PC-9 35 High/Low PC-9 Value ProbeId Name Aliases Description Function Protein Families high 19.7365058092 209116_x_at HBB HBB hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 18.432173401 211699_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 18.3804022551 209301_at CA2 CA-II;CA2 carbonic anhydrase II carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) high 17.1984791645 217414_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.9830970517 209458_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.9020259661 204018_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.6596642494 gnf1h04131_x_at gnf1h04131_x_at None None None None high 16.6084120658 gnf1h04130_x_at gnf1h04130_x_at None None None None high 16.5721516104 211745_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 16.4595999748 gnf1h04129_x_at gnf1h04129_x_at None None None None high 16.327864071 gnf1h08167_s_at gnf1h08167_s_at None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) high 16.0750895461 gnf1h05066_x_at gnf1h05066_x_at None None None None high 16.0549282744 209930_s_at NFE2 NF-E2;NFE2;p45 nuclear factor (erythroid-derived 2), 45kDa circulation (GO:0008015);development (GO:0007275);hemostasis (GO:0007599);transcription coactivator activity (GO:0003713);transcription factor activity (GO:0003700);translation regulator activity (GO:0045182) Basic-leucine zipper (bZIP) transcription factor (IPR004827);Bipartite nuclear localization signal (IPR001472);Eukaryotic transcription factor, DNA-binding (IPR008917);Proline-rich region (IPR000694) high 15.6075336177 204848_x_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 15.2303010271 214414_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) high 15.163647107 211696_x_at HBB HBB hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 14.7033599431 202219_at SLC6A8 CRTR;CT1;SLC6A8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 creatine transport (GO:0015881);creatine transporter activity (GO:0005308);creatine:sodium symporter activity (GO:0005309);muscle contraction (GO:0006936);neurotransmitter transport (GO:0006836);neurotransmitter:sodium symporter activity (GO:0005328);small molecule transport (GO:0006832);symporter activity (GO:0015293);transport (GO:0006810) Creatine transporter (IPR002984);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504);Sodium:neurotransmitter symporter (IPR000175) high 14.6633372367 217232_x_at HBB HBB hemoglobin, beta oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050);Myoglobin (IPR002335) high 14.5868958223 209605_at TST MGC19578;RDS;TST thiosulfate sulfurtransferase (rhodanese) cyanate catabolism (GO:0009440);sulfate transport (GO:0008272);thiosulfate sulfurtransferase activity (GO:0004792);transferase activity (GO:0016740) Rhodanese-like (IPR001763);Thiosulfate sulfurtransferase (IPR001307) high 14.5436290959 209555_s_at CD36 CD36;FAT;GP3B;GP4;GPIV;PASIV;SCARB3 CD36 antigen (collagen type I receptor, thrombospondin receptor) blood coagulation (GO:0007596);cell adhesion (GO:0007155);fatty acid metabolism (GO:0006631);protein binding (GO:0005515);receptor activity (GO:0004872);transport (GO:0006810) Adhesion molecule CD36 (IPR005428);CD36 antigen (IPR002159) high 14.1651076337 206834_at HBD HBD hemoglobin, delta globin (GO:0001524);oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 14.1248331414 gnf1h04566_at gnf1h04566_at None None None None high 14.0708153118 209522_s_at CRAT CAT1;CRAT carnitine acetyltransferase acyl-CoA metabolism (GO:0006637);acyltransferase activity (GO:0008415);carnitine O-acetyltransferase activity (GO:0004092);energy derivation by oxidation of organic compounds (GO:0015980);energy pathways (GO:0006091);transferase activity (GO:0016740);transport (GO:0006810) Acyltransferase ChoActase/COT/CPT (IPR000542) high 13.9520519775 gnf1h04420_x_at gnf1h04420_x_at None None None None high 13.8214432912 206488_s_at CD36 CD36;FAT;GP3B;GP4;GPIV;PASIV;SCARB3 CD36 antigen (collagen type I receptor, thrombospondin receptor) blood coagulation (GO:0007596);cell adhesion (GO:0007155);fatty acid metabolism (GO:0006631);protein binding (GO:0005515);receptor activity (GO:0004872);transport (GO:0006810) Adhesion molecule CD36 (IPR005428);CD36 antigen (IPR002159) high 13.7346148827 213515_x_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 13.699999856 gnf1h05065_at gnf1h05065_at None None None None high 13.5816210869 201743_at CD14 CD14;NDUFA2 CD14 antigen GPI-anchored membrane-bound receptor (GO:0015025);NADH dehydrogenase (ubiquinone) activity (GO:0008137);NADH dehydrogenase activity (GO:0003954);antibacterial peptide activity (GO:0003797);apoptosis (GO:0006915);cell surface receptor linked signal transduction (GO:0007166);energy pathways (GO:0006091);immune response (GO:0006955);inflammatory response (GO:0006954);oxidoreductase activity (GO:0016491);peptidoglycan receptor activity (GO:0016019);phagocytosis (GO:0006909) Mitochondrial ribosome (IPR007741) high 13.0695559772 210613_s_at SYNGR1 MGC:1939;SYNGR1 synaptogyrin 1 transport (GO:0006810);transporter activity (GO:0005215) Marvel (IPR008253);TonB-dependent receptor (IPR000531) high 13.0646142752 204959_at MNDA MNDA myeloid cell nuclear differentiation antigen DNA binding (GO:0003677);cellular defense response (GO:0006968);translation regulator activity (GO:0045182) Bipartite nuclear localization signal (IPR001472);HIN-200/IF120x domain (IPR004021);Pyrin domain (IPR004020) high 12.8255046353 gnf1h04567_x_at gnf1h04567_x_at None None None None high 12.5381930517 202917_s_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 12.4658305743 206380_s_at PFC BFD;PFC;PFD;PROPERDIN properdin P factor, complement antibacterial peptide activity (GO:0003797);complement activity (GO:0003811);defense response to bacteria (GO:0042742);immune response (GO:0006955);plasma glycoprotein (GO:0005211) Surface protein from Gram-positive cocci, anchor region (IPR001899) high 12.3851147193 215047_at BIA2 BIA2;DKFZp434C091 BIA2 G-protein coupled receptor protein signaling pathway (GO:0007186);rhodopsin-like receptor activity (GO:0001584) B302, (SPRY)-like (IPR001870);Butyrophylin-like (IPR003879);Rhodopsin-like GPCR superfamily (IPR000276);SPRY-associated domain (IPR006574);SPla/RYanodine receptor SPRY (IPR003877) high 12.2724707935 205950_s_at CA1 CA1 carbonic anhydrase I carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) low -6.3293428046 217422_s_at CD22 CD22;SIGLEC-2 CD22 antigen antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);heterophilic cell adhesion (GO:0007157);immune response (GO:0006955);lectin (GO:0005530);protein binding (GO:0005515);sugar binding (GO:0005529) Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.43179760563 217378_x_at 217378_x_at None None None Immunoglobulin V-type (IPR003596);Immunoglobulin subtype (IPR003599);Immunoglobulin/major histocompatibility complex (IPR003006) low -6.48556473462 210915_x_at M15564 None None None None low -6.56096101359 215177_s_at ITGA6 CD49f;ITGA6 integrin, alpha 6 cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);cell-substrate junction assembly (GO:0007044);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872) Integrins alpha chain (IPR000413) low -6.58495094798 35974_at LRMP JAW1;LRMP lymphoid-restricted membrane protein hemocyte development (GO:0007516);vesicle fusion (GO:0006906) MRVI1 (IPR008677) low -6.59771703106 209306_s_at SWAP70 KIAA0640;SWAP-70;SWAP70 SWAP-70 protein calcium ion binding (GO:0005509) Bipartite nuclear localization signal (IPR001472);Calcium-binding EF-hand (IPR002048);Pleckstrin-like (IPR001849) low -6.62270216469 211635_x_at Hs.449011 None Partial mRNA for immunoglobulin heavy chain variable region (IGHV gene), isolate B-CLL G026 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) low -6.70471827614 202988_s_at RGS1 1R20;BL34;IER1;IR20;RGS1 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -6.77307090744 204674_at LRMP JAW1;LRMP lymphoid-restricted membrane protein hemocyte development (GO:0007516);vesicle fusion (GO:0006906) MRVI1 (IPR008677) low -6.84555480243 209558_s_at HIP1R HIP12;HIP1R;HIP3;KIAA0655 huntingtin interacting protein-1-related actin