PC-27 10 High/Low PC-27 Value ProbeId Name Aliases Description Function Protein Families high 7.92649519606 206373_at ZIC1 ZIC;ZIC1;ZNF201 Zic family member 1 (odd-paired homolog, Drosophila) DNA binding (GO:0003677);behavior (GO:0007610);development (GO:0007275);inner ear morphogenesis (GO:0042472);neurogenesis (GO:0007399);pattern specification (GO:0007389);regulation of smoothened receptor signaling pathway (GO:0008589);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270);zinc-mediated transcriptional activator activity (GO:0042156) Zn-finger, C2H2 type (IPR007087) high 7.27625604175 205350_at CRABP1 CRABP;CRABP-I;CRABP1;CRABPI;RBP5 cellular retinoic acid binding protein 1 development (GO:0007275);lipid binding (GO:0008289);retinoid binding (GO:0005501);signal transduction (GO:0007165);transport (GO:0006810);transporter activity (GO:0005215) Cytosolic fatty-acid binding protein (IPR000463);Lipocalin-related protein and Bos/Can/Equ allergen (IPR000566) high 5.83836452068 201131_s_at CDH1 CDH1;CDHE;ECAD;LCAM;UVO cadherin 1, type 1, E-cadherin (epithelial) calcium ion binding (GO:0005509);calcium-dependent cell adhesion molecule activity (GO:0008014);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515);tumor suppressor (GO:0008181) Cadherin (IPR002126);Cadherin cytoplasmic region (IPR000233) high 5.67015681256 209660_at TTR HsT2651;PALB;TBPA;TTR transthyretin (prealbumin, amyloidosis type I) carrier activity (GO:0005386);retinol binding (GO:0019841);steroid binding (GO:0005496);thyroid hormone generation (GO:0006590);thyroid hormone transporter activity (GO:0015349);transport (GO:0006810) Transthyretin (IPR000895) high 5.39419514857 210342_s_at TPO MSA;TPO;TPX thyroid peroxidase calcium ion binding (GO:0005509);iodide peroxidase activity (GO:0004447);oxidoreductase activity (GO:0016491);peroxidase activity (GO:0004601);response to oxidative stress (GO:0006979);thyroid hormone generation (GO:0006590) Animal haem peroxidase (IPR002007);EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);Haem peroxidase, plant/fungal/bacterial (IPR002016);Sushi domain/SCR domain/CCP module (IPR000436) high 5.2691083118 219564_at KCNJ16 KCNJ16;KIR5.1;MGC33717 potassium inwardly-rectifying channel, subfamily J, member 16 inward rectifier potassium channel activity (GO:0005242);ion transport (GO:0006811);potassium channel activity (GO:0005267);potassium ion transport (GO:0006813);voltage-gated ion channel activity (GO:0005244) K+ channel, inward rectifier (IPR001838);K+ channel, pore region (IPR001622);Kir5.0 inward rectifier K+ channel (IPR008061) high 5.24207306517 203872_at ACTA1 ACTA;ACTA1;ASMA;NEM1;NEM2 actin, alpha 1, skeletal muscle motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);structural constituent of cytoskeleton (GO:0005200) Actin (IPR004001);Actin/actin-like (IPR004000) high 5.23067943525 gnf1h00769_at ECRG4 ECRG4 esophageal cancer related gene 4 protein None None high 4.78865947391 216733_s_at GATM AGAT;GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) biosynthesis (GO:0009058);creatine biosynthesis (GO:0006601);glycine amidinotransferase activity (GO:0015068);transferase activity (GO:0016740) Amidinotransferase (IPR003198);TonB-dependent receptor (IPR000531) high 4.67235011193 205747_at CBLN1 CBLN1 cerebellin 1 precursor neurogenesis (GO:0007399) Complement C1q protein (IPR001073);TNF-like (IPR008983) low -7.00456344072 34210_at CDW52 CD52;CDW52 CDW52 antigen (CAMPATH-1 antigen) lymphocyte antigen (GO:0005557) None low -7.06631473349 203381_s_at APOE APOE apolipoprotein E antioxidant activity (GO:0016209);apolipoprotein E receptor binding (GO:0050749);beta-amyloid binding (GO:0001540);cholesterol homeostasis (GO:0042632);cholesterol metabolism (GO:0008203);circulation (GO:0008015);cytoskeleton organization and biogenesis (GO:0007010);development (GO:0007275);heparin binding (GO:0008201);immune response (GO:0006955);intracellular transport (GO:0046907);learning and/or memory (GO:0007611);lipid binding (GO:0008289);lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157);low-density lipoprotein receptor binding (GO:0050750);plasma protein (GO:0005209);receptor binding (GO:0005102);response to reactive oxygen species (GO:0000302);tau protein binding (GO:0048156) Apolipoprotein A1/A4/E (IPR000074) low -7.09822240651 206647_at HBZ HBZ hemoglobin, zeta globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Alpha haemoglobin (IPR002338);Bipartite nuclear localization signal (IPR001472);Globin (IPR000971);Myoglobin (IPR002335);Pi haemoglobin (IPR002339);Zeta haemoglobin (IPR002340) low -7.23415099652 206481_s_at LDB2 CLIM1;LDB1;LDB2 LIM domain binding 2 DNA binding (GO:0003677);development (GO:0007275);transcription activating factor (GO:0003710);transcription cofactor activity (GO:0003712) LIM binding protein (IPR002691) low -7.383677658 213435_at SATB2 FLJ21474;KIAA1034;SATB2 SATB family member 2 DNA binding (GO:0003677);transcription factor activity (GO:0003700) Cut homeobox (IPR007108);Homeobox (IPR001356);Homeodomain protein CUT (IPR003350) low -7.46360242505 213338_at RIS1 DKFZp586E1621;RIS1;p40BBP Ras-induced senescence 1 None Winged helix DNA-binding (IPR009058) low -7.48510772044 205421_at SLC22A3 EMT;EMTH;OCT3;SLC22A3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 ion transport (GO:0006811);ion transporter activity (GO:0015075);organic cation transport (GO:0015695);organic cation transporter activity (GO:0015101) General substrate transporter (IPR005828);Major facilitator superfamily (IPR007114);Organic cation transport protein (IPR004749);Sugar transporter superfamily (IPR005829) low -7.71874258005 gnf1h04129_x_at gnf1h04129_x_at None None None None low -8.23520359746 204081_at NRGN NRGN;RC3;hng neurogranin (protein kinase C substrate, RC3) calmodulin binding (GO:0005516);neurogenesis (GO:0007399);signal transduction (GO:0007165) IQ calmodulin-binding region (IPR000048) low -9.6797710381 204416_x_at APOC1 APOC1 apolipoprotein C-I lipid metabolism (GO:0006629);lipid transport (GO:0006869);lipid transporter activity (GO:0005319);lipoprotein metabolism (GO:0042157) Apolipoprotein C-I (IPR006781)