PC-50 35 High/Low PC-50 Value ProbeId Name Aliases Description Function Protein Families high 5.48448592451 207846_at POU1F1 GHF-1;PIT1;POU1F1 POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) histogenesis and organogenesis (GO:0007397);negative regulation of cell proliferation (GO:0008285);organogenesis (GO:0009887);transcription factor activity (GO:0003700);transcription from Pol II promoter (GO:0006366);translation regulator activity (GO:0045182) Homeobox (IPR001356);POU domain (IPR000327);POU homeobox (IPR007103) high 5.11294953913 203186_s_at S100A4 18A2;42A;CAPL;MTS1;P9KA;PEL98;S100A4 S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) calcium ion binding (GO:0005509);invasive growth (GO:0007125) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) high 4.96353661355 217299_s_at NBS1 AT-V1;AT-V2;ATV;NBS;NBS1;NIBRIN Nijmegen breakage syndrome 1 (nibrin) DNA repair protein (GO:0003685);damaged DNA binding (GO:0003684);double-strand break repair (GO:0006302) BRCT (IPR001357);Forkhead-associated (FHA) (IPR000253);SMAD/FHA (IPR008984) high 4.74120090068 206157_at PTX3 PTX3;TSG-14 pentaxin-related gene, rapidly induced by IL-1 beta inflammatory response (GO:0006954) Concanavalin A-like lectin/glucanase (IPR008985);Pentaxin (IPR001759) high 4.70704689732 gnf1h08251_at FLJ12303 FLJ12303;KIAA1801 hypothetical protein FLJ12303 None IQ calmodulin-binding region (IPR000048) high 4.68161985303 gnf1h03129_at LOC348174 LOC348174;MGC34761 secretory protein LOC348174 sugar binding (GO:0005529) Allergen V5/Tpx-1 related (IPR001283);C-type lectin (IPR001304);EGF-like domain (IPR006209);EGF-like domain, subtype 2 (IPR000742);Type I EGF (IPR006210) high 4.68023057615 213443_at TRADD Hs.89862;MGC11078;TRADD TNFRSF1A-associated via death domain apoptosis (GO:0006915);positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Death domain (IPR000488);Proline-rich region (IPR000694) high 4.64038283701 217194_at AB007970 None None None None high 4.61944916632 205910_s_at CEL BAL;BSDL;BSSL;CEL;CELL;CEase;FAP;FAPP;LIPA carboxyl ester lipase (bile salt-stimulated lipase) catalytic activity (GO:0003824);cell differentiation (GO:0030154);cell growth (GO:0016049);cholesterol catabolism (GO:0006707);fat-soluble vitamin catabolism (GO:0042363);hydrolase activity (GO:0016787);lipase activity (GO:0016298);lipid catabolism (GO:0016042);lipid metabolism (GO:0006629);protein binding (GO:0005515);serine esterase activity (GO:0004759);sterol esterase activity (GO:0004771) Carboxylesterase, type B (IPR002018);Cholinesterase (IPR000997);Esterase/lipase/thioesterase (IPR000379);Proline-rich region (IPR000694) high 4.39047037653 206091_at MATN3 EDM5;HOA;MATN3 matrilin 3 extracellular matrix structural constituent (GO:0005201);skeletal development (GO:0001501) EGF-like calcium-binding (IPR001881);EGF-like domain (IPR006209);Type I EGF (IPR006210);von Willebrand factor, type A (IPR002035) high 4.36569172977 208546_x_at HIST1H2BH H2B/j;H2BFJ;HIST1H2BH histone 1, H2bh DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H2B (IPR000558);Histone core (IPR007125);Histone-fold (IPR009072);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 4.31286313825 216948_at 216948_at None Human DNA sequence from clone 263J7 on chromosome 6q14.3-15. Contains an RPL7 (60S