PC-11 35 High/Low PC-11 Value ProbeId Name Aliases Description Function Protein Families high 14.6302527707 gnf1h04566_at gnf1h04566_at None None None None high 13.2695672265 204083_s_at TPM2 AMCD1;DA1;TMSB;TPM2 tropomyosin 2 (beta) actin binding (GO:0003779);muscle development (GO:0007517);structural constituent of muscle (GO:0008307) Tropomyosin (IPR000533) high 12.0985505091 gnf1h04129_x_at gnf1h04129_x_at None None None None high 11.4335633373 gnf1h05065_at gnf1h05065_at None None None None high 11.2642651486 201105_at LGALS1 FLJ21318;GBP;LGALS1;PDXP;PLP;SH3BP1;dJ37E16;dJ37E16.5 lectin, galactoside-binding, soluble, 1 (galectin 1) apoptosis (GO:0006915);galactose binding (GO:0005534);galactose binding lectin (GO:0005531);heterophilic cell adhesion (GO:0007157);hydrolase activity (GO:0016787);lectin (GO:0005530);metabolism (GO:0008152);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871);sugar binding (GO:0005529) 2-phosphoglycolate phosphatase, eukaryotic (IPR006349);Concanavalin A-like lectin/glucanase (IPR008985);Galectin, galactose-binding lectin (IPR001079);HAD-superfamily hydrolase, subfamily IIA (IPR006357);Haloacid dehalogenase-like hydrolase (IPR005834);Proline-rich region (IPR000694);Rho GTPase activation protein (IPR008936);RhoGAP domain (IPR000198) high 11.2425797923 gnf1h04567_x_at gnf1h04567_x_at None None None None high 10.7096430861 209904_at TNNC1 TNC;TNNC;TNNC1 troponin C, slow calcium ion binding (GO:0005509);muscle development (GO:0007517) Calcium-binding EF-hand (IPR002048);Recoverin (IPR001125) high 10.5843670689 gnf1h04131_x_at gnf1h04131_x_at None None None None high 10.2643491336 gnf1h05066_x_at gnf1h05066_x_at None None None None high 10.2219633908 gnf1h04130_x_at gnf1h04130_x_at None None None None high 9.91193284508 204857_at MAD1L1 HsMAD1;MAD1;MAD1L1;PIG9;TP53I9;TXBP181 MAD1 mitotic arrest deficient-like 1 (yeast) cell proliferation (GO:0008283);molecular_function unknown (GO:0005554) Bipartite nuclear localization signal (IPR001472);Mitotic checkpoint (IPR008672) high 9.9077040015 201841_s_at HSPB1 HS.76067;HSP27;HSP28;HSPB1;Hsp25 heat shock 27kDa protein 1 heat shock protein activity (GO:0003773) Alpha crystallin (IPR001436);HSP20-like chaperone (IPR008978);Heat shock protein Hsp20 (IPR002068) high 9.7934615621 202222_s_at DES CMD1I;CSM1;CSM2;DES;FLJ12025 desmin cytoskeleton organization and biogenesis (GO:0007010);muscle contraction (GO:0006936);muscle development (GO:0007517);regulation of heart rate (GO:0008016);structural constituent of cytoskeleton (GO:0005200) Intermediate filament protein (IPR001664);Intermediate filament, DNA-binding region (IPR006821) high 9.5672012642 219922_s_at LTBP3 DKFZP586M2123;LTBP2;LTBP3 latent transforming growth factor beta binding protein 3 calcium ion binding (GO:0005509) EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Growth factor, receptor (IPR009030);Matrix fibril-associated (IPR002212);Proline-rich region (IPR000694) high 9.55553811508 gnf1h04420_x_at gnf1h04420_x_at None None None None high 9.52277811625 204737_s_at MYH7 CMH1;MYH7;MYHCB myosin, heavy polypeptide 7, cardiac muscle, beta ATP binding (GO:0005524);actin binding (GO:0003779);calmodulin binding (GO:0005516);microfilament motor activity (GO:0000146);motor activity (GO:0003774);muscle contraction (GO:0006936);muscle development (GO:0007517);protein amino acid alkylation (GO:0008213);striated muscle contraction (GO:0006941);structural constituent of muscle (GO:0008307) IQ calmodulin-binding region (IPR000048);Myosin N-terminal SH3-like domain (IPR004009);Myosin head (motor domain) (IPR001609);Myosin tail (IPR002928);Tropomyosin (IPR000533) high 9.5146291674 200671_s_at SPTBN1 