binding (GO:0003779);biological_process unknown (GO:0000004) Epsin N-terminal homology (IPR001026);I/LWEQ domain (IPR002558);Phosphoinositide-binding clathrin adaptor, N-terminal (IPR008943) low -6.9692555214 205047_s_at ASNS ASNS;TS11 asparagine synthetase asparagine biosynthesis (GO:0006529);asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);glutamine metabolism (GO:0006541);ligase activity (GO:0016874);metabolism (GO:0008152) Asparagine synthase (IPR001962);Asparagine synthase, glutamine-hydrolyzing (IPR006426);Glutamine amidotransferase, class-II (IPR000583) low -7.00289519391 205267_at POU2AF1 BOB1;OBF-1;OBF1;OCAB;POU2AF1 POU domain, class 2, associating factor 1 cell growth and/or maintenance (GO:0008151);humoral immune response (GO:0006959);transcription activating factor (GO:0003710);transcription coactivator activity (GO:0003713);transcription cofactor activity (GO:0003712);transcription from Pol II promoter (GO:0006366) Proline-rich region (IPR000694) low -7.05072902083 gnf1h08134_s_at na None similar to asparagine synthetase; glutamine-dependent asparagine synthetase; TS11 cell cycle control protein None None low -7.13798527174 210258_at RGS13 MGC17173;RGS13 regulator of G-protein signalling 13 signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -7.16305510025 gnf1h01164_at SEPT1 DIFF6;LARP;MGC20394;PNUTL3;SEP1;SEPT1 septin 1 GTP binding (GO:0005525);cytokinesis (GO:0016288) Cell division/GTP binding protein (IPR000038) low -7.16738994598 213856_at CD47 CD47;IAP;MER6;OA3 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) cell adhesion molecule activity (GO:0005194);cell-matrix adhesion (GO:0007160);integrin-mediated signaling pathway (GO:0007229);oncogenesis (GO:0007048);plasma glycoprotein (GO:0005211);protein binding (GO:0005515) CD47 integrin associated protein (IPR006704);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -7.17316097035 210538_s_at BIRC3 AIP1;API2;BIRC3;CIAP2;HAIP1;HIAP1;MIHC;RNF49 baculoviral IAP repeat-containing 3 apoptosis (GO:0006915);apoptosis inhibitor activity (GO:0008189);cell surface receptor linked signal transduction (GO:0007166);protein binding (GO:0005515) CARD interaction domain (IPR001315);Zn-finger, RING (IPR001841) low -7.22204486767 204960_at PTPRCAP CD45-AP;LPAP;PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein antimicrobial peptide activity (GO:0003795);defense response (GO:0006952) None low -7.38947006319 212592_at IGJ IGCJ;IGJ;JCH immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides antigen binding (GO:0003823);immune response (GO:0006955) None low -7.48057688392 204951_at RHOH ARHH;RHOH;TTF ras homolog gene family, member H GTP binding (GO:0005525);GTPase inhibitor activity (GO:0005095);Rho GTPase binding (GO:0017048);Rho small monomeric GTPase activity (GO:0003931);T-cell differentiation (GO:0030217);kinase inhibitor activity (GO:0019210);negative regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043124);oncogenesis (GO:0007048);small GTPase mediated signal transduction (GO:0007264) Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -7.53681741262 206255_at BLK BLK;MGC10442 B lymphoid tyrosine kinase ATP binding (GO:0005524);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein kinase cascade (GO:0007243);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -7.55546532344 205671_s_at HLA-DOB HLA-DOB major histocompatibility complex, class II, DO beta MHC class II receptor activity (GO:0045012);antigen presentation, exogenous antigen (GO:0019884);antigen processing, exogenous antigen via MHC class II (GO:0019886);class II major histocompatibility complex antigen (GO:0003821);immune response (GO:0006955) Class II histocompatibility antigen, beta chain, beta-1 domain (IPR000353);Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -7.6032371856 211634_x_at Hs.449011 None Partial mRNA for immunoglobulin heavy chain variable region (IGHV gene), isolate B-CLL G026 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110) low -8.03327767781 208456_s_at RRAS2 RRAS2;TC21 related RAS viral (r-ras) oncogene homolog 2 GTP