PC-45 10 High/Low PC-45 Value ProbeId Name Aliases Description Function Protein Families high 6.08812761577 gnf1h09377_at gnf1h09377_at None None None Ribosomal protein L24E (IPR000988) high 5.55247585589 207276_at CDR1 CDR;CDR1;CDR34;CDR62A cerebellar degeneration-related protein 1, 34kDa cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048) None high 5.48408085958 206702_at TEK CD202B;TEK;TIE-2;TIE2;VMCM;VMCM1 TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) ATP binding (GO:0005524);cell-cell signaling (GO:0007267);kinase activity (GO:0016301);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);protein-tyrosine kinase activity (GO:0004713);receptor activity (GO:0004872);signal transduction (GO:0007165);structural molecule activity (GO:0005198);transferase activity (GO:0016740);transmembrane receptor protein tyrosine kinase activity (GO:0004714);transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169) EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Fibronectin, type III (IPR003961);Fibronectin, type III-like fold (IPR008957);Immunoglobulin-like (IPR007110);Laminin-type EGF-like domain (IPR002049);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Type I EGF (IPR006210);Tyrosine protein kinase (IPR001245) high 5.31714043492 205391_x_at ANK1 ANK;ANK1;SPH1;SPH2 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 5.3160128204 gnf1h02643_at gnf1h02643_at None None None Cysteine-rich TIL region (IPR002919);von Willebrand factor, type D (IPR001846) high 5.30620483502 208352_x_at ANK1 ANK;ANK1;SPH1;SPH2 ankyrin 1, erythrocytic cytoskeletal adaptor activity (GO:0008093);cytoskeleton organization and biogenesis (GO:0007010);enzyme binding (GO:0019899);exocytosis (GO:0006887);maintenance of epithelial cell polarity (GO:0045199);signal transduction (GO:0007165);spectrin binding (GO:0030507);structural constituent of cytoskeleton (GO:0005200);structural molecule activity (GO:0005198) Death domain (IPR000488);Winged helix DNA-binding (IPR009058);ZU5 domain (IPR000906) high 5.1556442553 204694_at AFP AFP;FETA;HPAFP alpha-fetoprotein carrier activity (GO:0005386);immune response (GO:0006955);nickel ion binding (GO:0016151);plasma protein (GO:0005209);transport (GO:0006810) Alpha-fetoprotein (IPR001703);Serum albumin (IPR000264) high 5.06935253127 205725_at SCGB1A1 CC10;CC16;CCSP;SCGB1A1;UGB secretoglobin, family 1A, member 1 (uteroglobin) biological_process unknown (GO:0000004);cytokine activity (GO:0005125);embryo implantation (GO:0007566);histogenesis and organogenesis (GO:0007397);organogenesis (GO:0009887);phospholipase A2 inhibitor activity (GO:0019834);pregnancy (GO:0007565);signal transduction (GO:0007165);steroid binding (GO:0005496) Uteroglobin family (IPR006039);Uteroglobin subfamily (IPR000329);Uteroglobin subtype (IPR003628);Uteroglobin superfamily (IPR006038) high 5.06776982686 206647_at HBZ HBZ hemoglobin, zeta globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Alpha haemoglobin (IPR002338);Bipartite nuclear localization signal (IPR001472);Globin (IPR000971);Myoglobin (IPR002335);Pi haemoglobin (IPR002339);Zeta haemoglobin (IPR002340) high 5.01219967106 211843_x_at CYP3A7 CP37;CYP3A7;P450-HFLA cytochrome P450, family 3, subfamily A, polypeptide 7 cytochrome P450 activity (GO:0015034);electron transport (GO:0006118);monooxygenase activity (GO:0004497);oxidoreductase activity\, acting on paired donors\, with incorporation or reduction of molecular oxygen\, reduced flavin or flavoprotein