PC-21 10 High/Low PC-21 Value ProbeId Name Aliases Description Function Protein Families high 9.81574412491 205910_s_at CEL BAL;BSDL;BSSL;CEL;CELL;CEase;FAP;FAPP;LIPA carboxyl ester lipase (bile salt-stimulated lipase) catalytic activity (GO:0003824);cell differentiation (GO:0030154);cell growth (GO:0016049);cholesterol catabolism (GO:0006707);fat-soluble vitamin catabolism (GO:0042363);hydrolase activity (GO:0016787);lipase activity (GO:0016298);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);protein binding (GO:0005515);serine esterase activity (GO:0004759);sterol esterase activity (GO:0004771) Carboxylesterase, type B (IPR002018);Cholinesterase (IPR000997);Esterase/lipase/thioesterase (IPR000379);Proline-rich region (IPR000694) high 8.22432198867 206598_at INS INS insulin cell surface receptor linked signal transduction (GO:0007166);cell-cell signaling (GO:0007267);energy pathways (GO:0006091);glucose metabolism (GO:0006006);hormone activity (GO:0005179);insulin receptor binding (GO:0005158);lipid metabolism (GO:0006629);physiological process (GO:0007582) Insulin/IGF/relaxin (IPR004825) high 8.0498783131 206151_x_at ELA3A ELA3;ELA3A elastase 3A, pancreatic (protease E) cholesterol metabolism (GO:0008203);chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);pancreatic elastase I activity (GO:0008125);pancreatic elastase activity (GO:0008132);peptidase activity (GO:0008233);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 7.73659422337 206447_at ELA2A ELA2A elastase 2A chymotrypsin activity (GO:0004263);hydrolase activity (GO:0016787);pancreatic elastase II activity (GO:0004281);pancreatic elastase activity (GO:0008132);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 7.50641792356 205509_at CPB1 CPB1;PASP;PCPB carboxypeptidase B1 (tissue) carboxypeptidase A activity (GO:0004182);carboxypeptidase B activity (GO:0050425);carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);proteolysis and peptidolysis (GO:0006508) Peptidase M14, carboxypeptidase A (IPR000834);Proteinase inhibitor, carboxypeptidase propeptide (IPR003146);Proteinase inhibitor, propeptide (IPR009020) high 7.49663263984 213479_at NPTX2 NP-II;NP2;NPTX2 neuronal pentraxin II heterophilic cell adhesion (GO:0007157);lectin (GO:0005530);molecular_function unknown (GO:0005554);regulation of synapse (GO:0007273);sugar binding (GO:0005529);transport (GO:0006810) Concanavalin A-like lectin/glucanase (IPR008985);Pentaxin (IPR001759) high 7.42908012627 209189_at FOS FOS v-fos FBJ murine osteosarcoma viral oncogene homolog DNA binding (GO:0003677);DNA methylation (GO:0006306);cell growth and/or maintenance (GO:0008151);inflammatory response (GO:0006954);oncogenesis (GO:0007048);specific RNA polymerase II transcription factor activity (GO:0003704);transcription from Pol II promoter (GO:0006366) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Fos transforming protein (IPR000837) high 7.38152152071 205971_s_at CTRB1 CTRB;CTRB1 chymotrypsinogen B1 chymotrypsin activity (GO:0004263);digestion (GO:0007586);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);trypsin activity (GO:0004295) Peptidase S1, chymotrypsin (IPR001254);Peptidase S1A, chymotrypsin (IPR001314);Peptidase, trypsin-like serine and cysteine proteases (IPR009003) high 7.3511018299 217022_s_at MGC27165 MGC27165 hypothetical protein MGC27165 None Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) high 7.13975733194 209774_x_at CXCL2 CINC-2a;CXCL2;GRO2;GROb;MGSA-b;MIP-2a;MIP2;MIP2A;SCYB2 chemokine (C-X-C motif) ligand 2 G-protein coupled receptor protein signaling pathway (GO:0007186);chemokine activity (GO:0008009);chemotaxis (GO:0006935);cytokine activity (GO:0005125);immune response (GO:0006955);inflammatory response (GO:0006954) Small chemokine, C-X-C subfamily (IPR001089);Small chemokine, C-X-C/Interleukin 8 (IPR002473);Small chemokine, interleukin-8 like (IPR001811) low -8.70076150564 209351_at KRT14 CK14;EBS3;EBS4;K14;KRT14 keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) biological_process unknown (GO:0000004);structural constituent of cytoskeleton (GO:0005200);structural constituent of epidermis (GO:0030280) 14-3-3 protein (IPR000308);Intermediate filament protein (IPR001664);Keratin, type I (IPR002957);Tachykinin/Neurokinin (IPR002040) low -8.70521214337 213201_s_at TNNT1 ANM;TNNT1 troponin T1, skeletal, slow muscle development (GO:0007517);tropomyosin binding (GO:0005523) Bipartite nuclear localization signal (IPR001472);Proline-rich region (IPR000694);Troponin (IPR001978) low -8.78504445273 205388_at TNNC2 TNNC2 troponin C2, fast calcium ion binding (GO:0005509);muscle development (GO:0007517) Calcium-binding EF-hand (IPR002048) low -8.91970167502 205478_at PPP1R1A PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A glycogen metabolism (GO:0005977);protein phosphatase inhibitor activity (GO:0004864);signal transduction (GO:0007165);type 1 serine/threonine specific protein phosphatase inhibitor activity (GO:0004865) Protein phosphatase inhibitor, 1DARPP-32 (IPR008466) low -8.99631214858 209904_at TNNC1 TNC;TNNC;TNNC1 troponin C, slow calcium ion binding (GO:0005509);muscle development (GO:0007517) Calcium-binding EF-hand (IPR002048);Recoverin (IPR001125) low -9.09996382344 209888_s_at MYL1 MLC1F;MLC3F;MYL1 myosin, light polypeptide 1, alkali; skeletal, fast calcium ion binding (GO:0005509);muscle development (GO:0007517);structural constituent of muscle (GO:0008307) Calcium-binding EF-hand (IPR002048) low -10.0136511104 206117_at TPM1 CMH3;TMSA;TPM1 tropomyosin 1 (alpha) actin binding (GO:0003779);muscle development (GO:0007517);regulation of heart rate (GO:0008016);structural constituent of cytoskeleton (GO:0005200);structural constituent of muscle (GO:0008307) Beta-ketoacyl synthase (IPR000794);SF_assemblin (IPR008374);Tropomyosin (IPR000533) low -10.2749386925 204737_s_at MYH7 CMH1;MYH7;MYHCB myosin, heavy polypeptide 7, cardiac muscle, beta ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);microfilament motor activity (GO:0000146);motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928);Tropomyosin (IPR000533) low -11.6085750127 203872_at ACTA1 ACTA;ACTA1;ASMA;NEM1;NEM2 actin, alpha 1, skeletal muscle motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);structural constituent of cytoskeleton (GO:0005200) Actin (IPR004001);Actin/actin-like (IPR004000) low -11.7413493016 204810_s_at CKM CKM;CKMM;M-CK creatine kinase, muscle creatine kinase activity (GO:0004111);transferase activity, transferring phosphorus-containing groups (GO:0016772) ATP:guanido phosphotransferase (IPR000749)