binding (GO:0005525);GTPase activity (GO:0003924);RAS small monomeric GTPase activity (GO:0003930);cell growth and/or maintenance (GO:0008151);oncogenesis (GO:0007048);small GTPase mediated signal transduction (GO:0007264) GTP-binding nuclear protein Ran (IPR002041);Ras GTPase superfamily (IPR001806);Ras small GTPase, Rab type (IPR003579);Ras small GTPase, Ras type (IPR003577);Ras small GTPase, Rho type (IPR003578);Small GTP-binding protein domain (IPR005225) low -8.05421222176 201689_s_at TPD52 D52;N8L;PC-1;PrLZ;TPD52;hD52 tumor protein D52 morphogenesis (GO:0009653) Tumor protein D52 (IPR007327) low -8.0917966999 210448_s_at P2RX5 MGC47755;P2RX5;P2X5;P2X5R purinergic receptor P2X, ligand-gated ion channel, 5 ATP binding (GO:0005524);ion channel activity (GO:0005216);ion transport (GO:0006811);neurogenesis (GO:0007399);receptor activity (GO:0004872);signal transduction (GO:0007165);small molecule transport (GO:0006832);transmembrane receptor activity (GO:0004888);transport (GO:0006810) ATP P2X receptor (IPR001429);P2X5 purinoceptor (IPR003048) low -8.2765485352 216834_at RGS1 1R20;BL34;IER1;IR20;RGS1 regulator of G-protein signalling 1 B-cell activation (GO:0042113);G-protein signaling\, adenylate cyclase inhibiting pathway (GO:0007193);GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);immune response (GO:0006955);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -8.53194857797 201688_s_at TPD52 D52;N8L;PC-1;PrLZ;TPD52;hD52 tumor protein D52 morphogenesis (GO:0009653) Tumor protein D52 (IPR007327) low -8.80539740588 204352_at TRAF5 MGC:39780;RNF84;TRAF5 TNF receptor-associated factor 5 apoptosis (GO:0006915);astacin activity (GO:0008533);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);proteolysis and peptidolysis (GO:0006508);receptor activity (GO:0004872);signal transducer activity (GO:0004871);signal transduction (GO:0007165);zinc ion binding (GO:0008270) MATH (IPR002083);TRAF domain-like (IPR008974);Zn-finger, RING (IPR001841);Zn-finger, TRAF type (IPR001293) low -9.35615249773 211796_s_at 211796_s_at None None None Immunoglobulin C-type (IPR003597);Immunoglobulin/major histocompatibility complex (IPR003006) low -9.38413749717 205544_s_at CR2 C3DR;CD21;CR2 complement component (3d/Epstein Barr virus) receptor 2 complement receptor activity (GO:0004875);immune response (GO:0006955);transmembrane receptor activity (GO:0004888) Peptidase M14, carboxypeptidase A (IPR000834);Sushi domain/SCR domain/CCP module (IPR000436) low -9.51938476976 204891_s_at LCK LCK lymphocyte-specific protein tyrosine kinase ATP binding (GO:0005524);RAS protein signal transduction (GO:0007265);cell growth and/or maintenance (GO:0008151);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -9.55301074562 204890_s_at LCK LCK lymphocyte-specific protein tyrosine kinase ATP binding (GO:0005524);RAS protein signal transduction (GO:0007265);cell growth and/or maintenance (GO:0008151);intracellular signaling cascade (GO:0007242);protein amino acid phosphorylation (GO:0006468);protein binding (GO:0005515);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Protein kinase (IPR000719);SH2 motif (IPR000980);SH3 (IPR001452);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) low -9.59559184691 gnf1h09726_s_at gnf1h09726_s_at None None None None low -9.87661581837 201189_s_at ITPR3 IP3R3;ITPR3 inositol 1,4,5-triphosphate receptor, type 3 calcium channel activity (GO:0005262);calcium ion transport (GO:0006816);calcium ion transporter activity (GO:0015085);cation transport (GO:0006812);inositol 1\,4\,5-triphosphate-sensitive calcium-release channel activity (GO:0005220);inositol-1,4,5-triphosphate receptor activity (GO:0008095);receptor activity (GO:0004872);signal transduction (GO:0007165);small molecule transport (GO:0006832) Bipartite nuclear localization signal (IPR001472);Ca2+/Na+ channel, pore region (IPR001682);Inositol 1,4,5-trisphosphate-binding protein receptor (IPR000493);Intracellular calcium-release channel (IPR000699);Ion transport protein (IPR005821);Legume lectin, beta domain (IPR001220);MIR domain (IPR003608)