-
cdef extern from "string.h":
ctypedef int size_t
void *memcpy(void *dst,void *src,size_t len)
void qsort(void *base, size_t nmemb, size_t size,
int (*compar)(void *,void *))
+cdef extern from "math.h":
+ double sqrt(double x)
+
cdef extern from "stdio.h":
ctypedef struct FILE:
pass
FILE * stdout
int fclose(FILE *)
int sscanf(char *str,char *fmt,...)
- int printf(char *str,char *fmt,...)
+ int printf(char *fmt,...)
int sprintf(char *str,char *fmt,...)
int fprintf(FILE *ifile,char *fmt,...)
char *fgets(char *str,int size,FILE *ifile)
size_t strlen(char *s)
int memcmp( void * s1, void *s2, size_t len )
+cdef extern from "Python.h":
+ long _Py_HashPointer(void*)
+ FILE* PyFile_AsFile(object)
+
+cdef extern from "fileobject.h":
+ ctypedef class __builtin__.file [object PyFileObject]:
+ pass
+
cdef extern from "razf.h":
pass
ctypedef int uint8_t
ctypedef int uint64_t
-
cdef extern from "bam.h":
+ # constants
+ int BAM_DEF_MASK
# IF _IOLIB=2, bamFile = BGZF, see bgzf.h
# samtools uses KNETFILE, check how this works
ctypedef struct bam_plbuf_t:
pass
+ ctypedef struct pair64_t:
+ uint64_t u, v
+
+ ctypedef struct bam_iter_t:
+ int from_first
+ int tid, beg, end, n_off, i, finished
+ uint64_t curr_off
+ pair64_t *off
+
+ # ctypedef __bam_iter_t * bam_iter_t
+
+ bam1_t * bam_init1()
+ void bam_destroy1(bam1_t *)
+
bamFile razf_dopen(int data_fd, char *mode)
- # removed - macros not found
+ int64_t bam_seek( bamFile fp, uint64_t voffset, int where)
+ int64_t bam_tell( bamFile fp )
- # int64_t bam_seek( bamFile fp, uint64_t voffset, int where)
- # int64_t bam_tell( bamFile fp )
- # void bam_destroy1( bam1_t * b)
# void bam_init_header_hash(bam_header_t *header)
+ ###############################################
+ # stand-ins for samtools macros
+ uint32_t * bam1_cigar( bam1_t * b)
+ char * bam1_qname( bam1_t * b)
+ uint8_t * bam1_seq( bam1_t * b)
+ uint8_t * bam1_qual( bam1_t * b)
+ uint8_t * bam1_aux( bam1_t * b)
+
+ ###############################################
+ # bam iterator interface
+ bam_iter_t bam_iter_query( bam_index_t *idx, int tid, int beg, int end)
+
+ int bam_iter_read(bamFile fp, bam_iter_t iter, bam1_t *b)
+
+ void bam_iter_destroy(bam_iter_t iter)
+
+ ###############################################
+
bam1_t * bam_dup1( bam1_t *src )
bam1_t * bam_copy1(bam1_t *bdst, bam1_t *bsrc)
int bam_parse_region(bam_header_t *header, char *str, int *ref_id, int *begin, int *end)
+ ###############################################
bam_plbuf_t *bam_plbuf_init(bam_pileup_f func, void *data)
int bam_fetch(bamFile fp, bam_index_t *idx, int tid, int beg, int end, void *data, bam_fetch_f func)
int bam_plbuf_push(bam1_t *b, bam_plbuf_t *buf)
void bam_plbuf_destroy(bam_plbuf_t *buf)
+ ########################################
+ # pileup iterator interface
+ ctypedef struct bam_plp_t:
+ pass
+
+ ctypedef bam_pileup1_t * const_bam_pileup1_t_ptr "const bam_pileup1_t *"
+
+ ctypedef int (*bam_plp_auto_f)(void *data, bam1_t *b)
+
+ bam_plp_t bam_plp_init( bam_plp_auto_f func, void *data)
+ int bam_plp_push( bam_plp_t iter, bam1_t *b)
+ bam_pileup1_t * bam_plp_next( bam_plp_t iter, int *_tid, int *_pos, int *_n_plp)
+ bam_pileup1_t * bam_plp_auto( bam_plp_t iter, int *_tid, int *_pos, int *_n_plp)
+ void bam_plp_set_mask(bam_plp_t iter, int mask)
+ void bam_plp_reset(bam_plp_t iter)
+ void bam_plp_destroy(bam_plp_t iter)
- int bam_read1(bamFile fp, bam1_t *b)
+ ##################################################
+ int bam_read1( bamFile fp, bam1_t *b)
+ int bam_validate1( bam_header_t *header, bam1_t *b)
int bam_write1( bamFile fp, bam1_t *b)
bam_header_t *bam_header_init()
uint8_t *bam_aux_get(bam1_t *b, char tag[2])
- int bam_aux2i(uint8_t *s)
+ int32_t bam_aux2i(uint8_t *s)
float bam_aux2f(uint8_t *s)
double bam_aux2d(uint8_t *s)
char bam_aux2A( uint8_t *s)
uint32_t bam_calend(bam1_core_t *c, uint32_t *cigar)
+cdef extern from *:
+ ctypedef char* const_char_ptr "const char*"
+