DKFZp547I014;SPTB2;SPTBN1 spectrin, beta, non-erythrocytic 1 RNA binding (GO:0003723);actin binding (GO:0003779);protein biosynthesis (GO:0006412);structural constituent of cytoskeleton (GO:0005200);structural constituent of ribosome (GO:0003735) Actin-binding, actinin-type (IPR001589);Bipartite nuclear localization signal (IPR001472);Calponin-like actin-binding (IPR001715);Pleckstrin-like (IPR001849);Ribosomal L23 protein (IPR001014);Ribosomal protein L23, N-terminal domain (IPR005633);Spectrin/pleckstrin-like (IPR001605) high 9.23432192761 206117_at TPM1 CMH3;TMSA;TPM1 tropomyosin 1 (alpha) actin binding (GO:0003779);muscle development (GO:0007517);regulation of heart rate (GO:0008016);structural constituent of cytoskeleton (GO:0005200);structural constituent of muscle (GO:0008307) Beta-ketoacyl synthase (IPR000794);SF_assemblin (IPR008374);Tropomyosin (IPR000533) high 9.06399312601 217165_x_at 217165_x_at None metallothionein 1F (functional) None None high 9.0483985799 204862_s_at NME3 DR-nm23;NME3 non-metastatic cells 3, protein expressed in ATP binding (GO:0005524);CTP biosynthesis (GO:0006241);GTP biosynthesis (GO:0006183);UTP biosynthesis (GO:0006228);apoptosis (GO:0006915);kinase activity (GO:0016301);nucleoside-diphosphate kinase activity (GO:0004550);transferase activity (GO:0016740) Bipartite nuclear localization signal (IPR001472);Nucleoside diphosphate kinase (IPR001564) high 8.93557913793 204021_s_at PURA PUR-ALPHA;PUR1;PURA;PURALPHA purine-rich element binding protein A RNA polymerase II transcription factor activity, enhancer binding (GO:0003705);single-stranded DNA binding (GO:0003697);translation regulator activity (GO:0045182) PUR-alpha/beta/gamma, DNA/RNA-binding (IPR006628) high 8.91603286961 204810_s_at CKM CKM;CKMM;M-CK creatine kinase, muscle creatine kinase activity (GO:0004111);transferase activity, transferring phosphorus-containing groups (GO:0016772) ATP:guanido phosphotransferase (IPR000749) high 8.89912605872 gnf1h07166_at DKFZp761P0423 DKFZp761P0423 hypothetical protein DKFZp761P0423 ATP binding (GO:0005524);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);transferase activity (GO:0016740) Aldehyde dehydrogenase (IPR002086);Protein kinase (IPR000719) high 8.84706994638 gnf1h04798_x_at gnf1h04798_x_at None None None None high 8.82586947641 gnf1h08794_s_at SIAHBP1 FIR;PUF60;RoBPI;SIAHBP1 fuse-binding protein-interacting repressor nucleic acid binding (GO:0003676) Poly-U binding splicing factor, half-pint (IPR006532);RNA-binding region RNP-1 (RNA recognition motif) (IPR000504) high 8.82024898848 gnf1h05601_x_at gnf1h05601_x_at None None None None high 8.77008130779 gnf1h03172_at gnf1h03172_at None None None None high 8.69165437984 203891_s_at DAPK3 DAPK3;ZIP;ZIPK death-associated protein kinase 3 ATP binding (GO:0005524);apoptosis (GO:0006915);protein amino acid phosphorylation (GO:0006468);protein kinase cascade (GO:0007243);protein serine/threonine kinase activity (GO:0004674);protein-tyrosine kinase activity (GO:0004713);transferase activity (GO:0016740) Bipartite nuclear localization signal (IPR001472);Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 8.67058383243 gnf1h06630_s_at gnf1h06630_s_at None None None None high 8.61025044438 207722_s_at BTBD2 BTBD2;FLJ20386 BTB (POZ) domain containing 2 protein binding (GO:0005515) BTB/POZ (IPR000210) high 8.51668575402 204149_s_at GSTM4 GSTM4;GSTM4-4;GTM4;MGC9247 glutathione S-transferase M4 glutathione transferase activity (GO:0004364);metabolism (GO:0008152);transferase activity (GO:0016740) Glutathione S-transferase, C-terminal (IPR004046);Glutathione S-transferase, Mu class (IPR003081);Glutathione S-transferase, N-terminal (IPR004045) high 8.51482701478 