Ribosomal Protein L7) pseudogene, a RAB1 (RAB1, member RAS oncogene family) pseudogene, ESTs, an STS and GSSs None None high 4.16508807787 206752_s_at DFFB CAD;CPAN;DFF-40;DFF2;DFF40;DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) DNA fragmentation (GO:0006309);apoptosis (GO:0006915);apoptosis regulator activity (GO:0016329);caspase-activated deoxyribonuclease activity (GO:0004537);hydrolase activity (GO:0016787);intracellular signaling cascade (GO:0007242);nuclease activity (GO:0004518);protein binding (GO:0005515) Caspase-activated nuclease CIDE-N (IPR003508) high 4.13424511724 210429_at RHCE RH30A;RHC;RHCE;RHE;RHIXB;RHPI;Rh4;RhVI;RhVIII Rhesus blood group, CcEe antigens ammonium transporter activity (GO:0008519);blood group antigen (GO:0005555);transport (GO:0006810);transporter activity (GO:0005215) Ammonium transporter (IPR001905);Blood group Rhesus C/E and D polypeptide (IPR002229);Rh-like protein/ammonium transporter (IPR010256) high 4.07648486978 208607_s_at SAA1 PIG4;SAA;SAA1;TP53I4 serum amyloid A1 acute-phase response (GO:0006953);high-density lipoprotein (GO:0005321);inflammatory response (GO:0006954);lipid transporter activity (GO:0005319) Serum amyloid A protein (IPR000096) high 4.067463561 gnf1h10571_at gnf1h10571_at None None None None high 4.06148729847 211837_s_at PTCRA PT-ALPHA;PTA;PTCRA pre T-cell antigen receptor alpha None None high 4.02868491422 215071_s_at HIST1H2AC H2A/l;H2AFL;HIST1H2AC;dJ221C16.4 histone 1, H2ac DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Histone H2A (IPR002119);Histone core (IPR007125);Histone-fold (IPR009072);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 4.02675549511 204848_x_at HBG1 HBG1;HBGA;HBGR hemoglobin, gamma A oxygen transport (GO:0015671);oxygen transporter activity (GO:0005344);transport (GO:0006810) Beta haemoglobin (IPR002337);Globin (IPR000971);Globin-like (IPR009050) high 4.01925453742 210432_s_at SCN3A NAC3;SCN3A sodium channel, voltage-gated, type III, alpha calcium ion binding (GO:0005509);cation channel activity (GO:0005261);cation transport (GO:0006812);sodium ion transport (GO:0006814);voltage-gated sodium channel activity (GO:0005248) Bipartite nuclear localization signal (IPR001472);Ca2+/Na+ channel, pore region (IPR001682);Cation (not K+) channel, TM region (IPR002111);Cation channel, non-ligand gated (IPR005820);IQ calmodulin-binding region (IPR000048);Ion transport protein (IPR005821);Na+ channel (IPR001696);Polycystic kidney disease type 2 protein (IPR003915);Sodium ion transport-associated (IPR010526) high 3.99143927838 209173_at AGR2 AG2;AGR2;GOB-4;HAG-2;XAG-2 anterior gradient 2 homolog (Xenopus laevis) oncogenesis (GO:0007048) None high 3.88867655385 204347_at AK3 AK3;AK4 adenylate kinase 3 ATP binding (GO:0005524);GTP binding (GO:0005525);adenylate kinase activity (GO:0004017);kinase activity (GO:0016301);nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0006139);phosphotransferase activity, phosphate group as acceptor (GO:0016776);transferase activity (GO:0016740) Adenylate kinase (IPR000850);Adenylate kinase, lid region (IPR007862);Adenylate kinase, subfamily (IPR006259);Shikimate kinase (IPR000623) high 3.84844214664 201670_s_at MARCKS 80K-L;MACS;MARCKS;MRACKS;PKCSL;PRKCSL myristoylated alanine-rich protein kinase C substrate