as one donor\, and incorporation of one atom of oxygen (GO:0016712);oxygen binding (GO:0019825);xenobiotic metabolism (GO:0006805) B-class P450 (IPR002397);Bipartite nuclear localization signal (IPR001472);Cytochrome P450 (IPR001128);E-class P450, CYP3A (IPR008072);E-class P450, group I (IPR002401);E-class P450, group II (IPR002402);E-class P450, group IV (IPR002403) low -3.71421819741 219407_s_at LAMC3 DKFZp434E202;LAMC3 laminin, gamma 3 cell adhesion (GO:0007155);protein binding (GO:0005515);structural molecule activity (GO:0005198) Beta and gamma crystallin (IPR001064);Bipartite nuclear localization signal (IPR001472);EGF-like domain (IPR006209);Galactose-binding like (IPR008979);Laminin B (IPR000034);Laminin, N-terminal (IPR008211);Laminin, N-terminal 2 (IPR008212);Laminin-type EGF-like domain (IPR002049) low -3.72780410917 203434_s_at MME CALLA;CD10;MME;NEP membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) cell-cell signaling (GO:0007267);hydrolase activity (GO:0016787);metallopeptidase activity (GO:0008237);neprilysin activity (GO:0004245);oncogenesis (GO:0007048);proteolysis and peptidolysis (GO:0006508);zinc ion binding (GO:0008270) Peptidase M13 (IPR008753);Peptidase M13, neprilysin (IPR000718) low -3.93170328811 209395_at CHI3L1 CHI3L1;GP39;HC-gp39;HCGP-3P;YKL40 chitinase 3-like 1 (cartilage glycoprotein-39) extracellular matrix structural constituent (GO:0005201);hydrolase activity (GO:0016787);metabolism (GO:0008152) Glycoside hydrolase, family 18 (IPR001223);Sugar transporter superfamily (IPR005829) low -3.95015010419 214592_s_at SNAPC5 SNAP19;SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366) None low -3.98887538577 213988_s_at SAT SAT;SSAT spermidine/spermine N1-acetyltransferase acyltransferase activity (GO:0008415);diamine N-acetyltransferase activity (GO:0004145);transferase activity (GO:0016740) GCN5-related N-acetyltransferase (IPR000182) low -4.08921188979 205028_at TRO KIAA1114;MAGE-d3;MAGED3;TRO trophinin cell adhesion (GO:0007155);embryo implantation (GO:0007566);homophilic cell adhesion (GO:0007156);protein binding (GO:0005515) MAGE protein (IPR002190) low -4.14992955535 203662_s_at TMOD1 D9S57E;ETMOD;TMOD;TMOD1 tropomodulin 1 actin binding (GO:0003779);cytoskeletal regulator activity (GO:0008580);cytoskeleton organization and biogenesis (GO:0007010);tropomyosin binding (GO:0005523) Tropomodulin (IPR004934) low -4.3194575671 gnf1h00454_at APOL4 APOL-IV;APOL4;APOLIV apolipoprotein L, 4 lipid binding (GO:0008289);lipid transport (GO:0006869);lipoprotein metabolism (GO:0042157) Apolipoprotein L (IPR008405) low -4.69631005738 206676_at CEACAM8 CD66b;CD67;CEACAM8;CGM6;NCA-95 carcinoembryonic antigen-related cell adhesion molecule 8 immune response (GO:0006955);tumor antigen (GO:0008222) Actin-binding, actinin-type (IPR001589);Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -5.08098946712 209542_x_at IGF1 IGF1;IGFI insulin-like growth factor 1 (somatomedin C) DNA replication (GO:0006260);RAS protein signal transduction (GO:0007265);cell motility (GO:0006928);glycolate metabolism (GO:0009441);growth factor activity (GO:0008083);hormone activity (GO:0005179);insulin-like growth factor receptor binding (GO:0005159);muscle development (GO:0007517);physiological process (GO:0007582);positive regulation of cell proliferation (GO:0008284);prothoracicotrophic hormone activity (GO:0018445);signal transduction (GO:0007165);skeletal development (GO:0001501) Insulin/IGF/relaxin (IPR004825)