222060_at LOC90133 LOC90133 hypothetical protein LOC90133 None None high 8.50657757337 211160_x_at ACTN1 ACTN1 actinin, alpha 1 actin binding (GO:0003779);calcium ion binding (GO:0005509);structural constituent of cytoskeleton (GO:0005200) Actin-binding, actinin-type (IPR001589);Calcium-binding EF-hand (IPR002048);Calponin-like actin-binding (IPR001715) high 8.47333267226 206116_s_at TPM1 CMH3;TMSA;TPM1 tropomyosin 1 (alpha) actin binding (GO:0003779);muscle development (GO:0007517);regulation of heart rate (GO:0008016);structural constituent of cytoskeleton (GO:0005200);structural constituent of muscle (GO:0008307) Beta-ketoacyl synthase (IPR000794);SF_assemblin (IPR008374);Tropomyosin (IPR000533) high 8.43941627817 205766_at TCAP CMD1N;LGMD2G;T-cap;TCAP;TELE;telethonin titin-cap (telethonin) protein complex assembly (GO:0006461);structural constituent of muscle (GO:0008307) None low -6.18843500783 202833_s_at SERPINA1 A1A;A1AT;AAT;PI1;SERPINA1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 acute-phase response (GO:0006953);protein binding (GO:0005515);serine-type endopeptidase inhibitor activity (GO:0004867) Proteinase inhibititor I4, serpin (IPR000215) low -6.22418650723 209555_s_at CD36 CD36;FAT;GP3B;GP4;GPIV;PASIV;SCARB3 CD36 antigen (collagen type I receptor, thrombospondin receptor) blood coagulation (GO:0007596);cell adhesion (GO:0007155);fatty acid metabolism (GO:0006631);protein binding (GO:0005515);receptor activity (GO:0004872);transport (GO:0006810) Adhesion molecule CD36 (IPR005428);CD36 antigen (IPR002159) low -6.28423980518 204419_x_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) low -6.28871406626 204446_s_at ALOX5 ALOX5;LOG5 arachidonate 5-lipoxygenase arachidonate 5-lipoxygenase activity (GO:0004051);electron transport (GO:0006118);inflammatory response (GO:0006954);iron ion binding (GO:0005506);leukotriene biosynthesis (GO:0019370);leukotriene metabolism (GO:0006691);lipoxygenase activity (GO:0016165);oxidoreductase activity (GO:0016491) Bipartite nuclear localization signal (IPR001472);Lipase/lipooxygenase, PLAT/LH2 (IPR008976);Lipoxygenase (IPR000907);Lipoxygenase, LH2 domain (IPR001024);Mammalian lipoxygenase (IPR001885) low -6.31645171729 202648_at RPS19 DBA;RPS19 ribosomal protein S19 RNA binding (GO:0003723);hemocyte development (GO:0007516);oncogenesis (GO:0007048);protein biosynthesis (GO:0006412);structural constituent of ribosome (GO:0003735) Ribosomal protein S19e (IPR001266);Winged helix DNA-binding (IPR009058) low -6.36060645339 209138_x_at IGL@ IGL;IGL@ immunoglobulin lambda locus None None low -6.4223224565 205844_at VNN1 Tiff66;VNN1 vanin 1 cell motility (GO:0006928);hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);nitrogen metabolism (GO:0006807) Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (IPR003010) low -6.45935759732 204848_x_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) low -6.46098331138 213350_at RPS11 RPS11 ribosomal protein S11 RNA binding (GO:0003723);protein biosynthesis (GO:0006412);rRNA binding (GO:0019843);structural constituent of ribosome (GO:0003735) Bipartite nuclear localization signal (IPR001472);Nucleic acid-binding OB-fold (IPR008994);Ribosomal protein S17 (IPR000266) low -6.46512964267 220088_at GPR77 C5A;C5AR;C5L2;C5R1;CD88;GPR77 G protein-coupled receptor 77 C5a anaphylatoxin receptor activity (GO:0004944);G-protein coupled receptor activity, unknown ligand (GO:0016526);G-protein coupled receptor protein signaling pathway (GO:0007186);biological_process unknown (GO:0000004);cellular defense response (GO:0006968);chemotaxis (GO:0006935);immune response (GO:0006955);rhodopsin-like receptor activity (GO:0001584);sensory perception of chemical