actin cross-linking activity (GO:0003780);calmodulin binding (GO:0005516);cell motility (GO:0006928) Bipartite nuclear localization signal (IPR001472);Myristoylated alanine-rich C-kinase substrate MARCKS (IPR002101) high 3.83154462918 201656_at ITGA6 CD49f;ITGA6 integrin, alpha 6 cell adhesion receptor activity (GO:0004895);cell-matrix adhesion (GO:0007160);cell-substrate junction assembly (GO:0007044);integrin-mediated signaling pathway (GO:0007229);protein binding (GO:0005515);receptor activity (GO:0004872) Integrins alpha chain (IPR000413) high 3.76166073041 gnf1h09164_at gnf1h09164_at None None None Ubiquitin-conjugating enzymes (IPR000608) high 3.7540143861 219300_s_at CNTNAP2 CASPR2;CNTNAP2;NRXN4 contactin associated protein-like 2 cell adhesion (GO:0007155);protein binding (GO:0005515);structural molecule activity (GO:0005198);transmission of nerve impulse (GO:0019226) Coagulation factor 5/8 type C domain (FA58C) (IPR000421);Concanavalin A-like lectin/glucanase (IPR008985);EGF-like domain (IPR006209);Fibrinogen, beta/gamma chain, C-terminal globular (IPR002181);Galactose-binding like (IPR008979);Gonadotropin, beta chain (IPR001545);Laminin G (IPR001791);Neurexin/syndecan/glycophorin C (IPR003585);Type I EGF (IPR006210) high 3.74443070741 217966_s_at C1orf24 C1orf24;NIBAN chromosome 1 open reading frame 24 biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554);transport (GO:0006810) Heat shock protein DnaJ, N-terminal (IPR001623) high 3.67523376521 215779_s_at HIST1H2BG H2B.1A;H2B/a;H2B/g;H2BFA;H2BFG;HIST1H2BF;HIST1H2BG histone 1, H2bg DNA binding (GO:0003677);chromosome organization and biogenesis (sensu Eukarya) (GO:0007001);nucleosome assembly (GO:0006334) Bipartite nuclear localization signal (IPR001472);Histone H2B (IPR000558);Histone core (IPR007125);Histone-fold/TFIID-TAF/NF-Y (IPR007124) high 3.66781304826 206681_x_at GP2 GP2;ZAP75 glycoprotein 2 (zymogen granule membrane) None EGF-like domain (IPR006209);Endoglin/CD105 antigen (IPR001507) high 3.65451565682 211811_s_at PCDHA5 CNR1;CNR2;CNR4;CNR5;CNR6;CNR7;CNR8;CNRN1;CNRN2;CNRN4;CNRN5;CNRN6;CNRN7;CNRN8;CNRS2;CNRS4;CNRS5;CNRS6;CNRS7;CNRS8;CRNR1;CRNR2;CRNR4;CRNR5;CRNR6;CRNR7;CRNR8;KIAA0345;MGC71598;PCDH-ALPHA-C1;PCDH-ALPHA-C2;PCDH-ALPHA1;PCDH-ALPHA10;PCDH-ALPHA11;PCDH-ALPHA12;PCDH protocadherin alpha 5 calcium ion binding (GO:0005509);cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);homophilic cell adhesion (GO:0007156);neurogenesis (GO:0007399);protein binding (GO:0005515) Bipartite nuclear localization signal (IPR001472);Cadherin (IPR002126);Mitochondrial substrate carrier (IPR001993) high 3.63769389354 221679_s_at ABHD6 ABHD6 abhydrolase domain containing 6 aromatic compound metabolism (GO:0006725);epoxide hydrolase activity (GO:0004301);hydrolase activity (GO:0016787);response to toxin (GO:0009636);xenobiotic metabolism (GO:0006805) Alpha/beta hydrolase (IPR003089);Alpha/beta hydrolase fold (IPR000073);Epoxide hydrolase (IPR000639);Esterase/lipase/thioesterase (IPR000379) high 3.63372100517 207798_s_at A2LP A2D;A2LG;A2LP;A2RP ataxin 2 related protein biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554) Ataxin-2, C-terminal (IPR009818);Ataxin-2, N-terminal (IPR009604);Proline-rich region (IPR000694) high 3.62969502456 215259_s_at IGSF4C IGSF4C;TSLL2 