cdef extern from "sam.h":
ctypedef struct samfile_t_un:
samfile_t_un x
bam_header_t *header
- samfile_t *samopen( char *fn, char * mode, void *aux)
+ samfile_t *samopen( const_char_ptr fn, char * mode, void *aux)
int sampileup( samfile_t *fp, int mask, bam_pileup_f func, void *data)
int samwrite(samfile_t *fp, bam1_t *b)
+ int bam_prob_realn(bam1_t *b, char *ref)
+ int bam_cap_mapQ(bam1_t *b, char *ref, int thres)
+
+
+cdef extern from "glf.h":
+ ctypedef struct glf1_t:
+ pass
+
+cdef extern from "bam_maqcns.h":
+
+ ctypedef struct bam_maqcns_t:
+ float het_rate, theta
+ int n_hap, cap_mapQ, errmod, min_baseQ
+ float eta, q_r
+ double *fk, *coef
+ double *lhet
+ void *aux
+
+ glf1_t *bam_maqcns_glfgen(int n,
+ bam_pileup1_t *pl,
+ uint8_t ref_base,
+ bam_maqcns_t *bm)
+
+ ctypedef struct bam_maqindel_opt_t:
+ int q_indel
+ float r_indel
+ float r_snp
+ int mm_penalty, indel_err, ambi_thres
+
+ uint32_t bam_maqcns_call(int n, bam_pileup1_t *pl, bam_maqcns_t *bm)
+ bam_maqcns_t * bam_maqcns_init()
+ void bam_maqcns_destroy(bam_maqcns_t *bm)
+ void bam_maqcns_prepare(bam_maqcns_t *bm)
+
+ uint32_t glf2cns(glf1_t *g, int q_r)
+
+ int BAM_ERRMOD_MAQ2
+ int BAM_ERRMOD_MAQ
+ int BAM_ERRMOD_SOAP
+
+ ctypedef struct bam_maqindel_ret_t:
+ int indel1
+ int indel2
+ int cnt1
+ int cnt2
+ int cnt_anti
+ int cnt_ref
+ int cnt_ambi
+ char *s[2]
+ int gt
+ int gl[2]
+ int q_cns
+ int q_ref
+
+ void bam_maqindel_ret_destroy( bam_maqindel_ret_t * )
+
+ bam_maqindel_opt_t *bam_maqindel_opt_init()
+
+ bam_maqindel_ret_t * bam_maqindel(int n,
+ int pos,
+ bam_maqindel_opt_t * mi,
+ bam_pileup1_t * pl,
+ char *ref,
+ int _n_types,
+ int * _types )
+
+
cdef extern from "faidx.h":
ctypedef struct faidx_t:
char *fai_fetch(faidx_t *fai, char *reg, int *len)
-cdef extern from "pysam_util.h":
+ int faidx_fetch_nseq(faidx_t *fai)
- int pysam_bam_plbuf_push(bam1_t *b, bam_plbuf_t *buf, int cont)
+ char *faidx_fetch_seq(faidx_t *fai, char *c_name,
+ int p_beg_i, int p_end_i, int *len)
- int pysam_get_pos( bam_plbuf_t *buf)
- int pysam_get_tid( bam_plbuf_t *buf)
+cdef extern from "pysam_util.h":
+
+ int pysam_pileup_next(bam1_t *b,
+ bam_plbuf_t *buf,
+ bam_pileup1_t ** plp,
+ int * tid,
+ int * pos,
+ int * n_plp )
- bam_pileup1_t * pysam_get_pileup( bam_plbuf_t *buf)
int pysam_dispatch(int argc, char *argv[] )
# translate char to unsigned char
unsigned char pysam_translate_sequence( char s )
- # stand-ins for samtools macros
- uint32_t * pysam_bam1_cigar( bam1_t * b)
- char * pysam_bam1_qname( bam1_t * b)
- uint8_t * pysam_bam1_seq( bam1_t * b)
- uint8_t * pysam_bam1_qual( bam1_t * b)
- uint8_t * pysam_bam1_aux( bam1_t * b)
+ unsigned char * bam_nt16_table
+
+ int pysam_reference2tid( bam_header_t *header, char * s )
+
+ void pysam_set_stderr( FILE * file )
+
+ uint32_t pysam_glf_depth( glf1_t * g )
+
+ void pysam_dump_glf( glf1_t * g, bam_maqcns_t * c )
+
+# need to declare all C fields and methods here
+cdef class AlignedRead:
+
+ # object that this AlignedRead represents
+ cdef bam1_t * _delegate
+
+cdef class Samfile:
+ cdef char * _filename
+ # pointer to samfile
+ cdef samfile_t * samfile
+ # pointer to index
+ cdef bam_index_t *index
+ # true if file is a bam file
+ cdef int isbam
+ # true if file is not on the local filesystem
+ cdef int isremote
+ # current read within iteration
+ cdef bam1_t * b
+ # file opening mode
+ cdef char * mode
+
+ cdef bam_header_t * _buildHeader( self, new_header )
+ cdef bam1_t * getCurrent( self )
+ cdef int cnext(self)
+
+ # write an aligned read
+ cpdef int write( self, AlignedRead read )
+
+ cdef char * _getrname( self, int tid )
- # iterator implemenation
- ctypedef struct bam_fetch_iterator_t:
- pass
-
- bam_fetch_iterator_t* bam_init_fetch_iterator(bamFile fp, bam_index_t *idx, int tid, int beg, int end)
-
- bam1_t * bam_fetch_iterate(bam_fetch_iterator_t *iter)
-
- void bam_cleanup_fetch_iterator(bam_fetch_iterator_t *iter)
projects / pysam.git / blobdiff