stimulus (GO:0007606);signal transduction (GO:0007165) Anaphylatoxin chemotactic receptor (IPR002234);Bradykinin receptor (IPR000496);C5A-anaphylatoxin receptor (IPR001274);Formyl/methionyl peptide receptor (IPR000826);Rhodopsin-like GPCR superfamily (IPR000276) low -6.5614290742 gnf1h08166_at gnf1h08166_at None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) low -6.57910932904 217414_x_at HBA2 HBA1;HBA2 hemoglobin, alpha 2 oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);protein binding (GO:0005515);transport (GO:0006810) Alpha haemoglobin (IPR002338);Globin (IPR000971);Globin-like (IPR009050);Pi haemoglobin (IPR002339) low -6.7723526104 202388_at RGS2 G0S8;RGS2 regulator of G-protein signalling 2, 24kDa GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);oncogenesis (GO:0007048);regulation of G-protein coupled receptor protein signaling pathway (GO:0008277);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Regulator of G protein (IPR000342) low -7.0421082315 266_s_at CD24 CD24;CD24A CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None low -7.05479023309 208146_s_at CPVL CPVL;HVLP;MGC10029 carboxypeptidase, vitellogenic-like carboxypeptidase activity (GO:0004180);hydrolase activity (GO:0016787);proteolysis and peptidolysis (GO:0006508);serine carboxypeptidase activity (GO:0004185) Beta and gamma crystallin (IPR001064);Esterase/lipase/thioesterase (IPR000379);Peptidase S10, serine carboxypeptidase (IPR001563) low -7.22731892427 215047_at BIA2 BIA2;DKFZp434C091 BIA2 G-protein coupled receptor protein signaling pathway (GO:0007186);rhodopsin-like receptor activity (GO:0001584) B302, (SPRY)-like (IPR001870);Butyrophylin-like (IPR003879);Rhodopsin-like GPCR superfamily (IPR000276);SPRY-associated domain (IPR006574);SPla/RYanodine receptor SPRY (IPR003877) low -7.44739642441 201743_at CD14 CD14;NDUFA2 CD14 antigen GPI-anchored membrane-bound receptor (GO:0015025);NADH dehydrogenase (ubiquinone) activity (GO:0008137);NADH dehydrogenase activity (GO:0003954);antibacterial peptide activity (GO:0003797);apoptosis (GO:0006915);cell surface receptor linked signal transduction (GO:0007166);energy pathways (GO:0006091);immune response (GO:0006955);inflammatory response (GO:0006954);oxidoreductase activity (GO:0016491);peptidoglycan receptor activity (GO:0016019);phagocytosis (GO:0006909) Mitochondrial ribosome (IPR007741) low -7.46490508132 209771_x_at CD24 CD24;CD24A CD24 antigen (small cell lung carcinoma cluster 4 antigen) humoral immune response (GO:0006959) None low -7.52936473766 203645_s_at CD163 CD163;M130;MM130 CD163 antigen antimicrobial humoral response (sensu Protostomia) (GO:0006960);antimicrobial humoral response (sensu Vertebrata) (GO:0019735);biological_process unknown (GO:0000004);copper ion binding (GO:0005507);protein-lysine 6-oxidase activity (GO:0004720);scavenger receptor activity (GO:0005044) Lysyl oxidase (IPR001695);Speract/scavenger receptor (IPR001190) low -7.60625927911 214370_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) low -7.97832363263 203535_at S100A9 60B8AG;CAGB;CFAG;CGLB;L1AG;LIAG;MAC387;MIF;MRP14;NIF;P14;S100A9 S100 calcium binding protein A9 (calgranulin B) calcium ion binding (GO:0005509);cell-cell signaling (GO:0007267);inflammatory response (GO:0006954);signal transducer activity (GO:0004871) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) low -8.03210704745 201427_s_at SEPP1 SEPP1;SeP selenoprotein P, plasma, 1 response to oxidative stress (GO:0006979);selenium binding (GO:0008430) Selenoprotein P, C-terminal (IPR007672);Selenoprotein P, N-terminal (IPR007671) low -8.05346105789 214677_x_at IGLJ3 IGLJ3;LOC96610 immunoglobulin lambda joining 3 antigen binding (GO:0003823);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin V-type (IPR003596);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006) low -8.18481962308 204959_at MNDA MNDA myeloid cell nuclear differentiation antigen DNA binding (GO:0003677);cellular defense response (GO:0006968);translation regulator activity (GO:0045182) Bipartite nuclear localization signal (IPR001472);HIN-200/IF120x domain (IPR004021);Pyrin domain (IPR004020) low -8.2202667577 gnf1h08167_s_at gnf1h08167_s_at None None None ABC transporter (IPR003439);Alpha haemoglobin (IPR002338);Beta haemoglobin (IPR002337);Globin (IPR000971) low -8.22197214987 203680_at PRKAR2B PRKAR2;PRKAR2B;RII-BETA protein kinase, cAMP-dependent, regulatory, type II, beta cAMP-dependent protein kinase regulator activity (GO:0008603);intracellular signaling cascade (GO:0007242) Cyclic nucleotide-binding domain (IPR000595);cAMP-dependent protein kinase (IPR002373);cAMP-dependent protein kinase regulator, type II PKA R subunit (IPR003117) low -8.22209522249 209301_at CA2 CA-II;CA2 carbonic anhydrase II carbonate dehydratase activity (GO:0004089);lyase activity (GO:0016829);one-carbon compound metabolism (GO:0006730);zinc ion binding (GO:0008270) Carbonic anhydrase, eukaryotic (IPR001148) low -8.26993691917 208894_at HLA-DRA HLA-DRA;HLA-DRA1 major histocompatibility complex, class II, DR alpha MHC class II receptor activity (GO:0045012);antigen presentation, exogenous antigen (GO:0019884);antigen processing, exogenous antigen via MHC class II (GO:0019886);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);MHC Class II alpha chain, alpha-1 domain (IPR001003) low -8.50538427042 212224_at ALDH1A1 ALDC;ALDH-E1;ALDH1;ALDH11;ALDH1A1;MGC2318;PUMB1;RALDH1 aldehyde dehydrogenase 1 family, member A1 aldehyde dehydrogenase (NAD) activity (GO:0004029);aldehyde metabolism (GO:0006081);androgen binding (GO:0005497);electron transporter activity (GO:0005489);oxidoreductase activity (GO:0016491) Aldehyde dehydrogenase (IPR002086) low -8.70724844734 gnf1h09726_s_at gnf1h09726_s_at None None None None low -9.38923724287 202917_s_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) low -9.60210350009 202018_s_at LTF HLF2;LTF lactotransferrin ferric iron binding (GO:0008199);humoral immune response (GO:0006959);iron ion binding (GO:0005506);iron ion homeostasis (GO:0006879);iron ion transport (GO:0006826);serine-type endopeptidase activity (GO:0004252);transport (GO:0006810);xenobiotic metabolism (GO:0006805) Bipartite nuclear localization signal (IPR001472);Peptidase S60, transferrin lactoferrin (IPR001156) low -10.1529556234 gnf1h09294_s_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) low -12.5839420676 210982_s_at HLA-DRA HLA-DRA;HLA-DRA1 major histocompatibility complex, class II, DR alpha MHC class II receptor activity (GO:0045012);antigen presentation, exogenous antigen (GO:0019884);antigen processing, exogenous antigen via MHC class II (GO:0019886);immune response (GO:0006955) Immunoglobulin C-type (IPR003597);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);MHC Class II alpha chain, alpha-1 domain (IPR001003) low -13.8420644798 213975_s_at LYZ LYZ lysozyme (renal amyloidosis) amyloid protein (GO:0005208);antimicrobial humoral response (sensu Protostomia) (GO:0006960);bacteriolytic toxin activity (GO:0015642);carbohydrate metabolism (GO:0005975);cell wall catabolism (GO:0016998);cytolysis (GO:0019835);hydrolase activity, acting on glycosyl bonds (GO:0016798);inflammatory response (GO:0006954);lysin activity (GO:0015465);lysozyme activity (GO:0003796);structural molecule activity (GO:0005198) Glycoside hydrolase, family 22 (IPR001916);Glycoside hydrolase, family 22, lysozyme (IPR000974)