immunoglobulin superfamily, member 4C None Immunoglobulin C-2 type (IPR003598);Immunoglobulin subtype (IPR003599);Immunoglobulin-like (IPR007110);Immunoglobulin/major histocompatibility complex (IPR003006);Neurexin/syndecan/glycophorin C (IPR003585) high 3.6277947487 203213_at CDC2 CDC2;CDK1 cell division cycle 2, G1 to S and G2 to M ATP binding (GO:0005524);cyclin-dependent protein kinase activity (GO:0004693);cytokinesis (GO:0016288);protein amino acid phosphorylation (GO:0006468);protein kinase activity (GO:0004672);transferase activity (GO:0016740) Protein kinase (IPR000719);Serine/threonine protein kinase (IPR002290);Tyrosine protein kinase (IPR001245) high 3.62461555049 213566_at RNASE6 RNASE6;RNASEK6;RNS6;RNase k6;RNasek6 ribonuclease, RNase A family, k6 RNA catabolism (GO:0006401);defense response (GO:0006952);endonuclease activity (GO:0004519);hydrolase activity (GO:0016787);nucleic acid binding (GO:0003676);pancreatic ribonuclease activity (GO:0004522);ribonuclease activity (GO:0004540) Pancreatic ribonuclease (IPR001427) low -3.61471484711 221681_s_at DSPP DFNA39;DGI1;DPP;DSP;DSPP;DTDP2 dentin sialophosphoprotein calcium ion binding (GO:0005509);collagen binding (GO:0005518);development (GO:0007275);extracellular matrix structural constituent (GO:0005201);perception of sound (GO:0007605);skeletal development (GO:0001501) None low -3.61718181645 212339_at EPB41L1 4.1N;EPB41L1;KIAA0338;MGC11072 erythrocyte membrane protein band 4.1-like 1 actin binding (GO:0003779);cortical actin cytoskeleton organization and biogenesis (GO:0030866);structural molecule activity (GO:0005198) 4.1, C-terminal (IPR008379);Band 4.1 (IPR000299);Ezrin/radixin/moesin ERM (IPR000798);FERM (IPR009065);SAB (IPR007477) low -3.62740652865 214545_s_at PROSC PROSC proline synthetase co-transcribed homolog (bacterial) alanine racemase activity (GO:0008784);biological_process unknown (GO:0000004);molecular_function unknown (GO:0005554);pyridoxal phosphate binding (GO:0030170) Alanine racemase, N-terminal (IPR001608) low -3.63055479344 217218_at KIAA0261 FOE;KIAA0261 KIAA0261 None Bipartite nuclear localization signal (IPR001472) low -3.63585161104 206392_s_at RARRES1 RARRES1;TIG1 retinoic acid receptor responder (tazarotene induced) 1 negative regulation of cell proliferation (GO:0008285);receptor activity (GO:0004872) Latexin (IPR009684) low -3.63683321179 218427_at SDCCAG3 NY-CO-3;SDCCAG3 serologically defined colon cancer antigen 3 tumor antigen (GO:0008222) None low -3.63904284805 207037_at TNFRSF11A EOF;FEO;ODFR;OFE;PDB2;RANK;TNFRSF11A;TRANCER tumor necrosis factor receptor superfamily, member 11a, activator of NFKB DNA binding (GO:0003677);cell-cell signaling (GO:0007267);immune response (GO:0006955);perception of sound (GO:0007605);positive regulation of cell proliferation (GO:0008284);receptor activity (GO:0004872);signal transduction (GO:0007165) TNFR/CD27/30/40/95 cysteine-rich region (IPR001368) low -3.65790961 gnf1h04161_at gnf1h04161_at None None None None low -3.66118155835 204338_s_at RGS4 MGC2124;MGC60244;RGP4;RGS4 regulator of G-protein signalling 4 GTPase activator activity (GO:0005096);calmodulin binding (GO:0005516);regulation of G-protein coupled receptor protein signaling pathway (GO:0008277);signal transducer activity (GO:0004871);signal