3EX;JTK4 fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) ATP binding (GO:0005524);JAK-STAT cascade (GO:0007259);MAPKKK cascade (GO:0000165);cell growth (GO:0016049);fibroblast growth factor receptor activity (GO:0005007);fibroblast growth factor receptor signaling pathway (GO:0008543);oncogenesis (GO:0007048);protein amino acid phosphorylation (GO:0006468);protein-tyrosine kinase activity (GO:0004713);receptor activity (GO:0004872);skeletal development (GO:0001501);transferase activity (GO:0016740) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 5.92751321725 205113_at NEF3 NEF3;NEFM;NF-M;NFM neurofilament 3 (150kDa medium) structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Intermediate filament, DNA-binding region (IPR006821);Keratin, type I (IPR002957) high 5.87210186617 216620_s_at ARHGEF10 ARHGEF10;GEF10;KIAA0294 Rho guanine nucleotide exchange factor (GEF) 10 None DH domain (IPR000219);Peptidase, eukaryotic cysteine peptidase active site (IPR000169) high 5.80798016722 209894_at LEPR LEPR;OBR;OBRGRP leptin receptor biological_process unknown (GO:0000004);cell surface receptor linked signal transduction (GO:0007166);development (GO:0007275);energy reserve metabolism (GO:0006112);hematopoietin/interferon-class (D200-domain) cytokine receptor activity (GO:0004896);molecular_function unknown (GO:0005554);transmembrane receptor activity (GO:0004888) Bipartite nuclear localization signal (IPR001472);Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Immunoglobulin-like (IPR007110);Long hematopoietin receptor, gp130 family 2 (IPR003529);Short hematopoietin receptor, family 1 (IPR003531);Vacuolar protein sorting 55 (IPR007262) low -6.33517839047 204068_at STK3 KRS1;MST2;STK3 serine/threonine kinase 3 (STE20 homolog, yeast) ATP binding (GO:0005524);apoptosis (GO:0006915);cAMP-dependent protein kinase activity (GO:0004691);protein amino acid phosphorylation (GO:0006468);protein kinase CK2 activity (GO:0004682);protein kinase activity (GO:0004672);protein serine/threonine kinase activity (GO:0004674);signal transduction (GO:0007165);transferase activity (GO:0016740) Bipartite nuclear localization signal (IPR001472);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -6.42388995177 209560_s_at DLK1 DLK1;FA1;PREF1;Pref-1;ZOG;pG2 delta-like 1 homolog (Drosophila) biological_process unknown (GO:0000004);calcium ion binding (GO:0005509);development (GO:0007275);molecular_function unknown (GO:0005554);structural molecule activity (GO:0005198) Concanavalin A-like lectin/glucanase (IPR008985);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Laminin-type EGF-like domain (IPR002049);Type I EGF (IPR006210);Type II EGF-like signature (IPR001438) low -6.53640734467 211959_at IGFBP5 IBP5;IGFBP5 insulin-like growth factor binding protein 5 cell growth and/or maintenance (GO:0008151);insulin-like growth factor binding (GO:0005520);regulation of cell growth (GO:0001558);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Growth factor, receptor (IPR009030);Insulin-like growth factor-binding protein, IGFBP (IPR000867);Thyroglobulin type-1 (IPR000716) low -6.54128912563 213714_at CACNB2 CACNB2;CACNLB2;MYSB calcium channel, voltage-dependent, beta 2 subunit calcium ion transport (GO:0006816);ion transport (GO:0006811);small molecule transport (GO:0006832);transport (GO:0006810);voltage-gated calcium channel activity (GO:0005245) Dihydropyridine sensitive L-type calcium channel, beta subunit (IPR000584);Guanylate kinase/L-type calcium channel region (IPR008145);L-type calcium channel beta 2 subunit (IPR005444);SH3 (IPR001452) low -6.55809493339 212095_s_at MTUS1 ATIP1;DKFZp586D1519;FLJ14295;KIAA1288;MP44;MTSG1;MTUS1 mitochondrial tumor suppressor 1 receptor activity (GO:0004872) None low -6.58250859482 219424_at EBI3 EBI3 Epstein-Barr virus induced gene 3 cellular defense response (GO:0006968);hematopoietin/interferon-class (D200-domain) cytokine receptor activity (GO:0004896);humoral immune response (GO:0006959);receptor activity (GO:0004872) Cytokine receptor, common beta/gamma chain (IPR002996);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Long hematopoietin receptor, soluble alpha chain (IPR003530) low -6.85926939872 gnf1h06525_at H19 ASM;ASM1;D11S813E;H19;MGC4485 H19, imprinted maternally expressed untranslated mRNA None None low -7.12639316113 209243_s_at PEG3 KIAA0287;PEG3;PW1;ZIM2 paternally expressed 3 DNA binding (GO:0003677);signal transducer activity (GO:0004871);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) KRAB box (IPR001909);Transcriptional regulator SCAN (IPR003309);Zn-finger, C2H2 type (IPR007087) low -7.89503801414 201744_s_at LUM LDC;LUM;SLRR2D lumican collagen binding (GO:0005518);collagen fibril organization (GO:0030199);extracellular matrix glycoprotein (GO:0005207);extracellular matrix structural constituent (GO:0005201);proteoglycan (GO:0005203);visual perception (GO:0007601) Cysteine-rich flanking region, N-terminal (IPR000372) low -10.1652303418 213792_s_at INSR INSR insulin receptor ATP binding (GO:0005524);carbohydrate metabolism (GO:0005975);cell growth and/or maintenance (GO:0008151);development (GO:0007275);energy pathways (GO:0006091);epidermal growth factor receptor activity (GO:0005006);protein amino acid phosphorylation (GO:0006468);protein serine/threonine kinase activity (GO:0004674);receptor activity (GO:0004872);receptor signaling protein tyrosine kinase activity (GO:0004716);signal transducer activity (GO:0004871);signal transduction (GO:0007165);transferase activity (GO:0016740);transmembrane receptor protein tyrosine kinase activity (GO:0004714);transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);transmembrane receptor protein tyrosine kinase signaling protein activity (GO:0005066) Epidermal growth-factor receptor (EGFR), L domain (IPR000494);Fibronectin, type III (IPR003961);Furin-like cysteine rich region (IPR006211);Growth factor, receptor (IPR009030);Protein kinase (IPR000719);Receptor tyrosine kinase, class II (IPR002011);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245)