transduction (GO:0007165) Bipartite nuclear localization signal (IPR001472);Regulator of G protein (IPR000342) low -3.70024962227 207603_at SLC4A7 NBC2;NBC3;SBC2;SLC4A6;SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 anion transport (GO:0006820);bicarbonate transport (GO:0015701);inorganic anion exchanger activity (GO:0005452);sodium:bicarbonate symporter activity (GO:0008510) Anion exchange protein (IPR001717);Bipartite nuclear localization signal (IPR001472);HCO3- transporter (IPR003020);Na+/HCO3- co-transporter (IPR003024) low -3.70265993524 gnf1h06265_at DP1L1 DP1L1 polyposis locus protein 1-like 1 None Di-copper centre-containing (IPR008922);TB2/DP1 and HVA22 related protein (IPR004345) low -3.71978013366 208192_at M84605 None None G-protein coupled receptor protein signaling pathway (GO:0007186);tachykinin receptor activity (GO:0004995);transmembrane receptor activity (GO:0004888) Rhodopsin-like GPCR superfamily (IPR000276) low -3.74818339305 gnf1h08542_s_at gnf1h08542_s_at None None None None low -3.75611734781 217077_s_at GPR51 GABABR2;GABBR2;GPR51;GPRC3B;HG20 G protein-coupled receptor 51 G-protein coupled receptor protein signaling pathway (GO:0007186);GABA-B receptor activity (GO:0004965);negative regulation of adenylate cyclase activity (GO:0007194) Extracellular ligand-binding receptor (IPR001828);G-protein coupled receptor family 3, metabotropic glutamate receptor-like (IPR000337);Metabotropic gamma-aminobutyric acid receptor, type B (IPR002455);Metabotropic gamma-aminobutyric acid receptor, type B1 (IPR002456);Metabotropic gamma-aminobutyric acid receptor, type B2 (IPR002457);Proline-rich region (IPR000694) low -3.76747110338 217294_s_at U88968 None None None None low -3.77653370421 205549_at PCP4 PCP4;PEP-19 Purkinje cell protein 4 None IQ calmodulin-binding region (IPR000048) low -3.80218376156 221935_s_at MGC34132 MGC34132 hypothetical protein MGC34132 None None low -3.81378023756 209243_s_at PEG3 KIAA0287;PEG3;PW1;ZIM2 paternally expressed 3 DNA binding (GO:0003677);signal transducer activity (GO:0004871);transcription factor activity (GO:0003700);zinc ion binding (GO:0008270) KRAB box (IPR001909);Transcriptional regulator SCAN (IPR003309);Zn-finger, C2H2 type (IPR007087) low -3.8208470142 210285_x_at WTAP KIAA0105;MGC3925;WTAP Wilms tumor 1 associated protein None None low -3.83245132806 215465_at ABCA12 ABCA12;DKFZP434G232;DKFZp434G232;ICR2B;LI2 ATP-binding cassette, sub-family A (ABC1), member 12 ATP binding (GO:0005524);ATP-binding cassette (ABC) transporter activity (GO:0004009);nucleotide binding (GO:0000166);transport (GO:0006810) AAA ATPase (IPR003593);ABC transporter (IPR003439);Bipartite nuclear localization signal (IPR001472) low -3.85998441569 217356_s_at PGK1 PGK1;PGKA phosphoglycerate kinase 1 glycolysis (GO:0006096);phosphoglycerate kinase activity (GO:0004618);transferase activity (GO:0016740) Phosphoglycerate kinase (IPR001576) low -3.89649759071 205751_at SH3GL2 CNSA2;EEN-B1;SH3D2A;SH3GL2;SH3P4 SH3-domain GRB2-like 2 acyltransferase activity (GO:0008415);endocytosis (GO:0006897);lipid binding (GO:0008289);signal transduction (GO:0007165);transferase activity (GO:0016740) BAR (IPR006632);Bipartite nuclear localization signal (IPR001472);Neutrophil cytosol factor 2 (IPR000108);SH3 (IPR001452) low -3.91536467044 gnf1h03546_at gnf1h03546_at None None None None low -3.96735486419 205061_s_at PMSCL1 PM/Scl-75;PMSCL1;RRP45;Rrp45p polymyositis/scleroderma autoantigen 1, 75kDa 3'-5'-exoribonuclease activity (GO:0000175);RNA binding (GO:0003723);RNA processing (GO:0006396);exonuclease activity (GO:0004527);hydrolase activity (GO:0016787);immune response (GO:0006955);rRNA processing (GO:0006364) 3' exoribonuclease (IPR001247) low -3.96773514098 gnf1h08305_at GARNL3 DKFZp761J1523;GARNL3;bA356B19.1 GTPase activating RANGAP domain-like 3 small GTPase regulatory/interacting protein activity (GO:0005083) Bipartite nuclear localization signal (IPR001472);Citron-like (IPR001180);Rap/ran-GAP (IPR000331) low -4.13653769844 214954_at KIAA0527 KIAA0527 KIAA0527 protein cell adhesion (GO:0007155);hyaluronic acid binding (GO:0005540) Link (IPR000538);Sushi domain/SCR domain/CCP module (IPR000436) low -4.2480380937 204143_s_at HSRTSBETA HSRTSBETA;RTS rTS beta protein catalytic activity (GO:0003824);metabolism (GO:0008152) Mandelate racemase/muconate lactonizing enzyme (IPR001354) low -4.34453285002 gnf1h09848_s_at SLC25A21 ODC;ODC1;SLC25A21 solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 binding (GO:0005488);transport (GO:0006810) Mitochondrial carrier protein (IPR002067);Mitochondrial substrate carrier (IPR001993) low -4.47863643753 214370_at S100A8 60B8AG;CAGA;CFAG;CGLA;CP-10;L1Ag;MA387;MIF;MRP8;NIF;S100A8 S100 calcium binding protein A8 (calgranulin A) calcium ion binding (GO:0005509);inflammatory response (GO:0006954) Calcium-binding EF-hand (IPR002048);Calcium-binding protein, S-100/ICaBP type (IPR001751) low -4.59216186652 201926_s_at DAF CD55;DAF decay accelerating factor for complement (CD55, Cromer blood group system) None Sushi domain/SCR domain/CCP module (IPR000436) low -4.73066041634 gnf1h01498_x_at gnf1h01498_x_at None None None None low -4.82156933163 211427_s_at KCNJ13 KCNJ13;KIR1.4;KIR7.1;MGC33328 potassium inwardly-rectifying channel, subfamily J, member 13 inward rectifier potassium channel activity (GO:0005242);ion transport (GO:0006811);potassium channel activity (GO:0005267);potassium ion transport (GO:0006813);voltage-gated ion channel activity (GO:0005244) Heat shock protein DnaJ, N-terminal (IPR001623);K+ channel, inward rectifier (IPR001838);K+ channel, pore region (IPR001622);Kir7 inward rectifier K+ channel (IPR008062) low -4.8540936921 207788_s_at SCAM-1 SCAM-1 vinexin beta (SH3-containing adaptor molecule-1) cell adhesion (GO:0007155);cell adhesion molecule activity (GO:0005194);protein binding (GO:0005515);structural constituent of cytoskeleton (GO:0005200) Neutrophil cytosol factor 2 (IPR000108);SH3 (IPR001452);Sorbin-like (IPR003127) low -5.4160866347 204548_at STAR STAR;STARD1 steroidogenic acute regulator C21-steroid hormone biosynthesis (GO:0006700);cholesterol binding (GO:0015485);cholesterol transporter activity (GO:0017127);lipid binding (GO:0008289);lipid transport (GO:0006869);steroid biosynthesis (GO:0006694) Lipid-binding START (IPR002913);Steroidogenic acute regulatory protein (IPR000799) low -6.62564613449 207980_s_at CITED2 CITED2;MRG1;P35SRJ Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 protein binding (GO:0005515);transcription factor activity (GO:0003700) CITED (IPR007576)